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The Dress of Rectors at the Scottish Universities

The Rector’s gown at the University of St Andrews is arguably the only surviving relic of true medieval academical dress in Scotland. Today, the students of each of the ancient universities at St Andrews, Glasgow, Aberdeen and Edinburgh elect a Rector every three years to preside over Court, the governing body of the institutions. The University of Dundee also elects a Rector but, ...

The RUDY study platform – a novel approach to patient driven research in rare musculoskeletal diseases

Background Research into rare diseases is becoming more common, with recognition of the significant diagnostic and therapeutic care gaps. Registries are considered a key research methodology to address rare diseases. This report describes the structure of the Rare UK Diseases Study (RUDY) platform that aims to improve research processes and address many of the challenges of ...

A novel accelerometer-based method to describe day-to-day exposure to potentially osteogenic vertical impacts in older adults: findings from a multi-cohort study

Summary This observational study assessed vertical impacts experienced in older adults as part of their day-to-day physical activity using accelerometry and questionnaire data. Population-based older adults experienced very limited high-impact activity. The accelerometry method utilised appeared to be valid based on comparisons between different cohorts and with self-reported ...

Life-course approach to nutrition

Alliance ( 2014 ) Fracture Prevention Central . Accessed 8 Jun 2015 Akesson K, Marsh D , Mitchell PJ , McLellan AR , Stenmark J , Pierroz DD , Kyer C , Cooper C , Group IOFFW ( 2013

The Role of the Posterior Temporal and Medial Prefrontal Cortices in Mediating Learning from Romantic Interest and Rejection

Romantic interest or rejection can be powerful incentives not merely for their emotional impact, but for their potential to transform, in a single interaction, what we think we know about another person—or ourselves. Little is known, though, about how the brain computes expectations for, and learns from, real-world romantic signals. In a novel “speed-dating” paradigm, we had ...

A longitudinal cohort study of HIV ‘treatment as prevention’ in gay, bisexual and other men who have sex with men: the Treatment with Antiretrovirals and their Impact on Positive And Negative men (TAIPAN) study protocol

Background Australia has increased coverage of antiretroviral treatment (ART) over the past decade, reaching 73% uptake in 2014. While ART reduces AIDS-related deaths, accumulating evidence suggests that it could also bolster prevention efforts by reducing the risk of HIV transmission (‘treatment as prevention’). While promising, evidence of community-level impact of treatment as ...

Real-world effectiveness of peginterferon α-2b plus ribavirin in a Canadian cohort of treatment-naïve chronic hepatitis C patients with genotypes 2 or 3: results of the PoWer and RediPEN studies

The purpose of this investigation was to assess the real-life effectiveness of pegylated interferon (peg-IFN) α-2b with ribavirin (RBV) in a cohort of treatment-naïve patients with chronic genotypes 2 (G2) or 3 (G3) hepatitis C virus (HCV) infection. A post-hoc pooled analysis of two Canadian multicenter, observational studies, RediPEN and PoWer, was carried out. A total of 1242 ...

Ischaemic cardiac events and use of strontium ranelate in postmenopausal osteoporosis: a nested case–control study in the CPRD

Summary We explored the cardiac safety of the osteoporosis treatment strontium ranelate in the UK Clinical Practice Research Datalink. While known cardiovascular risk factors like obesity and smoking were associated with increased cardiac risk, use of strontium ranelate was not associated with any increase in myocardial infarction or cardiovascular death. Introduction It has been ...

Non-invasive Assessment of Lower Limb Geometry and Strength Using Hip Structural Analysis and Peripheral Quantitative Computed Tomography: A Population-Based Comparison

. J. Denison, K. A. Jameson, M. H. Edwards, A. A. Sayer, P. Taylor, C. Cooper, E. M. Dennison) declare no conflict of interest Human and Animal Rights and Informed Consent Ethical permission for the

The Scarlet Gown: History and Development of Scottish Undergraduate Dress

The scarlet gown is synonymous with student life in Scotland. Although its beginnings are mysterious, the purpose of this article is to shed some light on its origin and to describe its development through the centuries. We shall examine Scottish student dress in pre-Reformation times and briefly survey the early use of red student gowns in Europe. The history of the scarlet gown ...

Impact of hip fracture on hospital care costs: a population-based study

fractures in postmenopausal women . NICE technology appraisal guidance TA161 . 31. Åkesson K , Marsh D , Mitchell PJ , McLellan AR , Stenmark J , Pierroz DD , Kyer C ... , Cooper C ( 2013 ) Capture the fracture: a best practice framework and global campaign to break the fragility fracture cycle . Osteoporos Int 24 : 2135 - 2152 32. Abrahamsen B , van Staa T , Ariely R

Where now with NICE?

E. M. Dennison C. Cooper 0 ) MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital , Southampton SO16 6YD, UK - The National Institute of Clinical Excellence

The unfolded protein response is required for dendrite morphogenesis

Taylor, Roshni C Cooper, Kang Shen Xing Wei, Audrey S Howell, Xintong Dong, Caitlin A Taylor, Roshni C Cooper, Kang Shen The funders had no role in study design, data collection and interpretation, or the ... . the python code for image processing and data analysis. DOI: 10.7554/eLife.06963.025 5R01NS082208-02 Xing Wei, Audrey S Howell, Xintong Dong , Caitlin A Taylor, Roshni C Cooper, Kang Shen Arakawa

Behavioral economics: implications for regulatory behavior

James C. Cooper 0 William E. Kovacic 0 0 J. C. Cooper Law & Economics Center, George Mason University School of Law , Arlington, VA, USA Behavioral economics (BE) examines the implications for

Effect of Roux-en-Y Gastric Bypass Surgery on Bile Acid Metabolism in Normal and Obese Diabetic Rats

In addition to classic functions of facilitating hepatobiliary secretion and intestinal absorption of lipophilic nutrients, bile acids (BA) are also endocrine factors and regulate glucose and lipid metabolism. Recent data indicate that antiobesity bariatric procedures e.g. Roux-en-Y gastric bypass surgery (RYGB), which also remit diabetes, increase plasma BAs in humans, leading to ...

Lack of Modulation of Nicotinic Acetylcholine Alpha-7 Receptor Currents by Kynurenic Acid in Adult Hippocampal Interneurons

Kynurenic acid (KYNA), a classical ionotropic glutamate receptor antagonist is also purported to block the α7-subtype nicotinic acetylcholine receptor (α7* nAChR). Although many published studies cite this potential effect, few have studied it directly. In this study, the α7*-selective agonist, choline, was pressure-applied to interneurons in hippocampal subregions, CA1 stratum ...

Osteoporosis epidemiology in UK Biobank: a unique opportunity for international researchers

GlaxoSmithKline Research and Development , London, UK 1 C. Cooper MRC Lifecourse Epidemiology Unit, University of Southampton , Southampton, UK 2 UK Biobank Musculoskeletal Advisory Group: Chair : Cyrus Cooper (MRC