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Bayesian Hypothesis Testing of Two Normal Samples using Bootstrap Prior Technique

The most important ingredient in Bayesian analysis is prior or prior distribution. A new prior determination method was developed under the framework of parametric empirical Bayes using bootstrap technique. By way of example, Bayesian estimations of the parameters of a normal distribution with unknown mean and unknown variance conditions were considered, as well as its application ...

On (mn, n, mn, m) relative difference sets with \(\text {gcd}(m,n)=1\)

There has been much research on \((p^{a},p^{b},p^{a},p^{a-b})\) relative difference sets with p a prime, while there are only a few results on (mn, n, mn, m) relative difference sets with \(\text {gcd}(m,n)=1\). The non-existence results on (mn, n, mn, m) relative difference sets with \(\text {gcd}(m,n)=1\) have only been obtained for the following five cases: (1) \(m=p,\ n=q,\ ...

Herausforderungen durch pluviale Überflutungen – Grundlagen, Schäden und Lösungsansätze

Die Anzahl der Berichte über Hochwasserereignisse fernab von Gewässern und daraus resultierende Schäden, ausgelöst von Niederschlagsereignissen und den daraus entstehenden Abflussprozessen, steigt in Österreich in den letzten Jahren an. Vor allem in der Steiermark werden zurzeit einige Untersuchungen bzw. Projekte durchgeführt, die sich dem Thema der pluvialen Überflutungen über ...

The Role of Social Physique Anxiety, Social Support, and Perceived Benefits and Barriers To Exercise in an All-Female Fitness Camp Intervention

International Journal of Exercise Science 10(8): 1094-1104, 2017. Only 20.3% of American adults meet the Center for Disease Control’s minimum recommended volume of exercise for anaerobic and aerobic physical activities (11). This small proportion representing those who reach the suggested physical activity levels is an issue of concern for researchers and practitioners in ...

Amiloride-enhanced gene transfection of octa-arginine functionalized calcium phosphate nanoparticles

Nanoparticles represent promising gene delivery systems in biomedicine to facilitate prolonged gene expression with low toxicity compared to viral vectors. Specifically, nanoparticles of calcium phosphate (nCaP), the main inorganic component of human bone, exhibit high biocompatibility and good biodegradability and have been reported to have high affinity for protein or DNA, having ...

CSLabel: An Approach for Labelling Mobile App Reviews

Mobile apps (applications) have become a popular form of software, and the app reviews by users have become an important feedback resource. Users may raise some issues in their reviews when they use apps, such as a functional bug, a network lag, or a request for a feature. Understanding these issues can help developers to focus on users’ concerns, and help users to evaluate similar ...

A New Framework of Design and Continuous Evaluation to Improve Brain Training

Effective teaching critically relies upon effective evaluation because evaluation is required to gain understanding of existing abilities and, in turn, determine learning outcomes. Methods of effective evaluation are surprisingly elusive in many fields, and this limits our understanding of which training methods are truly effective. In the present article, issues of effective ...

Mechanical dyssynchrony alters left ventricular flow energetics in failing hearts with LBBB: a 4D flow CMR pilot study

The impact of left bundle branch block (LBBB) related mechanical dyssynchrony on left ventricular (LV) diastolic function remains unclear. 4D flow cardiovascular magnetic resonance (CMR) has provided reliable markers of LV dysfunction: reduced volume and kinetic energy (KE) of the portion of LV inflow which passes directly to outflow (Direct Flow) has been demonstrated in failing ...

Reflexion Sur Les Enjeux Epistemologique Et Methodologique De L’approche Anthropologique Sur La Maladie Chronique En Contexte Africain A Travers L’exemple Du VIH/Sida

Our practical experience of anthropology in the field of HIV/AIDS and many researchers’ commitment in such scientific programs showed that social sciences’ approach of chronic disease in African cultural context includes relevant epistemological and methodological issues. The purpose of this article is to give an overview of these issues while showing the contribution of the ...

Multipath Curved Planar Reformations of Peripheral CT Angiography: Diagnostic Accuracy and Time Efficiency

Objectives To compare diagnostic performance and time efficiency between 3D multipath curved planar reformations (mpCPRs) and axial images of CT angiography for the pre-interventional assessment of peripheral arterial disease (PAD), with digital subtraction angiography as the standard of reference. Methods Forty patients (10 females, mean age 72 years), referred to CTA prior to ...

Video-based heart rate monitoring across a range of skin pigmentations during an acute hypoxic challenge

The robust monitoring of heart rate from the video-photoplethysmogram (video-PPG) during challenging conditions requires new analysis techniques. The work reported here extends current research in this area by applying a motion tolerant algorithm to extract high quality video-PPGs from a cohort of subjects undergoing marked heart rate changes during a hypoxic challenge, and ...

Aboriginal Community Engagement in Primary Schooling: Promoting Learning through a Cross-Cultural Lens

This article reports on action research conducted at a primary school in rural New South Wales, Australia. The research responded to an expressed school aspiration to foster greater understanding of local Aboriginal culture, historical perspectives and knowledge systems within the school. An exploratory model was developed using a mixed methods approach to investigate ...

Correction to: A Two-Layer Computational Model for Discrimination of Enhancer and Their Types Using Hybrid Features Space of Pseudo K-Tuple Nucleotide Composition

The original version of this article unfortunately contained a mistake. One character was missing in the title, which was therefore incorrectly given as “A Two-Layer Computational Model for Discrimination of Enhancer and Their Types Using Hybrid Features Pace of Pseudo K-Tuple Nucleotide Composition”.

Budget Impact Analysis of PCSK9 Inhibitors for the Management of Adult Patients with Heterozygous Familial Hypercholesterolemia or Clinical Atherosclerotic Cardiovascular Disease

Objective The aim of this study was to assess the budget impact of introducing the proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) alirocumab and evolocumab to market for the treatment of adults with heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular (CV) disease requiring additional lowering of low-density lipoprotein ...

Zebrafish skeleton development: High resolution micro-CT and FIB-SEM block surface serial imaging for phenotype identification

Although bone is one of the most studied living materials, many questions about the manner in which bones form remain unresolved, including fine details of the skeletal structure during development. In this study, we monitored skeleton development of zebrafish larvae, using calcein fluorescence, high-resolution micro-CT 3D images and FIB-SEM in the block surface serial imaging ...

The role of the clinical departments for understanding patient heterogeneity in one-year mortality after a diagnosis of heart failure: A multilevel analysis of individual heterogeneity for profiling provider outcomes

Purpose To evaluate the general contextual effect (GCE) of the hospital department on one-year mortality in Swedish and Danish patients with heart failure (HF) by applying a multilevel analysis of individual heterogeneity. Methods Using the Swedish patient register, we obtained data on 36,943 patients who were 45–80 years old and admitted for HF to the hospital between 2007 and ...

The extracellular matrix protein Edil3 stimulates osteoblast differentiation through the integrin α5β1/ERK/Runx2 pathway

Epidermal growth factor-like repeats and discoidin I-like domain 3 (Edil3) is an extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif that binds integrin. Recently, Edil3 has been implicated in various biological processes, including angiogenesis and cellular differentiation. It can inhibit inflammatory bone destruction. The objective of this study was to explore the ...

Protective effect of Malva sylvestris L. extract in ischemia-reperfusion induced acute kidney and remote liver injury

Mallow (Malva sylvestris L.) has had medicinal and therapeutic uses in addition to its oral consumption. The present study was conducted to examine the protective effect of Malva sylvestris L. extract on ischemia-reperfusion-induced kidney injury and remote organ injuries in the liver. Before ischemia-reperfusion, rats in the different groups received intraperitoneal normal saline ...

Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains

Most humans have pre-existing immunity to influenza viruses. In this study, volunteers (ages of 18–85 years) were vaccinated with split, inactivated Fluzone™ influenza vaccine in four consecutive influenza seasons from 2013 to 2016 seasons. The impact of repeated vaccination on breadth and durability of antibodies was assessed as a result of vaccine strain changes. Total IgG ...

Half of rifampicin-resistant Mycobacterium tuberculosis complex isolated from tuberculosis patients in Sub-Saharan Africa have concomitant resistance to pyrazinamide

Background Besides inclusion in 1st line regimens against tuberculosis (TB), pyrazinamide (PZA) is used in 2nd line anti-TB regimens, including in the short regimen for multidrug-resistant TB (MDR-TB) patients. Guidelines and expert opinions are contradictory about inclusion of PZA in case of resistance. Moreover, drug susceptibility testing (DST) for PZA is not often applied in ...

Variability in the protein profiles in spermatozoa of two sturgeon species

Conventional sperm analysis (i.e., motility and fertility) has been used to evaluate sperm quality. Understanding the quality of sperm on the molecular level in the sturgeons, Acipenser baerii and A. schrenckii, is essential for the improvement of the conservation of genetic resources and farming performance. In this study, we used the iTRAQ proteomics approach to perform proteomic ...