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The gravitational sector of 2d (0, 2) F-theory vacua

F-theory compactifications on Calabi-Yau fivefolds give rise to two-dimensional N = (0, 2) supersymmetric field theories coupled to gravity. We explore the dilaton supergravity defined by the moduli sector of such compactifications. The massless moduli spectrum is found by uplifting Type IIB compactifications on Calabi-Yau fourfolds. This spectrum matches expectations from duality ...

Cardiovascular disease biomarkers are associated with declining renal function in type 2 diabetes

Aims/hypothesis We investigated whether biochemical cardiovascular risk factors and/or markers of subclinical cardiovascular disease were associated with the development of reduced renal function in people with type 2 diabetes. Methods A cohort of 1066 Scottish men and women aged 60–74 years with type 2 diabetes from the Edinburgh Type 2 Diabetes Study were followed up for a median ...

Nonperturbative QED vacuum birefringence

In this paper we represent nonperturbative calculation for one-loop Quantum Electrodynamics (QED) vacuum birefringence in presence of strong magnetic field. The dispersion relations for electromagnetic wave propagating in strong magnetic field point to retention of vacuum birefringence even in case when the field strength greatly exceeds Sauter-Schwinger limit. This gives a ...

Improved determination of the Higgs mass in the MSSM with heavy superpartners

We present several advances in the effective field theory calculation of the Higgs mass in MSSM scenarios with heavy superparticles. In particular, we compute the dominant two-loop threshold corrections to the quartic Higgs coupling for generic values of the relevant SUSY-breaking parameters, including all contributions controlled by the strong gauge coupling and by the ...

O(N) invariance of the multi-field bounce

In his 1977 paper on vacuum decay in field theory: The Fate of the False Vacuum, Coleman considered the problem of a single scalar field and assumed that the minimum action tunnelling field configuration, the bounce, is invariant under O(4) rotations in Euclidean space. A proof of the O(4) invariance of the bounce was provided later by Coleman, Glaser, and Martin (CGM), who ...

Supersymmetry in open superstring field theory

We realize the 16 unbroken supersymmetries on a BPS D-brane as invariances of the action of the corresponding open superstring field theory. We work in the small Hilbert space approach, where a symmetry of the action translates into a symmetry of the associated cyclic A ∞ structure. We compute the supersymmetry algebra, being careful to disentangle the components which produce a ...

Study on the radiative decays of \(h_c\) via intermediate meson loops model

Recently, the BESIII Collaboration reported two new decay processes: \(h_c(1P)\rightarrow \gamma \eta \) and \(\gamma \eta ^\prime \). Inspired by this measurement, we propose to study the radiative decays of \(h_c\) via intermediate charmed meson loops in an effective Lagrangian approach. With the acceptable cutoff parameter range, the calculated branching ratios of ...

Neutrino lines from majoron dark matter

Models with spontaneously broken global lepton number can lead to a pseudo-Goldstone boson as a long-lived dark matter candidate. Here we revisit the case of singlet majoron dark matter and discuss multiple constraints. For masses above MeV, this model could lead to a detectable flux of monochromatic mass-eigenstate neutrinos, which have flavor ratios that depend strongly on the ...

Antibodies to post-translationally modified insulin as a novel biomarker for prediction of type 1 diabetes in children

Aims/hypothesis We have shown that autoimmunity to insulin in type 1 diabetes may result from neoepitopes induced by oxidative post-translational modifications (oxPTM). Antibodies specific to oxPTM-insulin (oxPTM-INS-Ab) are present in most newly diagnosed individuals with type 1 diabetes and are more common than autoantibodies to native insulin. In this study, we investigated ...

Brine shrimp grazing and fecal production increase sedimentation to the deep brine layer (monimolimnion) of Great Salt Lake, Utah

Great Salt Lake (Utah) has a monimolimnion with high concentrations of salts, particulate matter, nutrients, and mercury. To test the importance of brine shrimp (Artemia franciscana) grazing on particulate matter flux, we created salinity gradients in 160-cm high columns, reflecting the lake’s gradient. Two experiments were performed in replicated columns with or without Artemia. ...

(2, 2) superconformal bootstrap in two dimensions

We find a simple relation between two-dimensional BPS \( \mathcal{N}=2 \) superconformal blocks and bosonic Virasoro conformal blocks, which allows us to analyze the crossing equations for BPS 4-point functions in unitary (2, 2) superconformal theories numerically with semidefinite programming. We constrain gaps in the non-BPS spectrum through the operator product expansion of BPS ...

Reconstruction of primary vertices at the ATLAS experiment in Run 1 proton–proton collisions at the LHC

This paper presents the method and performance of primary vertex reconstruction in proton–proton collision data recorded by the ATLAS experiment during Run 1 of the LHC. The studies presented focus on data taken during 2012 at a centre-of-mass energy of \(\sqrt{s} = 8\) TeV. The performance has been measured as a function of the number of interactions per bunch crossing over a wide ...

Spatially modulated instabilities of holographic gauge-gravitational anomaly

We performed a study of the perturbative instabilities in Einstein-Maxwell-Chern-Simons theory with a gravitational Chern-Simons term, which is dual to a strongly coupled field theory with both chiral and mixed gauge-gravitational anomaly. With an analysis of the fluctuations in the near horizon regime at zero temperature, we found that there might be two possible sources of ...

Black holes and solitons in an extended Proca theory

We study a massive vector tensor theory that acquires mass via a standard Proca term but also via a higher order term containing an explicit coupling to curvature. We find static solutions that are asymptotically flat, adS or Lifshitz black holes. Since the higher order term regularizes the effect of the Proca mass term, generically solutions are asymptotically regular for ...

Charmless \(B_{(s)}\rightarrow VV\) decays in factorization-assisted topological-amplitude approach

Within the factorization-assisted topological-amplitude approach, we studied the 33 charmless \(B_{(s)} \rightarrow VV\) decays, where V stands for a light vector meson. According to the flavor flows, the amplitude of each process can be decomposed into eight different topologies. In contrast to the conventional flavor diagrammatic approach, we further factorize each topological ...

Effects of semaglutide on beta cell function and glycaemic control in participants with type 2 diabetes: a randomised, double-blind, placebo-controlled trial

Aims/hypothesis Semaglutide is a glucagon-like peptide-1 analogue in development for the treatment of type 2 diabetes. Its effects on first- and second-phase insulin secretion and other measures of beta cell function and glycaemic control were assessed. Methods In this single-centre, double-blind, placebo-controlled, parallel-group trial, conducted at the Profil Institut für ...

Electron and muon anomalous magnetic dipole moment in a 3–3–1 model

We calculate, in the context of a 3–3–1 model with heavy charged leptons, constraints on some parameters of the extra particles in the model by imposing that their contributions to both the electron and muon (g − 2) factors are in agreement with experimental data up to 1σ-3σ. In order to obtain realistic results we use some of the possible solutions of the left- and right-unitary ...

Resonant CP violation in rare τ ± decays

In this work, we study the lepton number violating tau decays via intermediate on-shell Majorana neutrinos N j into two scalar mesons and a lepton τ ± → M 1 ± N j → M 1 ± M 2 ± ℓ ∓. We calculate the Branching ratios Br(τ ±) and the CP asymmetry (Γ(τ +) − Γ(τ −))/(Γ(τ +) + Γ(τ −)) for such decays, in a scenario that contains at least two heavy Majorana neutrinos. The results show ...

Spatio-semantic user profiles in location-based social networks

Knowledge of users’ visits to places is one of the keys to understanding their interest in places. User-contributed annotations of place, the types of places they visit, and the activities they carry out, add a layer of important semantics that, if considered, can result in more refined representations of user profiles. In this paper, semantic information is summarised as tags for ...

Seeing through the network: Competitive advantage in the digital economy

Firms operate in an environment that is increasingly permeated with digital technology. The incorporation of digital technology into products, services, and operations has significant implications on how firms can attain and sustain competitive advantage. Traditional strategic models of competitive advantage – such as the industry structure view, the resource-based view or the ...

Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice

Aims/hypothesis Overeating of dietary fats causes obesity in humans and rodents. Recent studies in humans and rodents have demonstrated that addiction to fats shares a common mechanism with addiction to alcohol, nicotine and narcotics in terms of a dysfunction of brain reward systems. It has been highlighted that a high-fat diet (HFD) attenuates dopamine D2 receptor (D2R) ...

Trabeculotomy opening size and IOP reduction after Trabectome® surgery

Background Trabeculotomy with the Trabectome® is an effective surgical procedure to lower intraocular pressure (IOP). However, in some patients it does not lead to a significant IOP reduction despite a gonioscopically well visible opening of Schlemm’s canal. This study investigated whether the size of the trabeculotomy opening and other parameters, including anterior chamber depth ...

Evaluation of Crack Propagation and Post-cracking Hinge-type Behavior in the Flexural Response of Steel Fiber Reinforced Concrete

An experimental evaluation of crack propagation and post-cracking behavior in steel fiber reinforced concrete (SFRC) beams, using full-field displacements obtained from the digital image correlation technique is presented. Surface displacements and strains during the fracture test of notched SFRC beams with volume fractions (Vf) of steel fibers equal to 0.5 and 0.75% are analyzed. ...

Chloroplast Genome Sequence Annotation of <i>Dendrobium nobile</i> (Asparagales: Orchidaceae), an Endangered Medicinal Orchid from Northeast India

Orchidaceae constitutes one of the largest families of angiosperms. Owing to the significance of orchids in plant biology, market needs and current sustainable technology levels, basic research on the biology of orchids and their applications in the orchid industry is increasing. Although chloroplast (cp) genomes continue to be evolutionarily informative, there is very limited ...