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Seed tissue and nutrient partitioning, a case for the nucellus

Flowering plants display a large spectrum of seed architectures. The volume ratio of maternal versus zygotic seed tissues changes considerably among species and underlies different nutrient-storing strategies. Such diversity arose through the evolution of cell elimination programs that regulate the relative growth of one tissue over another to become the major storage compartment...

DGS-PraxisLeitlinie Cannabis auf gutem Weg

Auch ein Jahr nach Inkrafttreten des Cannabisgesetzes herrscht aufgrund limitierter Evidenz noch Unsicherheit, bei welchen Indikationen eine Therapie mit Cannabinoiden sinnvoll und sicher durchgeführt werden kann. Eine Orientierungshilfe bietet jetzt die neue DGS-PraxisLeitlinie „Cannabis in der Schmerztherapie“, die Ärzte bei der Verordnung von Cannabinoiden, aber auch im Umgang...

Association between periprosthetic tissue metal content, whole blood and synovial fluid metal ion levels and histopathological findings in patients with failed metal-on-metal hip replacement

Adverse Reaction to Metal Debris (ARMD) is a major cause of implant failure leading to revision surgery in patients with metal-on-metal (MoM) hip arthroplasties. However, the pathogenesis and its association to implant wear are poorly understood and previous studies have yielded discrepant results. We sought to investigate the associations between histological findings, whole...

Material and Optical Properties of Fluorescent Carbon Quantum Dots Fabricated from Lemon Juice via Hydrothermal Reaction

The water-soluble fluorescent carbon quantum dots (CQDs) are synthesized by utilizing lemon juice as carbon resource via a simple hydrothermal reaction. The obtained CQDs are with an average size of 3.1 nm. They reveal uniform morphology and well-crystalline and can generate bright blue-green light emission under UV or blue light irradiation. We find that the fluorescence from...

Dietary and genetic risk scores and incidence of type 2 diabetes

BackgroundBoth lifestyle and genetic predisposition determine the development of type 2 diabetes (T2D), and studies have indicated interactions between specific dietary components and individual genetic variants. However, it is unclear whether the importance of overall dietary habits, including T2D-related food intakes, differs depending on genetic predisposition to T2D. We...

Microwave-assisted synthesis of silver nanoparticles and their application in catalytic, antibacterial and antioxidant activities

Eco-friendly silver nanoparticles (AgNPs) were synthesized using a carboxymethylated gum kondagogu (CMGK) as capping and reducing agent by microwave irradiation method. Synthesized AgNPs were analyzed by TEM, showed spherical in shape with an average particle size distribution of 9 ± 2 nm. XRD results showed that the cubic-structured AgNPs with crystallite size of 8.6 nm. The...

Food fraud and the perceived integrity of European food imports into China

Background/Aims Persistent incidents of food fraud in China have resulted in low levels of consumer trust in the authenticity and safety of food that is domestically produced. We examined the relationship between the concerns of Chinese consumers regarding food fraud, and the role that demonstrating authenticity may play in relieving those concerns. Methods A two-stage mixed...

Stephani cosmology: entropically viable but observationally challenged

Inhomogeneous cosmological models such as the Stephani universes could, in principle, provide an explanation for the observed accelerated expansion of the Universe. Working with a concrete, popular model of the Stephani cosmology – the Stephani-Da̧browski model, we found that it is entropically viable. We also comment on the energy conditions and the two-sheeted geometry of the...

Outcome of polycystic kidney disease patients on peritoneal dialysis: Systematic review of literature and meta-analysis

Background Polycystic kidney disease (PKD) is the most frequent hereditary cause of chronic kidney disease. Peritoneal dialysis (PD) is often avoided for patients with PKD because of the suspected risk of mechanical and infectious complications. Only a few studies have analyzed the outcome of PKD patients on PD with sometimes conflicting results. The purpose of this meta-analysis...

Optimization of Uncertain Structures with Interval Parameters Considering Objective and Feasibility Robustness

For the purpose of improving the mechanical performance indices of uncertain structures with interval parameters and ensure their robustness when fluctuating under interval parameters, a constrained interval robust optimization model is constructed with both the center and halfwidth of the most important mechanical performance index described as objective functions and the other...

Bacterial versus human thymidylate synthase: Kinetics and functionality

Thymidylate Synthase (TSase) is a highly conserved enzyme that catalyzes the production of the DNA building block thymidylate. Structurally, functionally and mechanistically, bacterial and mammalian TSases share remarkable similarities. Because of this closeness, bacterial enzymes have long been used as model systems for human TSase. Furthermore, while TSase inhibitors have long...

Characteristics of variable speed limit systems

The control algorithm used for deciding on the speed limit in variable speed limit systems is crucial for the performance of the systems. The algorithm is designed to fulfil the purpose of the variable speed limit system, which can be one or several of the following aspects: increasing safety, increasing efficiency and decreasing environmental impacts. Today, many of the control...

Improving temporal accuracy of human metabolic chambers for dynamic metabolic studies

Metabolic chambers are powerful tools for assessing human energy expenditure, providing flexibility and comfort for the subjects in a near free-living environment. However, the flexibility offered by the large living room size creates challenges in the assessment of dynamic human metabolic signals—such as those generated during high-intensity interval training and short-term...

Executive function underlies both perspective selection and calculation in Level-1 visual perspective taking

Previous research has suggested that the calculation of another’s perspective is cognitively efficient, whereas perspective selection (selection of a particular perspective, self or other) is associated with executive function, particularly inhibitory control. However, research has not previously tested how perspective calculation and selection may be associated with another key...

Target Organ Damage and Target Systolic Blood Pressure in Clinical Practice: The Campania Salute Network

Lowering systolic blood pressure (SBP) below the conventional threshold (140 mm Hg) reduces left ventricular (LV) hypertrophy and incident cardiovascular (CV) events. We assessed whether different thresholds of SBP as the average value during follow-up (FU) have different impact on changes in target organ damage (TOD).

Introduction: mapping the multiculturalism-interculturalism debate

Since the 1970s multiculturalist policies that recognize and accommodate ethnocultural diversity have been implemented across western democracies. However, the tide seems to have changed: a ‘backlash against multiculturalism’ has been occurring since the 1990s. While it remains unclear whether this backlash is a matter of rhetoric or if there is indeed a wholesale retreat from...

The First Outbreak of Autochthonous Zika Virus in Sabah, Malaysian Borneo

Background: Zika virus (ZIKV) infection is a public health concern. The first ZIKV outside Africa was detected in mosquito in Malaysia. More than six decades ago, serological surveys indicated the presence of human infection with ZIKV in the Malaysian Borneo state of Sabah. It has also been demonstrated that orangutans in Sabah have antibodies against ZIKV. Several years ago, a...

Performance on the APACHE II, SAPS II, SOFA and the OHCA score of post-cardiac arrest patients treated with therapeutic hypothermia

Objective This study assessed the ability of the Acute Physiologic and Chronic Health Evaluation (APACHE) II score, Simplified Acute Physiology Score (SAPS) II, Sequential Organ Failure Assessment (SOFA) score, and out-of-hospital cardiac arrest (OHCA) score to predict the outcome of OHCA patients who underwent therapeutic hypothermia (TH). Methods This study included OHCA...

Relationship between brain function (aEEG) and brain structure (MRI) and their predictive value for neurodevelopmental outcome of preterm infants

To improve the prediction of neurodevelopmental outcome in very preterm infants, this study used the combination of amplitude-integrated electroencephalography (aEEG) within the first 72 h of life and cranial magnetic resonance imaging (MRI) at term equivalent age. A single-center cohort of 38 infants born before 32 weeks of gestation was subjected to both investigations...