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Integrated omics and gene expression analysis identifies the loss of metabolite–metabolite correlations in small cell lung cancer

Integrated omics and gene expression analysis identifies the loss of metabolite-metabolite correlations in small cell lung cancer Li Yu,1 Kefeng Li,2 Zhaoguo Xu,1 Guoyuan Cui,1 Xiaoye Zhang1 1Department of Oncology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China; 2School of Medicine, University of California–San Diego, San Diego, CA, USA Background and...

Right- and left-sided stage III colon cancers present different prognostic outcomes of oxaliplatin-based adjuvant chemotherapy after curative resection

Right- and left-sided stage III colon cancers present different prognostic outcomes of oxaliplatin-based adjuvant chemotherapy after curative resection Jianhong Peng,1,* Cong Li,1,* Fulong Wang,1 Huizhong Zhang,2 Weiwei Xiao,3 Hui Li,4 Zhenhai Lu,1 Zhizhong Pan,1 Xiaojun Wu,1 Rongxin Zhang1 1Department of Colorectal Surgery, Sun Yat-sen University Cancer Center, State Key...

B[e] stars. I. HD 51585 (=OY Gem)

We analyse CCD spectroscopic material obtained at the Haute Provence Observatory between 1990 and 1993, covering the wavelength region 3800-11000 Å. 320 emission lines were measured and identified. Of these about 40% correspond to permitted or forbidden lines of ionized iron. Many forbidden lines (20% of the total) are present, including many classic nebular lines. We also...

Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire

Quality of life in coeliac disease: qualitative interviews to develop candidate items for the Coeliac Disease Assessment Questionnaire Helen Crocker, Crispin Jenkinson, Michele Peters Health Services Research Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK Background: Coeliac-specific measures have been criticized for not complying with current...

Justice and Corporate Governance: New Insights from Rawlsian Social Contract and Sen’s Capabilities Approach

By considering what we identify as a problem inherent in the ‘nature of the firm’—the risk of abuse of authority—we propound the conception of a social contract theory of the firm which is truly Rawlsian in its inspiration. Hence, we link the social contract theory of the firm (justice at firm’s level) with the general theory of justice (justice at society’s level). Through this...

A psicologia revisitada pela pragmática: subjetividade, conhecimento e método

The goal of this paper is to discuss contributions that could result from an appropriation of the neopragmatic philosophy of language for the analysis of theoretical and methodological assumptions of Psychology, such as subjectivity, knowledge, and method. By means of a theoretical study, the concepts of representation, objectivity, and knowledge, and their relation to Psychology...

Effect of inhibition of CBP-coactivated β-catenin-mediated Wnt signalling in uremic rats with vascular calcifications

Uremic vascular calcification is a regulated cell-mediated process wherein cells in the arterial wall transdifferentiate to actively calcifying cells resulting in a process resembling bone formation. Wnt signalling is established as a major driver for vessel formation and maturation and for embryonic bone formation, and disturbed Wnt signalling might play a role in vascular...

The effective temperature scale of giant stars (F0–K5) - I. The effective temperature determination by means of the IRFM

We have applied the InfraRed Flux Method (IRFM) to a sample of approximately 500 giant stars in order to derive their effective temperatures with an internal mean accuracy of about 1.5% and a maximum uncertainty in the zero point of the order of 0.9%. For the application of the IRFM, we have used a homogeneous grid of theoretical model atmosphere flux distributions developed by...

A supplementary list of southern nearby dwarf galaxy candidates

To improve the census of the Local Volume galaxies, we carried out a systematic search for nearby dwarf galaxies in a declination range of based on the ESO/SERC film copies. As a result, we present a list of 81 nearby dwarf galaxy candidates of low surface brightness which have angular diameters . Half of the objects have been found for the first time. This sample may be...

Welfare effects of health insurance in Mexico: The case of Seguro Popular de Salud

Abstract This study contributes with original empirical evidence on the distributional and welfare effects of one of the most important health policies implemented by the Mexican government in the last decade, the Seguro Popular de Salud (SPS). We analyze the effect of SPS on households’ welfare using a decomposable index that considers insured and uninsured households’ response...

Combining solar power with coal-fired power plants, or cofiring natural gas

Coal-fired power operators continue to look for ways to increase the efficiency and extend the working lives of their plants by improving operational flexibility and reducing environmental impact. Two possible options are explored here: combining solar energy with coal-fired power generation, and cofiring natural gas in coal-fired plants. Both techniques show potential. Depending...

Coordinated responses to honey bee decline in the USA

In response to successive years of high honey bee mortality, the United States Congress mandated the US Department of Agriculture (USDA) to increase funding for research and education directed at reducing honey bee decline. The funding follows two administrative streams within USDA – one through the USDA Agricultural Research Service (ARS) and another through the USDA National...

Spectra of late type stars from 4800 to 9000 Å

We present optical spectra of 21 stars from 4800 to 8920 Å, covering essentially the late spectral types, G, K, M and the luminosity classes I and III. Half of the stars are super metal rich (SMR) ones. The spectra were obtained at a resolution of 1.25 Å using the Aurelie spectrograph, equipped with a linear array CCD-like detector, attached to the OHP 1.52 m telescope. Also...

Analytical expressions for field astigmatism in decentered two mirror telescopes and application to the collimation of the ESO VLT

We derive formulae for all parameters defining the field astigmatism of misaligned two mirror telescopes with arbitrary geometries and with stop positions anywhere on the line connecting the vertices of the two mirrors. The formulae show explicitly the dependence of the field astigmatism on the fundamental design parameters and characteristics of the telescope and on the stop...

Transition probabilities for forbidden lines of Fe III

Radiative transition probabilities have been calculated for states within the 3d6 configuration of Fe III. Magnetic dipole (M1) and electric quadrupole (E2) transition probabilities have been obtained using average energies, electrostatic and spin-orbit integrals adjusted so as to fit the observed energy levels. The most important configuration interaction (CI) and relativistic...

Hybridization and backcrossing between transgenic oilseed rape and two related weed species under field conditions

Determining the frequency of crop-wild transgene flow under field conditions is a necessity for the development of regulatory strategies to manage transgenic hybrids. Gene flow of green fluorescent protein (GFP) and Bacillus thuringiensis (Bt) transgenes was quantified in three field experiments using eleven independent transformed Brassica napus L. lines and the wild relatives...

Performance comparison of the cobas Liat and Cepheid GeneXpert systems for Clostridium difficile detection

Clostridium difficile infection (CDI) is a high burden and significant cause of healthcare-acquired infectious diarrhea in the United States (US). Timely and accurate diagnosis of CDI enables the rapid initiation of antibiotic therapy and infection control policies to minimize disease transmission. Polymerase chain reaction (PCR) assays have become a preferred modality for...