Comparison of strain imaging techniques in CRT candidates: CMR tagging, CMR feature tracking and speckle tracking echocardiography
Comparison of strain imaging techniques in CRT candidates: CMR tagging, CMR feature tracking and speckle tracking echocardiography
Wouter M. van Everdingen 0 1 2 3 4 5 6 7
Alwin Zweerink 0 1 2 3 4 5 6 7
Robin Nijveldt 0 1 2 3 4 5 6 7
Odette A. E. Salden 0 1 2 3 4 5 6 7
Mathias Meine 0 1 2 3 4 5 6 7
Alexander H. Maass 0 1 2 3 4 5 6 7
Kevin Vernooy 0 1 2 3 4 5 6 7
Frederik J. De Lange 0 1 2 3 4 5 6 7
Albert C. van Rossum 0 1 2 3 4 5 6 7
Pierre Croisille 0 1 2 3 4 5 6 7
Patrick Clarysse 0 1 2 3 4 5 6 7
Bastiaan Geelhoed 0 1 2 3 4 5 6 7
Michiel Rienstra 0 1 2 3 4 5 6 7
Isabelle C. Van Gelder 0 1 2 3 4 5 6 7
Marc A. Vos 0 1 2 3 4 5 6 7
Cornelis P. Allaart 0 1 2 3 4 5 6 7
Maarten J. Cramer 0 1 2 3 4 5 6 7
0 Odette A. E. Salden
1 Wouter M. van Everdingen
2 Wouter M. van Everdingen , Alwin Zweerink, Cornelis P. manuscript
3 Michiel Rienstra
4 Patrick Clarysse
5 Albert C. van Rossum
6 Department of Cardiology, University Medical Centre Utrecht , Utrecht , The Netherlands
7 Maarten J. Cramer
Parameters using myocardial strain analysis may predict response to cardiac resynchronization therapy (CRT). As the agreement between currently available strain imaging modalities is unknown, three different modalities were compared. Twenty-seven CRT-candidates, prospectively included in the MARC study, underwent cardiac magnetic resonance (CMR) imaging and echocardiographic examination. Left ventricular (LV) circumferential strain was analysed with CMR tagging (CMR-TAG), CMR feature tracking (CMR-FT), and speckle tracking echocardiography (STE). Basic strain values and parameters of dyssynchrony Vol.:(011233456789)
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and discoordination obtained with CMR-FT and STE were
compared to CMR-TAG. Agreement of CMR-FT and
CMRTAG was overall fair, while agreement between STE and
CMR-TAG was often poor. For both comparisons,
agreement on discoordination parameters was highest, followed
by dyssynchrony and basic strain parameters. For
discoordination parameters, agreement on systolic stretch index was
highest, with fair intra-class correlation coefficients (ICC)
(CMR-FT: 0.58, STE: 0.55). ICC of septal systolic rebound
stretch (SRSsept) was poor (CMR-FT: 0.41, STE: 0.30).
Internal stretch factor of septal and lateral wall (ISFsep–lat) showed
fair ICC values (CMR-FT: 0.53, STE: 0.46), while the ICC
of the total LV (ISFLV) was fair for CMR-FT (0.55) and
poor for STE (ICC: 0.32). The CURE index had a fair ICC
for both comparisons (CMR-FT: 0.49, STE 0.41). Although
comparison of STE to CMR-TAG was limited by
methodological differences, agreement between CMR-FT and
CMRTAG was overall higher compared to STE and CMR-TAG.
R
RVEF
SRSsept
SSFP
SSI
STE
TE
TR
TTPmax TTPSD
CMR-FT is a potential clinical alternative for CMR-TAG
and STE, especially in the detection of discoordination in
CRT-candidates.
Onset-delay
Peak-delay
Abbreviations
AVC strain
AVC
CMR
CMR-FT
CMR-TAG
CRT
CSPAMM
CURE ICC
ISFLV
ISFsep–lat
LBBB
LV
LVEDV
LVEF
LVESV
MARC
NYHA
Strain value at aortic valve closure
Aortic valve closure
Cardiac magnetic resonance imaging
Cardiac magnetic resonance feature tracking
Cardiac magnetic resonance myocardial
tagging
Cardiac resynchronization therapy
Complementary spatial modulation of
magnetization
Circumferential uniformity ratio estimates.
Intra-class correlation coefficient
Internal stretch factor of all left ventricular
segments
Internal stretch factor of septum and lateral
wall
Left bundle branch block
Left ventricle
Left ventricular end-diastolic volume
Left ventricular ejection fraction
Left ventricular end-systolic volume
Markers of response to cardiac
resynchronization therapy
New York Heart Association
1
2
3
4
5
6
7
Department of Cardiology, and Institute for Cardiovascular
Research (ICaR-VU), VU University Medical Centre,
Amsterdam, The Netherlands
Department of Cardiology, Thoraxcenter, University
of Groningen, University Medical Centre Groningen,
Groningen, The Netherlands
Department of Cardiology, Maastricht University Medical
Centre, Maastricht, The Netherlands
Department of Cardiology, Academic Medical Centre,
Amsterdam, The Netherlands
Université Lyon, UJM-Saint-Etienne, INSA, CNRS UMR
5520, INSERM U1206, CREATIS, 42023 Saint-Etienne,
France
Department of Medical Physiology, University of Utrecht,
Utrecht, The Netherlands
Time delay between onset of shortening of septal and lateral wall Septal to lateral wall delay of time to maximal peak shortening
Correlation coefficient
Right ventricular ejection fraction.
Septal systolic rebound stretch
Steady-state free-precession
Systolic stretch index
Speckle tracking echocardiography
Echo time
Repetition time
Time to maximal peak shortening
Standard deviation if time to peak max of
all segments
Introduction
Cardiac resynchronization therapy (CRT) is an established
treatment for patients with heart failure, reduced left
ventricular (LV) ejection fraction, and a prolonged QRS caused
by a left bundle branch block (LBBB) or nonspecific
intraventricular conduction delay [ (...truncated)