OncoTargets and Therapy

https://www.dovepress.com/oncotargets-and-therapy-archive23

List of Papers (Total 1,924)

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro

Overexpression of lncRNA PTENP1 suppresses glioma cell proliferation and metastasis in vitro Su Hu,1,* Li Xu,1,2,* Lihua Li,1 Dongdong Luo,1 Hailin Zhao,1 Dan Li,1 Biao Peng1 1Department of Neurosurgery, The Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Guangzhou 510095, Guangdong, People’s Republic of China; 2Department of Neurosurgery, The Central...

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms

Coincident primary breast lymphoma and gastrointestinal stromal tumor: case series and molecular mechanisms Ethan B Ludmir,1,* Tyler Gutschenritter,1,* Chelsea C Pinnix,1 Jillian R Gunther,1 Loretta J Nastoupil,2 Joseph D Khoury,3 L Jeffrey Medeiros,3 Bouthaina S Dabaja,1 Sarah A Milgrom1 1Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center...

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1α

Prolyl hydroxylase domain 3 influences the radiotherapy efficacy of pancreatic cancer cells by targeting hypoxia-inducible factor-1alpha Li-rui Tang,1,* Jun-xin Wu,1,* Shao-li Cai,2 Yun-xia Huang,1 Xue-qing Zhang,1 Wan-kai Fu,1 Qing-yang Zhuang,1 Jin-luan Li1 1Department of Radiation Oncology, Fujian Medical University Cancer Hospital, Fujian Cancer Hospital, Fuzhou, China; 2Key...

Lipocalin 2: a potential therapeutic target for breast cancer metastasis

Lipocalin 2: a potential therapeutic target for breast cancer metastasis Chenxia Hu,1 Ke Yang,1 Mengjie Li,1 Weiping Huang,2 Fengxue Zhang,2 Hongqi Wang2 1School of Pharmaceutical Science, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China; 2The Research Center of Basic Integrative Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China...

MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells

MicroRNA-645 targets urokinase plasminogen activator and decreases the invasive growth of MDA-MB-231 triple-negative breast cancer cells Du Meng,1,* Ming Lei,2,* Yaxuan Han,3 Dongli Zhao,2 Xiaozhi Zhang,1 Yunyi Yang,1 Rui Liu1 1Department of Radio Oncology, The First Affiliated Hospital of Xi’an Jiaotong University School of Medicine, Xi’an 710061, Shaanxi Province, People’s...

The elevated glutaminolysis of bladder cancer and T cells in a simulated tumor microenvironment contributes to the up-regulation of PD-L1 expression by interferon-γ

The elevated glutaminolysis of bladder cancer and T cells in a simulated tumor microenvironment contributes to the up-regulation of PD-L1 expression by interferon-γ Liping Wang,1,* Xuecheng Yang,2,* Dan Li,1 Zhijuan Liang,1 Yuanbin Chen,1 Guofeng Ma,2 Yonghua Wang,2 Yongxin Li,3 Ye Liang,1 Haitao Niu1,2 1Key Laboratory, Department of Urology and Andrology, Affiliated Hospital of...

Clinical significance of serum total oxidant/antioxidant status in patients with operable and advanced gastric cancer

Clinical significance of serum total oxidant/antioxidant status in patients with operable and advanced gastric cancer Xue-Fang Du,1 Li-Li Zhang,1 De-Zhong Zhang,2 Lu Yang,1 Ying-Ying Fan,1 Shu-Ping Dong1 1Department of Gastroenterology, First Affiliated Hospital of Xin-Xiang Medical University, Henan, People’s Republic of China; 2Gastrointestinal Surgery, The First Affiliated...

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer

A correlation study of the expression of HA-CD44st and HER-2 in breast cancer Lu Ying Zhi,1,* Zhang Xu,2,* Li Ning,3 Li Jia Jin,1,4 Yan Hai Cui,1 Huang Guan Hong,1 Xin Jian Fang1 1Department of Medical Oncology, the Second People’s Hospital of Lianyungang (Lianyungang Hospital Affiliated to Bengbu Medical College), Lianyungang, Jiangsu 222000, People’s Republic of China...

Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo

Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo Yu Zhang,1,2,* Xiao Xi Zhang,3,* Rui Yan Yuan,1,4,* Tai Ren,1,4 Zi Yu Shao,1,4 Hong Fei Wang,1,4 Wei Long Cai,5 Li Tian Chen,1,4 Xu An Wang,4 Ping Wang2 1Shanghai Key Laboratory of Biliary Tract Disease Research, Xinhua Hospital...

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients

Overexpression of Romo1 is an unfavorable prognostic biomarker and a predictor of lymphatic metastasis in non-small cell lung cancer patients Hong Jun Kim,1 Min Jee Jo,2 Bo Ram Kim,2 Jung Lim Kim,2 Yoon A Jeong,2 Yoo Jin Na,2 Seong Hye Park,2 Suk-young Lee,1 Dae-Hee Lee,1,2 Baek-hui Kim,3 Young Do Yoo,4 Sang Cheul Oh1,2 1Division of Oncology and Hematology, Department of Internal...

Comparable efficacy and less toxicity of pegylated liposomal doxorubicin versus epirubicin for neoadjuvant chemotherapy of breast cancer: a case-control study

Comparable efficacy and less toxicity of pegylated liposomal doxorubicin versus epirubicin for neoadjuvant chemotherapy of breast cancer: a case-control study Minjun Dong,1 Liang Luo,2 Xiaogang Ying,3 Xianqiu Lu,3 Jianguo Shen,1 Zhinong Jiang,4 Linbo Wang1 1Department of Surgical Oncology, 2Department of Gastroenterology, Sir Run Run Shaw Hospital, 3Zhejiang University School of...

Matrix metalloproteinase-7 may serve as a novel biomarker for cervical cancer

Matrix metalloproteinase-7 may serve as a novel biomarker for cervical cancer Linyan Zhu,* Xiaojiao Zheng,* Yongming Du, Yan Xing, Kejun Xu, Lining Cui Department of Obstetrics and Gynaecology, Ningbo First Hospital, Ningbo, Zhejiang, People’s Republic of China *These authors contributed equally to this work Background: The biological and clinical significance of matrix...

CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway

CEP55 promotes the proliferation, migration and invasion of esophageal squamous cell carcinoma via the PI3K/Akt pathway Yang Jia, Zhaohua Xiao, Xin Gongsun, Zhongwei Xin, Bin Shang, Gang Chen, Zhou Wang, Wenpeng Jiang Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China Background: Centrosomal protein 55 (CEP55) is an...

Progress in the treatment of solid tumors with apatinib: a systematic review

Progress in the treatment of solid tumors with apatinib: a systematic review Deze Zhao, Helei Hou, Xiaochun Zhang Department of Medical Oncology, The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266003, China Abstract: With the investigation of molecular targets, many agents, such as trastuzumab and ramucirumab, have attained a positive outcome in...

Efficacy and safety assessment of apatinib in patients with advanced gastric cancer: a meta-analysis

Efficacy and safety assessment of apatinib in patients with advanced gastric cancer: a meta-analysis Jianxin Chen,1 Junhui Wang2 1Department of Medical Oncology, Quzhou People’s Hospital, Quzhou, 324000, Zhejiang, People’s Republic of China; 2Department of Radiation Oncology, Quzhou People’s Hospital, Quzhou, 324000, Zhejiang, People’s Republic of China Aim: This meta-analysis...

Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis

Prognostic and clinicopathological significance of Beclin-1 in non-small-cell lung cancer: a meta-analysis Tianliang Zheng,1,* Deping Li,2,* Zhanfeng He,1 Shuaibing Feng,1 Song Zhao1 1Department of Thoracic Surgery, The First Affiliated Hospital of Zhengzhou University, 2Department of Pain Management, Zhengzhou Hospital of Traditional Chinese Medicine, Zhengzhou, China *These...

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3β/β-catenin signaling pathway

DcR3 induces proliferation, migration, invasion, and EMT in gastric cancer cells via the PI3K/AKT/GSK-3beta/beta-catenin signaling pathway Hua Ge, Chaojie Liang, Zhixia Li, Dali An, Shulin Ren, Chaosen Yue, Jixiang Wu Department of General Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China Background: Decoy receptor 3 (DcR3) has been reported to be...

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells

SIK1-LNC represses the proliferative, migrative, and invasive abilities of lung cancer cells Liu Yang,1,* Nianlin Xie,2,* Jingyu Huang,3,* Hu Huang,4,* Shaogan Xu,5 Zhigang Wang,4 Jun Cai6 1Department of Cancer Biotherapy Center, Hubei Cancer Hospital, Wuhan 430079, Hubei, People’s Republic of China; 2Department of Thoracic Surgery, Tangdu Hospital, The Fourth Military Medical...

Identification of potential core genes in triple negative breast cancer using bioinformatics analysis

Identification of potential core genes in triple negative breast cancer using bioinformatics analysis Man-Xiu Li, Li-Ting Jin, Tie-Jun Wang, Yao-Jun Feng, Cui-Ping Pan, Dei-Mian Zhao, Jun Shao Department of Breast Cancer, Hubei Cancer Hospital, Wuhan, People’s Republic of China Background: Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor clinical...

Pleiotropic functions of miR107 in cancer networks

Pleiotropic functions of miR107 in cancer networks Zhiying Luo,1,2 Yi Zheng,3 Wei Zhang1,2 1Department of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, Hunan, China; 2Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Central South University, Changsha, Hunan, China; 3Department of Pharmacy, Hunan Province Maternal and...

TERT copy gain predicts the outcome of high-dose interferon α-2b therapy in acral melanoma

TERT copy gain predicts the outcome of high-dose interferon alpha-2b therapy in acral melanoma Sifan Yu,* Tianxiao Xu,* Jie Dai, Meng Ma, Huan Tang, Zhihong Chi, Lu Si, Chuanliang Cui, Xinan Sheng, Yan Kong, Jun Guo Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Renal Cancer and Melanoma, Peking University Cancer...

Long-term progression-free survival of third-line apatinib in lung squamous cell carcinoma

Long-term progression-free survival of third-line apatinib in lung squamous cell carcinoma Xiaofen Li,1,2,* Xia Li,3,* Xuefeng Fang,1 Ying Yuan1 1Department of Medical Oncology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; 2Department of Abdominal Oncology, West China Hospital, Sichuan University, Chengdu, Sichuan, China...

New PDL1 inhibitors for non-small cell lung cancer: focus on pembrolizumab

New PDL1 inhibitors for non-small cell lung cancer: focus on pembrolizumab Olivier Bylicki,1 Nicolas Paleiron,2 Gaëlle Rousseau-Bussac,3 Christos Chouaïd3 1Pneumology Department, Hôpital d’Instruction des Armées Percy, Paris, 2Respiratory Department, Hôpital d’Instruction des Armées Saint-Anne, Toulon, 3Pneumology Department, CHI Créteil, Paris, France Abstract: The advent of...

MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9)

MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9) Ruibao Liu, Fang Wang, Yanchun Guo, Jianmei Yang, Shaoping Chen, Xin Gao, Xunguo Wang Department of Oncology, Dongying People’s Hospital, Dongying, Shandong 257091, People’s Republic of China Purpose: We aimed to investigate the roles of microRNA-425 (miR-425...

MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42

MicroRNA-384 inhibits proliferation migration and invasion of glioma by targeting at CDC42 Gengshi Gu,1,* Li Wang,1,* Junchen Zhang,1 Hao Wang,2 Tan Tan,1 Guangning Zhang1 1Department of Neurosurgery, Affiliated Hospital of Jining Medical University, Jining, Shandong 272000, People’s Republic of China; 2Department of Clinical Laboratory, Chinese People’s Liberation Army General...