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Barriers and facilitators for BIM use among Swedish medium-sized contractors - “We wait until someone tells us to use it”

Background The pace of diffusion of BIM (Building Information Modelling) use is considered to increase with governmental initiatives in which public clients in countries like Finland, Singapore, United Kingdom, and Sweden begin requiring BIM as a part of the project delivery. Currently, larger contractor firms use BIM to a certain extent. However, BIM use by mid-sized contractor ...

Genome-wide Association Analysis Tracks Bacterial Leaf Blight Resistance Loci In Rice Diverse Germplasm

Background A range of resistance loci against different races of Xanthomonas oryzae pv. oryzae (Xoo), the pathogen causing bacterial blight (BB) disease of rice, have been discovered and characterized. Several have been deployed in modern varieties, however, due to rapid evolution of Xoo, a number have already become ineffective. The continuous “arms race” between Xoo and rice ...

Biologische Mechanismen der Strahlenwirkung

Hintergrund Eine Exposition mit ionisierender Strahlung für diagnostische Zwecke ist in der modernen Medizin unumgänglich. Bei einer Tumorerkrankung ist die therapeutische Anwendung dieser Strahlung hoch effektiv. Dies impliziert immer eine Exposition normaler Gewebestrukturen mit signifikanten Strahlendosen. Die diagnostische oder therapeutische Exposition mit ionisierender ...

Comparison of response patterns in different survey designs: a longitudinal panel with mixed-mode and online-only design

Background Increasing availability of the Internet allows using only online data collection for more epidemiological studies. We compare response patterns in a population-based health survey using two survey designs: mixed-mode (choice between paper-and-pencil and online questionnaires) and online-only design (without choice). Methods We used data from a longitudinal panel, the ...

Anxiety Levels in Children with Autism Spectrum Disorder: A Meta-Analysis

The aim of the current study was to meta-analytically examine whether anxiety levels in children with autism spectrum disorders (ASD) are elevated. A total of 83 articles were selected from a systematic literature search and were included in the meta-analyses. Results demonstrated that children with ASD had higher anxiety levels compared to typically developing children, and this ...

Doe het veilig, denk eerst even na

In de rubriek Geregeld leggen wij het vergrootglas op wet- en regelgeving. Mr. Alice Broersma verheldert onderwerpen die voor niet-juristen soms taaie kost zijn, of bespreekt juridische thema’s die actueel zijn in ons werkveld.

Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women

Background Tubulointerstitial nephritis antigen-like 1 protein (TINAGL1), is a matricellular protein, known to play role in cell adhesion and cell receptor interaction. Research related to TINAGL1 is limited to cell culture and animal models. Demonstration of TINAGL1 as a positive regulator of angiogenesis and its expression in the decidua of postimplantation mouse uterus, prompted ...

Microscopic and ultrastructural evidences in human skin following calcium hydroxylapatite filler treatment

This study uses light and electron microscopes to gain a better knowledge of the interactions of calcium hydroxylapatite filler with the connective tissue of the skin and the modifications of the human deep dermis, after 2 months of treatment. Some morphological evidences of this observational study of filler treated tissue support-specific mechanism involved in the structural ...

The influence of sex and diet on the characteristics of hibernation in Syrian hamsters

Research on deep hibernators almost exclusively uses species captured from the wild or from local breeding. An exception is Syrian hamster (Mesocricetus auratus), the only standard laboratory animal showing deep hibernation. In deep hibernators, several factors influence hibernation quality, including body mass, sex and diet. We examined hibernation quality in commercially obtained ...

Thermo-responsive graphene dispersions by liquid phase exfoliation of graphite aided by an alkylated Percec monodendron

Large-scale production of graphene and subsequent sample engineering is the key for fully-realizing the potential applications proposed to this intriguing two-dimensional nanomaterial. Herein, smart graphene dispersions with low defects and thermo-responsive properties can be obtained by liquid phase exfoliation of graphite using an alkylated Percec monodendron ...

Data completion in building information management: electrical lines from range scans and photographs

Background The concept of building information management (BIM) is based on its holistic nature. This idea pays off, if all relevant information is fused into one consistent data set. As a consequence, the completeness of data is vital and the research question on how to complete data automatically remains open. Methods In this article we present a data completion technique based ...

Perceptions of neighborhood environments and their association with overweight in children, adolescents, and caretakers in a medium-sized city in Brazil

Background Previous studies conducted in developed countries have suggested associations between perceptions of neighborhood characteristics and weight gain. However, there are few studies regarding the adult perception of the residential environment and overweight in children and adolescents in countries with low and medium income. The aim of the study was to assess the ...

Big data for secure healthcare system: a conceptual design

The concept of big data is now treated from different points of view covering its implications in many fields remarkably including healthcare. To achieve the wealth of health information, integrating, sharing and availing data are the essential tasks that ultimately demand the concept of distributed system. However, privacy and security of data are the matter of concern, as data ...

Impingement-Syndrom des oberen Sprunggelenks

Das Impingement-Syndrom des oberen Sprunggelenks (OSG) ist eine klinische Diagnose und entsteht posttraumatisch, überlastungsbedingt durch wiederholte mechanische Belastungen oder durch anatomische Varianten. Es zeichnet sich durch chronisch-rezidivierende Schmerzen und/oder einen eingeschränkten Bewegungsumfang aus. Aufgrund eines pathologischen Engpasses werden Knochen- und/oder ...

The micro-politics of small-scale fisheries governance in South Africa: a case study of community-based political representation as a form of brokerage

The right of small-scale fishers to participate in governance and management processes has been increasingly recognised by theorists and policy-makers over the last thirty years. Political representation is central to the realisation of the right to participation. In the context of small-scale fisheries, the first level of political representation is usually located within a ...

Lusutrombopag increases hematocytes in a compensated liver cirrhosis patient

A 56-year-old Japanese man with liver cirrhosis (LC) due to hepatitis C virus was admitted to our hospital for radiofrequency ablation of residual tumor following lusutrombopag administration. Laboratory tests revealed thrombocytopenia and leukopenia. The patient’s LC was managed, and he was classified as Child–Pugh A. After admission, lusutrombopag was administered for 7 days. The ...

The FAST D protocol: a simple method to rule out traumatic vascular injuries of the lower extremities

Background The aim of this study is to assess the accuracy of a Fast Doppler protocol for the examination of an injured lower limb, namely 2-Point Fast Doppler (2PFD), in order to rapidly triage arterial lesions after penetrating trauma. Methods The presence of flow and the aspects of the Doppler waveform of the dorsalis pedis artery (DPA) and posterior tibial artery (PTA) of the ...

Detection of tetrabromobisphenol A and its mono- and dimethyl derivatives in fish, sediment and suspended particulate matter from European freshwaters and estuaries

An analytical method was developed for the determination of tetrabromobisphenol A (TBBPA), 3,3′,5,5′-tetrabromobisphenol-A-monomethyl ether (MM-TBBPA) and 3,3′,5,5′-tetrabromobisphenol-A-dimethyl ether (DM-TBBPA), and its valid application on fish muscle matrix (bream and sole), suspended particulate matter (SPM) and surface sediment layer samples, using only 0.5 g sample material, ...

Instrumental approach toward understanding nano-pollutants

Nano-pollutants (NPLTs) have recently raised global concerns due to their possible harmful impact on environment and human health. However, until date, information on the occurrence, fate and toxicity of NPLTs in environment is scant. The knowledge gap can be attributed to the lack of advanced and sophisticated methodologies for the precise detection and characterization of NPLTs ...

Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia

Background Despite their huge epidemiological impact, primary headaches, trigeminal neuralgia and other chronic pain conditions still receive suboptimal medical approach, even in developed countries. The limited efficacy of current pain-killers and prophylactic treatments stands among the main reasons for this phenomenon. Botulinum neurotoxin (BoNT) represents a well-established ...

Autobiographical memory loss following a right prefrontal lobe tumour resection: a case report and review of the literature

Introduction The right prefrontal lobe has not traditionally been considered eloquent brain. Resection of tumours within this region does not typically lead to permanent functional impairment. In this report, we highlight the case of a patient who developed autobiographical memory loss following an uncomplicated resection of a right prefrontal tumour. Case material A previously fit ...

In situ electrochemically converting Fe2O3-Ni(OH)2 to NiFe2O4-NiOOH: a highly efficient electrocatalyst towards water oxidation

To develop low-cost, earth-abundant NiFebased materials as highly efficient oxygen evolution reaction (OER) electrocatalysts and to probe new catalytic species are still great challenges to now. Here, an in situ formation of OER active NiFe2O4-NiOOH nanosheet arrays is demonstrated as a highly efficient OER electrocatalyst by the anodization of Fe2O3 domains anchored on Ni(OH)2 ...

Revisiting CDK Inhibitors for Treatment of Glioblastoma Multiforme

Despite extensive efforts and continual progress in research and medicine, outcomes for patients with high-grade glioma remain exceptionally poor. Over the past decade, research has revealed a great deal about the complex biology behind glioma development, and has brought to light some of the major barriers preventing successful treatment. Glioblastoma multiforme (GBM) (stage 4 ...