Pakistan Journal of Neurological Sciences (PJNS)

http://ecommons.aku.edu/pjns/

List of Papers (Total 218)

Eight – and - half syndrome: a rare neuro-ophthalmic syndrome “Possible Nine Syndrome”

“Eight-and-half” syndrome is “one-and-a-half” syndrome characterized by conjugated horizontal gaze palsy and internuclearopthalmoplegia plus ipsilateral fascicular seventh nerve palsy. We report a case of 50 year old woman who presented with right eight and half syndrome together with contralateral hemiparesis and hemihypesthesia. Non contrast CT scan brain showed...

Under recognized entity: chronic inflammatory demyelinating polyneuropathy with lupus

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired, autoimmune peripheral neuropathy. It has an insidious disease progression resulting in a debilitating illness. It is a well known neurological disorder. The causative factors are elucidating and it is generally considered idiopathic. However, its’ associations with various systemic disorders is well...

Marburg variant of multiple sclerosis; a diagnostic and therapeutic challenge

Marburg variant of multiple sclerosis (MS) is a highly aggressive, fulminant demyelinating disease with very high morbidity and mortality. Early diagnosis and aggressive management is vital to limit severe disability and improve the outcome. We present a case of 35 years old male who presented with rapidly progressive demyelinating illness, leading to bed bound status over the...

Encephalopathy with behavioral and psychiatric features–firstantibody proven case of Anti-NMDA receptor encephalitis from Pakistan

Background: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is associated with psychiatric symptoms, memory disturbances, seizures, dyskinesia, and catatonia along with other constellation of symptoms. It is more common in females and usually associated with underlying ovarian teratoma. Treatment involves immunosuppression. This is the first antibody proven case from...

Stress induced hyperglycemia in stroke patients

Background: Stroke is the third most common cause of death in developed countries and second most common cause of death worldwide. High proportion of patients may develop hyperglycemia after an acute stress such as stroke or myocardial infarction even in the absence of preexisting diagnosis of diabetes mellitus. Prolonged stress hyperglycemia in ischemic stroke increases the risk...

Relationship between fear, fall & balance in cummunity dwelling older adults

Background: In older population the risk of fall is always at high risk and there are many contributing factor which increase the prevalence of fall. The impaired balance leads to limited daily activities and confidence level. Purpose of the study: The main purpose of this study was to determine the relationship between fall, fear and balance in older population. Method...

Hyperhomocysteinemia - An unidentified risk factor for stroke in our population

Introduction: Various studies show that moderate elevation of plasma homocysteine level has been associated with increased risk for cardiovascular and cerebrovascular disease. Objective: To observe the frequency of increased homocysteine level in ischemic stroke patients; and its association with other risk factors. Methodology: Observational pilot study was conducted on a sample...

Stroke rehabilitation in pakistan: what we know and what we need to do?

Stroke is one of the leading causes of adult neurological disability all around the globe. There have been some remarkable improvements in the acute management of stroke. These include the use of thrombolysis, development of radiological investigations including computerized tomographic scan and magnetic resonance imaging and establishment of acute stroke units. There have been...

Cost-effective practice of neurology: an idea whose time has come

Pakistanis spent $ 7.2 billion on healthcare in 2013 (3.1% of our Gross Domestic Product), representing a per capita expenditure of $ 39.4. The government contribution to this was no more than 31.4% ($ 12.4 per capita). The public allocations to health thus represent a paltry 4.7% of total government expenditure and are just shy of 1% of our GDP.