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Seawater drowning-associated pneumonia: a 10-year descriptive cohort in intensive care unit

Background Pneumonia is one of the major complications of drowning, but the optimal empirical antibiotic treatment is not clearly defined. Multidrug-resistant (MDR) bacteria and fungi have been identified in a recent series of freshwater drowning-associated pneumonia. However, microbial data in seawater drowning are scarce. The objective of the study is to describe the ...

Nanoscale Observation of Dehydration Process in PHEMA Hydrogel Structure

One of the most important field of interest in respect to hydrogel materials is their capability to water storage. The problem mentioned above plays an important role regarding to diffusion of fluid media containing nanoparticles, what is very useful in biomedical applications, such as artificial polymeric implants, drug delivery systems or tissue engineering. In presented work, ...

Anaemia control and the interpretation of biochemical tests for iron status in children

Background Anaemia is one of the world’s most prevalent child health problems. Its control in Africa and other developing nations has been hindered by uncertainty regarding its cause. Anaemia control has been particularly problematic in regions where the non-iron deficiency causes of anaemia, are projected to be substantial. The implementation of effective interventions to reduce ...

The crosstalk between vascular MSCs and inflammatory mediators determines the pro-calcific remodelling of human atherosclerotic aneurysm

Background Human mesenchymal stem cells (MSCs) possess well-known reparative abilities, but any defect of the immunomodulatory activity and/or the differentiation process may determine the development of human diseases, including those affecting the vascular wall. MSCs residing within the human aortic wall represent a potential cell mediator of atherosclerotic aneurysm development. ...

Review of Denitrogenation of Algae Biocrude Produced by Hydrothermal Liquefaction

Recently, algae biocrude has drawn considerable attention as algae are considered to be one of the major fuel feedstocks of the future. Based on some impressive results achieved under appropriate conditions, the algae hydrothermal liquefaction (HTL) process has proven to be energy efficient. However, the HTL of biocrude is characterized by a high nitrogen content, which prevents ...

Comparison of CSF markers and semi-quantitative amyloid PET in Alzheimer’s disease diagnosis and in cognitive impairment prognosis using the ADNI-2 database

Background The relative performance of semi-quantitative amyloid positron emission tomography (PET) and cerebrospinal fluid (CSF) markers in diagnosing Alzheimer’s disease (AD) and predicting the cognitive evolution of patients with mild cognitive impairment (MCI) is still debated. Methods Subjects from the Alzheimer’s Disease Neuroimaging Initiative 2 with complete baseline ...

Crystal Orientation Effect on the Subsurface Deformation of Monocrystalline Germanium in Nanometric Cutting

Molecular dynamics simulations of nanometric cutting on monocrystalline germanium are conducted to investigate the subsurface deformation during and after nanometric cutting. The continuous random network model of amorphous germanium is established by molecular dynamics simulation, and its characteristic parameters are extracted to compare with those of the machined deformed layer. ...

‘De tijd van folderen is voorbij’

Wat worden de Haagse speerpunten voor wat betreft de zorg de komende jaren? Waar er van december tot 15 maart om het hardst werd geroepen welke maatregelen de volgende minister van VWS zou moeten nemen, is het sinds die datum oorverdovend stil aan het Binnenhof. De tijd van folderen is voorbij.

Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypes

Background The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the inability to study complex signaling networks in patient tumors. Here, pathway-specific genomic signatures were used to interrogate GFRN ...

Fostering incidental experiences of nature through green infrastructure planning

Concern for a diminished human experience of nature and subsequent decreased human well-being is addressed via a consideration of green infrastructure’s potential to facilitate unplanned or incidental nature experience. Incidental nature experience is conceptualized and illustrated in order to consider this seldom addressed aspect of human interaction with nature in green ...

Structural Variety and Adsorptive Properties of Mesoporous Silicas with Immobilized Oligosaccharide Groups

In this research, we report on the synthesis of mesoporous silicas with various quantities of immobilized oligosaccharide groups and different pore ordering degree. The hydrothermal co-condensation of tetraethyl orthosilicate and β-cyclodextrin-containing organosilane in the presence of cetyltrimethylammonium bromide template was employed. The purpose of this investigation was to ...

Cognitive changes in alcohol-induced psychotic disorder

Aims This study aimed to explore the neuro-cognitive deficits of alcohol-induced psychotic disorder as compared to the cognitive deficits of uncomplicated alcohol dependence. Methods Participants were recruited from the acute psychiatric admission wards of the Department of Psychiatry, University of Stellenbosch and Stikland and Tygerberg Academic Hospitals in the Western-Cape, ...

The Missing Link! A New Skeleton for Evolutionary Multi-agent Systems in Erlang

Evolutionary multi-agent systems (EMAS) play a critical role in many artificial intelligence applications that are in use today. In this paper, we present a new generic skeleton in Erlang for parallel EMAS computations. The skeleton enables us to capture a wide variety of concrete evolutionary computations that can exploit the same underlying parallel implementation. We demonstrate ...

The effect of adipose tissue-derived stem cells in a middle cerebral artery occlusion stroke model depends on their engraftment rate

Background In the field of experimental stem cell therapy, intra-arterial (IA) delivery yields the best results concerning, for example, migrated cell number at the targeted site. However, IA application also appears to be associated with increased mortality rates and infarction. Since many rodent studies systemically apply 1 × 106 cells, this could also be a consequence of ...

Nanoporous Cyanate Ester Resins: Structure-Gas Transport Property Relationships

This contribution addresses the relationships between the structure and gas transport properties of nanoporous thermostable cyanate ester resins (CERs) derived from polycyclotrimerization of 1,1′-bis(4-cyanatophenyl)ethane in the presence of 30 or 50 wt% of inert high-boiling temperature porogens (i.e., dimethyl- or dibutyl phthalates), followed by their quantitative removal. The ...

Memory is preserved in older adults taking AT1 receptor blockers

Background Prior work suggests that some but not all antihypertensive treatments may benefit cognition and risk for Alzheimer’s disease, independent of stroke. Angiotensin II receptor blockers (ARBs) have been highlighted as one antihypertensive drug class that may confer greatest benefit. Methods The participants comprised 1626 nondemented adults, aged 55–91 years, recruited from ...

Carbon isotopic fractionation during vaporization of low molecular weight hydrocarbons (C6–C12)

Three series of laboratory vaporization experiments were conducted to investigate the carbon isotope fractionation of low molecular weight hydrocarbons (LMWHs) during their progressive vaporization. In addition to the analysis of a synthetic oil mixture, individual compounds were also studied either as pure single phases or mixed with soil. This allowed influences of mixing effects ...

Saskia Capello

“Elf jaar geleden liep ik door een paardrij-ongeluk een gecompliceerde enkelbreuk op. Om te revalideren, ging ik fietsen. Dat beviel zo goed dat ik het paard de deur uit heb gedaan en nu een schuur vol fietsen heb. Ik beoefen bijna alle disciplines: wielrennen op de weg, mountainbiken en fietsen op de baan. Dat doe ik op de baan in Apeldoorn, vlakbij waar ik woon.”

In Situ Analysis of Oxygen Vacancies and Band Alignment in HfO2/TiN Structure for CMOS Applications

The density of oxygen vacancies characterization in high-k/metal gate is significant for semiconductor device fabrication. In this work, a new approach was demonstrated to detect the density of oxygen vacancies by in situ x-ray photoelectron spectroscopy (XPS) and ultraviolet photoelectron spectroscopy (UPS) measurement. Moreover, the band alignment of the structure with optical ...

Sensitivity of the overturning circulation of the Baltic Sea to climate change, a numerical experiment

An ocean model covering the Baltic Sea area is forced by several climate scenarios for a period extending from 1961 to 2100. The Baltic Sea overturning circulation is then analyzed. The analysis shows that this circulation decreases between the end of the 20th century and the end of the 21st century, and that the decrease is amplified in the case of the strongest greenhouse gas ...

Anticonvulsant effects of antiaris toxicaria aqueous extract: investigation using animal models of temporal lobe epilepsy

Background Antiaris toxicaria has previously shown anticonvulsant activity in acute animal models of epilepsy. The aqueous extract (AAE) was further investigated for activity in kindling with pentylenetetrazole and administration of pilocarpine and kainic acid which mimic temporal lobe epilepsy in various animal species. Results ICR mice and Sprague–Dawley rats were pre-treated ...

The 116G > A MSH6 and IVS1-1121C > T PMS2 Genes Polymorphisms Modulate the Risk of the Sporadic Colorectal Cancer Development in Polish Population

Colorectal cancer (CRC) is one of the most common cancers worldwide. DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects mismatches generated during DNA replication. MMR defects were found to be associated with hereditary non-polyposis colorectal cancer (HNPCC) and a subset of sporadic colon cancers. The inheritance of common variations in MMR genes may ...

Shape and Size-Dependent Magnetic Properties of Fe3O4 Nanoparticles Synthesized Using Piperidine

In this article, we proposed a facile one-step synthesis of Fe3O4 nanoparticles of different shapes and sizes by co-precipitation of FeCl2 with piperidine. A careful investigation of TEM micrographs shows that the shape and size of nanoparticles can be tuned by varying the molarity of piperidine. XRD patterns match the standard phase of the spinal structure of Fe3O4 which confirms ...