Forensic Science, Medicine, and Pathology

http://link.springer.com/journal/12024

List of Papers (Total 130)

The radiodensity of cerebrospinal fluid and vitreous humor as indicator of the time since death

Purpose After death, a series of changes occur naturally in the human body in a fairly regular pattern. These postmortem changes are detectable on postmortem CT scans (PMCT) and may be useful in estimating the postmortem interval (PMI). The purpose of our study is to correlate the PMCT radiodensities of the cerebrospinal fluid (CSF) and vitreous humor (VH) to the PMI. Methods...

Hyoid bone fusion and bone density across the lifespan: prediction of age and sex

The hyoid bone supports the important functions of swallowing and speech. At birth, the hyoid bone consists of a central body and pairs of right and left lesser and greater cornua. Fusion of the greater cornua with the body normally occurs in adulthood, but may not occur at all in some individuals. The aim of this study was to quantify hyoid bone fusion across the lifespan, as...

Identifying cases of heroin toxicity where 6-acetylmorphine (6-AM) is not detected by toxicological analyses

Purpose Heroin has a half-life of 2–6 min and is metabolized too quickly to be detected in autopsy samples. The presence of 6-acetylmophine (6-AM) in urine, blood, or other samples is convincing evidence of heroin use by a decedent, but 6-AM itself has a half-life of 6–25 min before it is hydrolyzed to morphine, so 6-AM may not be present in sufficient concentration to detect in...

Classification of forensically-relevant larvae according to instar in a closely related species of carrion beetles (Coleoptera: Silphidae: Silphinae)

Carrion beetle larvae of Necrodes littoralis (Linnaeus, 1758), Oiceoptoma thoracicum (Linnaeus, 1758), Thanatophilus sinuatus (Fabricius, 1775), and Thanatophilus rugosus (Linnaeus, 1758) (Silphidae: Silphinae) were studied to test the concept that a classifier of the subfamily level may be successfully used to classify larvae according to instar. Classifiers were created and...

Validation of temperature methods for the estimation of pre-appearance interval in carrion insects

The pre-appearance interval (PAI) is an interval preceding appearance of an insect taxon on a cadaver. It decreases with an increase in temperature in several forensically-relevant insects. Therefore, forensic entomologists developed temperature methods for the estimation of PAI. In the current study these methods were tested in the case of adult and larval Necrodes littoralis...

Sudden unexpected death in early childhood: general observations in a series of 151 cases

Purpose The purpose of this study was to determine the major subcategories and clinicopathologic features of sudden unexpected death in young children in a large retrospective cohort, and to confirm the association of sudden unexplained death in children (abbreviated by us for unexplained deaths as SUDC) with hippocampal pathology and/or febrile seizures. Methods We undertook...

Subdural hematomas: glutaric aciduria type 1 or abusive head trauma? A systematic review

Purpose Glutaric aciduria type 1 (GA1) is a rare metabolic disorder of glutaryl-CoA-dehydrogenase enzyme deficiency. Children with GA1 are reported to be predisposed to subdural hematoma (SDH) development due to stretching of cortical veins secondary to cerebral atrophy and expansion of CSF spaces. Therefore, GA1 testing is part of the routine work-up in abusive head trauma (AHT...

Assigning cause for sudden unexpected infant death

We have reached a conundrum in assigning cause of death for sudden unexpected infant deaths. We summarize the discordant perspectives and approaches and how they have occurred, and recommend a pathway toward improved consistency. This lack of consistency affects pediatricians and other health care professionals, scientific investigators, medical examiners and coroners, law...