Correction to: Generation and characterization of tissue-type plasminogen activator transgenic rats

Journal of Thrombosis and Thrombolysis, Dec 2017

In the original publication of the article, the sentence in “Result” section have been incorrectly published as: “Three lines of tPA Tg rats were generated and analyzed by Southern blotting to confirm the presence of the transgene in genomic DNA. When rat DNA was digested with EcoRI and hybridized to the tPA probe described in “Materials and methods”, a 1.0 kb band was detected (Fig. 1a, b). One founder line was selected because of its high copy number (about ten copies) of tPA gene and itansgene) and 4.4 kb (endogenous gene) reding appearance, body weight, hematology, and systematization.” The corrected sentence should read as: “Three lines of tPA Tg rats were generated and analyzed by Southern blotting to confirm the presence of the transgene in genomic DNA. When rat DNA was digested with EcoRI and hybridized to the tPA probe described in “Materials and methods”, a 1.0 kb band was detected (Fig. 1a, b). One founder line was selected because of its high copy number (about ten copies) of tPA gene and its lack of detectable abnormal findings, including appearance, body weight, hematology, and systematization.” The original article has been corrected.

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Correction to: Generation and characterization of tissue-type plasminogen activator transgenic rats

Journal of Thrombosis and Thrombolysis https://doi.org/10.1007/s11239 Correction to: Generation and characterization of tissue-type plasminogen activator transgenic rats Yusuke Ito 0 1 2 Kengo Noguchi 0 1 2 Yoshiyuki Morishima 0 1 2 Kyoji Yamaguchi 0 1 2 Yusuke Ito 0 1 2 0 Medical Science Department, Daiichi Sankyo Co., Ltd. , Tokyo , Japan 1 Pharmacovigilance Department, Daiichi Sankyo Co., Ltd. , Tokyo , Japan 2 Rare Disease & LCM Laboratories, Daiichi Sankyo Co., Ltd. , 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710 , Japan - In the original publication of the article, the sentence in “Result” section have been incorrectly published as: “Three lines of tPA Tg rats were generated and analyzed by Southern blotting to confirm the presence of the transgene in genomic DNA. When rat DNA was digested with EcoRI and hybridized to the tPA probe described in “Materials and methods”, a 1.0 kb band was detected (Fig. 1a, b). One founder line was selected because of its high copy number (about ten copies) of tPA gene and itansgene) and 4.4 kb (endogenous gene) reding appearance, body weight, hematology, and systematization.” The corrected sentence should read as: “Three lines of tPA Tg rats were generated and analyzed by Southern blotting to confirm the presence of the transgene in genomic DNA. When rat DNA was digested with EcoRI and hybridized to the tPA probe described in “Materials and methods”, a 1.0 kb band was detected (Fig. 1a, b). One founder line was selected because of its high copy number (about ten copies) of tPA gene and its lack of detectable abnormal findings, including appearance, body weight, hematology, and systematization.” The original article has been corrected.


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Yusuke Ito, Kengo Noguchi, Yoshiyuki Morishima, Kyoji Yamaguchi. Correction to: Generation and characterization of tissue-type plasminogen activator transgenic rats, Journal of Thrombosis and Thrombolysis, 2017, 1-1, DOI: 10.1007/s11239-017-1598-6