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313 papers found.
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Genome-wide identification of the Jatropha curcas MYB family and functional analysis of the abiotic stress responsive gene JcMYB2

Background The MYB family is one of the most abundant transcription factor families in plants. MYB proteins are involved in plant development, abiotic stress tolerance, hormone signal transduction and disease resistance. Here we perform genome-wide identification of MYB family transcription factors in an energy plant J. curcas, including determining family composition...

Characterization of a pathway-specific activator of milbemycin biosynthesis and improved milbemycin production by its overexpression in Streptomyces bingchenggensis

Background Milbemycins, a group of 16-membered macrolides with potent anthelminthic and insecticidal activity, are produced by several Streptomyces and used widely in agricultural, medical and veterinary fields. Milbemycin A3 and A4, the main components produced by Streptomyces bingchenggensis, have been developed as an acaricide to control mites. The subsequent structural...

Water relations traits of C4 grasses depend on phylogenetic lineage, photosynthetic pathway, and habitat water availability

The repeated evolution of C4 photosynthesis in independent lineages has resulted in distinct biogeographical distributions in different phylogenetic lineages and the variants of C4 photosynthesis. However, most previous studies have only considered C3/C4 differences without considering phylogeny, C4 subtype, or habitat characteristics. We hypothesized that independent lineages of...

A novel MVA-mediated pathway for isoprene production in engineered E. coli

Background To deal with the increasingly severe energy crisis and environmental consequences, biofuels and biochemicals generated from renewable resources could serve as a promising alternative for replacing petroleum as a source of fuel and chemicals, among which isoprene (2-methyl-1,3-butadiene) in particular is of great significance in that it is an important platform chemical...

Intravoxel incoherent motion diffusion-weighted imaging in differentiating uterine fibroid from focal adenomyosis: initial results

Liu 0 0 Collaboration Scientist, MR Business Group, Healthcare Sector, Siemens Medical Solutions Ltd. , Shanghai , People's Republic of China 1 Department of Radiology, Obstetrics and Gynecology

Separation properties for infinite iterated function systems

In this paper, we study the infinite iterated function systems (IFSs) of contractive similitudes with overlaps. We extend the notions of the weak separation condition and the generalized finite type condition for finite IFSs to the infinite case. We show that for an infinite IFS of contractive similitudes the generalized finite type condition implies the weak separation condition...

Sigmoid Sinus Wall Reconstruction for Pulsatile Tinnitus Caused by Sigmoid Sinus Wall Dehiscence: A Single-Center Experience

. D101100050010031) to M.D. Zhen-Chang Wang, and the Capital Medical University of China (grant No. 13JL03) to M.D. Zhao-Hui Liu. The funders had no role in study design, data collection and analysis, decision to

Growth and metabolism of Beauveria bassiana spores and mycelia

Background Fungi are ubiquitous in nature and have evolved over time to colonize a wide range of ecosystems including pest control. To date, most research has focused on the hypocrealean genera Beauveria bassiana, which is a typical filamentous fungus with a high potential for insect control. The morphology and components of fungi are important during the spores germination and...

Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China

Chen Kuibiao Li Hui Liu Lei Luo Ming Wang ZhiCong Yang 0 Equal contributors Guangzhou Centre for Disease Control and Prevention , No. 1, Qide Rd, Jiahe, Baiyun, Guangzhou 510440 , China Background

A facile hydrothermal approach to the synthesis of nanoscale rare earth hydroxides

Nanosized rare earth (RE) hydroxides including La(OH)3, Nd(OH)3, Pr(OH)3, Sm(OH)3, Gd(OH)3, and Er(OH)3 with rod-like morphology are fabricated via a convenient hydrothermal approach. This strategy calls for the first preparation of metal complexes between RE precursors and dodecylamine (DDA) in water/ethanol mixture at room temperature and subsequent thermal decomposition at...

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease with cellular and molecular mechanisms yet to be fully described. Mutations in a number of genes including SOD1 and FUS are associated with familial ALS. Here we report the generation of induced pluripotent stem cells (iPSCs) from fibroblasts of familial ALS patients bearing SOD1 +/A272C and FUS +/G1566A...

lncRScan-SVM: A Tool for Predicting Long Non-Coding RNAs Using Support Vector Machine

Functional long non-coding RNAs (lncRNAs) have been bringing novel insight into biological study, however it is still not trivial to accurately distinguish the lncRNA transcripts (LNCTs) from the protein coding ones (PCTs). As various information and data about lncRNAs are preserved by previous studies, it is appealing to develop novel methods to identify the lncRNAs more...

The Mass Loss and Humification of Stumps and Roots in Masson Pine Plantations Based on Log File Records

Stumps account for a large proportion of coarse woody debris in managed forests, but their decay dynamics are poorly understood. The loss of mass and the degree of humification of the above-ground woody debris, below-ground woody debris, bark and root system (R1, 10 mm ≥ diameter > 0 mm; R2, 25 mm ≥ diameter >10 mm; 100 mm ≥ R3 > 25 mm; R4 > 100 mm) of Masson pine (Pinus...

Role of SIRT3 in Angiotensin II-induced human umbilical vein endothelial cells dysfunction

Background SIRT3, a member of the sirtuin family of NAD + -dependent deacetylases, resides primarily in the mitochondria and has been shown to deacetylate several metabolic and respiratory enzymes that regulate important mitochondrial functions. Previous researches show an important role of SIRT3 in regulating the production of reactive oxygen species (ROS), and highlight the...

Primary spontaneous pneumothorax: simultaneous treatment by bilateral non-intubated videothoracoscopy

OBJECTIVES Through a retrospective study, we assessed the feasibility and safety of simultaneous bilateral thoracoscopic wedge resection of blebs or bullae for the treatment of primary spontaneous pneumothorax (PSP) under thoracic epidural anaesthesia with spontaneous ventilation.

Elevated Levels of Serum Tumor Markers CEA and CA15-3 Are Prognostic Parameters for Different Molecular Subtypes of Breast Cancer

Background & Aims The utility of measuring carcinoembryonic antigen(CEA) and cancer antigen 15-3 (CA15-3) levels in patients with breast cancer remains controversial. The present study aims to investigate the prognostic value of preoperative serum CEA and CA15-3 levels in breast cancer patients. Methods Serum preoperative CEA and CA 15-3 concentration levels were measured in a...

Assessment of Vascularity in Hepatic Alveolar Echinococcosis: Comparison of Quantified Dual-Energy CT with Histopathologic Parameters

Purpose To investigate whether dual-energy computer tomography(DECT) could determine the angiographic vascularity of alveolar echinococcosis lesions by comparing the quantitative iodine concentration (IC) with the microvascular density (MVD). Material and Methods Twenty-five patients (16 men, 9 women; mean age, 40.9 ± 13.8 years) with confirmed hepatic alveolar echinococcosis...

Improving compound–protein interaction prediction by building up highly credible negative samples

Motivation: Computational prediction of compound–protein interactions (CPIs) is of great importance for drug design and development, as genome-scale experimental validation of CPIs is not only time-consuming but also prohibitively expensive. With the availability of an increasing number of validated interactions, the performance of computational prediction approaches is severely...

Long non-coding RNA AK027294 involves in the process of proliferation, migration, and apoptosis of colorectal cancer cells

This study is aimed to investigate the differentially expressed long non-coding RNAs (lncRNAs) in colorectal cancer and its potential biological function. Colorectal adenoma is the precancerous lesions of colorectal cancer, so in this study, we used colorectal adenoma as negative control. The global lncRNA expression profile in colorectal cancer and adenoma was evaluated by...