Welcome to Paperity

The first multidisciplinary aggregator of Open Access journals and papers. Keep on top of recent discoveries and never hit a paywall.

Learn more »

Recently added

Differential analysis of chromatin accessibility and histone modifications for predicting mouse developmental enhancers

Enhancers are distal cis-regulatory elements that modulate gene expression. They are depleted of nucleosomes and enriched in specific histone modifications; thus, calling DNase-seq and histone mark ChIP-seq peaks can predict enhancers. We evaluated nine peak-calling algorithms for predicting enhancers validated by transgenic mouse assays. DNase and H3K27ac peaks were consistently...

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro Su Hu,1,* Li Xu,1,2,* Lihua Li,1 Dongdong Luo,1 Hailin Zhao,1 Dan Li,1 Biao Peng1 1Department of Neurosurgery, The Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong, People’s Republic of China; 2Department of Neurosurgery, The Central...

Allegedly

Mary Addison killed a baby when she was nine years old. Allegedly. Now fifteen, Mary is out of “baby jail,” but lives in a group home for teenage girls with criminal records. Though she is supposed to have many advocates in her life, none of the professionals assigned to her case seem to care at all. Consequently, Mary lives a cold and tortured life. When she discovers she is...

Onboard experiment investigating metal leaching of fresh hydrothermal sulfide cores into seawater

We observed the initial release rate of metals from four fresh (i.e., without long time exposure to the atmosphere) hydrothermal sulfide cores into artificial seawater. The sulfide samples were collected by seafloor drilling from the Okinawa Trough by D/V Chikyu, powdered under inert gas, and immediately subjected to onboard metal-leaching experiments at different temperatures (5...

Bartholomew Biddle and the Very Big Wind

Bartholomew Biddle is a boy who hates math and loves adventure, but soon finds himself being swept up by his trusty bedsheet and a powerful gust of wind. As Bart travels and meets new friends in strange lands he must decide where he truly belongs among pirates, pilots, parents, and friends. What will he do when he finds himself where the wind doesn't blow--will he return home...

Can'ts and Don'ts

By Bill Elgersma, Published on 12/01/18

Topical anesthesia therapy using lidocaine-loaded nanostructured lipid carriers: tocopheryl polyethylene glycol 1000 succinate-modified transdermal delivery system

Topical anesthesia therapy using lidocaine-loaded nanostructured lipid carriers: tocopheryl polyethylene glycol 1000 succinate-modified transdermal delivery system Xiangju Zhao, Ying Sun, Zhaoguo Li Department of Anesthesiology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, People’s Republic of China Purpose: Transdermal drug delivery of local...

Post-marketing surveillance study of the safety of dexamethasone intravitreal implant in patients with retinal vein occlusion or noninfectious posterior segment uveitis

Post-marketing surveillance study of the safety of dexamethasone intravitreal implant in patients with retinal vein occlusion or noninfectious posterior segment uveitis Adnan Tufail,1 Sue Lightman,1 Ahmed Kamal,2 Uwe Pleyer,3 Nuria María Gajate Paniagua,4 Corrine Dot,5,6 Xiao-Yan Li,7 Jenny Jiao,7 Jean Lou,7 Yehia Hashad7For the CONSTANCE Study Group1Moorfields Eye Hospital...

Combined perventricular closure of ventricular septal defect and atrial septal defect via lower ministernotomy

Minimally invasive approaches such as perventricular closure of ventricular septal defects (VSD) have been applied for the surgical correction of congenital heart defects in order to avoid disadvantages related to median sternotomy with a cardiopulmonary bypass (CPB). However, reports remain scarce regarding combined perventricular closure of VSD and atrial septal defects (ASD...

Baerveldt or Ahmed glaucoma valve implantation with pars plana tube insertion in Japanese eyes with neovascular glaucoma: 1-year outcomes

Baerveldt or Ahmed glaucoma valve implantation with pars plana tube insertion in Japanese eyes with neovascular glaucoma: 1-year outcomes Masayo Suda, Hideo Nakanishi, Tadamichi Akagi, Tomoaki Murakami, Kiyoshi Suzuma, Kenji Suda, Takanori Kameda, Satoshi Morooka, Hanako Ohashi Ikeda, Akitaka Tsujikawa Department of Ophthalmology and Visual Sciences, Kyoto University Graduate...

Stabbing Rectangles by Line Segments - How Decomposition Reduces the Shallow-Cell Complexity

We initiate the study of the following natural geometric optimization problem. The input is a set of axis-aligned rectangles in the plane. The objective is to find a set of horizontal line segments of minimum total length so that every rectangle is stabbed by some line segment. A line segment stabs a rectangle if it intersects its left and its right boundary. The problem, which...

Neue EAACI-Definition der Pollensaison klinisch relevant

2017 hat die European Academy of Allergy and Clinical Immunology die Definition für die Birken- und Gräserpollenflugsaison neu festgelegt. Eine Studie überprüfte die Korrelation der Definition anhand von Pollenzählungen mit der klinischen Symptomatik.

What’s the potential for environmental DNA (eDNA) to assess stygofauna and trogolofauna: pilot studies from Western Australia

Biological organisms living in any environment can expel DNA into their surroundings through fecal matter, mucus, shed skin, gametes, etc. Here we examine the utility of metabarcoding from a variety of environmental DNA (eDNA) substrates collected from the Pilbara region, Western Australia, to assess the feasibility for both stygo- and troglofauna detection. With metabarcoding...

If the World Were a Village: A Book about the World’s People

This text provides statistics as to the characteristics of the population of the world represented as a village of one hundred people. The book notes important data concerning the population growth of the village, natural resources available to different groups of people, distribution of wealth and food, languages spoken, and so forth. A wonderful teaching tool, the statistics...

Popular Matchings in Complete Graphs

Our input is a complete graph G = (V,E) on n vertices where each vertex has a strict ranking of all other vertices in G. The goal is to construct a matching in G that is "globally stable" or popular. A matching M is popular if M does not lose a head-to-head election against any matching M': here each vertex casts a vote for the matching in {M,M'} where it gets a better assignment...

ADAR1 silencing-induced HUVEC apoptosis is mediated by FGFR2 under hypoxia stress

ADAR1 silencing-induced HUVEC apoptosis is mediated by FGFR2 under hypoxia stress Yun Jiang,1 Zhancheng Wang,1 Xu Chen,1 Wei Wang,1 Xiaowei Wang2 1Department of Cardiology, The Eighth People’s Hospital of Shanghai, Shanghai 200233, China; 2Shanghai Weiang Info Tech Ltd., Shanghai 200233, China Background: The adenosine deaminase acting on RNA 1 (ADAR1) specifically deaminates...

Cost-effectiveness of continuity of midwifery care for women with complex pregnancy: a structured review of the literature

BackgroundCritical evaluation of the cost-effectiveness and clinical effectiveness of continuity of midwifery care models for women experiencing complex pregnancy is an important consideration in the review and reform of maternity services. Most studies either focus on women who experience healthy pregnancy or mixed risk samples. These results may not be generalised across the...

Transformation #2

By David Versluis, Published on 12/01/18

Endoscopic submucosal dissection followed by chemoradiotherapy for superficial esophageal cancer: choice of new approach

The standard treatment for superficial esophageal cancer (SEC) involving muscularis mucosal (T1a-MM) or submucosal (T1b) invasion has been the surgical resection of the esophagus. However, esophagectomy with extended lymph node dissection is highly invasive. Recent reports have shown that endoscopic submucosal dissection (ESD) followed by chemoradiotherapy (CRT) has promising...

Effect of Levothyroxine Treatment on Incident Dementia in Adults with Atrial Fibrillation and Hypothyroidism

Background and ObjectiveThe possible adverse or positive effects of levothyroxine treatment among patients with atrial fibrillation have been debated. Atrial fibrillation, levothyroxine treatment, and dementia are common among older adults, yet little is known about the effects of levothyroxine on the development of dementia.MethodsThe study population included all adults (n = 12...

A comparative study of toxicity of TiO2, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells

A comparative study of toxicity of TiO2, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells Maolin Wang,1,* Qianyu Yang,1,* Jimin Long,1 Yanghuai Ding,1 Xiaoqing Zou,1 Guochao Liao,2 Yi Cao1 1Key Laboratory of Environment-Friendly Chemistry and Application of Ministry of Education, Laboratory of Biochemistry, College of Chemistry, Xiangtan University, Xiangtan, Hunan...

Peru since Independence, a Tortured History

This essay reviews the following works: The Lima Reader: History, Culture, Politics. Edited by Carlos Aguirre and Charles Walker. Durham, NC: Duke University Press, 2017, Pp. xv + 272. $26.95 paperback. ISBN: 9780822363484. Perú. 5 tomos. America Latina en la historia contemporánea. Dirigido por Carlos Contreras Carranza. Madrid: Fundación MAPFRE, 2013–2015. Tomo 1, Crisis...

Dual-phase [18F]florbetapir in frontotemporal dementia

PurposeThe PET tracer [18F]florbetapir is a specific fibrillar amyloid-beta (Aβ) biomarker. During the late scan phase (> 40 min), it provides pathological information about Aβ status. Early scan phase (0–10 min) can provide FDG-‘like’ information. The current investigation tested the feasibility of using florbetapir as a dual-phase biomarker in behavioural variant frontotemporal...

Dosimetric evaluation of the compass program for patient dose analysis in IMRT delivery quality assurance

A practical method was designed to verify the accuracy of dose distributions calculated using Compass, which can reconstruct the dose distribution inside a patient’s body during intensity-modulated radiation therapy (IMRT). Twelve virtual IMRT treatment plans were developed using an ArcCHECK diode detector array, and then the recalculated and reconstructed doses in Compass were...

Home-based visual field test for glaucoma screening comparison with Humphrey perimeter

Home-based visual field test for glaucoma screening comparison with Humphrey perimeter Stylianos Tsapakis, Dimitrios Papaconstantinou, Andreas Diagourtas, Stylianos Kandarakis, Konstantinos Droutsas, Konstantinos Andreanos, Dimitrios Brouzas 1st Department of Ophthalmology, National and Kapodistrian University of Athens, Athens, Greece Purpose: To present a home-based visual...

A survey of basal insects (Microcoryphia and Zygentoma) from subterranean environments of Iran, with description of three new species

A survey of wingless insects belonging to the orders Microcoryphia (=Archaeognatha) and Zygentoma (=Thysanura s. str.) has been performed in subterranean habitats of central Iran. As a result, several new species have been discovered. In this work, three new species are described: a new species of bristletail of the family Machilidae, Haslundiella iranica sp. n., a new silverfish...

Graph Pattern Polynomials

Given a host graph G and a pattern graph H, the induced subgraph isomorphism problem is to decide whether G contains an induced subgraph that is isomorphic to H. We study the time complexity of induced subgraph isomorphism problems when the pattern graph is fixed. Nesetril and Poljak gave an O(n^{k omega}) time algorithm that decides the induced subgraph isomorphism problem for...

Full List of Papers »