RE: Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a non-randomized prospective observation cohort study

International Urology and Nephrology, May 2018

Ibrahim Halil Bozkurt, Ertugrul Sefik, Ismail Basmaci, Serdar Celik

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RE: Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a non-randomized prospective observation cohort study

International Urology and Nephrology RE: Concordance of renal stone culture: PMUC, RPUC, RSC and post- PCNL sepsis-a non-randomized prospective observation cohort study Ibrahim Halil Bozkurt 0 Ertugrul Sefik 0 Ismail Basmaci 0 Serdar Celik 0 0 HSU Izmir Bozyaka Training and Research Hospital Urology Clinic , Saim Cikrikci Str. No:59, Karabaglar, Izmir , Turkey 1 Ibrahim Halil Bozkurt Conflict of interest Ibrahim Halil Bozkurt, Ismail Basmaci, Ertugrul Sefik, and Serdar Celik declares that they have no conflict of interest. Vol.:(011233456789) - Editor, We have read the paper, “Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a nonrandomized prospective observation cohort study” [ 1 ] with great interest and appreciate the work of the authors. They have tried to determine the association of post PCNL sepsis with preoperative midstream urine cultures (PMUC), renal stone cultures (RSC), and renal pelvic urine culture (RPUC). They found that 24% had positive culture, 3.2% (4/122) PMUC, 14.7% (18/122) RPUC, and 13.9% (17/122) RSC. Seven patients (5.7%) developed postoperative infectious complications. We have a few queries. The authors stated that single-dose third generation cephalosporin was used for prophylaxis. We have read from the paper of Lojanapiwat et al. [ 2 ] stating that the bacteria isolated from patients with sepsis revealed more resistance to ceftriaxone, ceftazidime, quinolones, and amoklavin-klavulonik asit, while being relatively more sensitive to amikacin, ampicillin, vancomycin, and carbapenem. And these results guided the authors to rearrange the antibiotics used in the prophylaxis. The antibiogram of the positive cultures were given as multisensitive and multiresistant in the recent paper. We kindly ask the authors what percent of these cultures were third generation cephalosporin resistant? And does it Compliance with ethical standards 1. Walton-Diaz A , Vinay JI , Barahona J et al ( 2017 ) Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a non-randomized prospective observation cohort study . Int Urol Nephrol 49 : 31 - 35 2. Lojanapiwat B , Kitirattrakarn P ( 2011 ) Role of preoperative and intraoperative factors in mediating infection complication following percutaneous nephrolithotomy . Urol Int 86 : 448 - 452


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Ibrahim Halil Bozkurt, Ertugrul Sefik, Ismail Basmaci, Serdar Celik. RE: Concordance of renal stone culture: PMUC, RPUC, RSC and post-PCNL sepsis-a non-randomized prospective observation cohort study, International Urology and Nephrology, 2018, 1067-1067, DOI: 10.1007/s11255-018-1878-x