European Radiology

https://link.springer.com/journal/330

List of Papers (Total 766)

Disk injury in patients with vertebral fractures—a prospective diagnostic accuracy study using dual-energy computed tomography

ObjectivesUsing magnetic resonance imaging (MRI) as the standard of reference, we aimed to evaluate the diagnostic accuracy of dual-energy computed tomography (DECT) in assessing disk injuries in patients aged more than 50 years with vertebral fractures.MethodsThis prospective study was approved by the local ethics committee (EA1/372/14), and all patients gave written informed...

Impact of guidelines for the management of minor head injury on the utilization and diagnostic yield of CT over two decades, using natural language processing in a large dataset

ObjectivesWe investigated the impact of clinical guidelines for the management of minor head injury on utilization and diagnostic yield of head CT over two decades.MethodsRetrospective before-after study using multiple electronic health record data sources. Natural language processing algorithms were developed to rapidly extract indication, Glasgow Coma Scale, and CT outcome from...

Citations in scientific articles: possibly biased reflections on the field of diagnostic imaging

This Editorial Comment refers to the article “Citation Bias in Imaging Research: Are studies with higher diagnostic accuracy estimates cited more often?” by Frank RA, Sharifabadi AD, Salameh JP et al, Eur Radiol. 2018 Nov 15.  https://doi.org/10.1007/s00330-018-5801-8 [1].

Multiparametric whole-body 3.0-T MRI in newly diagnosed intermediate- and high-risk prostate cancer: diagnostic accuracy and interobserver agreement for nodal and metastatic staging

ObjectivesTo determine the diagnostic accuracy and interobserver concordance of whole-body (WB)-MRI, vs. 99mTc bone scintigraphy (BS) and 18fluoro-ethyl-choline (18F-choline) PET/CT for the primary staging of intermediate/high-risk prostate cancer.MethodsAn institutional review board approved prospective cohort study carried out between July 2012 and November 2015, whereby 56 men...

Accuracy of automated patient positioning in CT using a 3D camera for body contour detection

ObjectiveTo assess the accuracy of a 3D camera for body contour detection and patient positioning in CT compared to routine manual positioning by radiographers.Methods and materialsFour hundred twenty-three patients that underwent CT of the head, thorax, and/or abdomen on a scanner with manual table height selection and 254 patients on a scanner with table height suggestion by a...

The value of post-mortem computed tomography of burned victims in a forensic setting

ObjectivesFire deaths are challenging fatalities for forensic pathologists, as the main question of whether death was due to the fire or not needs to be answered. In this retrospective study, we assessed whether post-mortem computed tomography (PMCT) has an added value prior to a forensic autopsy of burned victims.MethodsFrom 2008 to 2016, a PMCT was performed in 50 burned...

Microvascular characteristics of lower-grade diffuse gliomas: investigating vessel size imaging for differentiating grades and subtypes

ObjectivesVessel size imaging (VSI) could reveal average microvessel diameter. The aim was to investigate microvascular characteristics and the efficacy of VSI in lower-grade glioma (LGG) grading and subtype differentiation based on 2016 classification of central nervous system tumours.MethodsFifty-seven LGG (grade II/III, 36/21) patients who received VSI examination before...

Magnetic resonance enterography, small bowel ultrasound and colonoscopy to diagnose and stage Crohn’s disease: patient acceptability and perceived burden

ObjectivesTo compare patient acceptability and burden of magnetic resonance enterography (MRE) and ultrasound (US) to each other, and to other enteric investigations, particularly colonoscopy.Methods159 patients (mean age 38, 94 female) with newly diagnosed or relapsing Crohn’s disease, prospectively recruited to a multicentre diagnostic accuracy study comparing MRE and US...

Motion-corrected multiparametric renal arterial spin labelling at 3 T: reproducibility and effect of vasodilator challenge

ObjectivesWe investigated the feasibility and reproducibility of free-breathing motion-corrected multiple inversion time (multi-TI) pulsed renal arterial spin labelling (PASL), with general kinetic model parametric mapping, to simultaneously quantify renal perfusion (RBF), bolus arrival time (BAT) and tissue T1.MethodsIn a study approved by the Health Research Authority, 12...

Comparison between software volumetric breast density estimates in breast tomosynthesis and digital mammography images in a large public screening cohort

ObjectivesTo compare software estimates of volumetric breast density (VBD) based on breast tomosynthesis (BT) projections to those based on digital mammography (DM) images in a large screening cohort, the Malmö Breast Tomosynthesis Screening Trial (MBTST).MethodsDM and BT images of 9909 women (enrolled 2010–2015) were retrospectively analysed with prototype software to estimate...

Multidetector CT angiography of the Circle of Willis: association of its variants with carotid artery disease and brain ischemia

Purpose(1) to estimate the prevalence of Circle of Willis (CoW) variants in patients undergoing carotid endarterectomy, (2) to correlate these variants to controls and (3) cerebral ischemia depicted by computed tomography (CT).Materials and methodsAfter Institutional Review Board approval, data of 544 carotid endarterectomy patients (331 males, mean age 69±8 years) and 196...

Whole-body MRI for staging and interim response monitoring in paediatric and adolescent Hodgkin’s lymphoma: a comparison with multi-modality reference standard including 18F-FDG-PET-CT

ObjectivesTo prospectively investigate concordance between whole-body MRI (WB-MRI) and a composite reference standard for initial staging and interim response evaluation in paediatric and adolescent Hodgkin’s lymphoma.MethodsFifty patients (32 male, age range 6–19 years) underwent WB-MRI and standard investigations, including 18F-FDG-PET-CT at diagnosis and following 2–3...

Analysis of errors made on in utero MR studies of the foetal brain in the MERIDIAN study

ObjectivesIn utero magnetic resonance (iuMR) imaging to diagnose foetal brain abnormalities has been established and is supported by meta-analyses of retrospective and prospective studies. In this paper we describe and classify the iuMR errors made in the largest diagnostic accuracy study to date (MERIDIAN). We also correlate the error rates and types with the prior experience of...

Shear-wave elastography: a new potential method to diagnose ulnar neuropathy at the elbow

ObjectivesThe primary aim of this study was to verify if shear-wave elastography (SWE) can be used to diagnose ulnar neuropathy at the elbow (UNE). The secondary objective was to compare the cross-sectional areas (CSA) of the ulnar nerve in the cubital tunnel and to determine a cut-off value for this parameter accurately identifying persons with UNE.MethodsThe study included 34...

Task-based quantification of image quality using a model observer in abdominal CT: a multicentre study

ObjectiveWe investigated the variability in diagnostic information inherent in computed tomography (CT) images acquired at 68 different CT units, with the selected acquisition protocols aiming to answer the same clinical question.MethodsAn anthropomorphic abdominal phantom with two optional rings was scanned on 68 CT systems from 62 centres using the local clinical acquisition...

Comparing dual energy CT and subtraction CT on a phantom: which one provides the best contrast in iodine maps for sub-centimetre details?

ObjectivesTo compare contrast-to-noise ratios (CNRs) and iodine discrimination thresholds on iodine maps derived from dual energy CT (DECT) and subtraction CT (SCT).MethodsA contrast-detail phantom experiment was performed with 2 to 15 mm diameter tubes containing water or iodinated contrast concentrations ranging from 0.5 mg/mL to 20 mg/mL. DECT scans were acquired at 100 kVp...

Accuracy of semi-automated versus manual localisation of liver tumours in CT-guided ablation procedures

ObjectivesTo compare the accuracy of liver tumour localisation in intraprocedural computed tomography (CT) images of computer-based rigid registration or non-rigid registration versus mental registration performed by interventional radiologists.MethodsRetrospectively (2009-2017), 35 contrast-enhanced CT (CECT) images incorporating 56 tumours, acquired during CT-guided ablation...

Fast 3-T MR-guided transrectal prostate biopsy using an in-room tablet device for needle guide alignment: a feasibility study

ObjectivesTo assess the feasibility of adding a tablet device inside the scanner room to assist needle-guide alignment during magnetic resonance (MR)-guided transrectal prostate biopsy.MethodsTwenty patients with one cancer-suspicious region (CSR) with PI-RADS score ≥ 4 on diagnostic multiparametric MRI were prospectively enrolled. Two orthogonal scan planes of an MR fluoroscopy...

Post-hepatectomy liver failure after major hepatic surgery: not only size matters

ObjectivesTo compare the value of functional future liver remnant (functFLR) to established clinical and imaging variables in prediction of post-hepatectomy liver failure (PHLF) after major liver resection.MethodsThis retrospective, cross-sectional study included 62 patients, who underwent gadoxetic acid enhanced MRI and MDCT within 10 weeks prior to resection of ≥ 4 liver...

CT colonography: size reduction of submerged colorectal polyps due to electronic cleansing and CT-window settings

ObjectivesTo assess whether electronic cleansing (EC) of tagged residue and different computed tomography (CT) windows influence the size of colorectal polyps in CT colonography (CTC).MethodsA database of 894 colonoscopy-validated CTC datasets of a low-prevalence cohort was retrospectively reviewed to identify patients with polyps ≥6 mm that were entirely submerged in tagged...

Improved visualisation of early cerebral infarctions after endovascular stroke therapy using dual-energy computed tomography oedema maps

ObjectiveThe aim was to investigate whether dual-energy computed tomography (DECT) reconstructions optimised for oedema visualisation (oedema map; EM) facilitate an improved detection of early infarctions after endovascular stroke therapy (EST).MethodsForty-six patients (21 women; 25 men; mean age: 63 years; range 24–89 years) were included. The brain window (BW), virtual non...