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Antifungal activity of Cardiospermum halicacabum L. (Sapindaceae) against Trichophyton rubrum occurs through molecular interaction with fungal Hsp90

Antifungal activity of Cardiospermum halicacabum L. (Sapindaceae) against Trichophyton rubrum occurs through molecular interaction with fungal Hsp90 Roberta Gaziano,1,* Elena Campione,2,* Federico Iacovelli,3 Daniele Marino,1 Francesca Pica,1 Paolo Di Francesco,1 Stefano Aquaro,4 Francesco Menichini,4 Mattia Falconi,3 Luca Bianchi2 1Microbiology Section, Department of...

Role of Wnt/β-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance

Role of Wnt/beta-catenin signaling in hepatocellular carcinoma, pathogenesis, and clinical significance Ahmed M Khalaf,1 David Fuentes,1 Ali I Morshid,2 Mata R Burke,3 Ahmed O Kaseb,4 Manal Hassan,4 John D Hazle,1 Khaled M Elsayes2 1Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, TX, USA; 2Department of Diagnostic Radiology, University of...

Gender differences in the protective effects of green tea against amnestic mild cognitive impairment in the elderly Han population

Gender differences in the protective effects of green tea against amnestic mild cognitive impairment in the elderly Han population Hua Xu,1,2 Yaping Wang,3 Yefeng Yuan,4 Xulai Zhang,5 Xiaoyun Zuo,6 Lijuan Cui,7 Ying Liu,8 Wei Chen,9 Ning Su,1,2 Haihong Wang,1,2 Feng Yan,1,2 Xia Li,1,2 Tao Wang,1,2 Shifu Xiao1,2 1Department of Geriatric Psychiatry, Shanghai Mental Health Center...

Cannabinoids and agmatine as potential therapeutic alternatives for cisplatin-induced peripheral neuropathy

Cannabinoids and agmatine as potential therapeutic alternatives for cisplatin-induced peripheral neuropathy Basak Donertas,* Cigdem Cengelli Unel,* Kevser Erol Department of Medical Pharmacology, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey *These authors contributed equally to this work Abstract: Cisplatin is a widely used antineoplastic agent in the...

Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2

Overexpression of Beclin1 inhibits proliferation and promotes apoptosis of human laryngeal squamous carcinoma cell Hep-2 Baoluo Wan, Yanzi Zang, Lin Wang Department of Otorhinolaryngology, Henan Province People’s Hospital, Zhengzhou, Henan Province, China Objective: Beclin1 was previously found to be downregulated in human laryngeal cancer (LC) tissues, and it results in poor...

Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers

Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers Teodorikez Wilfox Jimenez-Rodriguez,1–3 Marlene Garcia-Neuer,1 Leila A Alenazy,1,4 Mariana Castells1 1Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; 2Allergy Section, Alicante General University Hospital, Alicante...

Relationship of inferior vena cava collapsibility to ultrafiltration volume achieved in critically ill hemodialysis patients

Relationship of inferior vena cava collapsibility to ultrafiltration volume achieved in critically ill hemodialysis patients Matthew J Kaptein,1,2 John S Kaptein,2 Zayar Oo,2 Elaine M Kaptein2 1Division of Nephrology, Loma Linda University Medical Center, Loma Linda, CA, USA; 2Division of Nephrology, University of Southern California, Los Angeles, CA, USA Background: Ultrasound...

Impact of air pollution on severe acute exacerbation of COPD

Impact of air pollution on severe acute exacerbation of COPD Miqdad Haider,1 Muhammad Nabeel Shafqat,2 Mariam Zafar3 1Department of Internal Medicine, Fatima Memorial Hospital, Fatima Memorial College of Medicine and Dentistry, Lahore, Pakistan; 2Department of Medicine, University of Medical Sciences “Serafin Ruiz de Zarate” Villa Clara (UCMVC), Villa Clara, Cuba; 3Department of...

Kinesiology taping reduces the pain of finger osteoarthritis: a pilot single-blinded two-group parallel randomized trial

Kinesiology taping reduces the pain of finger osteoarthritis: a pilot single-blinded two-group parallel randomized trial Ryckie G Wade,1,2 Claire B Paxman,3 Naomi C Tucker,3 Stephen Southern4 1Department of Plastic and Reconstructive Surgery, Leeds Teaching Hospitals Trust, Leeds, UK; 2Faculty of Medicine and Health Sciences, University of Leeds, Leeds, UK; 3Department of Hand...

Lack of coordination between partners: investigation of Physician-Preferred and Patient-Preferred (4P) basal insulin titration algorithms in the real world

Lack of coordination between partners: investigation of Physician-Preferred and Patient-Preferred (4P) basal insulin titration algorithms in the real world Tong Zhang,1 Yunjuan Zhao,2 Tao Du,2 Xiaodan Zhang,2 Xiaowei Li,2 Ruike Liu,3 Yunlin Wang,4 Bo Chen,5 Ling He,6 Wangen Li2 1Department of Endocrinology, The Third Affiliated Hospital, Southern Medical University, Guangzhou...

Preparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice

Preparation of chitin-amphipathic anion/quaternary ammonium salt ecofriendly dressing and its effect on wound healing in mice Daijun Zhou,1–3 Ruijia Yang,4 Tao Yang,1–3 Malcolm Xing,1–4 Gaoxing Luo1–3 1Institute of Burn Research, 2State Key Laboratory of Trauma, Burn and Combined Injury, 3Key Laboratory of Proteomics of Chongqing, Southwest Hospital, Army Medical University...

IRX-2 natural cytokine biologic for immunotherapy in patients with head and neck cancers

IRX-2 natural cytokine biologic for immunotherapy in patients with head and neck cancers Gregory T Wolf,1 Jeffrey S Moyer,1 Michael J Kaplan,2 Jason G Newman,3 James E Egan,4 Neil L Berinstein,4 Theresa L Whiteside5 1Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, 2Department of Otolaryngology-Head and Neck Surgery, Stanford University...

C-reactive protein may be useful to differentiate idiopathic orbital inflammation and orbital cellulitis in cases with acute eyelid erythema and edema

C-reactive protein may be useful to differentiate idiopathic orbital inflammation and orbital cellulitis in cases with acute eyelid erythema and edema Yuko Nishikawa, Hidehiro Oku, Masahiro Tonari, Junko Matsuo, Jun Sugasawa, Tsunehiko Ikeda Department of Ophthalmology, Osaka Medical College, Takatsuki, Osaka, Japan Purpose: Idiopathic orbital inflammation (IOI) and orbital...

miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case–control study involving 2,740 participants

miRNA-146a rs2910164 C>G polymorphism increased the risk of esophagogastric junction adenocarcinoma: a case-control study involving 2,740 participants Yu Chen,1–3,* Weifeng Tang,4,* Chao Liu,4 Jing Lin,1,2 Yafeng Wang,5 Sheng Zhang,6 Gang Chen,3,7 Xiongwei Zheng3,7 1Department of Medical Oncology, Fujian Cancer Hospital and Fujian Medical University Cancer Hospital, Fuzhou...

Larks, owls, swifts, and woodcocks among fruit flies: differential responses of four heritable chronotypes to long and hot summer days

Larks, owls, swifts, and woodcocks among fruit flies: differential responses of four heritable chronotypes to long and hot summer days Lyudmila P Zakharenko,1,2 Dmitrii V Petrovskii,1 Arcady A Putilov3 1Department of Insect Genetics, Institute of Cytology and Genetics of the Siberian Branch, the Russian Academy of Sciences, Novosibirsk, Russia; 2Faculty of Natural Science...

Bridging the gap between physician and medical student education: using the Train the Trainer model to improve cultural competence training in the clerkship years of medical school

Bridging the gap between physician and medical student education: using the Train the Trainer model to improve cultural competence training in the clerkship years of medical school Paige M Anderson, Allison A Vanderbilt College of Medicine and Life Sciences, University of Toledo, Toledo, OH, USA Abstract: Cultural competence (CC) training has become a required part of medical...

Head-to-head comparison of 1-year aripiprazole long-acting injectable (LAI) versus paliperidone LAI in comorbid psychosis and substance use disorder: impact on clinical status, substance craving, and quality of life

Head-to-head comparison of 1-year aripiprazole long-acting injectable (LAI) versus paliperidone LAI in comorbid psychosis and substance use disorder: impact on clinical status, substance craving, and quality of life Ilaria Cuomo,1,2 Georgios D Kotzalidis,1 Simone de Persis,2 Daria Piacentino,1 Filippo Perrini,2 Emanuela Amici,2 Sergio De Filippis1,2 1Department of Neurosciences...

Exercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review

Exercise assessments and trainings of pulmonary rehabilitation in COPD: a literature review Yuqin Zeng,1–3 Fen Jiang,1–3 Yan Chen,1–3 Ping Chen,1–3 Shan Cai1–3 1Department of Pulmonary and Critical Care Medicine, the Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China; 2Research Unit of Respiratory Disease, Central South University, Changsha, Hunan...

Effect of an educational program on adolescent premenstrual syndrome: lessons from the Great East Japan Earthquake

Effect of an educational program on adolescent premenstrual syndrome: lessons from the Great East Japan Earthquake Takashi Takeda,1,2 Masami Shiina1 1Division of Women’s Health, Research Institute of Traditional Asian Medicine, Kindai University, Osaka, Japan; 2Department of Obstetrics and Gynecology, Tohoku University Graduate School of Medicine, Sendai, Japan Background...

Not enough time for research? Use of supported funding to promote allied health research activity

Not enough time for research? Use of supported funding to promote allied health research activity Rachel Wenke,1,2 Kelly A Weir,1–3 Christy Noble,1,4,5 Jill Mahoney,1 Sharon Mickan1–3 1Allied Health Clinical Governance, Education and Research, Gold Coast Health, QLD, Australia; 2School of Allied Health Sciences, 3Menzies Health Institute Queensland, 4School of Medicine, Griffith...

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma

TRIM44, a crucial target of miR-410, functions as a potential oncogene in osteosarcoma Heng Wang,1,* Zi-Ling Fang,2,* Gong-Hao Zhang,1 Xin Ma1 1Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China; 2Department of Oncology, the First Affiliated Hospital of Nanchang University, Nanchang, People’s Republic of China *These authors...

Heroin-dependent patient satisfaction with methadone as a medication influences satisfaction with basic interventions delivered by staff to implement methadone maintenance treatment

Heroin-dependent patient satisfaction with methadone as a medication influences satisfaction with basic interventions delivered by staff to implement methadone maintenance treatment Saul Alcaraz,1 Carme Viladrich,2 Joan Trujols,1,3 Núria Siñol,1 José Pérez de los Cobos1,3,4 1Addictive Behaviors Unit, Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Biomedical...

Polysaccharide-modified nanoparticles with intelligent CD44 receptor targeting ability for gene delivery

Polysaccharide-modified nanoparticles with intelligent CD44 receptor targeting ability for gene delivery Wen Jen Lin,1,2 Wei Chi Lee1 1School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan; 2Drug Research Center, College of Medicine, National Taiwan University, Taipei, Taiwan Background: Hyaluronic acid (HA) and chondroitin sulfate (CD) are...

Short- versus long-term dual antiplatelet therapy after second-generation drug-eluting stent implantation: a systematic review and meta-analysis of randomized controlled trials

Short- versus long-term dual antiplatelet therapy after second-generation drug-eluting stent implantation: a systematic review and meta-analysis of randomized controlled trials Hongqing Li, Wenqin Guo, Weiran Dai, Lang Li Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Guangxi Cardiovascular Institute, Nanning, Guangxi, China Background: The...