Aging Clinical and Experimental Research

http://link.springer.com/journal/40520

List of Papers (Total 71)

Frailty syndrome and rehospitalizations in elderly heart failure patients

Background Heart failure (HF) patients with frailty syndrome (FS) are at higher risk of falling, decreased mobility, ability to perform the basic activities of daily living, frequent hospitalizations, and death. Aims The purpose of this study was to evaluate the correlations between FS and hospital readmissions, and to assess which factors are associated with rehospitalizations. ...

How clinical practitioners assess frailty in their daily practice: an international survey

Introduction Various operational definitions have been proposed to assess the frailty condition among older individuals. Our objective was to assess how practitioners measure the geriatric syndrome of frailty in their daily routine. Methods An online survey was sent to national geriatric societies affiliated to the European Union Geriatric Medicine Society (EUGMS) and to members of ...

Impact of tooth loss on walking speed decline over time in older adults: a population-based cohort study

Background Tooth loss has been linked to poor health such as chronic diseases and mobility limitations. Prospective evidence on the association between tooth loss and walking speed decline is however lacking. Aims To examine the impact of tooth loss on walking speed over time and explore whether inflammation may account for this association. Methods This study included 2695 persons ...

Do we need orthogeriatrics in Poland? Changes in the age structure and location of hip fractures

Background Patients with hip fractures present a great challenge for surgeons due to multimorbidity, polypharmacy as well as difficulty in communicating. These could be attributed to a recent trend in the aging patient population (80 years and older) as compared to the past. The aim of this study is to analyze age structure and location in male and female patients’ population with ...

Thigh muscle and subcutaneous tissue thickness measured using ultrasound imaging in older females living in extended care: a preliminary study

Background Thigh tissue thickness has not been examined in older females living in extended care in UK as an indicator of musculoskeletal health. This study examined the feasibility of using ultrasound imaging to measure the thickness of superficial (fat) and deep layers (muscle) of the thigh in older females living in extended care. Methods In ten older females in extended care ...

Self-perceived care needs in older adults with joint pain and comorbidity

Background The aim of this study was to explore self-perceived care needs and determinants of identified needs in older adults with joint pain and comorbidity. Methods This is a cross-sectional study using baseline data from a cohort study of older adults in the Netherlands (≥65 years) with joint pain and comorbidity (n = 407). We used the Camberwell Assessment of Need for the ...

Hematological parameters and all-cause mortality: a prospective study of older people

Background The effect of low and high concentration of some hematological parameters in the blood can have a negative impact on health. Aim Therefore, we investigated the associations between hematological parameters and all-cause mortality among older people living in Poland. Methods The study was carried out among 75–80-year-old participants (n = 403) from Warsaw and Olsztyn ...

The 13-year observation of hip fracture in Poland—worrying trend and prognosis for the future

Introduction Hip fractures are often considered to be one of the most common osteoporotic fractures. In our previous study, we noted the increasing trend in the total number of hip fractures as well as crude and standardized rates, for both women and men. This observation enabled us to delve deeper into the study of osteoporotic fractures. Methods Hospital records between 1.01.2002 ...

Ginkgo biloba special extract LI 1370 improves dual-task walking in patients with MCI: a randomised, double-blind, placebo-controlled exploratory study

Background In patients with mild cognitive impairment (MCI), gait instability, particularly in dual-task situations, has been associated with impaired executive function and an increased fall risk. Ginkgo biloba extract (GBE) could be an effective mean to improve gait stability. Aims This study investigated the effect of GBE on spatio-temporal gait parameters of MCI patients while ...

Possibilities of ICT-supported services in the clinical management of older adults

Services making use of information and communication technology (ICT) are of potential interest to face the challenges of our aging society. Aim of this article is to describe the possible field of application for ICT-supported services in the management of older adults, in particular those with functional impairment. The current status of ICT-supported services is described and ...

Objective measurement of gait parameters in healthy and cognitively impaired elderly using the dual-task paradigm

Objectives The present study explores the differences in gait parameters in elderly subjects with or without cognitive impairment measured by means of ambulatory actigraphy while performing a single and a dual task. Methods Sixty-nine participants of which 23 individuals were diagnosed with Alzheimer’s disease (AD), 24 individuals with mild cognitive impairment (MCI), and 22 ...

Development and validation of a frailty index in the Longitudinal Aging Study Amsterdam

Background Frailty is a state of increased vulnerability to adverse outcomes. The frailty index (FI), defined by the deficit accumulation approach, is a sensitive instrument to measure levels of frailty, and therefore important for longitudinal studies of aging. Aims To develop an FI in the Longitudinal Aging Study Amsterdam (LASA), and to examine the predictive validity of this FI ...

Pancreatic stump closure after pancreatoduodenectomy in elderly patients: a retrospective clinical study

Background Pancreatic fistula (PF) after pancreatoduodenectomy (PD) represents the major source of morbidity. Derivative procedures are preferred by pancreatic surgeons, but the optimal management of remnant pancreatic stump remains controversial. Aims The purpose of this retrospective study is to evaluate the efficacy and safety of pancreatic stump closure in selected elderly ...

Second-generation drug-eluting stents in the elderly patients with acute coronary syndrome: the in-hospital and 12-month follow-up of the all-comer registry

Background Katowice–Zabrze registry provides data that can be used to evaluate clinical outcomes of percutaneous coronary interventions in elderly patients (≥70 y/o) treated with either first- (DES-I) or second-generation (DES-II) drug-eluting stents (DES). Methods The registry consisted of data from 1916 patients treated with coronary interventions using either DES-I or DES-II ...

Association between GDF-15 levels and changes in vascular and physical function in older patients with hypertension

Background Growth differentiation factor-15 (GDF-15) may be a biomarker of disease, protective response and/or prognosis, in older people with hypertension. Aims To correlate baseline GDF-15 levels with physical and vascular health data in this population. Methods Baseline blood samples were analysed using a GDF-15 ELISA assay kit. Correlations with baseline and 12-month outcome ...

Memory strategy use in older adults with subjective memory complaints

Background Subjective memory complaints (SMC) are common among older adults, but it is unclear to what extent adults with SMC spontaneously use memory strategies to compensate for their memory problems. As SMC may be a risk factor for memory decline later, it is important to extend our knowledge about spontaneous compensatory mechanisms in older adults with SMC. Method ...