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Performance evaluation of household water treatment systems used in Kerman for removal of cations and anions from drinking water

Increased awareness in society of the consequences of contaminants in drinking water has created a demand for household water treatment systems, which provide higher quality water, to spread. The aim of this study was to evaluate the performance of household water treatment systems used in Kerman for the removal of cations and anions. Various brands of home water treatment devices ...

Assessing the ecological vulnerability of the upper reaches of the Minjiang River

The upper reaches of the Minjiang River (URMR), located on the eastern edge of the Tibetan Plateau in southwestern China, are an important component of the ecological barrier of the Upper Yangtze River Basin. Climate change and human activities have increased the ecological sensitivity and vulnerability of the region, which may pose a threat to the ecological security of the ...

Confirmation of independent introductions of an exotic plant pathogen of Cornus species, Discula destructiva, on the east and west coasts of North America

Cornus florida (flowering dogwood) and C. nuttallii (Pacific dogwood) are North American native tree species that belong to the big-bracted group of dogwoods. Cornus species are highly valued for their ornamental characteristics, and have fruits that contain high fat content for animals. Also, they are an important understory tree in natural forests. Dogwood anthracnose, caused by ...

Reward modulation of contextual cueing: Repeated context overshadows repeated target location

Contextual cueing can be enhanced by reward. However, there is a debate if reward is associated with the repeated target–distractor configurations or with the repeated target locations that occur in both repeated and new displays. Based on neuroimaging evidence, we hypothesized that reward becomes associated with the target location only in new displays, but not in repeated ...

Mining of high utility-probability sequential patterns from uncertain databases

High-utility sequential pattern mining (HUSPM) has become an important issue in the field of data mining. Several HUSPM algorithms have been designed to mine high-utility sequential patterns (HUPSPs). They have been applied in several real-life situations such as for consumer behavior analysis and event detection in sensor networks. Nonetheless, most studies on HUSPM have focused ...

What do we really know about corporate hedging? A meta-analytical study

This paper employs meta-analysis to aggregate and systematically analyze the mixed empirical evidence on the determinants of corporate hedging reported in 132 previously published studies covering data from more than 73,000 firms. Among the fourteen proxy variables analyzed by multivariate meta-analysis, three variables emerge as reliable explanatory factors for corporate hedging ...

A Bayesian spatio-temporal model for forecasting Anaplasma species seroprevalence in domestic dogs within the contiguous United States

This paper forecasts the 2016 canine Anaplasma spp. seroprevalence in the United States from eight climate, geographic and societal factors. The forecast’s construction and an assessment of its performance are described. The forecast is based on a spatial-temporal conditional autoregressive model fitted to over 11 million Anaplasma spp. seroprevalence test results for dogs ...

Neurosurgeon academic impact is associated with clinical outcomes after clipping of ruptured intracranial aneurysms

Background Surgeon-dependent factors such as experience and volume are associated with patient outcomes. However, it is unknown whether a surgeon’s research productivity could be related to outcomes. The main aim of this study is to investigate the association between the surgeon’s academic productivity and clinical outcomes following neurosurgical clipping of ruptured aneurysms. ...

Is de ‘surprise question’ een goede screeningstool om palliatieve patiënten te identificeren?

‘Zou u verrast zijn mocht uw patiënt in de komende 6 tot 12 maanden overlijden?’ Deze surprise question werd meer dan tien jaar geleden ontwikkeld en wereldwijd gebruikt om patiënten te identificeren met een verhoogde palliatieve zorgnood.

A microscopic simulation model for pedestrian-pedestrian and pedestrian-vehicle interactions at crosswalks

This study aims to develop a microscopic pedestrian behavior model considering various interactions on pedestrian dynamics at crosswalks. Particularly, we take into account the evasion behavior with counter-flow pedestrians, the following behavior with leader pedestrians, and the collision avoidance behavior with vehicles. Aerial video data at one intersection in Beijing, China are ...

A specialist peer mentoring program for university students on the autism spectrum: A pilot study

Introduction The provision of peer mentoring may improve tertiary education outcomes of students with autism spectrum disorder (ASD). This study evaluated the pilot year of the Curtin Specialist Mentoring Program (CSMP), a specialised peer mentoring program for university students with ASD aimed at improving self-reported well-being, academic success and retention in university ...

Protective effect of zinc preconditioning against renal ischemia reperfusion injury is dose dependent

Objectives Ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury and chronic kidney disease. Two promising preconditioning methods for the kidney, intermittent arterial clamping (IC) and treatment with the hypoxia mimetic cobalt chloride, have never been directly compared. Furthermore, the protective efficacy of the chemically related transition metal Zn2+ ...

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

Objective To compare three groupings of Electronic Health Record (EHR) billing codes for their ability to represent clinically meaningful phenotypes and to replicate known genetic associations. The three tested coding systems were the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes, the Agency for Healthcare Research and Quality ...

Detecting Surface Changes from an Underground Explosion in Granite Using Unmanned Aerial System Photogrammetry

Efficient detection and high-fidelity quantification of surface changes resulting from underground activities are important national and global security efforts. In this investigation, a team performed field-based topographic characterization by gathering high-quality photographs at very low altitudes from an unmanned aerial system (UAS)-borne camera platform. The data collection ...

The oral bacterial microbiome of occlusal surfaces in children and its association with diet and caries

Dental caries is the most prevalent disease in humans globally. Efforts to control it have been invigorated by an increasing knowledge of the oral microbiome composition. This study aimed to evaluate the bacterial diversity in occlusal biofilms and its relationship with clinical surface diagnosis and dietary habits. Anamneses were recorded from thirteen 12-year-old children. ...

A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice

Background Obesity frequently associates with the development of non-alcoholic fatty liver disease (NAFLD) and atherosclerosis. Chronic inflammation in white adipose tissue (WAT) seems to be an important driver of these manifestations. Objective This study investigated a combination of an extensively hydrolyzed casein (eHC), docosahexaenoic acid (DHA), arachidonic acid (ARA), and ...

Dr.seq2: A quality control and analysis pipeline for parallel single cell transcriptome and epigenome data

An increasing number of single cell transcriptome and epigenome technologies, including single cell ATAC-seq (scATAC-seq), have been recently developed as powerful tools to analyze the features of many individual cells simultaneously. However, the methods and software were designed for one certain data type and only for single cell transcriptome data. A systematic approach for ...

Comprehensive identification of age-related lipidome changes in rat amygdala during normal aging

Brain lipids are integral components of brain structure and function. However, only recent advancements of chromatographic techniques together with mass spectrometry allow comprehensive identification of lipid species in complex brain tissue. Lipid composition varies between the individual areas and the majority of previous reports was focusing on individual lipids rather than a ...

Caustic free completion of pressureless perfect fluid and k-essence

Both k-essence and the pressureless perfect fluid develop caustic singularities at finite time. We further explore the connection between the two and show that they belong to the same class of models, which admits the caustic free completion by means of the canonical complex scalar field. Specifically, the free massive/self-interacting complex scalar reproduces dynamics of ...

Reclaiming streets for outdoor play: A process and impact evaluation of “Juega en tu Barrio” (Play in your Neighborhood), an intervention to increase physical activity and opportunities for play

Background New strategies are required to create supportive physical and social environments for children and promote active free-play. Juega en tu Barrio (JETB; Play in your Neighborhood) was designed and implemented to explore the effectiveness of closing a street in a low-to-middle income neighborhood in order to increase children’s outside play and physical activity. Methods A ...

Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) by the environmental pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) affects both oral tolerance and food ...

The Effects of the Structure and Composition of the Hydrophobic Parts of Phosphatidylcholine-Containing Systems on Phosphatidylcholine Oxidation by Ozone

The degree of lipid unsaturation is a parameter used to describe membrane susceptibility to oxidation. This paper highlights the importance of double bond distribution in the hydrophobic parts of lipid layers. The problem was studied by determining the effects induced by ozone dissolved in an aqueous phase acting on layers of unsaturated cholines of various molecular structures, ...

Intratumoural production of TNFα by bacteria mediates cancer therapy

Systemic administration of the highly potent anticancer therapeutic, tumour necrosis factor alpha (TNFα) induces high levels of toxicity and is responsible for serious side effects. Consequently, tumour targeting is required in order to confine this toxicity within the locality of the tumour. Bacteria have a natural capacity to grow within tumours and deliver therapeutic molecules ...

Existence of periodic solutions for some quasilinear parabolic problems with variable exponents

In this paper, we prove the existence of at least one periodic solution for some nonlinear parabolic boundary value problems associated with Leray–Lions’s operators with variable exponents under the hypothesis of existence of well-ordered sub- and supersolutions.

Affective and cognitive behavior in the alpha-galactosidase A deficient mouse model of Fabry disease

Fabry disease is an X-linked inherited lysosomal storage disorder with intracellular accumulation of globotriaosylceramide (Gb3) due to α-galactosidase A (α-Gal A) deficiency. Fabry patients frequently report of anxiety, depression, and impaired cognitive function. We characterized affective and cognitive phenotype of male mice with α-Gal A deficiency (Fabry KO) and compared ...

Isolation and characterization of GmMYBJ3, an R2R3-MYB transcription factor that affects isoflavonoids biosynthesis in soybean

Isoflavonoids are secondary metabolites that play a variety of roles in plant-microbe interactions and plant defenses against abiotic stresses. Here we report a new MYB transcription factor (TF) gene, GmMYBJ3, that is involved in the isoflavonoids biosynthesis. The GmMYBJ3 gene is 1,002 bp long and encodes a protein of 333 amino acids. Amino acid sequence analysis showed that ...

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