Proceedings in Obstetrics and Gynecology

http://ir.uiowa.edu/pog

List of Papers (Total 307)

A predictive model for serous epithelial ovarian cancer chemo-response using clinical characteristics

One of the prognostic factors most highly associated with ovarian cancer survival is response to initial chemotherapy. Current prediction models of chemo-response built with comprehensive molecular datasets, like The Cancer Genome Atlas (TCGA), could be improved by including clinical and outcomes data designed to study response to treatment. The objective of this study was to...

Impact of vasopressin receptors on regulation of immune response in preeclampsia

Preeclampsia is a common disorder of pregnancy resulting in increased blood pressure and end organ effects. The pathogenesis of preeclampsia is multi-factorial. Arginine vasopressin (AVP) is increased in preeclampsia, and the chronic infusion of AVP throughout gestation has previously been shown to be sufficient to produce a phenotype of preeclampsia in C57BL/6J mice...

Single incision laparo-endoscopic surgery (SILS) is comparable with robotic surgery at a tertiary care center for the management of gynecologic oncology patients

A shift toward minimally invasive surgical techniques has been implemented in the surgical management of gynecologic oncology patients. Over the course of 18 months, we have established a single incision laparo-endoscopic surgery program (SILS), and incorporated it in the management of our patients. We sought to assess the operative and postoperative outcomes of these patients in...

A rare case of lethal campomelic dysplasia

Campomelic dysplasia is a rare and mostly lethal congenital malformation. It is known as an autosomal dominant disorder due to mutations in SOX9, a member of the SOX (SRY-related HMG box) gene family. Here we report a case of a 26 years old primigravida married for 3 years with a history of consanguinity. She was impregnated by intracytoplasmic sperm injection (ICSI) due to male...

Management of pregnancy in patients with exstrophy-epispadias sequence: a case series and literature review

Exstrophy-epispadias sequence is an uncommon diagnosis in which surgical reconstruction has increased quality of life for these patients. As they are entering the reproductive phase of their life, consideration must be made for management of their pregnancies in the context of their genitourinary reconstruction. There have been few case reports of patients with cloacal exstrophy...

Preoperative evaluation of patients with ovarian masses using the risk of malignancy index 4 model

Objective: To evaluate the performance of the RMI 4 in discriminating benign from malignant ovarian masses. Study Design: Cross-sectional study. Setting: Assiut Women Health Hospital- Egypt. Materials and methods: This was an observational cross-sectional study involving 91 patients at Women's Health Hospital, Assiut University, Egypt during the period between January, 2016 and...

A review of medical and surgical techniques for overcoming cervical stenosis

Cervical stenosis is anomalous narrowing or obstruction of any part or the entirety of the cervical canal. It may be congenital or acquired as the result of aging, nulliparity, use of progestins, curettage, cervical surgery or any combination of these factors. Cervical stenosis is challenging to gynecologists in that it presents an additional complication to the completion of...

A rare case of giant dermoid cyst with ipsilateral paratubal cystadenoma during pregnancy

Dermoid cysts are considered the most common ovarian cysts in adolescents and pregnant women. In rare cases, they can attain a huge size. Paratubal cysts are also common in adolescents. They are usually simple cysts present in the broad ligament. In this case, we report a giant dermoid cyst with ipsilateral paratubal serous cystadenoma discovered during pregnancy of a 20-year-old...

Uncommon case of hydrosalpinx-induced adnexal torsion in a postmenopausal woman

Adnexal torsion is a twisting of the adnexa, including the ovary and/or the fallopian tube, around its own vascular axis. Most cases of adnexal torsion occur in women of reproductive age and only rarely in postmenopausal women. Here, we report a case of 58-year-old woman, postmenopausal for 6 years, who presented with acute lower abdominal pain. Ultrasound scan showed a right...

Management of vaginal wall perforation during a second trimester dilation and evacuation

Background: We report an unusual case involving vaginal perforation associated with second trimester dilation and evacuation. Review of the literature fails to identify additional reports. Case: A 22 year G3P1011 female at 16 weeks gestation referred for evaluation following incomplete dilation and evacuation was found to have vaginal perforation, and communication with the...

True knot of the umbilical cord in advanced weeks of pregnancy: a case report

True knot of the umbilical cord is a very rare condition. Usually a true knot is noticed after delivery and does not lead to problems. It is relatively less common than the other umbilical cord anomalies. Most authors agree that there is little that can be done to prevent fetal death in undiagnosed true knot. In our case, the patient gave birth to a healthy male baby weighing...

A rare case of posterior uterine rupture with neonatal survival during trial of vaginal birth after cesarean section

Posterior wall uterine rupture is a rare complication. Trial of vaginal birth after cesarean section (CS) is a predisposing factor especially when associated with augmentation of labor. Here we report a case of intrapartum uterine rupture during the second stage of labor in a multiparous woman trying vaginal birth after previous CS. Emergency laparotomy was done and the baby was...

Small bowel obstruction: a recurrence of melanoma during the second trimester of pregnancy

Background: The incidence of melanoma is on the rise in the United States and is particularly prevalent among women of childbearing age. Obtaining a complete history and understanding the unpredictable behavior of melanoma is essential to make the diagnosis of recurrent disease during pregnancy. Case: A 35-year-old G2P1 at 23 weeks and 1 days’ gestation with a remote history of...

Recurrent spontaneous third-trimester uterine rupture after hysteroscopic resection of myoma: a case report

Uterine rupture is a catastrophic obstetrical emergency with serious effects on both women and fetuses. Operative hysteroscopic procedures can add more risk factor for occurrence of this tragedy. Here, we report a case of spontaneous recurrent rupture uterus at 33 weeks of gestation in a 32 years old woman with previous history of hysteroscopic resection of submucous myoma after...

Traumatic vulvar aphthous ulcers: a case series

We present three women who each presented with a vulvar ulcer consistent with aphthous. In each case a biopsy was performed which excluded malignancy and revealed non-specific findings. All women responded following intralesional steroid injections. We initially considered a diagnosis of pyoderma gangrenosum. However, the presentation and clinical findings were more consistent...

The maternal and neonatal outcomes of teenage pregnancy in a tertiary university hospital in Egypt

Aim: To highlight the grave complications among teenage mothers in Assiut Woman's Health Hospital compared with the adult mothers. Methods: This study was a prospective case control study, conducted at the Labor Ward of Assiut Woman's Health Hospital from 1st of January 2016 to 30th of June 2016. We included teenage pregnant women (13-19 completed years at delivery) as case and...

Full term delivery of a Harlequin ichthyosis baby: a case report

Harlequin ichthyosis (HI) is one of the most severe and rare autosomal recessive congenital ichthyosis (ARCI), characterized by severe hyperkeratosis, extensive fissuring and a variable degree of cutaneous malformations. Here we report a case of 22 years old female patient in her first pregnancy. The baby was born at 39 weeks of gestation from non-consanguineous parents. At birth...

Tubal splenosis: unusual location of the spleen

İntroduction: Splenosis is defined as the autotransplantation of splenic tissue to abnormal locations after splenic injury. Heterotopic spleen can be found within the abdominal and pelvic cavities. We report a tubal splenosis case in a 48 year old woman who underwent splenectomy following a blunt trauma 41 years prior to presentation. Case report: A 48 years old gravida 3, para 3...

Herniated gravid uterus through an infra-umbilical laparotomy scar: a case report

Herniation of a gravid uterus through the abdominal wall is a rare and potentially serious condition due to its antecedent complications. Management is determined by gestational age. Simultaneous hernioplasty with cesarean section is considered safe. Clinical awareness of this complication will prevent delay in its diagnosis and treatment. Delay in recognition of this condition...

Recurrent second-trimester intrauterine fetal death due to undiagnosed atrioventricular block: A case report

Fetal cardiac abnormalities are one of the common causes of non-immune fetal hydrops. Early diagnosis and treatment may prevent the late consequences that can occur as heart failure and intrauterine fetal death. Herein we report the case of a 32-year-old patient with a history of recurrent second trimester intrauterine fetal death. She presented with fetal hydrops at 23 weeks. A...

Metastatic squamous cell carcinoma to the colon arising from a mature cystic ovarian teratoma

Malignant transformation of a mature cystic teratoma is extremely rare, occurring in 0.17-2% of cases.1 The most common malignant degeneration is squamous cell carcinoma (SCC) arising from the ectoderm. Approximately half of all cases of SCC of the ovary are confined to the ovary at time diagnosis.1,2 Secondary to its absolute rarity and the relative infrequency of cases with...

Spontaneous triplet pregnancy with twin fetuses papyraeci: a rare case report and review of the literature

A fetal death in a multiple pregnancy with one or more normally surviving fetus is unusual. Fetus papyraceous (FP) is a rare obstetric complication in multiple gestations. It is defined as retention of a mummified parchment like remains of a dead fetus in multiple pregnancy associated with a viable twin. It is important to reassure the patient of the normal outcome expected in...

Management of preeclampsia after heart transplant

We present a 20-year-old primiparous patient status post heart transplant at 6 months with long-standing hypertension progressing to super-imposed preeclampsia. Pregnancy and delivery after thoracic transplantation is no longer a rare occurrence, however, these women are at a greater risk of gestational hypertension and preeclampsia.1 Current literature does not provide treatment...

Effects of irregular antenatal care attendance in primiparas on the perinatal outcomes: a cross sectional study

Aim: Antenatal care (ANC) is a key strategy for reducing maternal and neonatal morbidity and mortality rates because adequate utilization of antenatal health care services is associated with improved maternal and neonatal health outcomes. The current study aims to identify the factors causing lack of regular attendance at ANC clinics in primiparas and to determine the effects of...