A number of upper rim-functionalized calix[4]thiourea cyclohexanediamine derivatives have been designed, synthesized and used as catalysts for enantioselective Michael addition reactions between nitroolefins and acetylacetone. The optimal catalyst 2 with a mono-thiourea group exhibited good performance in the presence of water/toluene (v/v = 1:2). Under the optimal reaction...
Motivation: Next-generation sequencing (NGS) has revolutionized the study of cancer genomes. However, the reads obtained from NGS of tumor samples often consist of a mixture of normal and tumor cells, which themselves can be of multiple clonal types. A prominent problem in the analysis of cancer genome sequencing data is deconvolving the mixture to identify the reads associated...
Ectopic mammary tissue develops due to the incomplete involution of the mammary crest, which is more frequently located in the axilla and more common in women. This tissue undergoes pathophysiological changes similar to those of the normal breast, among which malignancy is found. The primary carcinoma of this tissue is infrequent and its most common manifestation is the palpable...
Ectopic mammary tissue develops due to the incomplete involution of the mammary crest, which is more frequently located in the axilla and more common in women. This tissue undergoes pathophysiological changes similar to those of the normal breast, among which malignancy is found. The primary carcinoma of this tissue is infrequent and its most common manifestation is the palpable...
Hui-Wen Chiu Yong-Lin Lee Chia-Yi Li Ying-Jan Wang Yu-Hsuan Lee Hexavalent chromium (Cr(VI)) is widely used in many industries but can induce contact dermatitis especially in cement industries. Many
Shu-yi Li,1 Xiao-bin Yang,1 Yue-juan Che,3 Janak Lal Pathak,1 and Gang Wu4 1Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Affiliated Stomatology Hospital of Guangzhou Medical
Shu-yi Li,1 Xiao-bin Yang,1 Yue-juan Che,3 Janak Lal Pathak,1 and Gang Wu4 1Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Affiliated Stomatology Hospital of Guangzhou Medical
Shu-yi Li,1 Xiao-bin Yang,1 Yue-juan Che,3 Janak Lal Pathak,1 and Gang Wu4 1Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Affiliated Stomatology Hospital of Guangzhou Medical
The transforming growth factor β (TGFβ) and bone morphogenetic protein (BMP) signaling pathways are both constitutively activated in triple-negative breast cancer (TNBC). We are interested in isolating the naturally-derived small-molecule inhibitor that could simultaneously targeting TGFβ/BMP pathways and further studying its anti-proliferative/−metastatic effects as well as the...
(Yi Li), the National Natural Science Foundation of China No. 31501002 & 31470070 (Yi Li), Shanxi Scholarship Council of China No.2013-072 (Yi Li) and the Natural Science Foundation of Shanxi No ... .2014011030-4 (Yi Li). Dr. Jong-Joo Kim is supported by a grant (715003-07) from the Research Center from Production Management and Technical Development for High Quality Livestock Products through Agriculture
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases, neuropathologically characterized by misfolded protein aggregation, called Lewy bodies and Lewy neurites. PD is a slow-progressive disease with colonic dysfunction appearing in the prodromal stage and lasting throughout the course of the disease. In order to study PD pathology in the colon, we examined...
Affiliated to Shandong University, 324 Jingwuweiqi Road, Jinan, 250021, Shandong, ChinaGuozong Wang, Yi Li & Shui SunCollege of Clinical Medicine, Shandong University, Jinan, 250012, Shandong, ChinaGuozong ... , ChinaGuanqiao Chen AuthorsSearch for Guozong Wang in:PubMed • Google Scholar Search for Yi Li in:PubMed • Google Scholar Search for Tiantong Sun in:PubMed • Google Scholar Search for Congcong Wang in:PubMed
, Jyun-Yi Li & Hung-Jen Liu Department of Medical Research, Tung’s Taichung MetroHarbor Hospital, Taichung, Taiwan Yu-Kang Chang Department of Nursing, Jen-Teh Junior College of Medicine and Management ... University, Taichung, 402, Taiwan Wei-Ru Huang, Jyun-Yi Li & Hung-Jen Liu Rong Hsing Research Center for Translational Medicine, National Chung Hsing University, Taichung, 402, Taiwan Hung-Jen Liu
This study investigated the effects of microRNA-135a (miR-135a) targeting of glycogen synthase kinase 3β (GSK3β) on the epithelial–mesenchymal transition (EMT), migration and invasion of bladder cancer (BC) cells by mediating the Wnt/β-catenin signaling pathway. BC and adjacent normal tissues were collected from 165 BC patients. Western blotting and quantitative real-time PCR...
Gong,1,2 Yi Li,1,2 Zhongyi Yang,2–5 Biyun Wang,1,2 1Department of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai, People’s Republic of China; 2Department of Oncology, Shanghai ... revision of the manuscript. Xichun Hu, Yingjian Zhang, Jian Zhang and Zhonghua Wang provided the data. Chengcheng Gong, Yi Li and Yannan Zhao revised the manuscript. Biyun Wang and Zhongyi Yang designed
Correspondence should be addressed to Yi Li; nc.ude.ulj@eelyrneh Received 15 December 2017; Revised 28 February 2018; Accepted 29 April 2018; Published 24 June 2018 Academic Editor: Donato Sorgente Copyright
Correspondence should be addressed to Yi Li; nc.ude.ulj@eelyrneh Received 15 December 2017; Revised 28 February 2018; Accepted 29 April 2018; Published 24 June 2018 Academic Editor: Donato Sorgente Copyright
Correspondence should be addressed to Yi Li; nc.ude.ulj@eelyrneh Received 15 December 2017; Revised 28 February 2018; Accepted 29 April 2018; Published 24 June 2018 Academic Editor: Donato Sorgente Copyright
