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Changes in Parahippocampal White Matter Integrity in Amnestic Mild Cognitive Impairment: A Diffusion Tensor Imaging Study

In the present study, changes in the parahippocampal white matter (PWM), in the region that includes the perforant path, were investigated, in vivo, in 14 individuals with amnestic mild cognitive impairment (aMCI) compared to 14 elderly controls with no cognitive impairment (NCI). For this purpose, (1) volumetry; (2) diffusion tensor imaging (DTI) derived measures of mean...

Realization problem for positive linear systems with time delay

The realization problem for positive single-input single-output discrete-time systems with one time delay is formulated and solved. Necessary and sufficient conditions for the solvability of the realization problem are established. A procedure for computation of a minimal positive realization of a proper rational function is presented and illustrated by an example.

Hinterlassen SSRI Spuren im Gehirn von Babys?

Ob bei Kindern, die im Mutterleib Antidepressiva ausgesetzt waren, Entwicklungsstörungen auftreten, ist bislang unklar. Ein gewisser Einfluss auf die Hirnentwicklung wäre jedoch plausibel, da Serotonin und Serotonintransporter an vielen Entwicklungsschritten im Gehirn beteiligt sind. Forscher aus den USA haben den Einfluss von SSRI auf die Entwicklung von Neugeborenen genauer...

Degenerative Jargon Aphasia: Unusual Progression of Logopenic/Phonological Progressive Aphasia?

Primary progressive aphasia (PPA) corresponds to the gradual degeneration of language which can occur as nonfluent/agrammatic PPA, semantic variant PPA or logopenic variant PPA. We describe the clinical evolution of a patient with PPA presenting jargon aphasia as a late feature. At the onset of the disease (ten years ago) the patient showed anomia and executive deficits, followed...

Modifying Olympics Medal Table via a Stochastic Multicriteria Acceptability Analysis

This paper addresses the issue of developing a widely accepted Olympics ranking scheme based upon the Olympic Game medal table published by the International Olympic Committee, since the existing lexicographic ranking and sum ranking systems are both criticized as biases. More specifically, the lexicographic ranking system is deemed as overvaluing gold medals, while the sum...

Risk factors of preterm birth among mothers who gave birth in public hospitals of central zone, Tigray, Ethiopia: unmatched case–control study 2017/2018

ObjectiveThe aim of the study was to identify the risk factors for preterm birth in public hospitals of the central zone, Tigray, Ethiopia 2017/2018.ResultA total of 88 neonates who born preterm (cases) and 176 neonates who born term (controls) with their index mothers were included making a response rate of 100%. About 84/88 (95.5%) mothers in cases and 173/176 (98.3%) in...

Update: Efficacy of Military Fluid Intake Guidance

Fluid intake during military training is prescribed based on the interactions among work rates, environmental conditions, and uniform configurations. The efficacy of this guidance has not been empirically assessed in over a decade. To determine the acceptability of the fluid intake guidance, sweat losses were measured in a variety of conditions with modern uniform/body armor...

Effective advocacy strategies for influencing government nutrition policy: a conceptual model

Influencing public policy change can be difficult and complex, particularly for those with limited power and resources. For any one issue there may be several groups, including the commercial sector and public health advocates advocating from different policy perspectives. However, much of the public health advocacy literature and tools available for those wanting to improve...

Unrecognized myocardial infarction detected on cardiac magnetic resonance imaging: Association with coronary artery calcium score and cardiovascular risk prediction scores in asymptomatic Asian cohort

Background To investigate the association between unrecognized myocardial infarction (UMI) assessed with cardiac magnetic resonance (CMR) and coronary artery calcium (CAC) and cardiovascular risk prediction scores in asymptomatic Asian subjects. Materials and methods Total 872 asymptomatic subjects without prior cardiovascular event (male:female, 817:55; age, 53.88 ± 5.91) who...

Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for clinical use and genetic discovery efforts in human disease

Many neurodegenerative diseases are caused by nucleotide repeat expansions, but most expansions, like the C9orf72 ‘GGGGCC’ (G4C2) repeat that causes approximately 5–7% of all amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) cases, are too long to sequence using short-read sequencing technologies. It is unclear whether long-read sequencing technologies can...

Evaluation and Management of Skeletal Health in Celiac Disease: Position Statement

OBJECTIVE: To review the evaluation and management of skeletal health in patients with celiac disease (CD), and to make recommendations on screening, diagnosis, treatment and follow-up of low bone mineral density (BMD) in CD patients.

On dynamic coloring of certain cycle-related graphs

Coloring the vertices of a particular graph has often been motivated by its utility to various applied fields and its mathematical interest. A dynamic coloring of a graph G is a proper coloring of the vertex set V(G) such that for each vertex of degree at least 2, its neighbors receive at least two distinct colors. A dynamic k-coloring of a graph is a dynamic coloring with k...

Effects of single-point acupuncture (HT7) in the prevention of test anxiety: Results of a RCT

Background The number of students using neuro enhancement to improve their performance and to prevent test anxiety is increasing. The acupuncture point Heart 7 (HT7) has been described as being prominent in reducing states of anxiety. Methods We conducted a randomized placebo-controlled, two-armed pilot trial to investigate the efficacy of a single-point acupuncture treatment at...

On the Investigation of State Space Reconstruction of Nonlinear Aeroelastic Response Time Series

Stall-induced aeroelastic motion may present severe non-linear behavior. Mathematical models for predicting such phenomena are still not available for practical applications and they are not enough reliable to capture physical effects. Experimental data can provide suitable information to help the understanding of typical non-linear aeroelastic phenomena. Dynamic systems...

Bioactive Constituents of Brazilian Red Propolis

In a new propolis type, red Brazilian propolis, 14 compounds were identified (six of them new for propolis), among them simple phenolics, triterepenoids, isoflavonoids, prenylated benzophenones and a naphthoquinone epoxide (isolated for the first time from a natural source). Three of the major components demonstrated significant antimicrobial activity, and two (obtained as...

Spontaneous Expression of Interleukin-2 In Vivo in Specific Tissues of Young Mice

In situ hybridization and immunohistochemistry were used to determine the spectrum of tissues in which interleukin-2 (IL-2) mRNA and protein are found in healthy, normal young mice. In neonatal animals, IL-2 is expressed specifically by distinct, isolated cells at three major sites: the thymus, skin, and gut. Based on morphology and distribution, the IL-2-expressing cells...

Minor Immunoreactivity in GDNF-, BDNF-, or NT-3-Treated Substantia Nigra Allografts

Glial-cell-line-derived neurotrophic factor (GDNF) stimulates the survival of dopaminergic neurons. Little is known, however, about the possible immune sequelae of GDNF exposure or of exposure to other putative trophic factors. To address these questions, pieces of mesencephalic tissue, substantia nigra, from 15-day-old donor embryos were transplanted into the anterior chamber of...

Studies on removal of arsenic using cellulose acetate–zinc oxide nanoparticle mixed matrix membrane

Mixed matrix membranes prepared by varying compositions of Cellulose acetate, acetone and formamide for the synthesis of ultrafiltration/nanofiltration membranes with and without nanoparticles for the removal of arsenic from synthetic solution. Zinc oxide nanoparticles were synthesized by an in situ ultrasonic technique and characterization done using XRD and SEM. In the current...

Which processes are behind the relationship between species abundance and environmental suitability? Monte Albo cave salamander as model species

Species can show a strong variation of local abundance across their ranges. Recent analyses suggested that variation in abundance can be related to environmental suitability, as the highest abundances are often observed in populations living in the most suitable areas. However, there is limited information on the mechanisms through which variation in environmental suitability...

SecurAcath for Securing Peripherally Inserted Central Catheters: A NICE Medical Technology Guidance

Central venous catheters are commonly used to deliver therapies and to monitor patients, and require securing at the point of percutaneous entry to avoid dislodgement. SecurAcath is a catheter securement device designed for central venous catheters. The National Institute for Health and Care Excellence, as a part of its Medical Technologies Evaluation Programme, selected this...

Effect of Various Additives on Photocatalytic Degradation of 4-Nitrophenol

The photocatalytic degradation of 4-nitrophenol (4-NP) assisted by titanium dioxide (TiO2) was investigated in aqueous suspension under irradiation by UV light. The effect of different supporting materials mixed physically with TiO2on the photocatalytic degradation of 4-NP has been studied. TiO2 with all supports exhibits good degradation efficiency of 4-NP and was better than...

Diflexx Duo Compared to Capreno, Halex GT, Armezon, Outlook, Status, Degree Xtra, and Bicep II Magnum for Weed Control in Irrigated Corn

Control of kochia, quinoa, and green foxtail was complete with all herbicides at 78 days after treatment (DAT). Palmer amaranth, common sunflower, and crabgrass was 97% at 8 DAT. By 78 DAT, common sunflower control was complete with all herbicides. Crabgrass control at 78 DAT was excellent except when Diflexx Duo (dicamba + tembotrione) at 24 oz/a + atrazine was mixed with...

Today I'm a Veterinarian

Today I'm a Veterinarian is one of a series of books that details interesting careers. Young readers can learn about different occupations as they are entertained and entranced by the colorful illustrations and bright, cheerful pictures. In this particular book, Dr. Emma is a veterinarian who is sharing a little bit about what she does at work every day. One unique thing about...

The role of properdin in complement-mediated renal diseases: a new player in complement-inhibiting therapy?

Properdin is known as the only positive regulator of the complement system. Properdin promotes the activity of this defense system by stabilizing its key enzymatic complexes: the complement alternative pathway (AP) convertases. Besides, some studies have indicated a role for properdin as an initiator of complement activity. Though the AP is a powerful activation route of the...

Design and Implementation of a Low Power Ternary Full Adder

In this work, the design and implementation of a low power ternary full adder are presented in CMOS technology. In a ternary full adder design, the basic building blocks, the positive ternary inverter (PTI) and negative ternary inverter (NTI) are developed using a CMOS inverter and pass transistors. In designs of PTI and NTI, W/L ratios of transistors have been varied for their...

LASIE: Large Area Spectroscopic Imaging Ellipsometry for Characterizing Multi-Layered Film Structures

In this investigation, we describe a spectroscopic imaging ellipsometry for large area measurements, named as large area spectroscopic ellipsometry (LASIE). LASIE uses a broadband light source and an imaging spectrometer in order to obtain the spectral-spatial intensity images corresponding to a measurement line of a specimen and it can characterize the 3D multi-film structures...

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