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A multi-state model for wind farms considering operational outage probability

reproduction in any medium, provided the original author(s) and the source are credited. Author Biographies Lin CHENG (M’05) was born in 1973. He received the B.S. degree from Tianjin University, Tianjin, China

Visual gene-network analysis reveals the cancer gene co-expression in human endometrial cancer

Background Endometrial cancers (ECs) are the most common form of gynecologic malignancy. Recent studies have reported that ECs reveal distinct markers for molecular pathogenesis, which in turn is linked to the various histological types of ECs. To understand further the molecular events contributing to ECs and endometrial tumorigenesis in general, a more precise identification of...

Prevalence of Integrase Strand Transfer Inhibitors (INSTI) Resistance Mutations in Taiwan

Antiretroviral therapy containing an integrase strand transfer inhibitor (INSTI) plus two NRTIs has become the recommended treatment for antiretroviral-naive HIV-1-infected patients in the updated guidelines. We aimed to determine the prevalence of INSTI-related mutations in Taiwan. Genotypic resistance assays were performed on plasma from ARV-naïve patients (N = 948), ARV...

The use of adjunctive traditional Chinese medicine therapy and survival outcome in patients with head and neck cancer: a nationwide population-based cohort study

Background: Traditional Chinese medicine (TCM) is widely used in the treatment of patients with several types of cancer. However, no large-scale clinical studies have evaluated whether TCM is associated with better survival in patients with head and neck cancer (HNC).

Hydrogen Absorption into Austenitic Stainless Steels Under High-Pressure Gaseous Hydrogen and Cathodic Charge in Aqueous Solution

Type 316L and Type 304 austenitic stainless steels, both deformed and non-deformed, were hydrogen charged cathodically in an aqueous solution as well as by exposure to high-pressure gaseous hydrogen in an attempt to identify suitable conditions of cathodic charge for simulating hydrogen absorption from gaseous hydrogen environments. Thermal desorption analysis (TDA) was conducted...

Innovative approach to the design of low-cost Zr-based BMG composites with good glass formation

-Lin Cheng & Guang ChenSchool of Materials Engineering, Nanjing Institute of Technology, Nanjing 211167, P R ChinaJia-Lin ChengCenter for Advanced Structural Materials, MEB Department, College of Science ... 117576Yi LiInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, P. R. ChinaYi Li AuthorsSearch for Jia-Lin Cheng in:Nature Research journals • PubMed • Google ScholarSearch for Guang

Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss

Ministry of Science and Technology (Taipei, Taiwan; grants NSC 102-2325-B-006-002- for Hua-Lin Wu, and MOST 104-2320-B-037-026 – for Tsung-Lin Cheng). This research was, in part, supported by the Ministry of ... These authors contributed equally to this work. AffiliationsDepartment of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung, TaiwanTsung-Lin Cheng, Chau-Zen Wang & Mei-Ling

Risk Factors for Renal Scarring and Deterioration of Renal Function in Primary Vesico-Ureteral Reflux Children: A Long-Term Follow-Up Retrospective Cohort Study

Background and Purpose The aim was to identify the risk factors for renal scarring and deteriorating renal function in children with primary vesico-ureteral reflux (VUR). Materials and Methods Patients with primary VUR admitted to the National Cheng Kung University Hospital were retrospectively analyzed. The outcomes were renal scarring, assessed by technetium-99 m...

Tumor Vascularity and Glucose Metabolism Correlated in Adenocarcinoma, but Not in Squamous Cell Carcinoma of the Lung

Background/Objectives To prospectively examine the relation between tumor vascularity and glucose metabolism in adenocarcinoma (AC) and squamous cell carcinoma(SCC) of the lung by using positron emission tomography/computed tomography (PET/CT) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Materials and Methods Forty-one consecutive patients with...

Toll-Like Receptor 4 Is Essential in the Development of Abdominal Aortic Aneurysm

Toll-like receptor (TLR) family plays a key role in innate immunity and various inflammatory responses. TLR4, one of the well-characterized pattern-recognition receptors, can be activated by endogenous damage-associated molecular pattern molecules such as high mobility group box 1 (HMGB1) to sustain sterile inflammation. Evidence suggested that blockade of TLR4 signaling may...

Identification of Mur34 as the Novel Negative Regulator Responsible for the Biosynthesis of Muraymycin in Streptomyces sp. NRRL30471

Background Muraymycin, a potent translocase I (MraY) inhibitor, is produced by Streptomyces sp. NRRL30471. The muraymycin gene cluster (mur) was recently cloned, and bioinformatic analysis of mur34 revealed its encoding product exhibits high homology to a large family of proteins, including KanI and RacI in individual biosynthetic pathway of kanamycin and ribostamycin. However...

Rapid and high-efficiency generation of mature functional hepatocyte-like cells from adipose-derived stem cells by a three-step protocol

The generation of functional hepatocytes is a major challenge for regenerative medicine and drug discovery. Here we show a method that facilitates generation of induced functional hepatocytes (iHeps) from adipose-derived stem cells (ADSCs) within 9 days. iHeps express hepatocytic gene programs and display functions characteristic of mature hepatocytes, including cytochrome P450...

Treatment Outcomes of Adenotonsillectomy for Children with Obstructive Sleep Apnea: A Prospective Longitudinal Study

To evaluate the efficacy of adenotonsillectomy (AT) in the treatment of children with obstructive sleep apnea (OSA) in a 3-y prospective, longitudinal study with analysis of risk factors of recurrence of OSA.

Diversity and Antimicrobial Activity of Culturable Endophytic Fungi Isolated from Moso Bamboo Seeds

Bamboos, regarded as therapeutic agents in ethnomedicine, have been used to inhibit inflammation and enhance natural immunity for a long time in Asia, and there are many bamboo associated fungi with medical and edible value. In the present study, a total of 350 fungal strains were isolated from the uncommon moso bamboo (Phyllostachys edulis) seeds for the first time. The...

Improving early infant HIV diagnosis in Kenya: study protocol of a cluster-randomized efficacy trial of the HITSystem

Background Early infant diagnosis among human immunodeficiency virus (HIV)-exposed infants is a critical component of prevention of mother-to-child transmission programs. Barriers to early infant diagnosis include poor uptake, low retention at designated re-testing intervals, delayed test results, passive systems of communication, and poor linkage to treatment. This study will...

Myxofibrosarcoma of the sinus piriformis: case report and literature review

Myxofibrosarcoma is a common sarcoma in the extremities of older people, but is rare in the head and neck region. Here, we report the case of a 42-year-old male patient in whom myxofibrosarcoma generated from the sinus piriformis. Histopathologically, the tumor was characterized by spindle cellular proliferation with moderate cellular density in fibromyxoid stroma...

Dengue Virus Infection Causes the Activation of Distinct NF-κB Pathways for Inducible Nitric Oxide Synthase and TNF-α Expression in RAW264.7 Cells

University, Taipei 110, Taiwan Received 29 October 2014; Revised 14 April 2015; Accepted 19 May 2015 Academic Editor: Dennis D. Taub Copyright © 2015 Yi-Lin Cheng et al. This is an open access article

Theoretical analysis of a method for segmented heat exchanger design

In the process of the design of heat exchangers, it is difficult to establish the factors governing the optimal points of the design objective functions due to the contradictions and uncertainties of the design objectives. The variation of fluid properties is one of the main factors causing this type of uncertainty. Conventional design methods have not completely solved these...

A Comparison of the Microwave Photoconductivity Decay and Open-Circuit Voltage Decay Lifetime Measurement Techniques for Lifetime-Enhanced 4H-SiC Epilayers

This work compares the optical microwave photoconductivity decay (μPCD) and electrical open-circuit voltage decay (OCVD) techniques for measuring the ambipolar carrier lifetime in 4H-silicon carbide (4H-SiC) epitaxial layers. Lifetime measurements were carried out by fabricating P+/intrinsic/N+ (PiN) diodes on 100-μm-thick, 1 × 1014 cm−3 to 4.5 × 1014 cm−3 doped N-type 4 H-SiC...

Job autonomy, its predispositions and its relation to work outcomes in community health centers in Taiwan

It has been debated that employees in a government or public ownership agency may perceive less need for growth opportunities or high-powered incentives than is the case for employees in private organizations. This study examined employees’ job autonomy in government-run community health centers, its predispositions and its relation to their work outcomes. A cross-sectional study...