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2500-g Low Birth Weight Cutoff: History and Implications for Future Research and Policy

Maternal and Child Health Journal, Jul 23, Michelle M. Hughes, Robert E. Black, Joanne Katz

Purpose To research the origins of the 2500 g cutoff for low birth weight and the evolution of indicators to identify newborns at high mortality risk. Description Early research concluded “prematurity”, measured mainly through birth weight, was responsible for increased health risks. The World Health Organization’s original prematurity definition was birth weight ≤2500 g. 1960s ...

Frequent co-expression of EGFR and NeuGcGM3 ganglioside in cancer: it’s potential therapeutic implications

Clinical & Experimental Metastasis, Jul 23, Addys González Palomo, Rancés Blanco Santana, Xiomara Escobar Pérez, et al.

Interaction between epidermal growth factor receptor (EGFR) signaling with GM3 ganglioside expression has been previously described. However, little is known about EGFR and NeuGcGM3 co-expression in cancer patients and their therapeutic implications. In this paper, we evaluate the co-expression of EGFR and NeuGcGM3 ganglioside in tumors from 92 patients and in two spontaneous lung ...

Transverse pion structure beyond leading twist in constituent models

The European Physical Journal C, Jul 01, C. Lorcé, B. Pasquini, P. Schweitzer

The understanding of the pion structure as described in terms of transverse-momentum-dependent parton distribution functions (TMDs) is of importance for the interpretation of currently ongoing Drell–Yan experiments with pion beams. In this work we discuss the description of pion TMDs beyond leading twist in a pion model formulated in the light-front constituent framework. For ...

Abortion and miscarriage

Philosophical Studies, Jul 22, Amy Berg

Opponents of abortion sometimes hold that it is impermissible because fetuses are persons from the moment of conception. But miscarriage, which ends up to 89 % of pregnancies, is much deadlier than abortion. That means that if opponents of abortion are right, then miscarriage is the biggest public-health crisis of our time. Yet they pay hardly any attention to miscarriage, ...

Disseminated mucormycosis (DM) after pneumonectomy: a case report

BMC Infectious Diseases, Jul 22, Qian Wang, Bo Liu, Youde Yan

Background Mucormycosis is a kind of rare opportunistic fungal disease and the incidence of which has gradually increased. Disseminated mucormycosis (DM) is a life-threatening infection that mostly occurs in immunocompromised patients. The lung and brain are usually involved in disseminated mucormycosis, and other sites are scare. We report the first case of disseminated ...

An additive manufacturing filter for topology optimization of print-ready designs

Structural and Multidisciplinary Optimization, Jul 22, Matthijs Langelaar

Additive manufacturing (AM) offers exciting opportunities to manufacture parts of unprecedented complexity. Topology optimization is essential to fully exploit this capability. However, AM processes have specific limitations as well. When these are not considered during design optimization, modifications are generally needed in post-processing, which add costs and reduce the ...

Corn Crisps Enriched in Omega-3 Fatty Acids Sensory Characteristic and its Changes During Storage

Journal of the American Oil Chemists' Society, Jul 23, Mateusz Rogalski, Karolina Nowak, Piotr Fiedor, et al.

Extruded cereal snacks are usually deficient in protein, mineral ingredients, valuable fatty acids. With the rise of health awareness among consumers, food manufacturers and scientists are pressed to take measures in order to develop new functional/health-beneficial foods. The aim of this work was to manufacture extruded crisps enriched with α-linolenic acid (obtained from linseed ...

The ghrelin and leptin responses to short-term starvation vs a carbohydrate-free diet in men with type 2 diabetes; a controlled, cross-over design study

Nutrition & Metabolism, Jul 22, Frank Nuttall, Rami Almokayyad, Mary Gannon

Background We recently have reported the 24-hour glucose, insulin and glucagon responses to a 72-hour fast compared to a 72-hour macronutrient-sufficient, carbohydrate-free diet in men with type 2 diabetes. The 72-hour time period was used because it is the time required for the major metabolic adjustments to a lack of food to be instituted. As part of that study, ghrelin and ...

Copy number variants and rasopathies: germline KRAS duplication in a patient with syndrome including pigmentation abnormalities

Orphanet Journal of Rare Diseases, Jul 22, Brigitte Gilbert-Dussardier, Audrey Briand-Suleau, Ingrid Laurendeau, et al.

RAS/MAPK pathway germline mutations were described in Rasopathies, a class of rare genetic syndromes combining facial abnormalities, heart defects, short stature, skin and genital abnormalities, and mental retardation. The majority of the mutations identified in the Rasopathies are point mutations which increase RAS/MAPK pathway signaling. Duplications encompassing RAS/MAPK pathway ...

Enhancement of technical value of oil palm (Elaeis guineensis Jacq.) waste trunk through modification with 1,3-dimethylol-4,5-dihydroxyethyleneurea (DMDHEU)

European Journal of Wood and Wood Products, Jul 23, Mariusz Mamiński, Paweł Kozakiewicz, Waldemar Jaskółowski, et al.

Malaysia is the biggest producer of palm oil in the world. The production generates over 70 metric tons of waste trunks per hectare during replantation. Such an abundant feedstock should be considered a valuable raw material rather than an agro-waste. An approach for enhancement of low density trunks through the treatment with 1,3-dimethylol-4,5-dihydroxyethyleneurea (DMDHEU) was ...

Advancing the Progress of Mentoring for Diversity in AIDS Research: Warming the Mentoring Climate

AIDS and Behavior, Jul 23, Hannah A. Valantine

Critical Criminology as Academic Activism: On Praxis and Pedagogy, Resistance and Revolution

Critical Criminology, Jul 23, Bruce A. Arrigo

Why do family doctors prescribe potentially inappropriate medication to elderly patients?

BMC Family Practice, Jul 22, Karen Voigt, Mandy Gottschall, Juliane Köberlein-Neu, et al.

Background Based on changes in pharmacokinetics and –dynamics in elderly patients, there are potentially inappropriate medications (PIM) that should be avoided in patients aged ≥ 65 years. Current studies showed prescription rates of PIM between 22.5 and 28.4 % in the primary care setting. The evidence concerning reasons for PIM prescription by FPs is limited. Methods This mixed ...

Modeling of environmental impact assessment of Kolaghat thermal power plant area, West Bengal, using remote sensing and GIS techniques

Modeling Earth Systems and Environment, Jul 23, Ismail Mondal, Shibdas Maity, Biswanath Das, et al.

The Kolaghat Thermal Power Plant is a major Thermal Power Plant in West Bengal, India. It is located at Mecheda (approx.) and 55 km from Kolkata. It is situated on the right site of the Rup Narayan River bank which is under the district of Purba Medinipur, west Bengal. The Power Plant is operated by West Bengal Power Development Corporation. The Kolaghat Thermal Power Plant (KTPP) ...

Investigation of availability of a high throughput screening method for predicting butanol solvent -producing ability of Clostridium beijerinckii

BMC Microbiology, Jul 22, HaiFeng Su, Jun Zhu, Gang Liu, et al.

Background Currently, efficient screening methods for selection of desired bacterial phenotypes from large populations are not easy feasible or readily available due to the complicated physiological and metabolic networks of solventogenic clostridia. In this study, to contribute to the improvement of methods for predicting the butanol-producing ability of Clostridium beijerinckii ...

Risk, Liability, and Economic Issues with Long-Term CO2 Storage—A Review

Natural Resources Research, Jul 23, Steven T. Anderson

Given a scarcity of commercial-scale carbon capture and storage (CCS) projects, there is a great deal of uncertainty in the risks, liability, and their cost implications for geologic storage of carbon dioxide (CO2). The probabilities of leakage and the risk of induced seismicity could be remote, but the volume of geologic CO2 storage (GCS) projected to be necessary to have a ...

How clinical reasoning is taught and learned: Cultural perspectives from the University of Melbourne and Universitas Indonesia

BMC Medical Education, Jul 21, Ardi Findyartini, Lesleyanne Hawthorne, Geoff McColl, et al.

Background The majority of schools in the Asia-Pacific region have adopted medical curricula based on western pedagogy. However to date there has been minimal exploration of the influence of the culture of learning on the teaching and learning process. This paper explores this issue in relation to clinical reasoning. Method A comparative case study was conducted in 2 medical ...

Influenza Vaccination and Antiviral Therapy in Pregnant Women

Journal of Infectious Diseases, Jul 22, Alan T. N. Tita, William W. Andrews

Consequences of Fish Kills for Long-Term Trophic Structure in Shallow Lakes: Implications for Theory and Restoration

Ecosystems, Jul 22, Carl D. Sayer, Thomas A. Davidson, Ruth Rawcliffe, et al.

Fish kills are a common occurrence in shallow, eutrophic lakes, but their ecological consequences, especially in the long term, are poorly understood. We studied the decadal-scale response of two UK shallow lakes to fish kills using a palaeolimnological approach. Eutrophic and turbid Barningham Lake experienced two fish kills in the early 1950s and late 1970s with fish recovering ...

OSCAR-Na: A New Code for Simulating Corrosion Product Contamination in SFR

Metallurgical and Materials Transactions E, Jul 22, J.-B. Génin, L. Brissonneau, T. Gilardi

A code named OSCAR-Na has been developed to calculate the mass transfer of corrosion products in the primary circuit of sodium fast reactors (SFR). It is based on a solution/precipitation model, including diffusion in the steel (enhanced under irradiation), diffusion through the sodium boundary layer, equilibrium concentration of each element, and velocity of the interface (bulk ...

Antimicrobial resistance and Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) genotypes in N. gonorrhoeae during 2012–2014 in Karachi, Pakistan

BMC Infectious Diseases, Jul 22, Kauser Jabeen, Pushpa Bhawan Mal, Erum Khan, et al.

Background Globally, increasing antimicrobial resistance (AMR) in Neisseria gonorrhoea has led to decreased treatment options for gonorrhoea. Continuous monitoring of resistance is crucial to determine evolving resistance trends in Neisseria gonorrhoea and to suggest treatment recommendations. Quality assured gonococcal AMR data from Pakistan are mainly lacking. This study was ...

The ancient Syrian physician Archigenes and his contributions to neurology and neuroanatomy

Child's Nervous System, Jul 23, Michael James Montalbano, Amit Sharma, Rod J. Oskouian, et al.

N,O-codoped porous carbon nanosheets for capacitors with ultra-high capacitance

Science China Materials, Jul 20, Zhong Wu 吴中, Xin-bo Zhang 张新波

Significant enhancement of energy density of electrical double layered capacitors is a major challenge for electrochemical capacitors to conquer the emerging field of large scale renewable energy storage. The enhancement of specific capacitance is an effective strategy to obtain higher energy density. Addition of redox mediator in the electrolyte as pseudocapacitive sources could ...

The Coordination Abilities of New Cyclic Analogs of Somatostatin

International Journal of Peptide Research and Therapeutics, Jul 23, Aleksandra Marciniak, Marek Cebrat, Justyna Brasuń

Two new somatostatin analogs with a characteristic part of the sequence -c(Cys-Phe-Trp-Lys-Thr-Cys)- and with two histidine and two aspartic acid moieties in their structures were synthesized and analyzed in terms of their coordination abilities with copper (II) ions. Both peptides bind Cu(II) effectively. Ligands form 4N complexes with \(\left\{ {{\text{N}}_{\text{Im}} ,{ 3} ...

Gastrointestinal Safety of Aspirin for a High-Dose, Multiple-Day Treatment Regimen: A Meta-Analysis of Three Randomized Controlled Trials

Drugs in R&D, Jul 23, Samantha Forder, Michael Voelker, Angel Lanas

Background and Aim Aspirin is a commonly used over-the-counter (OTC) agent for the symptomatic treatment of acute pain, fever, or the common cold, but data regarding safety in this context are limited. In order to characterize the safety of aspirin beyond single-dose or long-term use data, we conducted a meta-analysis of multiple-dose, multiple-day studies of OTC aspirin at a ...

Dietary supplementation with Bifidobacterium longum subsp. infantis (B. infantis) in healthy breastfed infants: study protocol for a randomised controlled trial

Trials, Jul 22, Smita Awasthi, Reason Wilken, Forum Patel, et al.

Background The development of probiotics as therapies to cure or prevent disease lags far behind that of other investigational medications. Rigorously designed phase I clinical trials are nearly non-existent in the field of probiotic research, which is a contributing factor to this disparity. As a consequence, how to appropriately dose probiotics to study their efficacy is unknown. ...

Are we “preparing” radiopharmaceuticals?

EJNMMI Radiopharmacy and Chemistry, Jul 23, Clemens Decristoforo, Marianne Patt

Use of geographic indicators of healthcare, environment and socioeconomic factors to characterize environmental health disparities

Environmental Health, Jul 22, Cindy Padilla, Wahida Kihal-Talantikit, Sandra Perez, et al.

Background An environmental health inequality is a major public health concern in Europe. However just few studies take into account a large set of characteristics to analyze this problematic. The aim of this study was to identify and describe how socioeconomic, health accessibility and exposure factors accumulate and interact in small areas in a French urban context, to assess ...

Designed for a Range of Tasks

IST International Surface Technology, Jul 01, Yaskawa Europe GmbH

Mechanical ventilation strategies for intensive care unit patients without acute lung injury or acute respiratory distress syndrome: a systematic review and network meta-analysis

Critical Care, Jul 22, Lei Guo, Weiwei Wang, Nana Zhao, et al.

Background It has been shown that the application of a lung-protective mechanical ventilation strategy can improve the prognosis of patients with acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). However, the optimal mechanical ventilation strategy for intensive care unit (ICU) patients without ALI or ARDS is uncertain. Therefore, we performed a network ...

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