BioMedical Engineering OnLine

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List of Papers (Total 1,247)

Image-based quantitative analysis of tear film lipid layer thickness for meibomian gland evaluation

Dry eye syndrome is one of the most common ocular diseases, and meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye syndrome. When the tear film lipid layer becomes thin due to obstructive or hyposecretory meibomian gland dysfunction, the excessive evaporation of the aqueous layer can occur, and this causes evaporative dry eye syndrome. Thus, measuring the ...

Evaluation of normal swallowing functions by using dynamic high-density surface electromyography maps

Swallowing is a continuous process with substantive interdependencies among different muscles, and it plays a significant role in our daily life. The aim of this study was to propose a novel technique based on high-density surface electromyography (HD sEMG) for the evaluation of normal swallowing functions. A total of 96 electrodes were placed on the front neck to acquire ...

Image-based quantitative analysis of tear film lipid layer thickness for meibomian gland evaluation

Dry eye syndrome is one of the most common ocular diseases, and meibomian gland dysfunction (MGD) is the leading cause of evaporative dry eye syndrome. When the tear film lipid layer becomes thin due to obstructive or hyposecretory meibomian gland dysfunction, the excessive evaporation of the aqueous layer can occur, and this causes evaporative dry eye syndrome. Thus, measuring the ...

NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis

In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently ...

Prediction of high airway pressure using a non-linear autoregressive model of pulmonary mechanics

For mechanically ventilated patients with acute respiratory distress syndrome (ARDS), suboptimal PEEP levels can cause ventilator induced lung injury (VILI). In particular, high PEEP and high peak inspiratory pressures (PIP) can cause over distension of alveoli that is associated with VILI. However, PEEP must also be sufficient to maintain recruitment in ARDS lungs. A lung model ...

Automatic non-proliferative diabetic retinopathy screening system based on color fundus image

Non-proliferative diabetic retinopathy is the early stage of diabetic retinopathy. Automatic detection of non-proliferative diabetic retinopathy is significant for clinical diagnosis, early screening and course progression of patients. This paper introduces the design and implementation of an automatic system for screening non-proliferative diabetic retinopathy based on color ...

STAMPS: development and verification of swallowing kinematic analysis software

Swallowing impairment is a common complication in various geriatric and neurodegenerative diseases. Swallowing kinematic analysis is essential to quantitatively evaluate the swallowing motion of the oropharyngeal structures. This study aims to develop a novel swallowing kinematic analysis software, called spatio-temporal analyzer for motion and physiologic study (STAMPS), and ...

Solar UV exposure among outdoor workers in Denmark measured with personal UV-B dosimeters: technical and practical feasibility

Exposure to solar ultraviolet radiation is a well-known cause of skin cancer. This is problematic for outdoor workers. In Denmark alone, occupational skin cancer poses a significant health and safety risk for around 400,000 outdoor workers. Objective measures of solar ultraviolet radiation exposure are needed to help resolve this problem. This can be done using personal ultraviolet ...

Diabetic foot ulcer mobile detection system using smart phone thermal camera: a feasibility study

Nowadays, the whole world is being concerned with a major health problem, which is diabetes. A very common symptom of diabetes is the diabetic foot ulcer (DFU). The early detection of such foot complications can protect diabetic patients from any dangerous stages that develop later and may require foot amputation. This work aims at building a mobile thermal imaging system that can ...

Building a resistance to ignition testing device for sunglasses and analysing data: a continuing study for sunglasses standards

Sunglasses popularity skyrocketed since its advent. The ongoing trend led to the creation of standards to protect consumers from injuries and secondary hazards due to spectacles use. In Brazil, the corresponding standard is NBR ISO 12312-1:2015 and since there is no mandatory testing, evaluating sunglasses performance provides an insight into compliance with the standard. In a ...

Area asymmetry of heart rate variability signal

Heart rate fluctuates beat-by-beat asymmetrically which is known as heart rate asymmetry (HRA). It is challenging to assess HRA robustly based on short-term heartbeat interval series. An area index (AI) was developed that combines the distance and phase angle information of points in the Poincaré plot. To test its performance, the AI was used to classify subjects with: (i) ...

Parameters sensitivity assessment and heat source localization using infrared imaging techniques

At present, infrared (IR) imaging is used both as a non-invasive and a non-ionizing technology. Using an IR camera, it is possible to measure body surface temperature in order to detect tumors and malignant cells. Tumors have a high amount of vasculature and an enhanced metabolism rate, which may result in an increase in body surface temperature by several degrees above its normal ...

Implementation and validation of the extended Hill-type muscle model with robust routing capabilities in LS-DYNA for active human body models

In the state of the art finite element AHBMs for car crash analysis in the LS-DYNA software material named *MAT_MUSCLE (*MAT_156) is used for active muscles modeling. It has three elements in parallel configuration, which has several major drawbacks: restraint approximation of the physical reality, complicated parameterization and absence of the integrated activation dynamics. This ...

Evaluation of the effect of different sitting assistive devices in reclining wheelchair on interface pressure

Reclining wheelchair users often add one or more sitting assistive devices to their wheelchairs, but the effect of these additional sitting assistive devices on the risk of pressure ulcers has rarely been investigated. This study examined the four modes of reclining wheelchair without and with different sitting assistive devices, namely the back reclined mode, the lumbar support ...

Noise-assisted multivariate empirical mode decomposition for multichannel EMG signals

Ensemble Empirical Mode Decomposition (EEMD) has been popularised for single-channel Electromyography (EMG) signal processing as it can effectively extract the temporal information of the EMG time series. However, few papers examine the temporal and spatial characteristics across multiple muscle groups in relation to multichannel EMG signals. The experimental data was obtained from ...

Evaluation of cervical posture improvement of children with cerebral palsy after physical therapy based on head movements and serious games

This paper presents the preliminary results of a novel rehabilitation therapy for cervical and trunk control of children with cerebral palsy (CP) based on serious videogames and physical exercise. The therapy is based on the use of the ENLAZA Interface, a head mouse based on inertial technology that will be used to control a set of serious videogames with movements of the head. Ten ...

Identification of informative features for predicting proinflammatory potentials of engine exhausts

The immunotoxicity of engine exhausts is of high concern to human health due to the increasing prevalence of immune-related diseases. However, the evaluation of immunotoxicity of engine exhausts is currently based on expensive and time-consuming experiments. It is desirable to develop efficient methods for immunotoxicity assessment. To accelerate the development of safe alternative ...

Highly wearable cuff-less blood pressure and heart rate monitoring with single-arm electrocardiogram and photoplethysmogram signals

Background Long-term continuous systolic blood pressure (SBP) and heart rate (HR) monitors are of tremendous value to medical (cardiovascular, circulatory and cerebrovascular management), wellness (emotional and stress tracking) and fitness (performance monitoring) applications, but face several major impediments, such as poor wearability, lack of widely accepted robust SBP models ...

Tissue perfusion modelling in optical coherence tomography

Background Optical coherence tomography (OCT) is a well established imaging technique with different applications in preclinical research and clinical practice. The main potential for its application lies in the possibility of noninvasively performing “optical biopsy”. Nevertheless, functional OCT imaging is also developing, in which perfusion imaging is an important approach in ...

A 3D MRI denoising algorithm based on Bayesian theory

Background Within this manuscript a noise filtering technique for magnetic resonance image stack is presented. Magnetic resonance images are usually affected by artifacts and noise due to several reasons. Several denoising approaches have been proposed in literature, with different trade-off between computational complexity, regularization and noise reduction. Most of them is ...

ECG signal performance de-noising assessment based on threshold tuning of dual-tree wavelet transform

Background Since the electrocardiogram (ECG) signal has a low frequency and a weak amplitude, it is sensitive to miscellaneous mixed noises, which may reduce the diagnostic accuracy and hinder the physician’s correct decision on patients. Methods The dual tree wavelet transform (DT-WT) is one of the most recent enhanced versions of discrete wavelet transform. However, threshold ...

Fast time-varying linear filters for suppression of baseline drift in electrocardiographic signals

Background The paper presents a method of linear time-varying filtering, with extremely low computational costs, for the suppression of baseline drift in electrocardiographic (ECG) signals. An ECG signal is not periodic as the length of its heart cycles vary. In order to optimally suppress baseline drift by the use of a linear filter, we need a high-pass filter with time-varying ...