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Preparation of arginine–glycine–aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization

Che-Yi Chang,1,2,* Ming-Chen Wang,2,* Takuya Miyagawa,1 Zhi-Yu Chen,1 Feng-Huei Lin,3,4 Ko-Hua Chen,5,6 Guei-Sheung Liu,7 Ching-Li Tseng1 1Graduate Institute of Biomedical Materials and Tissue

Risk alleles for IgA nephropathy-associated SNPs conferred completely opposite effects to idiopathic membranous nephropathy in Chinese Han

were found to be significantly associated with the susceptibility of IMN, with rs9275596 as the top one (p = 1.97E-43, Xiaosong Qin and Chen Wang contributed equally to the work. - Department of

The impacts of network competence, knowledge sharing on service innovation performance: Moderating role of relationship quality

Zhaoquan Jian 0 Chen Wang 0 0 School of Business Administration, South China University of Technology (China) Purpose: To examine how network competence, knowledge sharing and relationship quality affect

The optimum timing to wean invasive ventilation for patients with AECOPD or COPD with pulmonary infection

The optimum timing to wean invasive ventilation for patients with AECOPD or COPD with pulmonary infection Yuanlin Song,1 Rongchang Chen,2 Qingyuan Zhan,3 Shujing Chen,1 Zujin Luo,4 Jiaxian Ou,1 Chen Wang3 1Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, Shanghai, 2Guangzhou Institute of Respiratory Disease, Guangzhou, 3Department of Respiratory and...

Comparative analysis of volatiles difference of Yunnan sun-dried Pu-erh green tea from different tea mountains: Jingmai and Wuliang mountain by chemical fingerprint similarity combined with principal component analysis and cluster analysis

Background Modern instrumental analysis technology can provide various chemical data and information on tea samples. Unfortunately, it remains difficult to extract the useful information. We describe the use of chemical fingerprint similarities, combined with principal component and cluster analyses, to distinguish and recognize Pu-erh green teas, which from two tea mountains...

Cloning and molecular identification of triosephosphate isomerase gene from Apis cerana cerana and its role in response to various stresses

Apis cerana cerana triosephosphate isomerase (AccTPI), a key regulatory enzyme in glycolysis and gluconeogenesis pathway, catalyzes the interconversion of glyceraldehyde 3-phosphate to dihydroxyacetone phosphate. However, its role in A. cerana cerana has not been completely clarified. In this study, a TPI gene was cloned from A. cerana cerana and named AccTPI. The open reading...

Differentiating Ideals versus Practices in the Discussion of Confucian Influences on Chinese Parent–Child Relationships

The primary purpose of this essay is to call for a renewed understanding of Confucianism in the discussion of Chinese parent-child relationships. Citing historical evidence, we present the evolution of Confucianism as a school of thought in China. In addition, we present research on Chinese parent–child relationships, which to a varying degree are said to be associated with...

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis Promotes Hepatic Stellate Cells Migration via Canonical NF-κB/MMP9 Pathway

In the liver, the signal and function of tumor necrosis factor-like weak inducer of apoptosis (TWEAK) have mainly been assessed in association with liver regeneration. However, the effects of TWEAK on liver fibrosis have not been fully elucidated. To investigate the effects of TWEAK on human hepatic stellate cells (HSCs) and to explore the relevant potential mechanisms, human...

The Predictive Effects of Early Pregnancy Lipid Profiles and Fasting Glucose on the Risk of Gestational Diabetes Mellitus Stratified by Body Mass Index

, China Received 9 November 2015; Accepted 13 January 2016 Academic Editor: Andrea Tura Copyright © 2016 Chen Wang et al. This is an open access article distributed under the Creative Commons ... . Conflict of Interests The authors have declared no conflict of interests. Authors’ Contribution Chen Wang was involved in the collection and analysis of the data as well as drafting of the paper. Weiwei Zhu

Extra-Nuclear Signaling Pathway Involved in Progesterone-Induced Up-Regulations of p21cip1 and p27kip1 in Male Rat Aortic Smooth Muscle Cells

Previously, we demonstrated that progesterone (P4) at physiologic levels (5-500 nM) inhibited proliferation in cultured rat aortic smooth muscle cells (RASMCs) through a P4 receptor (PR)-dependent pathway. We also showed that P4-induced cell cycle arrest in RASMCs occurs when the cyclin-CDK2 system is inhibited just as p21cip1 and p27kip1 protein levels are augmented. In the...

Alteration in Expression and Methylation of IGF2/H19 in Placenta and Umbilical Cord Blood Are Associated with Macrosomia Exposed to Intrauterine Hyperglycemia

Objective Macrosomia is one of the most common complications in gestational diabetes mellitus. Insulin-like growth factor 2 and H19 are two of the imprinted candidate genes that are involved in fetal growth and development. Change in methylation at differentially methylated region of the insulin-like growth factor 2 and H19 has been proved to be an early event related to the...

Identification of lncRNA FAM83H-AS1 as a novel prognostic marker in luminal subtype breast cancer

, Ou-Chen Wang Department of Surgical Oncology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China Background: Luminal subtype breast cancer

Enhanced performance of solar cells via anchoring CuGaS2 quantum dots

Ternary I–III–VI quantum dots (QDs) of chalcopyrite semiconductors exhibit excellent optical properties in solar cells. In this study, ternary chalcopyrite CuGaS2 nanocrystals (2–5 nm) were one-pot anchored on TiO2 nanoparticles (TiO2@CGS) without any long ligand. The solar cell with TiO2@CuGaS2/N719 has a power conversion efficiency of 7.4%, which is 23% higher than that of...

Patterns and Structures of Land Use Change in the Three Rivers Headwaters Region of China

Located in Qinghai Province of China, the Three Rivers Headwaters Region is the source region of the Yangtze, Yellow and Lantsang Rivers, and plays an important role in biodiversity conservation and regulating water supply. Despite many efforts on land use change in Qinghai, knowledge of the spatial variation of land use change is still lacking. This study examines the patterns...

Asthma, corticosteroid use and schizophrenia: A nationwide population-based study in Taiwan

Objective Asthma and corticosteroid use have been implicated as possible risk factors for schizophrenia. The retrospective cohort study herein aimed to investigate the association between asthma, corticosteroid use, and schizophrenia. Method Longitudinal data (2000 to 2007) from adults with asthma (n = 50,046) and without asthma (n = 50,046) were compared on measures of...

The Chondrogenic Induction Potential for Bone Marrow-Derived Stem Cells between Autologous Platelet-Rich Plasma and Common Chondrogenic Induction Agents: A Preliminary Comparative Study

The interests in platelet-rich plasma (PRP) and their application in stem cell therapy have contributed to a better understanding of the basic biology of the prochondrogenesis effect on bone marrow-derived stem cells (BMSCs). We aimed at comparing the effect of autologous PRP with common chondrogenic induction agents (CCIAs) on the chondrogenic differentiation of BMSCs. Rabbit...

A Geo-Aware Taxi Carrying Management System by Using Location Based Services and Zone Queuing Techniques on Internet of Things

Taxi plays a crucial role in the transportation system because of the characteristic that can be hailed conveniently. Most of the taxi drivers obtain passengers by hunting on the road or waiting in a fixed taxi queuing point; however these methods have poor performance, high vacancy rate, and several critical problems such as air pollution and foul up traffic. This study proposed...

Human Adipocytes Stimulate Invasion of Breast Cancer MCF-7 Cells by Secreting IGFBP-2

Background and Aims A better understanding of the effects of human adipocytes on breast cancer cells may lead to the development of new treatment strategies. We explored the effects of adipocytes on the migration and invasion of breast cancer cells both in vitro and in vivo. Methods To study the reciprocal effects of adipocytes and cancer cells, we co-cultured human mature...

A comparison of beliefs about exercise during pregnancy between Chinese and Australian pregnant women

Science , Exercise and Health , The University of Western Australia , 35 Stirling Highway, Crawley, Western Australia 6009 , Australia 2 Kym J. Guelfi and Chen Wang are co-first authors 3 School of Women's

NanoString-based breast cancer risk prediction for women with sclerosing adenosis

Purpose Sclerosing adenosis (SA), found in ¼ of benign breast disease (BBD) biopsies, is a histological feature characterized by lobulocentric proliferation of acini and stromal fibrosis and confers a two-fold increase in breast cancer risk compared to women in the general population. We evaluated a NanoString-based gene expression assay to model breast cancer risk using RNA...