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Familial Risks of Kidney Failure in Sweden: A Nationwide Family Study

Background The value of family history as a risk factor for kidney failure has not been determined in a nationwide setting. Aim This nationwide family study aimed to determine familial risks for kidney failure in Sweden. Methods The Swedish multi-generation register on 0–78-year-old subjects were linked to the Swedish patient register and the Cause of death register for 1987–2010. ...

Impact of yoga on blood pressure and quality of life in patients with hypertension – a controlled trial in primary care, matched for systolic blood pressure

Swedish Southern Health Care Region, and Agreement for Medical Education and Research (ALF) funding from Region Skåne, and by a Swedish Research Council grant awarded to Kristina Sundquist. 1. Kearney PM

Immigrant enclaves and risk of diabetes: a prospective study

. Acknowledgements This work was supported by the National Institute of Diabetes and Digestive and Kidney Diseases (R21-DK8356430) to Briana Mezuk and the Swedish Research Council to Kristina Sundquist (20113340). The

Incidence of hereditary amyloidosis and autoinflammatory diseases in Sweden: endemic and imported diseases

Background Amyloidoses are a heterogeneous group of progressive diseases caused by tissue deposition of misfolded proteins. According to the International Classification of Diseases, hereditary amyloidosis is divided into neuropathic and non-neuropathic forms. In Sweden, neuropathic heredofamilial amyloidosis has been identified as familial amyloidotic polyneuropathy (FAP), a fatal ...

Availability of exercise facilities and physical activity in 2,037 adults: cross-sectional results from the Swedish neighborhood and physical activity (SNAP) study

Ulf Eriksson 0 Daniel Arvidsson 0 Kristina Sundquist 0 0 Center for Primary Health Care Research, Lund University, Skane University Hospital , CRC, Building 28, Floor 11, Entrance 72, S-205 02 ... grants to Dr Kristina Sundquist from the Swedish Council for Working Life and Social Research (FAS; 2006-0386) and The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning

Digested wheat gluten inhibits binding between leptin and its receptor

Background Leptin resistance is considered a primary risk factor for obesity. It has been hypothesized that dietary cereal grain protein could cause leptin resistance by preventing leptin from binding to its receptor. Non-degraded dietary wheat protein has been found in human serum at a mean level of 41 ng/mL. Here, we report our findings from testing whether enzymatically digested ...

A Population-Based Study of Hepatitis D Virus as Potential Risk Factor for Hepatocellular Carcinoma

Jianguang Ji Jianguang.ji@med 0 Kristina Sundquist 0 Jan Sundquist 0 0 Floor 11, Entrance 72, Skne University Hospital , Malm 205 02, Sweden ( Hepatitis D virus (HDV) is dependent on the presence of

Do Reproductive Factors Influence T, N, and M Classes of Ductal and Lobular Breast Cancers? A Nation-Wide Follow-Up Study

Backgrounds The clinical tumor-node-metastasis (T, N and M) classes of breast cancers provide important prognostic information. However, the possible association of TNM classes with reproductive factors has remained largely unexplored. Because every woman has a reproductive history, implications to outcome prediction are potentially significant. Methods During the study period from ...

Does the risk of stomach cancer remain among second-generation immigrants in Sweden?

The observed increased risks of noncardia stomach cancer among foreign-born second-generation immigrants compared to the Swedes suggest that these immigrants were infected by Helicobacter pylori before immigration.

Neighbourhood Environment and Stroke: A Follow-Up Study in Sweden

Background In recent years, research on the association between physical environments and cardiovascular disease outcomes has gained momentum with growing attention being paid to Geographic Information Systems (GIS). This nationwide study is the first to examine the effect of neighbourhood physical environments on individual-level stroke, using GIS-based measures of neighbourhood ...

Comparison of survival of patients with metastases from known versus unknown primaries: survival in metastatic cancer

Background Cancer of unknown primary site (CUP) is considered an aggressive metastatic disease but whether the prognosis differs from metastatic cancers of known primary site is not known. Such data may give insight into the biology of CUP and the metastatic process in general. Methods 6,745 cancer patients, with primary metastatic cancer at diagnosis, were identified from the ...

Determination of 14 Circulating microRNAs in Swedes and Iraqis with and without Diabetes Mellitus Type 2

Background Recent reports suggest that immigrants from Middle Eastern countries are a high-risk group for type 2 diabetes (T2D) compared with Swedes, and that the pathogenesis of T2D may be ethnicity-specific. Deregulation of microRNA (miRNA) expression has been demonstrated to be associated with T2D but ethnic differences in miRNA have not been investigated. The aim of this study ...

Family history as a risk factor for recurrent hospitalization for lone atrial fibrillation: a nationwide family study in Sweden

Zller from the Swedish Heart-Lung Foundation and Region Skne (REGSKANE-124611), to Dr Kristina Sundquist from the Swedish Research Council (K2009-70X-15428-05-3; K2012-70X-15428-08-3), to Dr Jan Sundquist ... from the Swedish Council for Working Life and Social Research (20071754) and the Swedish Freemasons Foundation as well as ALF funding from Region Skne awarded to Jan Sundquist and Kristina Sundquist

Effects of prescribed antithrombotics and other cardiovascular pharmacotherapies on all-cause mortality in patients with diabetes and atrial fibrillation – a cohort study from Sweden using propensity score analyses

Laplace regression method. All authors read and approved the final manuscript. Acknowledgments This work was supported by grants to Dr Kristina Sundquist from the Swedish Research Council (K2009-70X-15428 ... -05-3; K2012-70X-15428-08-3), to Dr Jan Sundquist from the Swedish Freemasons Foundation as well as ALF funding from Region Skåne awarded to Jan Sundquist and Kristina Sundquist. 1. Wirehn AB

Incidence and survival in non-hereditary amyloidosis in Sweden

Background Amyloidosis is a heterogeneous disease caused by deposition of amyloid fibrils in organs and thereby interfering with physiological functions. Hardly any incidence data are available and most survival data are limited to specialist clinics. Methods Amyloidosis patients were identified from the Swedish Hospital Discharge and Outpatients Registers from years 2001 through ...

Walkability parameters, active transportation and objective physical activity: moderating and mediating effects of motor vehicle ownership in a cross-sectional study

manuscript for important intellectual content and final approval of the manuscript. Acknowledgments This study was supported by grants to Dr Kristina Sundquist from the Swedish Council for Working Life and

Longitudinal age-and cohort trends in body mass index in Sweden – a 24-year follow-up study

Background The aim of this longitudinal study was to analyze whether mean Body Mass Index (BMI), assessed at four occasions, changed within different age groups and birth cohorts over time, i.e., between 1980/81 and 2004/05, after adjustment for possible confounders. Methods A sample of 2728 men and 2770 women aged 16–71 years at study start were randomly drawn from the Swedish ...

Co-Morbidity between Early-Onset Leukemia and Type 1 Diabetes – Suggestive of a Shared Viral Etiology?

Background Acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) are common early-onset malignancies. Their causes are largely unknown but infectious etiology has been implicated. Type 1 diabetes (T1D) is an autoimmune disease for which infectious triggers of disease onset have been sought and increasing pointing to enteroviruses. Based on our previous results on ...

Risk of subsequent ischemic and hemorrhagic stroke in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden

Sundquist 0 Kristina Sundquist 0 0 Center for Primary Health Care Research, Lund University/Region Skane, Clinical Research Centre , Floor 11, Building 28, Entrance 72 , Skane University Hospital , 205 02

A culturally adapted lifestyle intervention addressing a Middle Eastern immigrant population at risk of diabetes, the MEDIM (impact of Migration and Ethnicity on Diabetes In Malmö): study protocol for a randomized controlled trial

Background Studies have shown that lifestyle interventions are effective in preventing or delaying the onset of type 2 diabetes in high-risk patients. However, research on the effectiveness of lifestyle interventions in high-risk immigrant populations with different cultural and socioeconomic backgrounds is scarce. The aim was to design a culturally adapted lifestyle intervention ...