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Probiotics for vaginal health in South Africa: what is on retailers’ shelves?

Background Probiotics are widely used to improve gastrointestinal (GI) health, but they may also be useful to prevent or treat gynaecological disorders, including bacterial vaginosis (BV) and candidiasis. BV prevalence is high in South Africa and is associated with increased HIV risk and pregnancy complications. We aimed to assess the availability of probiotics for vaginal health ...

Relationship between the presence of baccalaureate-educated RNs and quality of care: a cross-sectional study in Dutch long-term care facilities

Background Recent evidence suggests that an increase in baccalaureate-educated registered nurses (BRNs) leads to better quality of care in hospitals. For geriatric long-term care facilities such as nursing homes, this relationship is less clear. Most studies assessing the relationship between nurse staffing and quality of care in long-term care facilities are US-based, and only a ...

Next-to-leading order prediction for the decay \( \mu \to e\kern0.22em \left({e}^{+}{e}^{-}\right)\;\nu \kern0.2em \overline{\nu} \)

We present the differential decay rates and the branching ratios of the muon decay with internal conversion, \( \mu \to e\kern0.22em \left({e}^{+}{e}^{-}\right)\;\nu \kern0.2em \overline{\nu} \), in the Standard Model at next-to-leading order (NLO) in the on-shell scheme. This rare decay mode of the muon is among the main sources of background to the search for μ → eee decay. We ...

Treino Das Funções Executivas em Idosos: Uma Revisão Sistemática da Literatura.

ResumoAs Funções Executivas (FE) são altamente sensíveis aos efeitos do envelhecimento humano. Este estudo de revisão sistemática teve como objetivo realizar buscas de artigos nas palavras-chave relacionados com treino das funções executivas em idosos. Os artigos indexados em bases de dados internacionais foram pesquisados e analisados. Os descritores foram: “training executive ...

A novel, putatively null, FGD1 variant leading to Aarskog-Scott syndrome in a family from UAE

Background The X-linked condition “Aarskog-Scott syndrome (AAS)” causes a characteristic combination of short stature, facial, genital and skeletal anomalies. Studies elucidated a causative link between AAS and mutations in the FGD1 gene, which encodes a Rho/Rac guanine exchange factor. FGD1 is involved in regulating signaling pathways that control cytoskeleton organization and ...

Food-specific sublingual immunotherapy is well tolerated and safe in healthy dogs: a blind, randomized, placebo-controlled study

Background Food allergies are increasing in prevalence but no treatment strategies are currently available to cure dogs with food allergy. Over the past decade, experimental food allergen-specific sublingual immunotherapy (FA-SLIT) has emerged as a potential treatment for food allergies in human medicine. However, FA-SLIT has not been investigated in dogs. Therefore, the objective ...

Sistemas Neuro-Moleculares necesarios para el proceso de memoria

Resumen Desde el punto de vista evolutivo, el proceso de la memoria se desarrolló a nivel cognitivo sobre todo en los mamíferos, como necesidad para concebir el futuro, empleando elementos conocidos con el fin de responder al ambiente, de ahí su relación tan estrecha con otros procesos como el aprendizaje, el sueño, el movimiento y la atención, pues los recuerdos se crean con fines ...

Influenza epidemic surveillance and prediction based on electronic health record data from an out-of-hours general practitioner cooperative: model development and validation on 2003–2015 data

Background Annual influenza epidemics significantly burden health care. Anticipating them allows for timely preparation. The Scientific Institute of Public Health in Belgium (WIV-ISP) monitors the incidence of influenza and influenza-like illnesses (ILIs) and reports on a weekly basis. General practitioners working in out-of-hour cooperatives (OOH GPCs) register diagnoses of ILIs ...

Prioritizing problems in and solutions to homecare safety of people with dementia: supporting carers, streamlining care

Background Dementia care is predominantly provided by carers in home settings. We aimed to identify the priorities for homecare safety of people with dementia according to dementia health and social care professionals using a novel priority-setting method. Methods The project steering group determined the scope, the context and the criteria for prioritization. We then invited 185 ...

Genomic predictions for economically important traits in Brazilian Braford and Hereford beef cattle using true and imputed genotypes

Background Genomic selection (GS) has played an important role in cattle breeding programs. However, genotyping prices are still a challenge for implementation of GS in beef cattle and there is still a lack of information about the use of low-density Single Nucleotide Polymorphisms (SNP) chip panels for genomic predictions in breeds such as Brazilian Braford and Hereford. ...

Genetic risk score and risk of stage 3 chronic kidney disease

Background We developed a genetic risk score (GRS) and examined whether the GRS may predict incident stage 3 chronic kidney disease (CKD) independent of common clinical risk factors. Method The present study included 2,698 individuals who attended the 15th (1977 to 1979) and the 24th exams (1995 to 1998) in the Framingham Original cohort or the 6th (1995 to 1998) and the 8th exams ...

The Lookout: alta velocidad, riesgo y un cerebro sobreviviente

ResumenThe Lookout es una película que relata la vida de Chris Pratt, un excelente jugador de hockey sobre hielo, quien luego de que sufriera un daño cerebral adquirido por un traumatismo craneoencefálico, presenta un dramático cambio en su cognición y comportamiento. A lo largo del film, el personaje brinda varias escenas que permiten identificar aspectos de interés para la ...

Health literacy of recently hospitalised patients: a cross-sectional survey using the Health Literacy Questionnaire (HLQ)

Background Health literacy is simply defined as an individual’s ability to access, understand and use information in ways that promote and maintain good health. Lower health literacy has been found to be associated with increased emergency department presentations and potentially avoidable hospitalisations. This study aimed to determine the health literacy of hospital inpatients, ...

Alucinaciones visuales y funcionamiento cognitivo en pacientes con déficit visual adquirido.

ResumenLas alucinaciones visuales son síntomas comunes en diversos cuadros clínicos. En el contexto oftalmológico se ha descrito el Síndrome de Charles Bonnet (SCB), el cual se ha caracterizado por la presencia de alucinaciones visuales generalmente de tipo complejas en sujetos con déficit visual adquirido y sin patología psicológica o psiquiátrica asociada, pudiendo distinguir la ...

Solvability of a q-fractional integral equation arising in the study of an epidemic model

We study the solvability of a functional equation involving q-fractional integrals. Such an equation arises in the study of the spread of an infectious disease that does not induce permanent immunity. Our method is based on the noncompactness measure argument in a Banach algebra and an extension of Darbo’s fixed point theorem. MSC: 62P10, 26A33, 45G10.

Five-loop quark mass and field anomalous dimensions for a general gauge group

We present analytical five-loop results for the quark mass and quark field anomalous dimensions, for a general gauge group and in the \( \overline{\mathrm{MS}} \) scheme. We confirm the values known for the gauge group SU(3) from an independent calculation, and find full agreement with results available from large-N f studies.

Is there a justification for classifying GLP-1 receptor agonists as basal and prandial?

Several GLP-1 receptor agonists are currently available for treatment of type 2 diabetic patients. Based on their pharmacokinetic/pharmacodynamic profile, these drugs are classified as short-acting GLP-1 receptor agonists (exenatide and lixisenatide) or long-acting GLP-1 receptor agonists (exenatide-LAR, liraglutide, albiglutide, and dulaglutide). In clinical practice, they are ...

A two-phase approach for the identification of refugees with priority need for mental health care in Lebanon: a validation study

Background Time and resource efficient mental disorder screening mechanisms are not available to identify the growing number of refugees and other forcibly displaced persons in priority need for mental health care. The aim of this study was to identify efficient screening instruments and mechanisms for the detection of moderate and severe mental disorders in a refugee setting. ...

Medium throughput bisulfite sequencing for accurate detection of 5-methylcytosine and 5-hydroxymethylcytosine

Background Epigenetic modifications of DNA, such as 5-methylcytosine and 5-hydroxymethycytosine, play important roles in development and disease. Here, we present a cost-effective and versatile methodology for the analysis of DNA methylation in targeted genomic regions, which comprises multiplexed, PCR-based preparation of bisulfite DNA libraries followed by customized MiSeq ...

Visual analogue scales (VAS)

Backround Visual analogue scales (VAS) are psychometric measuring instruments designed to document the characteristics of disease-related symptom severity in individual patients and use this to achieve a rapid (statistically measurable and reproducible) classification of symptom severity and disease control. VAS can also be used in routine patient history taking and to monitor the ...

Multiple solutions to impulsive differential equations

In this paper, we study the existence of a second-order impulsive differential equations depending on a parameter λ. By employing a critical point theorem, the existence of at least three solutions is obtained. MSC: 34A37, 34K10.

Evaluation of the ablation margin of hepatocellular carcinoma using CEUS-CT/MR image fusion in a phantom model and in patients

Background To assess the accuracy of contrast-enhanced ultrasound (CEUS)-CT/MR image fusion in evaluating the radiofrequency ablative margin (AM) of hepatocellular carcinoma (HCC) based on a custom-made phantom model and in HCC patients. Methods Twenty-four phantoms were randomly divided into a complete ablation group (n = 6) and an incomplete ablation group (n = 18). After ...

Classical and quantum stability in putative landscapes

Landscape analyses often assume the existence of large numbers of fields, N , with all of the many couplings among these fields (subject to constraints such as local supersymmetry) selected independently and randomly from simple (say Gaussian) distributions. We point out that unitarity and perturbativity place significant constraints on behavior of couplings with N , eliminating ...

MR imaging for detection of trampoline injuries in children

Background The recreational use of trampolines is an increasingly popular activity among children and adolescents. Several studies reported about radiological findings in trampoline related injuries in children. The following publication presents our experience with MRI for detection of trampoline injuries in children. Methods 20 children (mean 9.2 years, range: 4–15 years) who had ...

Chronic physical conditions, multimorbidity and physical activity across 46 low- and middle-income countries

Background There are no nationally representative population-based studies investigating the relationship between physical activity, chronic conditions and multimorbidity (i.e., two or more chronic conditions) in low- and middle-income countries (LMICs), and studies on a multi-national level are lacking. This is an important research gap, given the rapid increase in the prevalence ...