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Bending back stress chains and unique behaviour of granular matter in cylindrical geometries

We analyse the general solutions for the stress field in planar annuli of isostatic media, a model often used for marginally rigid granular materials in Couette cells. We demonstrate that these solutions are much richer than in rectangular symmetries. Even for uniform media, stress chains are found to curve, broaden away from the stress source, attenuate and leak stress into a cone ...

Catestatin, vasostatin, cortisol, and pain assessments in dogs suffering from traumatic bone fractures

Background Traumatic bone fractures cause moderate to severe pain, which needs to be minimized for optimal recovery and animal welfare, illustrating the need for reliable objective pain biomarkers for use in a clinical setting. The objectives of this study were to investigate catestatin (CST) and vasostatin (VS) concentrations as two new potential biomarkers, and cortisol ...

Pijn (en) lijden

Er is een groot verschil tussen pijn en lijden, maar ze zijn nauw met elkaar verbonden. Pijn is goed te behandelen; met lijden ligt het ingewikkelder.

Cosmic acceleration as an optical illusion

We consider light propagation in an inhomogeneous irrotational dust universe with vanishing cosmological constant, with initial conditions as in standard linear perturbation theory. A non-perturbative approach to the dynamics of such a universe is combined with a distance formula based on the Sachs optical equations. Then a numerical study implies a redshift–distance relation that ...

Intestinal-Type Adenocarcinoma: Classification, Immunophenotype, Molecular Features and Differential Diagnosis

Intestinal-type adenocarcinoma is the second most frequent sinonasal adenocarcinoma. High incidence of these tumors is seen among workers with occupational wood dust exposure, particularly of hardwood dusts. Intestinal-type adenocarcinoma has striking histomorphologic and immunophenotypic similarities with colorectal adenocarcinomas, but on the level of molecular pathologic ...

Compared to the amniotic membrane, Wharton’s jelly may be a more suitable source of mesenchymal stem cells for cardiovascular tissue engineering and clinical regeneration

Background The success of developing cardiovascular tissue engineering (CTE) grafts greatly needs a readily available cell substitute for endothelial and interstitial cells. Perinatal annexes have been proposed as a valuable source of mesenchymal stem cells (MSCs) for tissue engineering and regenerative medicine. The objective of the present study is to evaluate the potential of ...

Acute hyperventilation increases the central venous-to-arterial PCO2 difference in stable septic shock patients

Background To evaluate the effects of acute hyperventilation on the central venous-to-arterial carbon dioxide tension difference (∆PCO2) in hemodynamically stable septic shock patients. Methods Eighteen mechanically ventilated septic shock patients were prospectively included in the study. We measured cardiac index (CI), ∆PCO2, oxygen consumption (VO2), central venous oxygen ...

Do Austrian “INTEGRI (integrated care) projects” comply with international definitions and concepts?

One of the biggest challenges for European healthcare systems is the fragmentation of care. To overcome this challenge, integrated care (IC) approaches have been recently implemented. To further improve this method, current and past projects must be monitored and evaluated. However, since the definition of IC is very indistinct and varies significantly in literature, key elements ...

Epidural spinal angiolipoma: a case series

Background Spinal angiolipomas (SAL) are rare benign tumors, commonly presenting with slow progressive spinal cord compression. There are only about 170 cases identified so far. Magnetic resonance imaging (MRI) has become the modality of choice for SAL. The purpose of this article is to report three cases of SAL and their characteristic MRI features. Case presentation Three cases ...

Time-Shared Twin Memristor Crossbar Reducing the Number of Arrays by Half for Pattern Recognition

In this paper, we propose a new time-shared twin memristor crossbar for pattern-recognition applications. By sharing two memristor arrays at different time, the number of memristor arrays can be reduced by half, saving the crossbar area by half, too. To implement the time-shared twin memristor crossbar, we also propose CMOS time-shared subtractor circuit, in this paper. The ...

Construction of low-ethanol–wine yeasts through partial deletion of the Saccharomyces cerevisiae PDC2 gene

We propose an alternative GMO based strategy to obtain Saccharomyces cerevisiae mutant strains with a slight reduction in their ability to produce ethanol, but with a moderate impact on the yeast metabolism. Through homologous recombination, two truncated Pdc2p proteins Pdc2pΔ344 and Pdc2pΔ519 were obtained and transformed into haploid and diploid lab yeast strains. In the pdc2Δ344 ...

Presence and extent of cardiac computed tomography angiography defined coronary artery disease in patients presenting with syncope

Background In syncope patients, presence of coronary artery disease (CAD) is associated with poor prognosis. However, data concerning CAD prevalence in syncope patients without known cardiovascular disease are lacking. Therefore, the aim of this study was to investigate presence and extent of CAD in syncope patients. Methods We included 142 consecutive patients presenting with ...

Optical fiber grating vibration sensor for vibration monitoring of hydraulic pump

In view of the existing electrical vibration monitoring traditional hydraulic pump vibration sensor, the high false alarm rate is susceptible to electromagnetic interference and is not easy to achieve long-term reliable monitoring, based on the design of a beam of the uniform strength structure of the fiber Bragg grating (FBG) vibration sensor. In this paper, based on the analysis ...

Strong factorization property of Macdonald polynomials and higher-order Macdonald’s positivity conjecture

We prove a strong factorization property of interpolation Macdonald polynomials when q tends to 1. As a consequence, we show that Macdonald polynomials have a strong factorization property when q tends to 1, which was posed as an open question in our previous paper with Féray. Furthermore, we introduce multivariate q, t-Kostka numbers and we show that they are polynomials in q, t ...

DNA double-strand breaks in human induced pluripotent stem cell reprogramming and long-term in vitro culturing

Background Human induced pluripotent stem cells (hiPSCs) play roles in both disease modelling and regenerative medicine. It is critical that the genomic integrity of the cells remains intact and that the DNA repair systems are fully functional. In this article, we focused on the detection of DNA double-strand breaks (DSBs) by phosphorylated histone H2AX (known as γH2AX) and ...

Leadership for team learning: the case of university teacher teams

Teacher team involvement is considered a key factor in achieving sustainable innovation in higher education. This requires engaging in team learning behaviors that should result in new knowledge and solutions. However, university teachers are not used to discussing their work practices with one another and tend to neglect any innovation in their tasks. Team leadership behavior is ...

Schizophrenia and substance use comorbidity: a genome-wide perspective

Dual diagnosis with substance use disorders (SUDs) consistently contributes to the premature mortality and increased disability observed in schizophrenia. Large genome-wide association studies are providing the information needed to investigate the genetic architecture of psychiatric disorders. Here, we discuss recent genetic investigations of dual diagnosis (i.e., schizophrenia ...

Cystoid macular edema associated with preservative-free latanoprost after uncomplicated cataract surgery: case report and review of the literature

Background Cystoid macular edema associated with latanoprost administration has been reported in patients after complicated cataract surgery with coexisting risk factors. We present the first case of preservative free latanoprost associated cystoid macular edema that occurred many months after uncomplicated cataract surgery. Case presentation A 65-year old Caucasian female ...

Fatty acid composition of sprat (Sprattus sprattus) and herring (Clupea harengus) in the Baltic Sea as potential prey for salmon (Salmo salar)

Sprat (Sprattus sprattus) and small herring (Clupea harengus) are the dominant prey fish of Atlantic salmon (Salmo salar) in the Baltic Sea. If the fatty acid (FA) proportions of sprat and herring differ, the dietary history of ascending salmon could be determined from their FA profiles. Therefore, we investigated the FA composition of several age groups of whole sprat and small ...