Journal of Nuclear Cardiology

http://link.springer.com/journal/12350

List of Papers (Total 807)

Calendar

Comparison of long-term mortality risk following normal exercise vs adenosine myocardial perfusion SPECT

Background A higher frequency of clinical events has been observed in patients undergoing pharmacological vs exercise myocardial perfusion single-photon emission computed tomography (SPECT). While this difference is attributed to greater age and co-morbidities, it is not known whether these tests also differ in prognostic ability among patients with similar clinical profiles...

Automatic and visual reproducibility of perfusion and function measures for myocardial perfusion SPECT

Background We define the repeatability coefficients (RC) of key quantitative and visual perfusion and function parameters that can be derived by the QGS/QPS automated software and by expert visual observer from gated myocardial perfusion SPECT (MPS) scans. Methods Standard QGS/QPS algorithms have been applied to derive quantitative perfusion and function parameters in 200 99mTc...

Early molecular imaging of interstitial changes in patients after myocardial infarction: Comparison with delayed contrast-enhanced magnetic resonance imaging

Introduction The clinical feasibility of noninvasive imaging of interstitial alterations after myocardial infarction (MI) was assessed using a technetium-99m-labeled RGD imaging peptide (RIP). In experimental studies, RIP has been shown to target integrins associated with collagen-producing myofibroblasts (MFB). Methods and Results Ten patients underwent myocardial perfusion...

Incremental prognostic value of left ventricular function analysis over non-invasive coronary angiography with multidetector computed tomography

Background The purpose of this study was to determine the prognostic value of computed tomography coronary angiography (CTA)-derived left ventricular (LV) function analysis and to assess its incremental prognostic value over the detection of significant stenosis using CTA. Methods In 728 patients (400 males, mean age 55 ± 12 years) with known or suspected CAD, the presence of...

Molecular imaging of inflammation and intraplaque vasa vasorum: A step forward to identification of vulnerable plaques?

Current developments in cardiovascular biology and imaging enable the noninvasive molecular evaluation of atherosclerotic vascular disease. Intraplaque neovascularization sprouting from the adventitial vasa vasorum has been identified as an independent predictor of intraplaque hemorrhage and plaque rupture. These intraplaque vasa vasorum result from angiogenesis, most likely...

Stress only myocardial perfusion imaging: Is it time for a change?

Stress single photon emission computed tomographic (SPECT) myocardial perfusion imaging has enjoyed great success over the past several decades as the modality of choice for accurately diagnosing and risk stratifying patients with suspected or known coronary artery disease. Same-day low-dose rest/high-dose stress imaging protocols have generally been widely adopted for this...

Phantom evaluation of a cardiac SPECT/VCT system that uses a common set of solid-state detectors for both emission and transmission scans

Background We developed a cardiac SPECT system (X-ACT) with low dose volume CT transmission-based attenuation correction (AC). Three solid-state detectors are configured to form a triple-head system for emission scans and reconfigured to form a 69-cm field-of-view detector arc for transmission scans. A near mono-energetic transmission line source is produced from the collimated...