ABSTRACT Objectives: Helicobacter pylori, infection carryout a substantial role in the pathogenesis of gastric disorders. The pathogenic effect is shown to be associated with host bacterial interplay and Vac A and Cag A are recognized as imperative virulence determinants. A variety of carcinogenic pathways are triggered by H. pylori and CCL20 and β-actin are responsible for...
ABSTRACT Staphylococcus aureus is a Gram-positive bacterium found frequently on a person’s skin and sometimes in their upper respiratory tract. Although regarded primarily as a commensal of the human microbiota S. aureus shows the ability to become an opportunistic pathogen. Hence, it is a common cause of skin and lung infections and of food poisoning. S. aureus forms biofilms...
ABSTRACT We present a case of eruptive xanthoma in a man living with HIV after changing antiretroviral therapy. People living with HIV are at increased risk of dyslipidemia due to the infection itself and the use of antiretroviral medications. Prompt recognition of eruptive xanthomas may allow for timely diagnosis of metabolic disorders and dyslipidemia in patients being treated...
ABSTRACT Prevotella is a common gram-negative anaerobic rod that is frequently associated with female genitourinary tract infections, pelvic inflammatory disease, aspiration pneumonia, lung abscess and pleural empyema. Osteomyelitis in association with septic arthritis is rare with only a handful of cases reported worldwide. In this case study, we report a patient who presented...
ABSTRACT Schistosomiasis or Bilharziasis is a water-borne parasitic disease which affects different organs depending on species involved. Urinary schistosomiasis is diagnosed mainly by the presence of urinary complaints, urinary excretion of parasite eggs and their presence in bladder as seen on histopathology along with changes on cystoscopy. We present a case of an asymptomatic...
ABSTRACT Xanthogranulomatous pyelonephritis is an uncommon destructive process that is associated with urinary tract infection and/or obstruction. We present the case of a 63 year old female who had an unusual case of xanthogranulomatous pyelonephritis due to Streptococcus intermedius in the left kidney. CT scan revealed a chronic obstructive pyelonephritis with associated...
ABSTRACT Objectives: Objective: This study was designed to explore the role of different phenotypes of P. aeruginosa in the development, stability and persistence of biofilm. Methods: A total of seventeen (17) waterborne biofilm producing strains of P. aeruginosa were studied. These isolates were identified on the basis of typical phenotypic characters and the tube method was...
ABSTRACT Objectives: Fever of Unknown Origin (FUO) in children remains difficult to diagnose. This prospective, observational study aimed to determine the clinico-etiological profile and the role of clinical procedures in establishing the diagnosis. Methods: Children (between 1 month and 16 years) with prolonged fever meeting the criteria of FUO were included. A detailed medical...
ABSTRACT Objectives: Objective: The aim of this study is to describe the epidemiological surveillance of Carbapenem-Resistant Enterobacteriaceae (CRE) effected at the Neurological Hospital Carlo Besta, Milano, Italy. The primary causes in our division of multidrug-resistant (MDRs) infections in 2016 were K. pneumoniae and A. baumannii; the preventive actions have ensured the...
ABSTRACT Invasive fungal infections occur in 5-59% of solid organ transplant recipients. Among fungal infections, Cryptococcus remains a significant opportunistic infection in solid organ transplant recipients. The incidence of cryptococcal infection in solid organ recipients was about 2.8 per 100 transplant recipients. Mortality rates in organ transplant recipients with...
ABSTRACT Objectives: Candida species are endogenous fungus causing both mucosal and invasive infections. With the increasing rate of non-albicans Candida infections with varying susceptibilities, early and accurate species identification would help the clinician in befitting therapeutic management. So the interest in natural products secreted by a fungus Wickerhamomyces anomalus...
ABSTRACT Objectives: Sentinel studies have targeted prenatal women as they are largely descriptive of the reproductive bracket, and prevalence data may be extended to the general population. This study determined the seroprevalence of hepatitis C virus (HCV) infection among pregnant women attending antenatal clinic at the Cape Coast Metropolitan Hospital. Methods: Whole blood...
ABSTRACT Objective: Human Cytomegalovirus (CMV) is a member of the Herpesviridae family, with the ability to establish a long-lived latent infection. CMV infection causes problems in immunocompromised hosts undergoing organ and stem cell transplantation. The prevalence of CMV in adults varies in different geographic regions. The purpose of this study was to assess the prevalence...
ABSTRACT Objective: Street foods are well - known source for bacteriological contamination with pathogens, responsible for health hazards like food poisoning and diarrheal diseases. The present study was undertaken to analyze the bacteriological quality of ready - to - serve foods vended in the streets of Rajahmundry, Andhra Pradesh, India. Method: This cross-sectional study over...
ABSTRACT Objective: Urinary tract infection (UTIs) in child is serious public health problem especially in developing countries. This aimed at identifying factors associated with urinary tract infection and determining their diagnosis performances as well as resulting algorithms among Cameroonian under-five. Methods: A descriptive and analytical cross sectional study took place...
Alpha one anti-trypsin (A1AT) is a major serine protease inhibitor found circulating in human blood. A1AT related studies mainly focus on A1AT potential biomarker as well as therapeutic target in non-infectious diseases. Their findings indicate A1AT beneficial features may also be applied for monitoring and treating infectious disease. However, only a few studies have reviewed...
Nocardiosis is an opportunistic infection seen in people with impaired host defenses usually cell mediated immunity. It can involve a single organ or present as disseminated infection affecting multiple organ systems. We are reporting a case of 60 year old; an immunocompetent female presented with fever, cough, skin lesions and altered sensorium. Thorough systemic examination...
Objective: Municipal solid waste (MSW) landfills recently emerged as potential reservoirs of antibiotic resistance. However, little is known about the potentials of unsanitary landfill sites which are common in developing countries as reservoir of antibiotic resistance. In this study, we investigated the antibiotic resistance pattern and presence of selected resistance genes in...
Objective: There exist various diagnostic tests to detect visceral leishmaniasis, but the most efficient ones have not been demonstrated yet. Herein, we evaluated the accuracy of these diagnostic tests in Iran. Methodology: English and Persian database searching was done from 1993 to 2016. According to heterogeneity of the studies, estimations of the study were pooled by random...
Objective: Antibiotic resistance is a major public health issue globally fueled largely by its misuse. Controlling this problem would require an understanding of the levels of awareness of the population towards antibiotics. This study assessed the baseline information on the knowledge, attitude and practice towards antibiotics among university students in Ogun State Nigeria...
ABSTRACT Objective: Gastrointestinal (GI) panels have allowed for faster and accurate detection, treatment, and control of pathogens. Because of the large number of potential pathogens included in the panel the clinical significance and manifestations of some organisms, such as Enteroaggregative Escherichia coli (EAEC) and Enteropathogenic E. coli (EPEC), remains undetermined...
Alpha one anti-trypsin (A1AT) is a major serine protease inhibitor found circulating in human blood. A1AT related studies mainly focus on A1AT potential biomarker as well as therapeutic target in non-infectious diseases. Their findings indicate A1AT beneficial features may also be applied for monitoring and treating infectious disease. However, only a few studies have reviewed...
Nocardiosis is an opportunistic infection seen in people with impaired host defenses usually cell mediated immunity. It can involve a single organ or present as disseminated infection affecting multiple organ systems. We are reporting a case of 60 year old; an immunocompetent female presented with fever, cough, skin lesions and altered sensorium. Thorough systemic examination...
Objective: Municipal solid waste (MSW) landfills recently emerged as potential reservoirs of antibiotic resistance. However, little is known about the potentials of unsanitary landfill sites which are common in developing countries as reservoir of antibiotic resistance. In this study, we investigated the antibiotic resistance pattern and presence of selected resistance genes in...
Objective: There is an increasing incidence of Acinetobacter species causing serious hospital acquired infections such as blood stream infections (BSI), catheter associated urinary tract infections (CAUTI) and lower respiratory tract infections(LRTI) with high mortality rate of 30-75% in patients having long hospital stay especially in critical care units (CCUs). During the past...
