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Identification of N-Terminally Truncated Derivatives of Insulin Analogs Formed in Pharmaceutical Formulations

PurposeIsolation and identification of unknown impurities of recombinant insulin lispro (produced at IBA) formed during accelerated stability testing of pharmaceutical solutions. For comparative purposes also commercially available formulations of recombinant human insulin (Humulin S®; Lilly), recombinant insulin lispro (Humalog®; Lilly), recombinant insulin aspart (NovoRapid...

An enhanced sum rate in the cluster based cognitive radio relay network using the sequential approach for the future Internet of Things

The cognitive radio relay plays a vital role in cognitive radio networking (CRN), as it can improve the cognitive sum rate, extend the coverage, and improve the spectral efficiency. However, cognitive relay aided CRNs cannot obtain a maximal sum rate, when the existing sensing approach is applied to a CRN. In this paper, we present an enhanced sum rate in the cluster based...

Sonographic Evaluation of Umbilical Vein

To evaluate intraabdominal course of umbilical vein, its relation with portal vein and ductus venosus and its anomalies. All pregnant women were examined during midtrimester anomaly scan between January 2015 and December 2017. With evaluation of umbilical vein in its intraabdominal course, size of umbilical vein, its relation to the stomach and the gallbladder and origin of...

Infrastructure and long-run economic growth: evidence from Chinese provinces

This paper attempts to shed empirical light on one of the oldest debates in the literature on infrastructure—whether infrastructure capital contributes to aggregate output in the long run, and related to that, whether investing in infrastructure is an effective tool to promote regional development. Drawing from a panel data set of 29 Chinese provinces over the period 1985–2012...

Biological control of weeds: an analysis of introductions, rates of establishment and estimates of success, worldwide

The foremost document that comprehensively reports on biological control introductions against weeds—‘Biological control of weeds: a world catalogue of agents and their target weeds’—has been updated and now includes all deliberate releases made through 2012. It includes data on 1555 intentional releases of 468 biological control agent species used against 175 species of target...

Quasi-Static and Dynamic Behaviors of Helical Gear System with Manufacturing Errors

Time-varying mesh stiffness (TVMS) and gear errors include short-term and long-term components are the two main internal dynamic excitations for gear transmission. The coupling relationship between the two factors is usually neglected in the traditional quasi-static and dynamic behaviors analysis of gear system. This paper investigates the influence of short-term and long-term...

Oil Consumption in Transport and Economic Growth Nexus: Empirical Evidence from Cameroon

This paper focuses on casting light on the causal relationship between oil consumption in transport and economic growth in Cameroon. This paper uses an annual data covering the period 1975-2014, which is a five-step modern time series techniques. They include the Unit root tests, co-integration analysis, and Granger-causality based on error correction model. As a robustness test...

Analysis of errors made on in utero MR studies of the foetal brain in the MERIDIAN study

ObjectivesIn utero magnetic resonance (iuMR) imaging to diagnose foetal brain abnormalities has been established and is supported by meta-analyses of retrospective and prospective studies. In this paper we describe and classify the iuMR errors made in the largest diagnostic accuracy study to date (MERIDIAN). We also correlate the error rates and types with the prior experience of...

Significant Enhancement of MgZnO Metal-Semiconductor-Metal Photodetectors via Coupling with Pt Nanoparticle Surface Plasmons

We proposed and demonstrated MgZnO metal-semiconductor-metal (MSM) ultraviolet photodetectors (UV) assisted with surface plasmons (SPs) prepared by the radio frequency magnetron sputtering deposition method. After the decoration of their surface with Pt nanoparticles (NPs), the responsivity of all the electrode spacing (3, 5, and 8 μm) photodetectors were enhanced dramatically...

A comparison of drinking behavior using a harmonized methodology (Liq.In 7 ) in six countries

PurposeTo assess drinking occasions (volume and type) according to consumption with food in or outside meals, and location, for six countries.MethodsA total of 10,521 participants aged 4–65 years from Argentina, Brazil, China, Indonesia, Mexico and Uruguay completed a validated 7-day fluid intake record. For each drinking event, the volume consumed, the fluid type, the location...

Indirect questioning method reveals hidden support for female genital cutting in South Central Ethiopia

Female genital cutting (FGC) has major implications for women’s physical, sexual and psychological health, and eliminating the practice is a key target for public health policy-makers. To date one of the main barriers to achieving this has been an inability to infer privately-held views on FGC within communities where it is prevalent. As a sensitive (and often illegal) topic...

Heterogeneous effects in the international transmission of the US monetary policy: a factor-augmented VAR perspective

This paper analyses the international transmission of US monetary policy shocks. We use a time-varying, factor-augmented VAR framework to examine how and to what extent the propagation of US policy shocks affects the South East Asian (SEA) and European Union (EU) economies, through various transmission channels. We find that in the SEA economies, the income absorption effect is...

Detecting the contagion effect in mass killings; a constructive example of the statistical advantages of unbinned likelihood methods

Background When attempting to statistically distinguish between a null and an alternative hypothesis, many researchers in the life and social sciences turn to binned statistical analysis methods, or methods that are simply based on the moments of a distribution (such as the mean, and variance). These methods have the advantage of simplicity of implementation, and simplicity of...

Thermal Stability of Latex Modified Mortars Containing CNTs

Durability of concrete and cementitious materials has been of a great concern to the construction industry in the last two decades due to the deterioration of large number of concrete structures which were built in the 60 and 70 s. Among different environmental conditions, the continuous exposure to freeze–thaw and thermal fatigue cycles remains one of the most aggressive...

Assessing causal links in fish stock–recruitment relationships

Understanding whether recruitment fluctuations in fish stock arise from stochastic forcing (e.g. environmental variations) rather than deterministic forces (e.g. intrinsic dynamics) is a long standing question with important applied consequences for fisheries ecology. In particular, the relationship between recruitment, spawning stock biomass and environmental factors is still...

Checkpointinhibition beim Lungenkarzinom langfristig wirksam

Intensiv vorbehandelte Patienten mit nichtkleinzelligem Lungenkrebs (NSCLC) profitieren auch langfristig von der Nivolumab-Therapie.

Structure, mechanical properties and surface morphology of the snapping shrimp claw

The snapping shrimp preys by rapidly closing its snapping claw to generate a fast water jet, creating a shockwave that bombards the nearby prey and other shrimp. This behaviour has led to considerable interest and research. However, the structure, surface morphology and mechanical properties of the snapping claw are unreported. We used a combination of techniques including...