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Prevalence of HIV-associated malignancies among PLWHAs accessing HIV services in Abia State, Nigeria
Infectious
Agents and Cancer
Prevalence of HIV-associated malignancies among PLWHAs accessing HIV services in Abia State, Nigeria
Charles Adisa 1
Onyeonoro Ugochukwu 1
Aniele Agu 1
Ndukauba Eleweke 1
Chisara Umezurike Onwuchekwa 0
From
th International Conference on Malignancies in AIDS
Other Acquired Immunodeficiencies (ICMAOI) Bethesda
USA.
April
0 Nigerian Christian Hospital , Nlagu , Nigeria
1 Surgery Department, Abia State University , Aba , Nigeria
365.9+299.8 for females and 285+262.9 for males. 33.8% and 48.1% of the females and males, respectively, were eligible for ART based on CD4 cell count of 200 cells/ mm3. The mean CD4 cell count at presentation for males eligible for ART was 78.1 64.5 cells/mm3 compared with 91.760.5 cells/mm3 for females. No case of malignancy has been reported among those reviewed so far.
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Background
Malignancies are features of late HIV presentation. In
Nigeria the eligibility criteria for enrollment into ART
programme is CD4 cell count 200 cells/mm3 or stage of IV
of HIV/AIDS. Studies linking HIV/AIDS databases to
cancer registries have shown a decrease in AIDS-related
malignancies and an increase in nonAIDS-defining
malignancies. However, in Nigeria, pattern and prevalence
of malignancies among PLHWAs are understudied. The
objective of this study was to determine the pattern and
prevalence of HIV-associated malignancies among
PLWHAs in Abia State, Nigeria.
Methodology
This was a retrospective review of records of PLWHAs
assessing care in 3 selected ART centers in the State. The
3 centers which comprised 2 tertiary, and a secondary,
health care facilities were purposely selected because they
accounted for about 70% of the total client load of
PLWHAs in the State. All records of patients who have
accessed care in the facilities since 2007, when ART
programme commenced in the State, were reviewed. Relevant
data such as sex, age, CD4 cell count at first visit, clinical
stage of HIV disease, year of enrollment, presence of OIs,
and presence of malignancies were collected. Data
collected were analyzed using SPSS version 15.
Results
Of the 896 patients record so far reviewed, 68% were
females and 32% males. Mean age was 32.59.6 years for
females and 44.911.7 years for males. 80% of them had
their CD4 cell count at first visit recorded in their
treatment card. The mean CD4 cell counts at presentation were
Conclusion
Although with CD4 cell count of <500 cell/mm3 one
would have expected increasing prevalence of
malignancies among the patients, none was so far reported. This
is probably because the ART card/proforma used in
capturing the data from enrolled patients has no
provision to capture malignancies or HIV care providers and
lacks resources required for diagnosis of cancers. There
is therefore a need for health care providers to be
properly trained to detect malignancies in PLWHA and also
increase their indices of suspicion.
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