The Journal of Headache and Pain

http://link.springer.com/journal/10194

List of Papers (Total 1,879)

Anxiety and depression symptoms and migraine: a symptom-based approach research

Background Anxiety and mood disorders have been shown to be the most relevant psychiatric comorbidities associated with migraine, influencing its clinical course, treatment response, and clinical outcomes. Limited information is available on how specific anxiety and depression symptoms are related to migraine. Symptoms-based approach, a current trend in mental health research, may ...

Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia

Background Despite their huge epidemiological impact, primary headaches, trigeminal neuralgia and other chronic pain conditions still receive suboptimal medical approach, even in developed countries. The limited efficacy of current pain-killers and prophylactic treatments stands among the main reasons for this phenomenon. Botulinum neurotoxin (BoNT) represents a well-established ...

Disrupted functional connectivity of periaqueductal gray subregions in episodic migraine

Background The periaqueductal gray (PAG) dysfunction was recognized in migraine, and the altered dysfunction of PAG subregions were not totally detected up to now. The aim of this study is to investigate the altered functional connectivity of PAG subregions in EM patients. Methods The brain structural images and resting state functional MR imaging (rs-fMRI) data were obtained from ...

Association of excessive daytime sleepiness with migraine and headache frequency in the general population

Background Some previous studies have postulated an association between migraine and excessive daytime sleepiness (EDS). This study evaluated the association of EDS with migraine and headache frequency in a general population, after adjusting for potential confounding variables. Methods The study was a postal survey of a random age and gender-stratified sample of 40,000 persons ...