Clinical Infectious Diseases

List of Papers (Total 5,112)

Influence of Ciprofloxacin Resistance on Risk Factors for Endovascular Infection in Patients with Infection Due to Group C Nontyphoid Salmonellae

From January 2000 through September 2004, a total of 54 patients with infection due to group C nontyphoid salmonellae were evaluated; 8 patients had gastroenteritis alone, and 46 patients had bacteremia. of the 46 patients who had bacteremia, 12 had endovascular infection and 34 did not. The number of infections due to ciprofloxacin-resistant Salmonella organisms is increasing...

Analysis of Chemokine and Cytokine Expression in Patients with HIV and GB Virus Type C Coinfection

Background. Plasma levels of several chemokines and cytokines were evaluated in a cohort of 161 human immunodeficiency virus (HIV)-positive patients to shed light on a clinically relevant mechanism that would explain the putative beneficial effect of GB virus type C (GBV-C) coinfection.

Risk Factors for Increasing Multidrug Resistance among Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella Species

Background. The importance of infections due to extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) has been increasingly recognized in recent years. ESBL-EK infections are of clinical concern, because few antimicrobials are available as therapeutic options. Increased reliance on carbapenems has led to increasing carbapenem resistance...

Factors Influencing the Effectiveness of Oseltamivir and Amantadine for the Treatment of Influenza: A Multicenter Study from Japan of the 2002—2003 Influenza Season

Background. To evaluate the effectiveness of oseltamivir and amantadine for the treatment of influenza with respect to various clinical factors, a prospective multicenter study of the influenza season of 2002–2003 was done with 2163 patients whose condition was diagnosed by an antigen-detection test kit.

Influenza Virus Infection in Travelers to Tropical and Subtropical Countries

Background. Influenza outbreaks have been reported among travelers, but attack rates and incidence are unknown.

Temporal-Spatial Analysis of Severe Acute Respiratory Syndrome among Hospital Inpatients

Background. We report the temporal-spatial spread of severe acute respiratory syndrome (SARS) among inpatients in a hospital ward during a major nosocomial outbreak and discuss possible mechanisms for the outbreak.

Left Ventricular Assist Device—Related Infection: Treatment and Outcome

Background. Left ventricular assist device (LVAD) implantation has become an effective treatment option for patients with severe heart failure awaiting transplantation. Significant infection rates have been reported among LVAD recipients. However, few reports have focused specifically on device infection, its treatment, and the impact of LVAD-related infection on clinical outcome.

Changes in Renal Function Associated with Tenofovir Disoproxil Fumarate Treatment, Compared with Nucleoside Reverse-Transcriptase Inhibitor Treatment

In our large observational cohort, use of tenofovir disoproxil fumarate (n = 344) was associated with a greater decline in renal function than was use of alternative nucleoside analogues (n = 314). Other associations included a lower CD4 cell count, decreased renal function at baseline, and diabetes. The declines were modest and did not lead to greater rates of discontinuation of...

Use of Community-Based, Directly Observed Therapy for HIV Infection: Lessons Learned for Treatment of Hepatitis C Virus Infection

Directly observed therapy (DOT) is an effective approach for the treatment of tuberculosis among substance users. We have adapted this model to treat human immunodeficiency virus infection. Our experience suggests that community-based, modified DOT should be explored further as a means to treat infectious diseases and chronic medical illnesses for persons with drug dependence; it...