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Determination of influenza B identity and potency in quadrivalent inactivated influenza vaccines using lineage-specific monoclonal antibodies

Co-circulation of two antigenically and genetically distinct lineages of influenza B virus, represented by prototype viruses B/Victoria/2/1987 and B/Yamagata/16/1988, has led to the development of quadrivalent influenza vaccines that contain two influenza B antigens. The inclusion of two influenza B antigens presents challenges for the production and regulation of inactivated ...

Multiple statuses of through-wall human being detection based on compressed UWB radar data

Ultra-wideband (UWB) radar is one of the most favorable methods for through-wall human detection due to its strong penetration ability in many common non-metallic obstructions. The paper proposed the residual subspace projection method for multiple statuses of through-wall human being detection behind. And the compressed sensing method was presented to collect incomplete UWB radar ...

Special issue on resilience in steel structures

Structures”. Guest Editors Wei Wang Professor, Tongji University, China E-mail: Tak-Ming Chan Assistant Professor, The Hong Kong Polytechnic University, Hong Kong SAR, China Yunfeng Zhang Professor, University

Safety and tolerability of high-dose ulinastatin after 2-hour intravenous infusion in adult healthy Chinese volunteers: A randomized, double-blind, placebo-controlled, ascending-dose study

Ulinastatin, is a broad-spectrum protease inhibitor purified from human urine, inhibits endogenous proteases such as trypsin, α-chymotrypsin, hyaluronidase, and plasmin. It is widely being used at increasingly higher doses for the treatment of acute or chronic pancreatitis, severe infection, and acute organ failure. We aimed to evaluate the safety and tolerability of high-dose ...

Effect of solution treatment on microstructure and hardness of rheo-forming AZ91-Y alloy

Architectural Engineering, Jinggangshan University , Ji'an 343009 , China 1 , and Wen-xian Huang 2 Zhi-wei Wang 3 Hong Yan Male , born in 1962, Ph. D , Prof. Research interests: semi-solid processing of magnesium

Hepatocyte nuclear factor 1α downregulates HBV gene expression and replication by activating the NF-κB signaling pathway

The role of hepatocyte nuclear factor 1α (HNF1α) in the regulation of gene expression and replication of hepatitis B virus (HBV) is not fully understood. Previous reports have documented the induction of the expression of viral large surface protein (LHBs) by HNF1α through activating viral Sp1 promoter. Large amount of LHBs can block the secretion of hepatitis B surface antigen ...

iTRAQ-Based Proteomics Reveals Novel Biomarkers for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a gradual lung disease with a survival of less than 5 years post-diagnosis for most patients. Poor molecular description of IPF has led to unsatisfactory interpretation of the pathogenesis of this disease, resulting in the lack of successful treatments. The objective of this study was to discover novel noninvasive biomarkers for the diagnosis ...

Interocular symmetry of the peripapillary choroidal thickness and retinal nerve fibre layer thickness in healthy adults with isometropia

Background The aim of this study was to determine the interocular differences in the peripapillary retinal nerve fibre layer (RNFL), peripapillary choroidal thickness (PCT) and subfoveal choroidal thickness (SFCT) in healthy adults with isometropia, using enhanced depth imaging optical coherence tomography (EDI SD-OCT). Methods One hundred healthy Chinese adults with spherical ...

Lipedematous alopecia: clinical and histological analysis of the first male Chinese

Background Lipedematous alopecia (LA) is a rare disorder clinically characterized by a thick boggy scalp and varying severity of hair loss, which primarily occurs in black female adults. In this study, we reported one male adult Chinese diagnosed with lipedematous alopecia for the first time. Case presentation A Chinese male, aged 20 years old, admitted to Shandong Provincial ...

\(B_c\rightarrow B_{sJ}\) form factors and \(B_c\) decays into \(B_{sJ}\) in covariant light-front approach

We suggest to study the \(B_{s}\) and its excitations \(B_{sJ}\) in the \(B_c\) decays. We calculate the \(B_c\rightarrow B_{sJ}\) and \(B_c\rightarrow B_{J}\) form factors within the covariant light-front quark model, where the \(B_{sJ}\) and \(B_{J}\) denote an s-wave or p-wave \(\bar{b}s\) and \(\bar{b}d\) meson, respectively. The form factors at \(q^2=0\) are directly computed ...

Size effect of Au/PAMAM contrast agent on CT imaging of reticuloendothelial system and tumor tissue

Polyamidoamine (PAMAM)-entrapped Au nanoparticles were synthesized with distinct sizes to figure out the size effect of Au-based contrast agent on CT imaging of passively targeted tissues. Au/PAMAM nanoparticles were first synthesized with narrow distribution of particles size of 22.2 ± 3.1, 54.2 ± 3.7, and 104.9 ± 4.7 nm in diameters. Size effect leads no significant difference on ...

Dexmedetomidine sedation reduces atrial fibrillation after cardiac surgery compared to propofol: a randomized controlled trial

Background Atrial fibrillation occurs frequently in patients following cardiac surgery and can be a cause of increased morbidity and mortality. The use of dexmedetomidine to prevent atrial fibrillation is unclear. The present study was designed to evaluate the effect of dexmedetomidine sedation on the incidence of atrial fibrillation after cardiac surgery. Methods Upon arrival to ...

Comparison of Two Cap Thickness in Small Incision Lenticule Extraction: 100μm versus 160μm

Purpose To compare the changes of biomechanical properties, endothelial cell density (ECD), and posterior corneal elevation (PCE) after femtosecond small incision lenticule extractions (SMILEs) with 100μm versus 160μm cap thicknesses. Methods A total of 12 rabbits were randomly assigned into two groups of 6 each. SMILE was performed at a depth of either 160μm (160-cap group) or ...

Association between complicated liver cirrhosis and the risk of hepatocellular carcinoma in Taiwan

Chuah. Project administration: Chih-Ming Liang, Ming-Kun Ku, Pin-I Hsu. Resources: Kai-Lung Tsai, Ming-Kun Ku, Jiunn-Wei Wang, Pin-I Hsu, Seng-Kee Chuah. Software: Kai-Lung Tsai, Ming-Kun Ku, Jiunn-Wei ... Wang, Shih-Cheng Yang. Supervision: Deng-Chyang Wu, Seng-Kee Chuah. Validation: Jiunn-Wei Wang. Visualization: Jiunn-Wei Wang, Shih-Cheng Yang. Writing ± original draft: Tsung-Hsing Hung. Writing

Comparison of Delta-Shape Anastomosis and Extracorporeal Billroth I Anastomosis after Laparoscopic Distal Gastrectomy for Gastric Cancer: A Systematic Review with Meta-Analysis of Short-Term Outcomes

Objective The aim of this systematic review and meta-analysis is to evaluate the safety and relative benefits of delta-shape anastomosis (DA) by comparing to conventional laparoscopy-assisted distal gastrectomy with Billroth I gastroduodenostomy (LADG BI). Methods Studies and relevant literature regarding DA versus LADG BI were searched in the electronic databases. Operation time, ...

Model updating mechanism of concept drift detection in data stream based on classifier pool

In data stream, concept drift often occurs in an unpredictable way, the classifier model which was learned from previous data is not accurate to the current data, so regular updating of the model is necessary. Moreover, updating too frequently will cause a negative impact on the clustering accuracy and the analysis of subsequent data. This paper proposed a model-updating mechanism ...

Facing the challenges in ophthalmology clerkship teaching: Is flipped classroom the answer?

Recent reform of medical education highlights the growing concerns about the capability of the current educational model to equip medical school students with essential skills for future career development. In the field of ophthalmology, although many attempts have been made to address the problem of the decreasing teaching time and the increasing load of course content, a growing ...

Production of \(a_1\) in heavy meson decays

Eur. Phys. J. C Production of a1 in heavy meson decays Wei Wang 0 1 Zhen-Xing Zhao 1 0 State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences

Visual and noxious electrical stimulus-evoked membrane-potential responses in anterior cingulate cortical neurons

Wang 2 3 0 Equal contributors 1 Institute and Key Laboratory of Brain Functional Genomics of Shanghai and Chinese Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, School of

Cytokinin-Regulated Sucrose Metabolism in Stay-Green Wheat Phenotype

A wheat stay-green mutant, tasg1, was observed to exhibit significantly delayed senescence in the late developmental stage. The photosynthetic capacity of the flag leaf was greater in tasg1 than in wild type (WT) plants. In addition, the grain volume of tasg1 was significantly higher than that of WT at the early filling stage. The content of various cytokinins (CKs) in the grain ...