International Urology and Nephrology

http://link.springer.com/journal/11255

List of Papers (Total 172)

Membranoproliferative glomerulonephritis and a rare bleeding disorder: factor X deficiency

Factor X (FX) deficiency is a rare hereditary coagulation disorder. This is the first case report on the association of FX deficiency and membranoproliferative glomerulonephritis (MPGN) type I. The patient, a 17-year-old male, presented with edema, hypertension, and microscopic hematuria, followed by a mild upper respiratory tract infection. Laboratory tests revealed: serum ...

Renal cell carcinoma of native kidney in Chinese renal transplant recipients: a report of 12 cases and a review of the literature

Objectives To present and discuss the epidemiological and clinical aspects, as well as therapeutic options and outcome of de novo renal cell carcinoma (RCC) of the native kidneys in a series of Chinese renal transplant recipients. Patients and Methods A retrospective, cohort study examining all renal transplant recipients with the diagnosis of RCC of native kidney followed up in ...

Effect of nutritional vitamin D preparations on parathyroid hormone in patients with chronic kidney disease

IntroductionVitamin D deficiency is common and may be a risk factor for nearly all major diseases, including cancer, infections, autoimmune and cardiovascular disease [1]. Vitamin D (VitD) stores decline with age, during winter, after menopause and in chronic kidney disease (CKD) [2]. VitD supplementation is advocated for the treatment of musculoskeletal disorders, for prevention ...

Influence of megestrol acetate on nutrition, inflammation and quality of life in dialysis patients

Aim Malnutrition is a common clinical problem in dialysis patients. The objective of this study was to evaluate the efficacy and safety of megestrol acetate in malnourished dialysis patients. Thirty-two hypoalbuminemic dialysis patients took 160 mg of megestrol acetate daily for up to 6 months. Methods We measured height, dry weight, BMI, modified Subjective Global Assessment (SGA) ...

Indinavir-induced nephrolithiasis three and one-half years after cessation of indinavir therapy

Nephrolithiasis is a known side effect of indinavir sulfate, a protease inhibitor used in the treatment of human immunodeficiency virus (HIV). The duration of its side effects, however, has not been well defined. We present a case where a patient presented with symptomatic indinavir-induced nephrolithiasis 3.5 years after discontinuing indinavir. We use this case to illustrate the ...

Update on potential medical treatments for encapsulating peritoneal sclerosis; human and experimental data

Encapsulating peritoneal sclerosis (EPS) is an infrequent but serious complication of peritoneal dialysis (PD). The pathogenesis is unknown but speculation is ongoing. The current management of EPS focuses on prevention and treatment of the inflammatory and fibrotic changes at the level of the peritoneal membrane with immunosuppressive and antifibrotic agents, respectively. This ...

New-onset diabetes after transplantation in tacrolimus-treated, living kidney transplantation: long-term impact and utility of the pre-transplant OGTT

Background To evaluate the role of the oral glucose tolerance test (OGTT) before transplantation and to examine the risk factors for new-onset diabetes after transplantation (NODAT) during long-term follow-up of renal transplant recipients receiving FK-based therapy. Methods The study evaluated 378 patients pre-transplantation using the OGTT and assigned them to one of three ...

Death with functioning kidney transplant: an obituarial analysis

Background Death with a functioning kidney graft (DWFG) is now a major cause of graft loss after renal transplantation, occurring in up to 40% of cases. Its occurrence provides insight into the medical care of subjects with a functioning kidney transplant. In this study, we used the time to DWFG as an endpoint, to test whether improved medical care has contributed to better kidney ...

Expression of P311, a transforming growth factor beta latency-associated protein-binding protein, in human kidneys with IgA nephropathy

Background In cultured NIH3T3 cells, P311 binds to the transforming growth factor-beta (TGF-β)-1 latency-associated protein (LAP) and induces the myofibroblast phenotype. In this study, we determined the levels of P311 and TGF-β1 proteins in tubulointerstitial tissue of patients with different severities of immunoglobulin-A nephropathy (IgAN), and analyzed the relationships between ...

Cardiovascular events in chronic dialysis patients: emphasizing the importance of vascular disease prevention

Cardiovascular disease is the leading cause of death in both chronic kidney disease and peritoneal dialysis/hemodialysis patients. Vascular disease prevention in these patients is therefore important to reduce the incidence of cardiovascular events and the high morbidity and mortality. This Editorial discusses the traditional, (1) smoking, (2) dyslipidemia, (3) body mass index, (4) ...

Hyperoxaluria after modern bariatric surgery: case series and literature review

Introduction Two recent studies have shown that modern bariatric surgery leads to significant hyperoxaluria and risk of nephrolithiasis. However, neither report evaluates the use or effects of stone risk modifying agents in these patients. We sought to determine the impact of medical management on stone risk profile in patients who have undergone Roux-en-y gastric bypass. Materials ...

Non-dipping phenomenon in patients with essential hypertension with renal cysts

Dear Editor,Afsar et al. [1] concluded that the presence of simple renal cysts is related to higher ambulatory blood pressure and with non-dipping phenomenon in patients with essential hypertension. Evidence has been shown about association of hypertension and simple renal cysts [2]. The actual and independent association of simple renal cysts and non-dipping phenomenon in ...

A new algorithm in patients with elevated and/or rising prostate-specific antigen level, minor lower urinary tract symptoms, and negative multisite prostate biopsies

Patients with elevated and/or rising prostate-specific antigen (PSA), minor lower urinary tract symptoms (LUTS), and no evidence for prostate cancer on (multiple) extended prostate biopsies are a regularly encountered problem in urological practice. Even now, patients are seen with no objective explanation of this persistent elevated and/or rising PSA. So far, many strategic ...