Canadian Journal of Gastroenterology and Hepatology

https://www.hindawi.com/journals/cjgh/

List of Papers (Total 128)

Giardiasis in Endoscopy Patients: A Comparison of Diagnostic Techniques

The results of a study comparing techniques for diagnosis of giardiasis during endoscopy are presented. Methods of diagnosis included examination of duodenal biopsy impression smears, culture of both biopsies and aspirates, and examination of preserved aspirate. Giardiasis was diagnosed in three of 80 patients; in each case the impression smear was positive. Cultures of duodenal...

Symptomatic Improvement of Gastroduodenal Crohn’s Disease with Omeprazole

Four patients with ileal Crohn’s disease presented with abdominal pain aggravated by food, a mean weight loss of 5.5 kg (range 4 to 7) and ulceration of the antrum and/or duodenum at gastroscnpy, without radiological features of mechanical obstruction . The endoscopic and histological appearance of the ulcers was consistent with Crohn's disease. Omeprazole 40 mg daily was...

The Social Toll of Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) – ulcerative colitis and Crohn’s disease – has become one the most important chronic digestive disorders found in the younger population. As a result of the nature of the illness, with remission and exacerbation of the inflammatory process, there has been increasing concern regarding the costs, both financial and social, of IBD. There have been...

Pain Management in Functional Gastrointestinal Disorders

Pain is a common feature in functional gastrointestinal disorders (FGID). An abnormally low visceral sensory threshold, as well as a number of central, spinal and peripheral pain-modulating abnormalities, have been proposed for this syndrome. Clinical aspects of pain associated with irritable esophagus, functional dyspepsia, biliary dysmotility, inflammatory bowel syndrome and...

Selecting Candidates for Liver Transplantation: A Medical Ethics Perspective on the Microallocation of a Scarce and Rationed Resource

Liver transplantation has evolved over the past 35 years from an experimental procedure with high perioperative mortality to an accepted form of treatment with an approximate 85% one-year and 80% three-year patient survival rate. Following the success and acceptance of transplantation in the treatment of end-stage liver disease, there has been a progressive increase in the number...

Meeting Review – Helicobacter pylori: Basic Mechanisms to Clinical Cure 2000

The meeting Helicobacter pylori: Basic Mechanisms to Clinical Cure 2000, held in Bermuda from March 26 to 29, 2000, gathered physicians and scientists from all corners of the world. State-of-the-art reviews and the most recent developments in the field were presented. This article summarizes the highlights of this meeting, including important scientific and clinical developments.

Nutrition of Liver Transplant Patients

Good cooperation between the hepatologist, surgeon and anesthesiologist is required to determine the appropriate perioperative nutritional management for the liver transplant patient. For preoperative risk stratification, nutritional assessment according to resting energy expenditure by indirect calorimetry, and body cell mass by bioelectrical impedence analysis, may be superior...

Solitary Rectal Ulcer Syndrome Presenting with Rectal Prolapse, Severe Mucorrhea and Eroded Polypoid Hyperplasia: Case Report and Review of the Literature

A case of solitary rectal ulcer syndrome in a 36-year-old woman presenting with severe, persistent mucorrhea and eroded polypoid hyperplasia as the predominant clinical features, who was ultimately noted to have symptoms of rectal prolapse, is presented. Endoscopically, she had multiple (50 to 60) small, whitish polypoid lesions in the rectum that were initially misinterpreted as...

Nonalcoholic Fatty Liver Disease in Patients Investigated for Elevated Liver Enzymes

Nonalcoholic fatty liver disease (NAFLD) is a common diagnosis among patients referred to gastroenterology and hepatology clinics for the evaluation of elevated liver enzymes. The diagnosis of NAFLD is supported by blood work to exclude other liver diseases, and by ultrasound evidence of fat in the liver in patients without a significant history of alcohol intake. The gold...

Helicobacter pylori and the Prevention of Gastric Cancer

BACKGROUND: Helicobacter pylori is an important cause of stomach cancer that infects a substantial proportion of the Canadian adult population. H pylori can be detected by noninvasive tests and effectively eradicated by medical treatment. Screening for and treatment of H pylori may represent a significant opportunity for preventive oncology.

Celiac and Perigastric Lymph Node Metastasis of Prostate Cancer Diagnosed with Endoscopic Ultrasound-Guided Fine-Needle Aspiration

Endoscopic ultrasound has been used to diagnose and stage gastrointestinal and nongastrointestinal tumours. To our knowledge, the present report describes the first case of celiac and perigastric lymph node metastasis of prostate cancer diagnosed with endoscopic ultrasound-guided fine-needle aspiration.

Evaluation and Management of Skeletal Health in Celiac Disease: Position Statement

OBJECTIVE: To review the evaluation and management of skeletal health in patients with celiac disease (CD), and to make recommendations on screening, diagnosis, treatment and follow-up of low bone mineral density (BMD) in CD patients.

Efficacy and Safety of Immunosuppressive Therapy for PBC–AIH Overlap Syndrome Accompanied by Decompensated Cirrhosis: A Real-World Study

Aim. To explore the efficacy and safety of immunosuppressive therapy for the treatment of primary biliary cirrhosis-autoimmune hepatitis (PBC-AIH) overlap syndrome accompanied by decompensated cirrhosis. Methods. A cohort study was performed to evaluate the usefulness of immunosuppressive therapy in this unique group. This cohort study was performed between October 2013 and June...

Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough

ACLF is a specific, but complex and multifactorial form of acute decompensation of cirrhosis and is characterized by an extraordinary dynamic natural course, rapidly evolving organ failure, and high short-term mortality. Dysbalanced immune function is central to its pathogenesis and outcome with an initial excessive systemic inflammatory response that drives organ failure and...

Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough

ACLF is a specific, but complex and multifactorial form of acute decompensation of cirrhosis and is characterized by an extraordinary dynamic natural course, rapidly evolving organ failure, and high short-term mortality. Dysbalanced immune function is central to its pathogenesis and outcome with an initial excessive systemic inflammatory response that drives organ failure and...

5-Aminosalicylic Acid Enemas in the Maintenance of Remission in Distal Ulcerative Colitis and Proctitis

A randomized clinical trial of the efficacy and safety of two different dosages of 5-aminosalicylic acid (5-ASA) enemas was carried out in 29 patients who had documented ulcerative colitis involving up to 50cm of distal colon. All patients were in remission or had minimal disease activity (Disease Activity Index [DAI] less than 4) at the time of study entry. The two patient...

Pyoderma Gangrenosum and Autoimmune Chronic Active Hepatitis in a 17-Year-Old Female

A 17-year-old girl presented with fever, icterus and painful small nodules on her face and a larger nodular lesion on the left shin. The patient had fatigue, intermittent jaundice and abdominal pain over the preceding three months. The nodular lesions ulcerated and had the typical clinical and histopathological appearance of pyoderma gangrenosum. Although there was no...

Healing of Benign Gastric and Prepyloric Ulcers: A Prospective, Endoscopy-Controlled, Randomized, Double-Blind, Canadian Multicentre Study of Omeprazole 20 and 40 mg Daily and Rantidine 150 mg Twice a Day

A double-blind, randomized study was conducted in 118 patients with benign gastric or prepyloric ulcers to compare the efficacy of omeprazole 20 or 40 mg daily with ranitidine 150 mg twice daily. The healing rates at four weeks were 67, 79 and 54% and at eight weeks increased to 90, 97 and 71 % for the omeprazole 20 and 40 mg groups and the ranitidine group, respectively (P< 0.03...

Hemochromatosis and Yersiniosis

Two patients with documented hemochromatosis and systemic infection with Yersinia enterocolitica are described. The first patient presented with Y enterocolitica septicemia and an infected hip prosthesis which led to the diagnosis of hemochromatosis. The second patient was previously treated for Y enterocolitica with antibiotics but did not recover fully until aggressive...