Recently added

Attitudes of orthodontists and laypersons towards tooth extractions and additional anchorage devices

Background This study investigated the attitudes of orthodontists and laypersons towards the choice of extracting second premolars, rather than first premolars, based on tooth condition and the use of additional anchorage devices. Methods Questionnaires were sent to two groups: 324 orthodontists who were members of the Thai Association of Orthodontists, and 100 randomly selected ...

Influence of Heat Treatment on the Surface Structure of 6082 Al Alloys

The β-Al5FeSi intermetallic phase and coarse Mg2Si particles have negative effects on extrudability and workability of 6xxx Al alloys billets. To achieve extruded products with a high surface quality, the as-cast billets are heat-treated before extrusion. During heat treatment, the undesired intermetallic particles, i.e., β-AlFeSi platelets are transformed to rounded α-Al(FeMn)Si ...

The weakening effect of soluble epoxide hydrolase inhibitor AUDA on febrile response to lipopolysaccharide and turpentine in rat

A still growing body of evidence suggests the importance of epoxyeicosatrienoic acids (EETs) in the regulation of inflammatory response; therefore, drugs that stabilize their levels by targeting the soluble epoxide hydrolase (sEH), an enzyme responsible for their metabolism, are currently under investigation. The effect of sEH inhibitors on molecular components of fever mechanism, ...

OnabotulinumtoxinA injections in chronic migraine, targeted to sites of pericranial myofascial pain: an observational, open label, real-life cohort study

Background OnabotulinumtoxinA has proven its efficacy in reducing the number of headache days in chronic migraine (CM) patients. The usual paradigm includes 31 pericranial injection sites with low dose (5 U) per site. The aim of this study is to present the results obtained using a simpler injection protocol of onabotulinumtoxinA, with injection sites targeted to pericranial ...

The rate and stability of mandibular block bone graft in recent 5 years

Background The purposes of the present study were to compare implant stabilities of mandibular block bone graft and bovine bone graft and to evaluate influencing factors for implant stability in mandibular block bone (MBB) graft. Methods This retrospective study investigated 1224 cases and 389 patients treated by one surgeon in the Department of Oral and Maxillofacial Surgery of ...

Double-Injected Human Stem Cells Enhance Rehabilitation in TBI Mice Via Modulation of Survival and Inflammation

Traumatic brain injury (TBI), a complicated form of brain damage, is a major cause of mortality in adults. Following mechanical and structural primary insults, a battery of secondary insults, including neurotransmitter-mediated cytotoxicity, dysregulation of calcium and macromolecule homeostasis, and increased oxidative stress, exacerbate brain injury and functional deficits. ...

Egress Efficacy of Persons with Multiple Sclerosis During Simulated Evacuations

Expedited evacuation of commercial and residential structures in the event of an emergency may be more difficult for persons with physical movement disorders. There is a need to better characterize the impact of such disorders and provide movement data to improve evacuee and responder safety. We undertook a pilot, feasibility study that investigated the ability of persons with ...

Neisseria lactamica Y92–1009 complete genome sequence

We present the high quality, complete genome assembly of Neisseria lactamica Y92–1009 used to manufacture an outer membrane vesicle (OMV)-based vaccine, and a member of the Neisseria genus. The strain is available on request from the Public Health England Meningococcal Reference Unit. This Gram negative, dipplococcoid bacterium is an organism of worldwide clinical interest because ...

Effects of deoxynivalenol (DON) and its microbial biotransformation product deepoxy-deoxynivalenol (DOM-1) on a trout, pig, mouse, and human cell line

Deoxynivalenol (DON), a trichothecene produced by various Fusarium species, is one of the most prevalent food- and feed-associated mycotoxins. The effects of DON and deepoxy-deoxynivalenol (DOM-1) were assessed in five different cell lines from different tissues and species starting from the first line of defense, the trout gill (RTgill-W1) and pig intestinal cells (IPEC-1 and ...

Clothes as Expression of Action in Former Concentration Camps

The prisoners of the former concentrations camps were supposed to be deprived of their socialization by brutal dehumanization. Among other things, the use of blue-and-white striped prison clothes was meant to reinforce a homogeneous and uniform prisoner society. However, studies from a sociological perspective have shown that prisoners’ societies were indeed diverse and structured, ...

The societal impact of the emerging quantum technologies: a renewed urgency to make quantum theory understandable

This paper introduces the special issue The societal impact of the emerging quantum technologies as a contribution to a more inclusive societal debate on quantum technologies. It brings together five contributions. Three are authored by quantum technology researchers who give explorations of the possible impacts of quantum technologies on science, industry and society. The fourth ...

Explicit and tacit knowledge conversion effects, in software engineering undergraduate students

This study evaluates the effect of conversion between tacit and explicit knowledge, and its influence on Software engineering and Software Process Improvement in the context of a small school software company in which undergraduate students participate as personnel. A survey measurement instrument was applied to the last three generations of students. The effect was measured from ...

Victimization Mediates the Longitudinal Association Between Depressive Symptoms and Violent Behaviors in Adolescence

Despite evidence of a positive link between depressive symptoms and violent behaviors, the pathways underlying this longitudinal association remain unknown. Depressive symptoms might drive and reinforce victimization which in turn could increase risk of individuals becoming violent towards others. Thus, we tested whether victimization mediated the link between depressive symptoms ...

The genome of the cotton bacterial blight pathogen Xanthomonas citri pv. malvacearum strain MSCT1

Xanthomonas citri pv. malvacearum is a major pathogen of cotton, Gossypium hirsutum L.. In this study we report the complete genome of the X. citri pv. malvacearum strain MSCT1 assembled from long read DNA sequencing technology. The MSCT1 genome is the first X. citri pv. malvacearum genome with complete coding regions for X. citri pv. malvacearum transcriptional activator-like ...

Geographical Distances Between Separated Parents: A Longitudinal Analysis

Using detailed geocoded microdata from the British Household Panel Survey and longitudinal random-effects models, we analyse the determinants and trajectories of geographical distances between separated parents. Findings of particular note include the following: (1) post-separation linked lives, proximities and spatial constraints are characterised by important gender asymmetries; ...

A new key player in VEGF-dependent angiogenesis in human hepatocellular carcinoma: dimethylarginine dimethylaminohydrolase 1

Background Anti-angiogenic therapies, targeting VEGF, are a promising treatment for hepatocellular carcinoma (HCC). To enhance this potential therapy, identification of novel targets in this pathway is of major interest. Nitric oxide (NO) plays a crucial role in VEGF-dependent angiogenesis. NO production depends on arginine as substrate and asymmetric dimethylarginine (ADMA) as ...

Detection of Verticillium species in Swedish soils using real-time PCR

Verticillium species are soilborne plant pathogens, responsible for big yield losses worldwide. Here, we report improved procedures to generate DNA from Verticillium species imbedded in farm soils. Using new genomic sequence information, primers for V. dahliae, V. albo-atrum, V. tricorpus, and V. longisporum were designed. In a survey of 429 samples from intensively farmed soil of ...