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Effect of the Number of Pregnancies on Mortality Risk in HIV-Infected Women: a Prospective Cohort Study in Rural KwaZulu-Natal, South Africa

We investigated whether mortality risk increases with the number of full-term pregnancies in HIV-infected women. Our study is based on data from the ACDIS cohort, collected in rural KwaZulu-Natal, South Africa. Mortality risk for different number of pregnancies in HIV-infected women was analyzed using Cox proportional hazards model. The risk of TB or AIDS mortality in HIV...

Prognostic value of posttreatment 18F-FDG PET/CT and predictors of metabolic response to therapy in patients with locally advanced cervical cancer treated with concomitant chemoradiation therapy: an analysis of intensity- and volume-based PET parameters

PurposeTo investigate the prognostic value of posttreatment 18F-FDG PET/CT in patients with locally advanced cervical cancer (LACC) treated with concomitant chemoradiation therapy (CCRT). The secondary aim was to assess the possible role of intensity-based and volume-based PET parameters including SUVmax, SUVmean, MTV and TLG, and clinical parameters including age, pathology...

Transforming growth factor-β1 gene promoter -509C/T polymorphism in association with expression affects colorectal cancer development and depends on gender

It is widely known that sporadic colorectal cancer (CRC) is age-related diseases with higher incidence rate among men. Transforming growth factor-β1 (TGF-β1) is a major immune regulatory cytokine with a great impact and dual role in gastrointestinal carcinogenesis. In this context, the aim of the study was to explore the role of circulating TGF-β1 and the -509C/T functional...

Construction and Validation of the Touch Experiences and Attitudes Questionnaire (TEAQ): A Self-report Measure to Determine Attitudes Toward and Experiences of Positive Touch

Despite growing interest in the beneficial effects of positive touch experiences throughout our lives, and individual differences in how these experiences are perceived, there is not yet available a contemporary self-report measure of touch experiences and attitudes, for which the factor structure has been validated. This article describes four studies carried out during the...

B-space: dynamic management and assurance of open systems of systems

Connected cars, freely configurable operating rooms, or autonomous harvesting fleets: dynamically emerging open systems of systems will shape a new generation of systems opening up a vast potential for new kinds of applications. In light of the hard-to-predict structure and behavior of such systems, assuring their safety will require some disruptive changes of established safety...

Transient Rheological Behavior of Semisolid SEED-Processed 7075 Aluminum Alloys in Rapid Compression

The transient rheological behavior and microstructure evolution of semisolid SEED-processed 7075 aluminum alloys were studied using the rapid compression tests. The effects of the TiB2 grain refinement on the grain morphology and size of semisolid slurries were investigated. Results indicated that the grain refiner could reduce the grain size and improve the globularity of α-Al...

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine

A 62-year-old woman who underwent surgery to treat pancreatic cancer provided written, informed consent to undergo adjuvant therapy with gemcitabine, tegafur, and uracil. However, this was stopped after only 14 days due to Grade 4 neutropenia. She was then started on vaccine therapy with Survivin 2B peptide (SVN-2B) including IFA and INF-α. Although metastatic lung tumors were...

Genome-wide identification and expression profiling of the auxin response factor (ARF) gene family in physic nut

Auxin response factors (ARF) are important transcription factors which mediate the transcription of auxin responsive genes by binding directly to auxin response elements (AuxREs) found in the promoter regions of these genes. To date, no information has been available about the genome-wide organization of the ARF transcription factor family in physic nut. In this study, 17 ARF...

Prolonged Detection of Zika Virus Nucleic Acid Among Symptomatic Pregnant Women: A Cohort Study

A prospective cohort of women with reverse transcription polymerase chain reaction (RT-PCR) confirmed Zika virus infection aged 18–39 years in Puerto Rico found that pregnant women have about a 3-fold longer estimated median detection of Zika virus RNA in serum, which can increase definitive diagnosis of infection and facilitate timely and appropriate clinical management.

Head Teachers’ Characteristics and Instructional Leadership in Curriculum Implementation in Secondary Schools, Siaya County, Kenya

Personal or background characteristics can influence head teachers instructional leadership in schools. This study investigated the relationship, if any, between the head teacher’s instructional leadership and the head teacher’s background variables such as education/ professional qualification, gender, age,p and teaching experience in the implementation of curriculum...

Référents, Sens Et Effets De Sens De L’énoncé « Vieux Père, Voilà Ton Petit / Tes Petits » Dans Le Français De Côte d’Ivoire

In Côte d'Ivoire, as elsewhere in the French-speaking world, the French language is characterized by a constant movement on the lexical and semantic level. This situation, which testifies to the dynamism of French in a foreign context, is a constant source of thought for linguists. The present study focuses on the statement Old Father, this is your little one, a recurring...

Entrepreneurial NPOs in Russia: Rationalizing the Mission

Nonprofit organizations in Russia are introducing for-profit activities as a means of gaining autonomy from external donors, and as instruments of strategic planning and sustainable development. This study focuses on organizations that work with welfare provision and explores how they reconcile entrepreneurial activities with their social mission. More specifically, we...

Clinical Effectiveness of Budesonide/Formoterol Fumarate Easyhaler® for Patients with Poorly Controlled Obstructive Airway Disease: a Real-World Study of Patient-Reported Outcomes

IntroductionThe effectiveness of inhaled therapies can be influenced by many factors, including the type of inhaler, which may have clinical implications. We report a real-world, multicenter, open-label, non-randomized, non-interventional study conducted by 200 pulmonologists across 200 centers in Hungary. The effectiveness of budesonide/formoterol inhalation therapy in daily...

A review of coastal management approaches to support the integration of ecological and human community planning for climate change

The resilience of socio-ecological systems to sea level rise, storms and flooding can be enhanced when coastal habitats are used as natural infrastructure. Grey infrastructure has long been used for coastal flood protection but can lead to unintended negative impacts. Natural infrastructure often provides similar services as well as added benefits that support short- and long...

Incidencia De Los Aspectos Psicosociales En La Deserción De Los Estudiantes Universitarios

This paper focuses on determining the incidence of the psychosocial aspects of the dropout of students from the School of Marketing at the School of Business Administration of the Higher Polytechnic School in Chimborazo. In this study, the dependent variable include Psychological, Socioeconomic aspects, and its environment. In the dependent variable, the problems of the students...

Impact of Arctic sea ice variations on winter temperature anomalies in northern hemispheric land areas

Coordinated numerical ensemble experiments with six different state-of-the-art atmosphere models have been used in order to evaluate the respective impact of the observed Arctic sea ice and sea surface temperature (SST) variations on air temperature variations in mid and high latitude land areas. Two sets of experiments have been designed; in the first set (EXP1), observed daily...

Probing Spintronic Features in Conduction through Silicene and Graphene Barriers

The Dirac electrons in silicene experience stronger spin-orbit interaction (SOI) than in graphene due to silicene's band buckled two-dimensional (2D) structure. In this work we theoretically probe the main effects of the SOI in silicene, provided this interaction can be controlled by an external electrical field. Attention is paid to how silicene's SOI effects can turn into...