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Stathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cells

Stathmin1 increases radioresistance by enhancing autophagy in non-small-cell lung cancer cells Xi Zhang,1,2 Jingfen Ji,3 Yu Yang,4 Juan Zhang,2 Liangfang Shen1 1Department of Oncology, Xiangya

miR-589-5p inhibits MAP3K8 and suppresses CD90 + cancer stem cells in hepatocellular carcinoma

Background Cancer stem cells (CSCs) are important in the tumorigenesis and progression of hepatocellular carcinoma (HCC). MicroRNAs (miRNAs) play crucial roles regulating CD133 + and EpCAM + CSCs in HCC, although it is unclear whether miRNAs regulate CD90 + CSCs in HCC. Methods The miRNA profiles of CD90 + and CD90 - HCC cells were analyzed using a miRNA microarray and...

Seminal fluid protein genes of the brown planthopper, Nilaparvata lugens

Background Seminal fluid proteins (SFPs) are produced mainly in the accessory gland of male insects and transferred to females during mating, in which they induce numerous physiological and post-mating behavioral changes. The brown plant hopper (BPH), Nilaparvata lugens, is an economically important hemipterous pest of rice. The behavior and physiology of the female of this...

Effect of aerobic exercise training on cardiometabolic risk factors among professional athletes in the heaviest-weight class

Background High prevalence of metabolic diseases among young professional athletes with large body sizes has raised growing attention. However, few studies specifically examined whether additional aerobic exercise provides cardiometabolic beneficial effect among these young athletes under regularly intensive strength training. Objective We conducted a pilot trial to evaluate the...

Disparities between Ophthalmologists and Patients in Estimating Quality of Life Associated with Diabetic Retinopathy

Background This study aimed to evaluate and compare the utility values associated with diabetic retinopathy (DR) in a sample of Chinese patients and ophthalmologists. Methods Utility values were evaluated by both the time trade-off (TTO) and rating scale (RS) methods for 109 eligible patients with DR and 2 experienced ophthalmologists. Patients were stratified by Snellen best...

Perfusion Deficits and Functional Connectivity Alterations in Memory-Related Regions of Patients with Post-Traumatic Stress Disorder

To explore the potential alterations in cerebral blood flow (CBF) and functional connectivity of recent onset post-traumatic stress disorder (PTSD) induced by a single prolonged trauma exposure, we recruited 20 survivors experiencing the same coal mining flood disaster as the PTSD (n = 10) and non-PTSD (n = 10) group, respectively. The pulsed arterial spin labeling (ASL) images...

A Wideband Dual-Polarized Antenna Using Planar Quasi-Open-Sleeve Dipoles for Base Station Applications

, Xidian University, Xi’an, Shaanxi 710071, China Received 2 May 2015; Accepted 27 July 2015 Academic Editor: Herve Aubert Copyright © 2015 Guan-xi Zhang et al. This is an open access article

Genome-wide piggyBac transposon mediated screening reveals genes related to reprogramming

Scientists of State Key Laboratory of Agrobiotechnology 2015SKLAB6-15. Xi Zhang, Xinglin Wei, Yuanyuan Wu, Yuzhe Wang, Cheng Tan, Xiaoxiang Hu, Ning Li, Mario R. Capecchi and Sen Wu declare that they have no ... Li1, Mario R. Capecchi2, Sen Wu1& Xi Zhang, Xinglin Wei, and Yuanyuan Wu have contributed equally to this work. Electronic supplementary material The online version of this article (doi:10.1007/s13238

A Novel Supra-Brow Combined with Infra-Brow Lift Approach for Asian Women

Background Direct brow lift surgery remains popular among Asian women despite its disadvantages. The traditional direct brow lift by a supra-brow incision is not suitable for Asian women because of their unique facial features, such as higher eyebrows, wider upper eyelids, and more orbital fat. Therefore, we designed a novel brow lift technique via a supra-brow combined with an...

Potential of mean force between like-charged nanoparticles: Many-body effect

 & Zhi-Jie TanDepartment of Physics, School of Physics & Information Engineering, Jianghan University, Wuhan 430056, ChinaXiao-Long Zhu AuthorsSearch for Xi Zhang in:Nature Research journals • PubMed

Antifungal prophylaxis of patients undergoing allogenetic hematopoietic stem cell transplantation in China: a multicenter prospective observational study

Background Antifungal prophylaxis is currently regarded as the gold standard in situations with allo-genetic hematopoietic stem cell transplantation (allo-HSCT). However, the epidemiological information regarding prophylaxis of invasive fungal diseases (IFDs) is not clear in China. Methods We report the first large-scale (1053 patients) observational study of the prophylaxis and...

The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages

’ Contributions Hui juan Zhu designed the study and analyzed the experiment data. Su juan Li did the experiments and wrote the manuscript. Hui Pan supervised the clinical data. Naishi Li, Dian xi Zhang, Lin jie

The co-expression of MMP-9 and Tenascin-C is significantly associated with the progression and prognosis of pancreatic cancer

Background Matrix metalloproteinase-9 (MMP-9) and Tenascin-C (TN-C) have been shown to be involved in the metastasis of many tumors. The purpose of this study was to determine the relationship between the co-expression of these two molecules and the clinical prognosis of pancreatic cancer. Methods We investigated the expression of TN-C and MMP-9 in 103 pancreatic cancer tissues...

Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

 Lan He,3 Xue-zhi Hong,1 Fang Tian,2 Yan-hong Pan,1 Ling Liang,1 Xiao-xi Zhang,1,4 and Hai-lu Zhao1,2,4 1Diabetic Systems Medicine, Guangxi Key Laboratory of Excellence, Guilin Medical University ... data, and wrote the first daft. Jian Shen directed statistical analyses of the data and designed the study. Lan He, Xue-zhi Hong, Fang Tian, Yan-hong Pan, Ling Liang, and Xiao-xi Zhang analyzed and

The effect of mild induced hypothermia on outcomes of patients after cardiac arrest: a systematic review and meta-analysis of randomised controlled trials

Introduction Mild induced hypothermia (MIH) is believed to reduce mortality and neurological impairment after out-of-hospital cardiac arrest. However, a recently published trial demonstrated that hypothermia at 33 °C did not confer a benefit compared with that of 36 °C. Thus, a systematic review and meta-analysis of randomised controlled trials (RCTs) was made to investigate the...

Aerosol influence on energy balance of the middle atmosphere of Jupiter

Sciences, California Institute of Technology, Pasadena, California 91125, USAYuk L. Yung AuthorsSearch for Xi Zhang in:Nature Research journals • PubMed • Google ScholarSearch for Robert A. West in:Nature ... authors declare no competing financial interests. Corresponding author Correspondence to Xi Zhang. Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International

Histone acetylation: novel target for the treatment of acute lymphoblastic leukemia

. Press 4 Xi Zhang 0 3 0 Department of Hematology, Xinqiao Hospital, Third Military Medical University , Chongqing 400037 , People's Republic of China 1 Department of Pediatric, Keck School of Medicine

Different Antibody Response against the Coxsackievirus A16 VP1 Capsid Protein: Specific or Non-Specific

Coxsackievirus A16 (CA16) is one of the major causative agents of hand, foot, and mouth disease worldwide. The non-neutralizing antibody response that targets CA16 VP1 remains poorly elucidated. In the present study, antibody responses against CA16 VP1 in Shanghai blood donors and Shanxi individuals were analyzed by ELISA and inhibitory ELISA using five CA16 VP1 antigens: VP11...

MiR-129-2 functions as a tumor suppressor in glioma cells by targeting HMGB1 and is down-regulated by DNA methylation

MicroRNA (miRNA) dysregulation is causally related to cancer development and progression, and recent reports have revealed that DNA methylation constitutes an important mechanism for miRNA deregulation in cancer. MiR-129-2 has been reported to be down-regulated and functions as a tumor suppressor in a few human cancers. However, the involvement of miR-129-2 in the pathology of...