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Osteoporosis in Frail Patients: A Consensus Paper of the Belgian Bone Club

In this consensus paper, the Belgian Bone Club aims to provide a state of the art on the epidemiology, diagnosis, and management of osteoporosis in frail individuals, including patients with anorexia nervosa, patients on dialysis, cancer patients, persons with sarcopenia, and the oldest old. All these conditions may indeed induce bone loss that is superimposed on physiological bone ...

Anti-Mullerian hormone concentrations in individual follicular fluids within one stimulated IVF cycle resemble blood serum values

Purpose Anti-Mullerian hormone (AMH) is commonly known as the most potent marker for ovarian reserve due to its decline as female age increases. While serum AMH (sAMH) levels have been intensively investigated, there is less data regarding AMH concentrations in follicular fluid (FF), since FF has usually been designated as waste product during oocyte collection in assisted ...

HSV-1 interaction to 3-O-sulfated heparan sulfate in mouse-derived DRG explant and profiles of inflammatory markers during virus infection

The molecular mechanism of herpes simplex virus (HSV) entry and the associated inflammatory response in the nervous system remain poorly understood. Using mouse-derived ex vivo dorsal root ganglia (DRG) explant model and single cell neurons (SCNs), in this study, we provided a visual evidence for the expression of heparan sulfate (HS) and 3-O-sulfated heparan sulfate (3-OS HS) ...

Tranen

Ben komt bij De Praktijk omdat hij vaak moet huilen. Hij kan slecht tegen harde stemmen en kan zich moeilijk verweren. Vooral op school komen de tranen snel. Zelf begint hij er steeds meer last van te krijgen. Hij wordt over twee maanden elf jaar en wil helemaal niet zo snel huilen. Ben vindt het lastig om met woorden te vertellen wat hij denkt en voelt. Hij weet wel dat de schelle ...

Design, simulation and analysis of a digital RF MEMS varactor using thick SU-8 polymer

This paper presents the design, simulation and analysis of a 5-bit RF MEMS digital variable capacitor using thick SU-8 polymer to achieve both high capacitance ratio (\(\varvec{C}_{\varvec{r}}\)) and Q-factor. The proposed varactor design consists of five capacitive shunt switches loaded over a co-planar waveguide (CPW) line. This results 32 capacitance steps ranging from 102.23 fF ...

The universe of ANA testing: a case for point-of-care ANA testing

Testing for total antinuclear antibodies (ANA) is a critical tool for diagnosis and management of autoimmune diseases at both the primary care and subspecialty settings. Repurposing of ANA from a test for lupus to a test for any autoimmune condition has driven the increase in ANA requests. Changes in ANA referral patterns include early or subclinical autoimmune disease detection in ...

Evaluation of organic amendment on the effect of cadmium bioavailability in contaminated soils using the DGT technique and traditional methods

Organic amendments have been widely proposed as a remediation technology for metal-contaminated soils, but there exist controversial results on their effectiveness. In this study, the effect of pig manure addition on cadmium (Cd) bioavailability in Cd-contaminated soils was systematically evaluated by one dynamic, in situ technique of diffusive gradients in thin films (DGT) and ...

Are marginals different? Evidence from British elections 1950–2015

We analyse the results of British general elections from 1950 to 2015. In our model, voting is both instrumental and expressive, and is driven both by ideology and the perceived valence of different parties. On most assumptions the model predicts that the safer the seat the lower the swing. The exception is where ideological factors are relatively dominant in instrumental voting, ...

Optimal nitrogen fertilization of boreal conifer forest

Background Forest fertilization offers a means to increase the production of renewable resources. Nitrogen is the most common fertilizer in boreal upland forests. There is plenty of research on the effect of nitrogen fertilization on volume growth, but less research on the optimal timing of fertilization and optimal management of fertilized stands. Methods This study used ...

Efficiency in education

Education is important at national, local and individual levels. Its benefits accrue both to society and to individuals, and as such provision of education in many countries is paid for at least in part from the public purse. With competing demands for government funding, it is important for education to be provided as efficiently as possible. Efficiency occurs when outputs from ...

The association of catastrophizing with quality-of-life outcomes in patients with irritable bowel syndrome

Background Catastrophizing is a cognitive process characterized by a propensity to concentrate on and magnify the value of an actual or anticipated painful stimulus and negatively assesses one’s ability to cope. Catastrophizing is an important predictor of pain-related outcomes. A cornerstone symptom of irritable bowel syndrome (IBS) is abdominal pain or discomfort. Also ...

Anxiety and depression symptoms and migraine: a symptom-based approach research

Background Anxiety and mood disorders have been shown to be the most relevant psychiatric comorbidities associated with migraine, influencing its clinical course, treatment response, and clinical outcomes. Limited information is available on how specific anxiety and depression symptoms are related to migraine. Symptoms-based approach, a current trend in mental health research, may ...

Monolayer MoS2 decorated Cu7S4-Au nanocatalysts for sensitive and selective detection of mercury(II)

Sensitive and selective detection of Hg(II) contamination is of great importance with concern of public health. Herein, we successfully fabricated monolayer MoS2 (S-MoS2) decorated Cu7S4-Au (Cu7S4-Au@S-MoS2) nanocomposite modified electrode for the sensitive and selective detection of Hg(II) via anodic stripping voltammetric technique. Due to the excellent electrocatalytic ...

How to bail out your local club: the application of the State aid rules to professional football clubs in financial difficulty

This article analyzes the decisions involving State aid granted to professional football clubs in financial difficulty, namely Willem II, MVV Maastricht, NEC Nijmegen, FC Den Bosch and Valencia CF. The decisions are fundamentally different in one very important aspect: the aid granted to the Dutch clubs was declared compatible aid, whereas the aid granted to Valencia CF was ...

Amnestic MCI Patients’ Perspectives toward Disclosure of Amyloid PET Results in a Research Context

Background Researchers currently are not obligated to share individual research results (IRR) with participants. This non-disclosure policy has been challenged on the basis of participants’ rights to be aware and in control of their personal medical information. Here, we determined how patients view disclosure of research PET results of brain amyloid and why they believe it is ...

Classical biological control of insect pests of trees: facts and figures

Classical biological control (CBC) is the introduction of a natural enemy of exotic origin to control a pest, usually also exotic, aiming at permanent control of the pest. CBC has been carried out widely over a variety of target organisms, but most commonly against insects, using parasitoids and predators and, occasionally, pathogens. Until 2010, 6158 introductions of parasitoids ...

Formation of Zirconium Hydrophosphate Nanoparticles and Their Effect on Sorption of Uranyl Cations

Organic-inorganic ion-exchangers were obtained by incorporation of zirconium hydrophosphate into gel-like strongly acidic polymer matrix by means of precipitation from the solution of zirconium oxychloride with phosphoric acid. The approach for purposeful control of a size of the incorporated particles has been developed based on Ostwald-Freundich equation. This equation has been ...