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118 papers found.
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Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study

European Community (5th Framework Programme) to Prof. Paolo Vineis (Grant QLK4CT199900927); and a grant of the Compagnia di San Paolo to the ISI Foundation. All authors are independent form founders ... , Paolo Vineis. Analysis and interpretation of data: Valentina Gallo, Nicola Vanacore, H. Bas Bueno-de-Mesquita, Roel Vermeulen, Carol Brayne, Petra A. Wark, Heather A Ward, Pietro Ferrari, Mazda Jenab

Compliance with clinical practice guidelines for breast cancer treatment: a population-based study of quality-of-care indicators in Italy

Background It has been documented that variations exist in breast cancer treatment despite wide dissemination of clinical practice guidelines. The aim of this population-based study was to evaluate the impact of regional guidelines (Piedmont guidelines, PGL) for breast cancer diagnosis and treatment on quality-of-care indicators in the Northwestern Italian region of Piedmont...

STrengthening the Reporting of OBservational studies in Epidemiology – Molecular Epidemiology (STROBE-ME): An extension of the STROBE statement

Advances in laboratory techniques have led to a rapidly increasing use of biomarkers in epidemiological studies. Biomarkers of internal dose, early biological change, susceptibility and clinical outcomes are used as proxies for investigating interactions between external and / or endogenous agents and body components or processes. The need for improved reporting of scientific...

Response Re: Markers of DNA Repair and Susceptibility to Cancer in Humans: an Epidemiologic Review

. We hope that other eminent scientists will join their efforts to develop appropriate assays for DNA repair. MARIANNE BERWICK PAOLO VINEIS (1) Berwick M, Vineis P. Markers of DNA repair and

STrengthening the Reporting of OBservational studies in Epidemiology – Molecular Epidemiology (STROBE-ME): An Extension of the STROBE Statement

Paolo Vineis 0 0 1 Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London , London , United Kingdom , 2 Social and Environmental Health Research, London School of

Expectations and challenges stemming from genome-wide association studies

There are considerable expectations about the ability of genome-wide association (GWA) studies to make exciting discoveries about the role of genes in common diseases. GWA studies may allow researchers to identify causal pathways that have not been unveiled before, thus opening new avenues to disease understanding, prevention and therapy. However, there are still many open...

XRCC3 and XPD/ERCC2 Single Nucleotide Polymorphisms and the Risk of Cancer: A HuGE Review

associations are weak and presently do not justify screening. This research was made possible by a grant from the Compagnia di San Paolo (Progetto Oncologia) to Dr. Paolo Vineis and a grant from the

Prediagnostic immunoglobulin E levels and risk of chronic lymphocytic leukemia, other lymphomas and multiple myeloma-results of the European Prospective Investigation into Cancer and Nutrition

 Sánchez Soledad Sánchez Signe Borgquist Salma Butt Beatrice Melin Florentin Späth Sabina Rinaldi Paul Brennan Rachel S.Kelly Elio Riboli Paolo Vineis Rudolf Kaaks © The Author 2014. Published by Oxford

Occult HCV Infection: An Unexpected Finding in a Population Unselected for Hepatic Disease

Background Occult Hepatitis C virus (HCV) infection is a new pathological entity characterized by presence of liver disease and absence or very low levels of detectable HCV-RNA in serum. Abnormal values of liver enzymes and presence of replicative HCV-RNA in peripheral blood mononuclear cells are also observed. Aim of the study was to evaluate occult HCV occurrence in a...

Proteome characterization of a human urothelial cell line resistant to the bladder carcinogen 4-aminobiphenyl

Background The aromatic amine 4-aminobiphenyl (4-ABP) is an environmental and occupational contaminant known to be a major etiological agent of human bladder cancer. 4-ABP metabolites are able to form DNA adducts that may induce mutations and initiate bladder carcinogenesis. Cells exposed to 4-ABP may develop resistance to the carcinogen. The aim of the present study was to...

Metabolomic profiles of hepatocellular carcinoma in a European prospective cohort

Heiner Boeing Pagona Lagiou Christina Bamia Dimitrios Trichopoulos Domenico Palli Valeria Pala Salvatore Panico Rosario Tumino Paolo Vineis H. Bas Bueno-de-Mesquita Petra H. Peeters Elisabete Weiderpass

A Field Synopsis on Low-Penetrance Variants in DNA Repair Genes and Cancer Susceptibility

, University of Ioannina School of Medicine , Ioannina 45110, Greece ( 1 Paolo Vineis, Maurizio Manuguerra, Fotini K. Kavvoura, Simonetta Guarrera, Alessandra Allione, Fabio Rosa, Alessandra Di Gregorio, Silvia

Evidence of gene–gene interactions in lung carcinogenesis in a large pooled analysis

To test the hypothesis of interaction among genetic variants in increasing the individual risk of cancer, we have studied the cumulative effect on lung cancer risk of variants in three metabolic genes, CYP1A1, GSTM1 and GSTT1, which are involved in the metabolism of the tobacco smoke constituents and environmental contaminants, polycyclic aromatic hydrocarbons and of other lung...

Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking

London, St Mary’s Campus, Norfolk Place, W2 1PG, UKMarc Chadeau-Hyam, Paolo Vineis, Rachel Kelly & Toby J. AthersuchDivision of Environmental Epidemiology, Institute for Risk Assessment Sciences, Utrecht ... • Google ScholarSearch for Paolo Vineis in:Nature Research journals • PubMed • Google ScholarSearch for Soterios A. Kyrtopoulos in:Nature Research journals • PubMed • Google Scholar Contributions S.A.K

Circulating 25-Hydroxyvitamin D3 in Relation to Renal Cell Carcinoma Incidence and Survival in the EPIC Cohort

Severi, Paolo Vineis); Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany (Tilman Kühn, Verena Katzke); Public Health Directorate, Asturias, Spain (Ramón Alonso de la Torre ... of Public Health, Imperial College London, London, United Kingdom (Paolo Vineis, H. Bas Bueno-de-Mesquita, Petra H. Peeters, Neil Murphy, Elio Riboli); Dopartimento di Medicina Clinica e Sperimentale

Baseline and lifetime alcohol consumption and risk of differentiated thyroid carcinoma in the EPIC study

¨hn Verena A Katze Heiner Boeing Antonia Trichopoulou Christos Tsironis Pagona Lagiou Domenico Palli Valeria Pala Salvatore Panico Rosario Tumino Paolo Vineis Bueno-de-Mesquita Petra H Peeters Anette

Plasma Elaidic Acid Level as Biomarker of Industrial Trans Fatty Acids and Risk of Weight Change: Report from the EPIC Study

Background Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and...

Pre-diagnostic concordance with the WCRF/AICR guidelines and survival in European colorectal cancer patients: a cohort study

Genevieve Buckland Mara Jos Snchez Miren Dorronsoro Carmen Navarro Aurelio Barricarte Timothy J Key Antonia Trichopoulou Christos Tsironis Pagona Lagiou Giovanna Masala Valeria Pala Rosario Tumino Paolo ... Vineis 1 Salvatore Panico H Bas Bueno-de-Mesquita 1 Peter D Siersema Bodil Ohlsson Karin Jirstrm Maria Wennberg Lena M Nilsson Elisabete Weiderpass Tilman Khn Verena Katzke Kay-Tee Khaw Nick J Wareham Anne

Intake of fruits and vegetables and polymorphisms in DNA repair genes in bladder cancer

The objective is to investigate the relationships between fruit and vegetable intake, DNA repair gene polymorphisms and the risk of bladder cancer. We have analyzed a hospital-based case–control study of 266 individuals with incident, histologically confirmed bladder cancer diagnosed between 1994 and 2003. Controls (n = 193) were patients treated for benign diseases recruited...