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114 papers found.
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Fracture rate in patients with myasthenia gravis: the general practice research database

Summary The aim of this study was to evaluate fracture risk after onset of myasthenia gravis using the UK General Practice Research Database. Overall fracture risk is not statistically increased compared with age- and gender-matched controls irrespective of glucocorticoid use, but was increased in those using antidepressants, anxiolytics or anticonvulsants. Introduction Myasthenia ...

The Arizona CDFS Environment Survey (ACES): A Magellan/IMACS Spectroscopic Survey of the Chandra Deep Field-South⋆

We present the Arizona CDFS Environment Survey (ACES), a recently completed spectroscopic redshift survey of the Chandra Deep Field-South (CDFS) conducted using the Inamori-Magellan Areal Camera and Spectrograph on the Magellan-Baade telescope. In total, the survey targeted 7277 unique sources down to a limiting magnitude of RAB = 24.1, yielding 5080 secure redshifts across the ∼30 ...

A systematic review of hip fracture incidence and probability of fracture worldwide

HP, Hiligsmann M, Kanis JA, Lau E, Lewiecki EM, Lips P, Lorenc R, McCloskey E, Ortolani S, Papaioannou A, Silverman S, Yoshimura N, and Szulc P 2 C. Cooper MRC Lifecourse Epidemiology Unit, University ... Cummings (China), B Abrahamsen (Denmark), CH Orces (Ecuador), R Sund and H Kroger (Finland), Kristin Siggeirsdottir and Vilmundur Gudnason (Iceland), D Dhanwal and C Cooper (India), Errol Hutagalung and

Automated morphological classification of Sloan Digital Sky Survey red sequence galaxies

In the last decade, the advent of enormous galaxy surveys has motivated the development of automated morphological classification schemes to deal with large data volumes. Existing automated schemes can successfully distinguish between early- and late-type galaxies and identify merger candidates, but are inadequate for studying detailed morphologies of red sequence galaxies. To fill ...

Dependence of galaxy quenching on halo mass and distance from its centre

We study the dependence of star formation quenching on galaxy mass and environment, in the Sloan Digital Sky Survey (SDSS; z ∼ 0.1) and the All-Wavelength Extended Groth Strip International Survey (AEGIS; z ∼ 1). It is crucial that we define quenching by low star formation rate rather than by red colour, given that one-third of the red galaxies are star forming. We address stellar ...

How does galaxy environment matter? The relationship between galaxy environments, colour and stellar mass at 0.4 < z < 1 in the Palomar/DEEP2 survey

We present a study characterizing the environments of galaxies in the redshift range of 0.4 < z < 1 based on data from the POWIR near-infrared imaging and DEEP2 spectroscopic redshift surveys, down to a stellar mass of log M*= 10.25 M⊙. Galaxy environments are measured in terms of nearest-neighbour densities as well as fixed aperture densities and kinematical and dynamical ...

Observational constraints on the physics behind the evolution of active galactic nuclei since z∼ 1

We explore the evolution with redshift of the rest-frame colours and space densities of active galactic nuclei (AGN) hosts (relative to normal galaxies) to shed light on the dominant mechanism that triggers accretion on to supermassive black holes as a function of cosmic time. Data from serendipitous wide-area XMM surveys of the Sloan Digital Sky Survey (SDSS) footprint (XMM/SDSS; ...

Available alternative incentives modulate anticipatory nucleus accumbens activation

A reward or punishment can seem better or worse depending on what else might have happened. Little is known, however, about how neural representations of an anticipated incentive might be influenced by the available alternatives. We used event-related FMRI to investigate the activation in the nucleus accumbens (NAcc), while we varied the available alternative incentives in a ...

Subtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report

of Geneva , 1211 Geneva 14, Switzerland 3 C. Cooper NIHR Musculoskeletal Biomedical Research Unit, University of Oxford , Oxford, UK 4 C. Cooper MRC Epidemiology Resource Centre, University of

A Post-Burst Afterdepolarization Is Mediated by Group I Metabotropic Glutamate Receptor-Dependent Upregulation of Cav2.3 R-Type Calcium Channels in CA1 Pyramidal Neurons

The excitability of hippocampal pyramidal neurons is regulated by activation of metabotropic glutamate receptors, an effect that is mediated by modulation of R-type calcium channels.

Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice Research Database

, University of Oxford , Oxford, UK 1 C. Cooper MRC Epidemiology Resource Centre, University of Southampton , Southampton, UK 2 ) INSERM U 953, Hpital Tenon, 4 rue de la Chine, 75020 Paris, France 3 J. Y

A reappraisal of generic bisphosphonates in osteoporosis

Sheffield Medical School , Beech Hill Road, Sheffield S10 2RX, UK 2 C. Cooper NIHR Musculoskeletal Biomedical Research Unit, University of Oxford , Oxford, UK 3 C. Cooper MRC Lifecourse Epidemiology Unit ... receives consulting fees, paid advisory boards and/or lecture fees from most companies concerned with bone disease. C Cooper receives consulting fees and paid advisory boards for Alliance for Better Bone

Output-Mode Transitions Are Controlled by Prolonged Inactivation of Sodium Channels in Pyramidal Neurons of Subiculum

Transitions between different behavioral states, such as sleep or wakefulness, quiescence or attentiveness, occur in part through transitions from action potential bursting to single spiking. Cortical activity, for example, is determined in large part by the spike output mode from the thalamus, which is controlled by the gating of low-voltage–activated calcium channels. In the ...

The epidemiology of osteonecrosis: findings from the GPRD and THIN databases in the UK

Epidemiology Resource Centre, University of Southampton , Southampton, UK 2 C. Cooper Rheumatology, University of Southampton , Southampton, UK 3 N. B. Watts Bone Health and Osteoporosis Center, University of

Use of proton pump inhibitors and risk of hip/femur fracture: a population-based case-control study

Summary Previous studies evaluated the association between proton pump inhibitor (PPI) use and subsequent fracture risk, but they showed ambiguous results. Therefore, the objective was to evaluate this association in a different study population. Our findings show that there is probably no causal relationship between PPI use and hip fracture risk. Introduction Previous studies ...

The role of environment in the mass–metallicity relation

Using a sample of 57 377 star-forming galaxies drawn from the Sloan Digital Sky Survey, we study the relationship between gas-phase oxygen abundance and environment in the local Universe. We find that there is a strong relationship between metallicity and environment such that more metal-rich galaxies favour regions of higher overdensity. Furthermore, this metallicity–density ...

Erratum to: Impact of nutrition on muscle mass, strength, and performance in older adults

, Belgium 2 J.-P. Bonjour 3 N. Yoshimura Department of Joint Disease Research, 22nd Century Medical and Research Center, The University of Tokyo , Tokyo , Japan 4 C. Cooper NIHR Musculoskeletal Biomedical ... Research Unit, Institute of Musculoskeletal Sciences, University of Oxford , Oxford , UK 5 C. Cooper MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital , Southampton

The DEEP3 Galaxy Redshift Survey: the impact of environment on the size evolution of massive early-type galaxies at intermediate redshift*,†

Using data drawn from the DEEP2 and DEEP3 Galaxy Redshift Surveys, we investigate the relationship between the environment and the structure of galaxies residing on the red sequence at intermediate redshift. Within the massive (10 < log10(M★/h−2 M⊙) < 11) early-type population at 0.4 < z < 1.2, we find a significant correlation between local galaxy overdensity (or environment) and ...

Genetically-Engineered Pig-to-Baboon Liver Xenotransplantation: Histopathology of Xenografts and Native Organs

Orthotopic liver transplantation was carried out in baboons using wild-type (WT, n = 1) or genetically-engineered pigs (α1,3-galactosyltransferase gene-knockout, GTKO), n = 1; GTKO pigs transgenic for human CD46, n = 7) and a clinically-acceptable immunosuppressive regimen. Biopsies were obtained from the WT pig liver pre-Tx and at 30 min, 1, 2, 3, 4 and 5 h post-transplantation. ...