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Search: authors:"Tao Jiang"

227 papers found.
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Effects of Colcemid Concentration on Chromosome Aberration Analysis in Human Lymphocytes

As a part of technical improvements of chromosome aberration analysis on human peripheral lymphocytes for biological radiation dosimetry, we examined the optimal conditions for the use of colcemid in chromosome preparation in order to obtain enough number of cells at metaphase in the first cell division. When treated with colcemid at concentrations below 0.01μg/ml from the...

Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia

Purpose This study compared the effects of nifedipine and metoprolol on collateral-dependent myocardial blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia. Methods Collateral coronary circulation was induced in 15 three-week-old piglets by banding of the proximal left anterior descending coronary artery (LAD). After 8–10...

IMMUNOTHERAPY/BIOLOGICAL THERAPIES

BACKGROUND: Patients with high grade gliomas (HGGs) routinely receive radiation (RT), temozolomide (TMZ), and glucocorticoids and 40% develop severe lymphopenia (lymphocyte counts <500 cells/mm3) 2-months after initiation of concurrent RT/TMZ (Grossman, 2011). The lymphopenia resulting from these three lymphotoxic therapies is associated with shorter survival from tumor...

Surveillance for Polio Eradication in the People's Republic of China

A case-based virus surveillance system for wild poliovirus in China was developed. By 1993, all 30 provincial immunization units and, by 1994, all 29 provincial laboratories were sending computerized data to the national level. In 1993, a county-level, computerized map was operationalized that permitted visual monitoring of the progress of the polio eradication program every...

Dose-effect Relationship of Dicentric and Ring Chromosomes in Lymphocytes of Individuals Living in the High Background Radiation Areas in China

Chromosomes of 39 healthy family members (3 generations from 13 families) living both in the high-level background radiation areas (HBRA) and the control areas (CA) were studied. Cumulative dose from birth to the time of blood sampling was estimated by calculating measured exposure rate in each individual. The cumulative doses ranged 30.9–358.9 and 6.0–59.2 mGy for HBRA and CA...

NEUROSURGICAL TREATMENTS

Patients with cancer are at high risk of developing venous thromboembolism (VTE). The purpose of this study was to review VTE development in patients undergoing craniotomy for a neoplasm, and to further analyze risk based on multiple pre-, intra-, and post-operative variables. We analyzed all consecutive patients at our institution during the years 1999-2010 who were admitted for...

-OMICS AND PROGNOSTIC MARKERS

BACKGROUND: Glioblastomas, the most common primary brain tumors in adults, still continue to have a predominantly fatal outcome. We previously cloned NPAS3 (neuronal PAS 3), a gene which is among the largest genes in the human genome and encodes a transcription factor. We recently discovered NPAS3 drives the progression of malignant astrocytomas as a tumor suppressor, by...