BMC Research Notes

http://link.springer.com/journal/13104

List of Papers (Total 5,662)

Collaborative modeling of an implementation strategy: a case study to integrate health promotion in primary and community care

Background Evidence-based interventions are more likely to be adopted if practitioners collaborate with researchers to develop an implementation strategy. This paper describes the steps to plan and execute a strategy, including the development of structure and supports needed for implementing proven health promotion interventions in primary and community care. Results Between 10 ...

Self-sampling for human papillomavirus testing among rural young women of KwaZulu-Natal, South Africa

Background Cervical cancer is a major problem in women and it is important to find a suitable and acceptable screening method, especially among young in low-resource areas for future human papillomavirus (HPV) vaccine follow-up investigations. The study sought to test the acceptability of self-sampling as well as the suitability of the specimen collecting devices. Methods ...

A pilot study to determine the effect of one physical therapy session on physical activity levels for individuals with chronic low back pain

Background A pilot study was conducted to quantify the effect size of changes in physical activity after of one session of physical therapy for individuals with chronic low back pain and to determine factors that predict daily sedentary activity time. Methods Fourteen subjects with at least 3 days of physical activity accelerometer data were analyzed before and after one session of ...

Selecting the right gate to identify relevant cells for your assay: a study of thioglycollate-elicited peritoneal exudate cells in mice

Objective In this study, we investigate the diversity and modulation of leukocyte populations represented in the gates defined by size and granularity at different time points of thioglycollate-induced peritonitis in mouse. Results The inflammatory cells were distributed into four regions (R1–R4) of a data plot graph defined by cell size and granularity. R1 and R2 contained ...

Structural and functional annotation of hypothetical proteins of human adenovirus: prioritizing the novel drug targets

Objective Human adenoviruses are small double stranded DNA viruses that provoke vast array of human diseases. Next generation sequencing techniques increase genomic data of HAdV rapidly, which increase their serotypes. The complete genome sequence of human adenovirus shows that it contains large amount of proteins with unknown cellular or biochemical function, known as hypothetical ...

Genetic investigation of XPA gene: high frequency of the c.682C>T mutation in Moroccan XP patients with moderate clinical profile

Objective Xeroderma pigmentosum (XP) is a genetically and clinically heterogeneous disease, associated with an inherited defect in one of eight different genes (XPA to XPG and XPV). In addition to the early onset of the skin manifestations, the XP group A is marked by the presence of a mild to severe neural disorders which appear tardily and worsens with age. In this study, 9 ...

A comparison of the effects of electronic reminders and group bonuses on the recording of diagnoses in primary care: a longitudinal follow-up study

Objective To improve the recording of diagnoses in visits to general practitioners, an observational retrospective study based on a before-after design was performed by installing an electronic reminder in the computerized patient chart system, reinforced in feedback delivered in superior-subordinate or development discussions with the general practitioners. The monthly rate of ...

Lipid-rafts remain stable even after ionizing radiation induced disintegration of β1 integrin containing focal adhesions

Objective Adhesion of cells to the extracellular matrix is facilitated by integrin receptors. We recently found that a nanoscale organization of plasma membrane located integrins containing the β1 subunit is responsible for an enhanced radio-resistance in 3D cultured cells over cells grown in 2D. While ionizing radiation is known to have broad effects on the lipid composition of ...

Validity and reliability of simple measurement device to assess the velocity of the barbell during squats

Objectives The velocity of a barbell can provide important insights on the performance of athletes during strength training. The aim of this work was to assess the validity and reliably of four simple measurement devices that were compared to 3D motion capture measurements during squatting. Nine participants were assessed when performing 2 × 5 traditional squats with a weight of ...

Selection of a suitable reference gene for quantitative gene expression in mouse lymph nodes after vaccination

Background The quantification of gene expression is an important tool in the evaluation of the immune response to vaccines. Reliable reference genes for gene expression studies in mouse draining lymph nodes after vaccination have not been reported. Results The utility of seven potential reference genes was investigated using commercially available Taq-man primer/probe mixes. ...

Molecular etiological profile of atypical bacterial pathogens, viruses and coinfections among infants and children with community acquired pneumonia admitted to a national hospital in Lima, Peru

Objective The main objective of this study was to detect the presence of 14 respiratory viruses and atypical bacteria (Mycoplasma pneumoniae, Chlamydia pneumoniae), via polymerase chain reaction in patients under 18 years old hospitalized due to community-acquired pneumonia (CAP) from Lima, Peru. Results Atypical pathogens were detected in 40% (58/146); viral etiologies in 36% ...

Junior Rounds: an educational initiative to improve role transitions for junior residents

Objective At our institution, Morning Report focuses mostly on diagnostic reasoning. This makes it a challenge for first-year residents to learn to manage common on-call emergencies, such as hyperkalemia. We sought to improve their preparedness for the transitions they would encounter: from medical student to physician at the beginning of the academic year, and from junior resident ...

Psychosocial effects of infertility among couples attending St. Michael’s Hospital, Jachie-Pramso in the Ashanti Region of Ghana

Objective Infertility is a life crisis with a wide range of socio-cultural, emotional, physical and financial problems. This study sought to determine the psychosocial effects of infertility among couples attending St. Michael’s hospital, Jachie-Pramso. A descriptive study design was adopted using a quantitative approach. A simple random technique was used to select 100 respondents ...

Short form version of the Quality of Trauma Care Patient-Reported Experience Measure (SF QTAC-PREM)

Objective To enable the valid and reliable measurement of patient experiences we previously published a multicenter multi-center validation of the Quality of Trauma Care Patient-Reported Experience Measure (QTAC-PREM). The purpose of this study was to derive a simplified, short form version of the QTAC-PREM to further enhance the feasibility of measuring patient experiences in ...

Unpublished systematic reviews and financial support: a meta-epidemiological study

Objective PROSPERO, an international prospective register of systematic reviews, was launched in February 2011 to reduce publication bias of systematic reviews (SRs). A questionnaire survey of SR researchers conducted in 2005 indicated the existence of unpublished SRs and the potential influence of lack of funding as a reason for non-publication. Here, we investigated the ...

Animations designed to raise patient awareness of prudent antibiotic use: patient recall of key messages and their immediate effect on patient attitude

Objectives This study aimed to determine if patients recalled key messages from antibiotic animations shown on digital displays in General Practice waiting rooms, and if watching them changed patients’ immediate intentions to consult their GP for upper respiratory tract infections, seek antibiotics and self-care. Results The pre intervention focus group found the animations ...

Joubert’s syndrome and related disorders and home-based peritoneal dialysis in East Africa: a case report

Background Joubert’s syndrome is a rare condition affecting an estimated 1:80,000–1:100,000 individuals. There is underdevelopment of the cerebellar vermis resulting in a characteristic molar tooth sign on cross sectional axial magnetic resonance imaging. It can occur in association with multi-organ involvement; in such cases it is classified as Joubert’s syndrome and related ...

Prognostic factors of nasopharyngeal carcinoma patients in a tertiary referral hospital: a retrospective cohort study

Background Nasopharyngeal carcinoma (NPC) exhibits a distinctive racial and geographic distribution. Many studies have reported varied significant prognostic factors affect the survival of NPC patients. Hence, this current study aimed to identify the prognostic factors of NPC patients registered in a tertiary referral hospital. Methods The records of one hundred and thirty-four NPC ...

Clinical interval and diagnostic characteristics in a cohort of bladder cancer patients in Spain: a multicenter observational study

Objective We performed a cohort study in seven hospitals in Spain to determine the clinical characteristics of incident patients with bladder cancer, the diagnostic process, and the conditions that might affect health care interval times. Results 314 patients with bladder cancer were included, 70.3 (Standard Deviation [SD] 11.2) years old and 85.0% male. Clinical stage was T1 in ...

Bacteriological study of calf colisepticemia in Alage Dairy Farm, Southern Ethiopia

Objective This study was designed to estimate the prevalence of E. coli which is the main cause of colisepticemia and the potential risk factors associated with the disease. A total of 74 calves less than 6 months age were selected for this study. For isolation and identification of E. coli, bacterial culture and biochemical tests were used. Result Out of 74 calves selected for ...

A systematic review and meta-analysis of psychological predictors of successful assisted reproductive technologies

Objectives The aim of this systematic review and meta-analysis was to perform an updated investigation of the effects of depression and anxiety on pregnancy outcomes following assisted reproductive technologies. A bibliographic search was performed using PubMed, PsycINFO, Embase, Science Direct databases. Data retrieved were analysed using a random effects model to estimate ...

Etiology of respiratory tract infections in the community and clinic in Ilorin, Nigeria

Objective Recognizing increasing interest in community disease surveillance globally, the goal of this study was to investigate whether respiratory viruses circulating in the community may be represented through clinical (hospital) surveillance in Nigeria. Results Children were selected via convenience sampling from communities and a tertiary care center (n = 91) during spring 2017 ...

Benefits of a mentoring support program for individuals with an eating disorder: a proof of concept pilot program

Objective The aim of this proof-of-concept pilot study was to assess the usefulness of a mentoring support program with a goal to improve hope for recovery in people with an eating disorder. Results Significant improvements (p ≤ 0.05) in hope for recovery were found for the mentees in the following domains: social relationships (p = 0.027), romantic relationships (p = 0.032), ...

Sexual health, risky sexual behavior and condom use among adolescents young adults and older adults in Chiang Mai, Thailand: findings from a population based survey

Background Sexual health is one of the key dimensions of health across all ages. Understanding risky sexual behaviors remains an important area of public health research. This study aimed to explore sexual health, risky sexual behaviors and factors associated with recent condom use as condom use is considered a main intervention proven to reduce negative health consequences of ...

Prevalence and intensity of Schistosoma mansoni infections among schoolchildren attending primary schools in an urban setting in Southwest, Ethiopia

Objective To determined both prevalence and intensity of Schistosoma mansoni infections among schoolchildren attending primary schools in Jimma town, an urban setting, Southwest, Ethiopia. Results The prevalence of S. mansoni infections was 8.4%. S. mansoni infections were found in all 17 schools, but the school prevalence ranged from 1.7 to 26.7%. This variation in prevalence ...