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Combination Therapy with Dipyridamole and Clopidogrel for Secondary Stroke Prevention in Aspirin-Intolerant Patients After Myocardial Infarction: Results of a Nationwide Case-Control Study

Background and PurposeCombination therapy with dipyridamole and clopidogrel in stroke prevention and long-term outcomes in aspirin-intolerant patients with acute myocardial infarction (AMI) and previous stroke are unknown. This nationwide study analyzed the impact of dipyridamole and clopidogrel on secondary stroke prevention and long-term outcomes in aspirin-intolerant stroke...

Changes in soil organic carbon contents and fractionations of forests along a climatic gradient in China

BackgroundSoil organic carbon (SOC) is a large reservoir of terrestrial carbon (C); it consists of different fractions of varying complexity and stability. Partitioning SOC into different pools of decomposability help better predict the trend of changes in SOC dynamics under climate change. Information on how physical fractions and chemical structures of SOC are related to...

Pharmacological Treatments for Disordered Gambling: A Meta-analysis

Disordered gambling is a public health concern associated with detrimental consequences for affected individuals and social costs. Currently, opioid antagonists are considered the first-line treatments to reduce symptoms of uncontrolled gambling. Only recently, glutamatergic agents and combined pharmacological and psychological treatments have been examined appearing promising...

Background gravity correction to the limiting mass of white dwarfs

While computing the Fermi degeneracy pressure of electrons in a white dwarf star within the framework of hydrostatic equilibrium, we depart from the extant practice of treating the electrons as a free fermion gas, by including the effect of the background gravitational potential experienced by the electrons in the star, resulting from the mass of its constituent atoms (being the...

Abiotic conditions governing the myceliogenic germination of Sclerotinia sclerotiorum allowing the basal infection of Brassica napus

Sclerotinia sclerotiorum is the causal pathogen of sclerotinia stem rot (SSR) in canola, causing significant yield losses in this crop globally, when conditions are favourable. The pathogen can cause disease symptoms on canola through ascospore infection from carpogenically germinated sclerotia or by basal infection from myceliogenically germinated sclerotia. While infection...

Direct Growth of Single Crystalline GaN Nanowires on Indium Tin Oxide-Coated Silica

In this work, we demonstrated the direct growth of GaN nanowires on indium tin oxide (ITO)-coated fused silica substrate. The nanowires were grown catalyst-free using plasma-assisted molecular beam epitaxy (PA-MBE). The effect of growth condition on the morphology and quality of the nanowires is systematically investigated. Structural characterization indicates that the nanowires...

Feststoffmanagement bei Wasserkraftanlagen in Österreich

Hydropower inevitably changes the sediment balance due to natural and physical relations. The change, however, can be reduced by constructive measures in power plant design as well as by an operational management that is adapted to the natural conditions. Therefore, for many hydropower plants the need for sediment management measures, such as reservoir flushing and compensational...

Internationale Aktivitäten in Zusammenhang mit Sedimentforschung und -management auf globaler, europäischer, regionaler und Einzugsgebietsebene

Sediment surplus and deficit following the interruption of sediment continuity, the increase of the transport capacity due to river regulation leading to a reduction of the river bed width, an increase of bed slope and prohibition of side erosion and bed form development as well as cutting off floodplains are growing in almost all river basins. Land use change and climate change...

Research on denoising processing of computer video electromagnetic leakage reduction image based on fuzzy degree

On the basis of analyzing, receiving, and parsing the computer video electromagnetic leakage emission signal, an image of the screen display content can be obtained. Due to the interference noise existing in the receiving process, the received image information may be drifted, the recognition may be poor, and the definition might be low. In order to improve the recognizability of...

Atypical ductal hyperplasia and the risk of underestimation: tissue sampling method, multifocality, and associated calcification significantly influence the diagnostic upgrade rate based on subsequent surgical specimens

BackgroundRisk assessment and therapeutic options are challenges when counselling patients with an atypical ductal hyperplasia (ADH) to undergo either open surgery or follow-up only.MethodsWe retrospectively analyzed a series of ADH lesions and assessed whether the morphological parameters of the biopsy materials indicated whether the patient should undergo surgery. A total of...

The effect of antiretroviral treatment on selected genes in whole blood from HIV-infected adults sensitised by Mycobacterium tuberculosis

HIV-1 co-infection is a leading cause of susceptibility to tuberculosis (TB), with the risk of TB being increased at all stages of HIV-1 infection. Antiretroviral treatment (ART) is the most effective way to reduce the risk of TB in HIV-1 co-infected people. Studying protective, ART-induced, immune restoration in HIV-1 infected individuals sensitised by Mycobacterium tuberculosis...

Korrekt abrechnen bei Patienten aus dem Ausland

Die Abrechnung bei Patienten aus dem Ausland ist nicht ganz einfach, weil je nach Herkunftsland andere Regeln gelten. Die KBV hat ihre entsprechende Checkliste zum 1. Oktober aktualisiert, um Ärzten einen Leitfaden an die Hand zu geben.

Pseudoesotropia in Chinese Children: A Triphasic Development of the Interepicanthal Folds Distance-to-Interpupillary Distance Ratio and Its Changing Perception

PurposeTo delineate the development of the interepicanthal fold distance (IEFD) to interpupillary distance (IPD) in Chinese children, and to quantify how their ratio (EFDPD ratio) affects parent’s judgment on whether a child’s two eyes appear misaligned.MethodsThe values of IPD and IEFD were measured in 750 children, aged between 3 and 17 years. The developmental trend of EFDPD...

Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway

Deguelin induces apoptosis in colorectal cancer cells by activating the p38 MAPK pathway Liubo Chen,1,2,* Kai Jiang,1,2,* Haiyan Chen,1,3,* Yang Tang,1,2 Xinyi Zhou,1,2 Yinuo Tan,1,4 Ying Yuan,1,4 Qian Xiao,1,2 Kefeng Ding1,2 1Cancer Institute (Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Key Laboratory of Molecular Biology in...

Meat consumption, behaviour and the media environment: a focus group analysis across four countries

The livestock sector is a major driver of climate change, accounting for 14.5% of anthropogenic greenhouse gas emissions. Population growth and rising prosperity are expected to see global consumption of meat rise by 76% by mid-century, a rate which is associated with significant social and environmental costs. There is therefore a compelling case for public measures to promote...

A novel Bayesian approach for latent variable modeling from mixed data with missing values

We consider the problem of learning parameters of latent variable models from mixed (continuous and ordinal) data with missing values. We propose a novel Bayesian Gaussian copula factor (BGCF) approach that is proven to be consistent when the data are missing completely at random (MCAR) and that is empirically quite robust when the data are missing at random, a less restrictive...

Holographic aspects of a higher curvature massive gravity

We study the holographic dual of a massive gravity with Gauss–Bonnet and cubic quasi-topological higher curvature terms. Firstly, we find the energy–momentum two point function of the 4-dimensional boundary theory where the massive term breaks the conformal symmetry as expected. An a-theorem is introduced based on the null energy condition. Then we focus on a black brane solution...

Schlechte Ernährung hat tödliche Folgen

Deutschland belegt bei den ernährungsbedingten kardiovaskulären Sterbefällen einen Spitzenplatz in Westeuropa. Nur Griechen und Finnen schaden sich durch ungesundes Essen noch mehr, legt eine WHO-Studie nahe.

Oil nanoencapsulation: development, application, and incorporation into the food market

Oils are very important substances in human nutrition. However, they are sensitive to oxygen, heat, moisture, and light. In recent years, there has been a growing interest in the modification technology of oils. Methods that modify oil characteristics and make oils suitable applications have been increasingly studied. Nanotechnology has become one of the most promising studied...

A Holistic Teaching Approach for Your Qualitative Research Class: A Book Review

A book review on Teaching Qualitative Research: Strategies for engaging emerging scholars, written by Raji Swaminathan and Thalia M. Mulvihill, published in 2018. This review offers an overall look into an instructor’s book by highlighting its unique features for teaching qualitative research in the social sciences. The review presents the main intent of the book, which is the...

Tolerability of Topical Treatments for Atopic Dermatitis

Atopic dermatitis (AD) is a common inflammatory skin disease that is accompanied by increased sensitivity to itch-provoking and pain-provoking stimuli. Patients with AD experience skin pain before initiation of therapy and have also reported painful application site reactions in clinical trials of emollients and prescription topical therapies, including topical corticosteroids...

Das „Lübecker Modell Bewegungswelten“ – Multidimensionale Prävention in stationären Pflegeeinrichtungen durch ein bewegungsförderndes Programm

In inpatient care there is a need for prevention and health promotion offers that are specific to the target group. In the course of implementing the Prevention Act, those interventions should be chosen for sustainable implementation that are conceptually sound, standardized, workable, low-threshold, and demonstrably effective.The “Lübeck Worlds of Movement Model” is a physically...

Lepidoptera of Canada

The known Lepidoptera (moths and butterflies) of the provinces and territories of Canada are summarised, and current knowledge is compared to the state of knowledge in 1979. A total of 5405 species are known to occur in Canada in 81 families, and a further 50 species have been reported but are unconfirmed. This represents an increase of 1348 species since 1979. The DNA barcodes...

Traffic prediction using a self-adjusted evolutionary neural network

Short-term prediction of traffic flow is one of the most essential elements of all proactive traffic control systems. The aim of this paper is to provide a model based on neural networks (NNs) for multi-step-ahead traffic prediction. NNs’ dependency on parameter setting is the major challenge in using them as a predictor. Given the fact that the best combination of NN parameters...

A peek into the origin of creep in sand

This paper presents the results of an experimental study of the particle scale mechanisms that underpin creep, on-going deformations under constant external load, in dry non-cemented sand under 1D oedometric compression loading at 2500 kPa. Traditional observations on the boundary of the sample are complemented with simultaneous measurements of the 3D kinematics of both the...

Minimization of the Wilson’s Central Terminal voltage potential via a genetic algorithm

ObjectiveThe Wilson Central Terminal (WCT) is an artificially constructed reference for surface electrocardiography, which is assumed to be near zero and steady during the cardiac cycle; namely it is the simple average of the three recorded limbs (right arm, left arm and left leg) composing the Einthoven triangle and considered to be electrically equidistant from the electrical...

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