#### Multi-nest high-resolution model of submesoscale circulation features in the Gulf of Taranto

Recent oceanographic field measurements and high-resolution numerical modelling studies have revealed intense, transient, submesoscale motions characterised by a horizontal length scale of 100–10,000 m. This submesoscale activity increases in the fall and winter when the mixed layer (ML) depth is at its maximum. In this study, the submesoscale motions associated with a large-scale ...

#### 3D fibre architecture of fibre-reinforced sand

The mechanical behaviour of fibre-reinforced sands is primarily governed by the three-dimensional fibre architecture within the sand matrix. In laboratory, the normal procedures for sample preparation of fibre-sand mixtures generally produce a distribution of fibre orientations with a preferential bedding orientation, generating strength anisotropy of the composite’s response under ...

#### Reduced Models for Ferromagnetic Thin Films with Periodic Surface Roughness

We investigate the influence of periodic surface roughness in thin ferromagnetic films on shape anisotropy and magnetization behavior inside the ferromagnet. Starting from the full micromagnetic energy and using methods of homogenization and $\Gamma$-convergence, we derive a two-dimensional local reduced model. Investigation of this model provides an insight into the formation ...

#### Neoadjuvant chemotherapy versus primary debulking surgery in advanced epithelial ovarian cancer: A meta-analysis of peri-operative outcome

Objective To assess whether neoadjuvant chemotherapy (NACT) is superior to primary debulking surgery (PDS) with regard to optimal cytoreduction, peri-operative morbidity, mortality, and quality of life (QOL) in advanced epithelial ovarian cancer (EOC). Methods We searched the PubMed, Embase, Cochrane Central Register of Controlled Trials, Web of Science, Registers of Clinical ...

#### Breast cancer metastases to the thyroid gland – an uncommon sentinel for diffuse metastatic disease: a case report and review of the literature

Metastases to the thyroid are rare. The most common primary cancer to metastasize to the thyroid is renal cell carcinoma, followed by malignancies of the gastrointestinal tract, lungs, and skin, with breast cancer metastases to the thyroid being rare. Overall, the outcomes in malignancies that have metastasized to the thyroid are poor. There are no prospective studies addressing ...

#### Effect of glycemic control and type of diabetes treatment on unsuccessful TB treatment outcomes among people with TB-Diabetes: A systematic review

Background Stringent glycemic control by using insulin as a replacement or in addition to oral hypoglycemic agents (OHAs) has been recommended for people with tuberculosis and diabetes mellitus (TB-DM). This systematic review (PROSPERO 2016:CRD42016039101) analyses whether this improves TB treatment outcomes. Objectives Among people with drug-susceptible TB and DM on anti-TB ...

#### Hereditary gynaecologic cancers in Nepal: a proposed model of care to serve high risk populations in developing countries

Endometrial, ovarian and breast cancers are paradigms for global health disparity. Women living in the developing world continue to present in later stages of disease and have fewer options for treatment than those in developed countries. Risk reducing surgery is of proven benefit for women at high risk of gynaecological cancer. There is no specific model for identification and ...

#### Generation of an immortalized mesenchymal stem cell line producing a secreted biosensor protein for glucose monitoring

Diabetes is a chronic disease characterized by high levels of blood glucose. Diabetic patients should normalize these levels in order to avoid short and long term clinical complications. Presently, blood glucose monitoring is dependent on frequent finger pricking and enzyme based systems that analyze the drawn blood. Continuous blood glucose monitors are already on market but ...

#### Perspectives on invasive amphibians in Brazil

Introduced species have the potential to become invasive and jeopardize entire ecosystems. The success of species establishing viable populations outside their original extent depends primarily on favorable climatic conditions in the invasive ranges. Species distribution modeling (SDM) can thus be used to estimate potential habitat suitability for populations of invasive species. ...

#### Mating-induced sexual inhibition in the jumping spider Servaea incana (Araneae: Salticidae): A fast-acting and long-lasting effect

Mating-induced sexual inhibition has been studied extensively as an important facet of many insect mating systems but remains little understood in spiders. Once mated, females of many spider species become unreceptive and aggressive toward males, but the speed of onset and persistence of this effect are not known. Addressing this gap, the present study considers (1) mating tendency ...

#### Computed tomography in children with community-acquired pneumonia

Diagnostic imaging plays a significant role in both the diagnosis and treatment of complications of pneumonia in children and chest radiography is the imaging modality of choice. Computed tomography (CT) on the other hand, is not currently a first-line imaging tool for children with suspected uncomplicated community-acquired pneumonia and is largely reserved for when complications ...

#### Stage IV gastric cancer successfully treated by multidisciplinary therapy including chemotherapy, immunotherapy, and surgery: a case report

Background The prognosis of stage IV gastric cancer (GC) still remains unfavorable. Multidisciplinary approaches should therefore be considered to improve the survival of patients with stage IV GC. We report here a case of primary GC with potentially unresectable metastasis, successfully treated by a multidisciplinary approach including chemotherapy, immunotherapy, and surgery. ...

#### Photosystem I-LHCII megacomplexes respond to high light and aging in plants

Photosystem II is known to be a highly dynamic multi-protein complex that participates in a variety of regulatory and repair processes. In contrast, photosystem I (PSI) has, until quite recently, been thought of as relatively static. We report the discovery of plant PSI-LHCII megacomplexes containing multiple LHCII trimers per PSI reaction center. These PSI-LHCII megacomplexes ...

#### A fast source-oriented image clustering method for digital forensics

We present in this paper an algorithm that is capable of clustering images taken by an unknown number of unknown digital cameras into groups, such that each contains only images taken by the same source camera. It first extracts a sensor pattern noise (SPN) from each image, which serves as the fingerprint of the camera that has taken the image. The image clustering is performed ...

#### A battery-less and wireless wearable sensor system for identifying bed and chair exits in a pilot trial in hospitalized older people

Falls in hospitals are common, therefore strategies to minimize the impact of these events in older patients and needs to be examined. In this pilot study, we investigate a movement monitoring sensor system for identifying bed and chair exits using a wireless wearable sensor worn by hospitalized older patients. We developed a movement monitoring sensor system that recognizes bed ...

#### Existence of stable wormholes on a non-commutative-geometric background in modified gravity

In this paper, we discuss spherically symmetric wormhole solutions in f(R, T) modified theory of gravity by introducing well-known non-commutative geometry in terms of Gaussian and Lorentzian distributions of string theory. For analytic discussion, we consider an interesting model of f(R, T) gravity defined by $f(R,T)=f_{1}(R)+\lambda T$. By taking two different choices for the ...

#### Photocatalytic Activities Enhanced by Au-Plasmonic Nanoparticles on TiO2 Nanotube Photoelectrode Coated with MoO3

Although TiO2 was formerly a common material for photocatalysis reactions, its wide band gap (3.2 eV) results in absorbing only ultraviolet light, which accounts for merely 4% of total sunlight. Modifying TiO2 has become a focus of photocatalysis reaction research, and combining two metal oxide semiconductors is the most common method in the photocatalytic enhancement process. When ...

#### Communication-efficient randomized consensus

We consider the problem of consensus in the challenging classic model. In this model, the adversary is adaptive; it can choose which processors crash at any point during the course of the algorithm. Further, communication is via asynchronous message passing: there is no known upper bound on the time to send a message from one processor to another, and all messages and coin flips ...

#### Dermatologist and Patient Preferences in Choosing Treatments for Moderate to Severe Psoriasis

Introduction The objective of the study was to determine the relative importance (RI) of treatment attributes psoriasis patients and physicians consider when choosing between biologic therapies based on psoriasis severity. Methods A discrete choice experiment (DCE) weighting preference for eight sets of hypothetical treatments for moderate or severe psoriasis was conducted. DCE ...

#### Broad recruitment of mGBP family members to Chlamydia trachomatis inclusions

Chlamydia, the most common sexually transmitted pathogen, is an exquisitely adapted Gram-negative obligate intracellular bacterium. Intracellular Chlamydia trachomatis replicate in a specialized vacuole, termed inclusion, which shields the bacterium from antimicrobial immunity of the host cells and acts as a signalling interface. Previously it was shown that members of the ...