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Mild Joint Symptoms Are Associated with Lower Risk of Falls than Asymptomatic Individuals with Radiological Evidence of Osteoarthritis

Osteoarthritis (OA) exacerbates skeletal muscle functioning, leading to postural instability and increased falls risk. However, the link between impaired physical function, OA and falls have not been elucidated. We investigated the role of impaired physical function as a potential mediator in the association between OA and falls. This study included 389 participants [229 fallers...

Thioxopyrimidine in Heterocyclic Synthesis I: Synthesis of Some Novel 6-(Heteroatom-substituted)-(thio)pyrimidine Derivatives

and Maw Cherng Suen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

Glue Ear, Hearing Loss and IQ: An Association Moderated by the Child’s Home Environment

EJ , Dewey C , Pryce K , Maw AR ( 2000 ) The frequency of otitis media with effusion in British pre-school children: a guide for treatment . ALSPAC Study Team. Clin Otolaryngol Allied Sci . 25 : 485

Neuroprotective effects of the mood stabilizer lamotrigine against glutamate excitotoxicity: roles of chromatin remodelling and Bcl-2 induction

Leng 0 Emily Bame Fessler 0 De-Maw Chuang 0 0 Molecular Neurobiology Section, National Institute of Mental Health, National Institutes of Health , Bethesda, MD , USA Lamotrigine (LTG), a phenyltriazine

An individually-tailored multifactorial intervention program for older fallers in a middle-income developing country: Malaysian Falls Assessment and Intervention Trial (MyFAIT)

Background In line with a rapidly ageing global population, the rise in the frequency of falls will lead to increased healthcare and social care costs. This study will be one of the few randomized controlled trials evaluating a multifaceted falls intervention in a low-middle income, culturally-diverse older Asian community. The primary objective of our paper is to evaluate...

Photoreceptor Degeneration in Two Mouse Models for Congenital Stationary Night Blindness Type 2

on experimental animal welfare (Tierschutzgesetz; AZ 820-8791.2.63). Animals DEx1417 and I756T mutants were generated by Dr. Marion Maw, and are available through the Jackson Laboratory (stock

Neonatal extravasation injury: prevention and management in Australia and New Zealand-a survey of current practice

Background Extravasation injury remains an important cause of iatrogenic injury in neonatal intensive care. This study aims to describe the current approach to extravasation injury (EI) prevention and management in Neonatal Intensive Care Units (NICUs) in Australia and New Zealand. Methods A literature review regarding extravasation injury in the newborn was carried out to inform...

UNDERSTANDING THE DEVELOPMENT OF SUBSTANTIVE AND DYNAMIC CAPABILITIES IN NEW VENTURES: THE ROLE OF FOUNDER PERSONALITY AND EXPERIENCE (SUMMARY)

administrator of Digital Knowledge at Babson. For more information , please contact Recommended Citation De Cock, Robin; Clarysse, Bart; and Foo, Maw Der (2011) "UNDERSTANDING THE DEVELOPMENT OF SUBSTANTIVE AND ... IN NEW VENTURES: THE ROLE OF FOUNDER PERSONALITY AND EXPERIENCE Robin De Cock, University of Ghent, Belgium Bart Clarysse, University of Ghent, Belgium Maw Der Foo, University of Colorado, USA

Systematic review of robotic liver resection

resection is comparable to conventional laparoscopic liver resection. Acknowledgments The authors thank Dr. Zenichi Morise for providing useful information. Disclosures Drs. Cheng-Maw Ho, Go Wakabayashi

Detecting metabolites of different transition metallithospermate B complexes after intravenous injection in rats

metal-LSB complexes; Wen-Ying CHEN guided the animal experiments; Chung-Yu CHEN and Maw-Rong LEE performed the LS/MS/MS analysis; Jason TC TZEN and Ying-Jie CHEN wrote the paper. References 1. Skou ... , National Chung Hsing University, Taichung 40227, Taiwan, ChinaChung-Yu Chen & Maw-Rong LeeSchool of Chinese Medicine, China Medical University, Taichung 40402, Taiwan, ChinaTzyy-Rong Jinn & Jason Tc

FEELING, THINKING, DOING: AFFECTIVE INFLUENCES ON GOAL PROGRESS AND ENTREPRENEURIAL EFFORTS

Marilyn A. Uy 0 1 2 Maw-Der Foo 0 This Paper is brought to you for free and open access by the Entrepreneurship at Babson at Digital Knowledge at Babson. It has been accepted for inclusion in

Sensitivity analysis of dynamic biological systems with time-delays

Background Mathematical modeling has been applied to the study and analysis of complex biological systems for a long time. Some processes in biological systems, such as the gene expression and feedback control in signal transduction networks, involve a time delay. These systems are represented as delay differential equation (DDE) models. Numerical sensitivity analysis of a DDE...

Phylodynamic analysis of the canine distemper virus hemagglutinin gene

Background Canine distemper (CD) is one of the most contagious and lethal viral diseases in dogs. Despite the widespread use of vaccines, the prevalence of the CD virus (CDV) has increased at an alarming rate in recent years. In this phylodynamic study, we investigated the spatiotemporal modes of dispersal, viral demographic trends, and effectiveness of vaccines for CDV. A total...

Multi-objective optimization of enzyme manipulations in metabolic networks considering resilience effects

Background Improving the synthesis rate of desired metabolites in metabolic systems is one of the main tasks in metabolic engineering. In the last decade, metabolic engineering approaches based on the mathematical optimization have been used extensively for the analysis and manipulation of metabolic networks. Experimental evidence shows that mutants reflect resilience phenomena...

Lysophosphatidic Acid Alters the Expression Profiles of Angiogenic Factors, Cytokines, and Chemokines in Mouse Liver Sinusoidal Endothelial Cells

Background and Aims Lysophosphatidic acid (LPA) is a multi-function glycerophospholipid. LPA affects the proliferation of hepatocytes and stellate cells in vitro, and in a partial hepatectomy induced liver regeneration model, the circulating LPA levels and LPA receptor (LPAR) expression levels in liver tissue are significantly changed. Liver sinusoidal endothelial cells (Lsecs...

Development and implementation of a mini-Clinical Evaluation Exercise (mini-CEX) program to assess the clinical competencies of internal medicine residents: from faculty development to curriculum evaluation

Background The mini-CEX is a valid and reliable method to assess the clinical competencies of trainees. Its data could be useful for educators to redesign curriculum as a process of quality improvement. The aim of this study was to evaluate a mini-CEX assessment program in our internal medicine residency training. We investigated the impact of mini-CEX workshops as a faculty...

Relationships Between the Importation, Transmission, and Nosocomial Infections of Methicillin-Resistant Staphylococcus aureus: An Observational Study of 112 Veterans Affairs Medical Centers

Background. The study of hospital methicillin-resistant Staphylococcus aureus (MRSA) epidemiology is complicated by its transmissibility. Our objective was to understand how MRSA importation and transmission influence MRSA nosocomial infections in Veterans Affairs Medical Centers (VAMCs). Methods. We performed hospital-level analyses of acute-care MRSA admission prevalence...

An Increase in CD3+CD4+CD25+ Regulatory T Cells after Administration of Umbilical Cord-Derived Mesenchymal Stem Cells during Sepsis

Sepsis remains an important cause of death worldwide, and vigorous immune responses during sepsis could be beneficial for bacterial clearance but at the price of collateral damage to self tissues. Mesenchymal stem cells (MSCs) have been found to modulate the immune system and attenuate sepsis. In the present study, MSCs derived from bone marrow and umbilical cord were used and...