Canadian Journal of Gastroenterology and Hepatology

https://www.hindawi.com/journals/cjgh/

List of Papers (Total 880)

Thermal Methods for Therapy of Nonvariceal Bleeding

This presentation addresses the thermal methods for therapy of nonvariceal bleeding. The following subtopics will be considered: overview of thermal options, combination therapy, data, technique, conclusions regarding peptic ulcer therapy and unique situations.

Small Bowel Review: Part II

In the past year there have been many advances in the area of small bowel physiology and pathology. In preparation for this review, over 500 papers were assessed; some have been selected and reviewed, with a particular focus on presenting clinically useful information for the practising gastroenterologist.

Novel Diagnostic Tests to Detect Helicobacter pylori Infection: A Pediatric Perspective

Because of the widespread problem of Helicobacter pylori infections, there is an increased need for rapid, reliable and inexpensive diagnostic tests. Five recently developed tests that offer potential advantages because they are less invasive or permit easier acquisition of samples than available tests are assessed. The tests assessed are whole blood, saliva and urine assays that...

Survey of Access to GastroEnterology in Canada: The SAGE Wait Times Program

BACKGROUND: Assessment of current wait times for specialist health services in Canada is a key method that can assist government and health care providers to plan wisely for future health needs. These data are not readily available. A method to capture wait time data at the time of consultation or procedure has been developed, which should be applicable to other specialist groups...

Clinical Experience with 5-Aminosalicylate Preparations in Inflammatory Bowel Disease - A Review

The efficacy of 5-ASA tablets is around 65 co 70% in patients with active ulcerative colitis, whereas the efficacy of the rectal preparations approach 100% when the treatment is for active distal disease. When there is more extensive left sided colonic disease, the efficacy of 5-ASA rectal preparations is not as high, but it is still much improved over that seen with oral 5-ASA...

Hypothalamic Hypogonadism in Hemochromatosis: A Case Report

A 42-year-old man developed hypogonadotropic hypogonadism due to primary hemochromatosis. Endocrine evaluation indicated a hypothalamic defect in the control of gonadotropin secretion. Although cirrhosis was present on liver biopsy, ocher major features of the hemochromatosis syndrome were not manifest. Patients with hemochromacosis arc now being diagnosed at earlier stages of...

Adenocarcinoma of the Stomach in Celiac Disease

A case of adenocarcinoma of the gastric antrum in a woman with celiac disease of 21 years duration is presented. There was widespread intestinal metaplasia of the gastric antrum but the patient did not have typc A gastritis or dermatitis herpetiformis. Previous studies have shown that some patients with celiac disease have fundal gastritis but the natural history or premalignant...

Giardiasis in Endoscopy Patients: A Comparison of Diagnostic Techniques

The results of a study comparing techniques for diagnosis of giardiasis during endoscopy are presented. Methods of diagnosis included examination of duodenal biopsy impression smears, culture of both biopsies and aspirates, and examination of preserved aspirate. Giardiasis was diagnosed in three of 80 patients; in each case the impression smear was positive. Cultures of duodenal...

The Equivalence of Two Open Therapeutic Regimens of Cimetidine in the Treatment of Acute Duodenal Ulcer Disease: A Canadian Multicentre Trial

One hundred and four patients completed a multicentre study comparing the standard cimetidine regimen of 300 mg qid with cimetidine 600 mg bid in the treatment of acute duodenal ulcer. Both dosage regimens were effective in alleviating symptoms. At the two- and four-week assessments a significantly greater decrease in frequency, duration and severity of night time pain was...

Premalignant Lesions of the Colon

Cancer of the colon and rectum is the second most common cancer in men and women in North America. Early diagnosis results in detection of early stage tumours with a high probability of cure. Several studies document the efficacy of screening for the early detection of colorectal cancer; however, its incidence is so high chat screening the entire older adult population is not...

Esophageal Variceal Ligation

Endoscopic sclerotherapy is an effective method for treating and eradicating acutely bleeding varices in repeated sessions; however, it is not ideal because of numerous serious complications. Endoscopic variceal ligation, developed to circumvent some of the side effects of sclerotherapy, controls actively bleeding varices in about 90% of cases. Of 146 patients treated with...

Approach to Upper Gastrointestinal Bleeding - When to Treat?

Upper gastrointestinal bleeding from peptic ulcer is a life threatening emergency. Clinical risk factors for fatal outcome have been defined, and endoscopic predictors for rebleeding have been identified. Active ulcer bleeding at endoscopy carries an 80% chance of persistent or recurrent bleeding. A non bleeding visible vessel is associated with a 50% chance of rebleeding. These...

Liver Cirrhosis: A Seven Year Follow-Up

The status of 121 patients who were found to have liver cirrhosis on liver biopsy in 1981 was assessed seven years later. The etiology of the cirrhosis was alcoholic in 52%, cryptogenic in 29.8%, hepatitis B-related in 9.1% and miscellaneous in 9.1%. In 1981, jaundice was present in 55 patients (45.8%), ascites in 52 (43%), gastrointestinal bleeding in 25 (20.7%) and...

Duodenal Hematoma – A Case Report of Duodenal Atresia following Conservative Management of a Duodenal Hematoma

In children, duodenal hematomas following blunt abdominal trauma are routinely treated conservatively. A case of a two-and-a-half-year-old female in whom conservative management was unsuccessful is presented. At surgery she was found to have an atretic duodenum secondary to the duodenal hematoma. Although uncommon, fibrotic stenosis must be considered in a patient who fails to...

Defence Mechanisms during Intestinal Infection

This review examines and compares host defence mechanisms during intestinal infection with three types of organisms: a virus, a bacterium and a nematode parasite (ie, transmissible gastroenteritis virus [TGEV], Helicobacter jejuni and Trichinella spiralis). Diarrhea is commonly associated with all of these infections. It appears that T spiralis initiates the most elaborate...

Small Bowel Transplantation: Current Clinical Status

With recent refinements in immunosuppression techniques, the first successful reports of small bowel transplantation in humans have now been made, increasing interest in bowel transplantation among clinicians and patients alike. This article reviews recent developments in understanding of the functional capabilities and requirements for effective immune suppression in bowel...

Symptomatic Improvement of Gastroduodenal Crohn’s Disease with Omeprazole

Four patients with ileal Crohn’s disease presented with abdominal pain aggravated by food, a mean weight loss of 5.5 kg (range 4 to 7) and ulceration of the antrum and/or duodenum at gastroscnpy, without radiological features of mechanical obstruction . The endoscopic and histological appearance of the ulcers was consistent with Crohn's disease. Omeprazole 40 mg daily was...