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REG3A promotes the proliferation, migration, and invasion of gastric cancer cells

REG3A promotes the proliferation, migration, and invasion of gastric cancer cells Zhou-Feng Chen, Zhi-Ming Huang, Hai-Bo Xue, Xiu-Qing Lin, Ren-Ping Chen, Meng-Jun Chen, Rui-Fang Jin Department of

Warming up human body by nanoporous metallized polyethylene textile

, Yucan Peng, Jun Chen, Chong Liu, Yayuan Liu, Ankun Yang, Chenxing Zhou, Chenyu Zhou & Yi CuiE.L. Ginzton Laboratory, Department of Electrical Engineering, Stanford University, Stanford, CA, 94305, USAAlex ... • PubMed • Google Scholar Search for Po-Chun Hsu in:Nature Research journals • PubMed • Google Scholar Search for Yucan Peng in:Nature Research journals • PubMed • Google Scholar Search for Jun Chen

Dropping Impact Characteristics Analysis of a Cubic Nonlinear Packaging System with a Cantilever Beam Type Elastic Critical Component with Concentrated Tip Mass

; Accepted 20 October 2014 Academic Editor: Jun Wang Copyright © 2015 Meng Hao and An-Jun Chen. This is an open access article distributed under the Creative Commons Attribution License, which permits

Temperature-Related Reaction Norms of Gene Expression: Regulatory Architecture and Functional Implications

The environment has profound effects on the expression of many traits and reaction norms describe the expression dynamics of a trait across a broad range of environmental conditions. Here, we analyze gene expression in Drosophila melanogaster across four different developmental temperatures (13–29 °C). Gene expression is highly plastic with 83.3% of the genes being differentially...

Long Noncoding RNA MIR4697HG Promotes Cell Growth and Metastasis in Human Ovarian Cancer

Ovarian cancer is one of the three most common gynecological malignant tumors worldwide. The prognosis of patients suffering from this malignancy remains poor because of limited therapeutic strategies. Herein, we investigated the role of a long noncoding RNA named MIR4697 host gene (MIR4697HG) in the cell growth and metastasis of ovarian cancer. Results showed that the...

Grassy Silica Nanoribbons and Strong Blue Luminescence

Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044, JapanYujin Cho & Jun Chen AuthorsSearch for Shengping Wang in:Nature Research journals • PubMed • Google ScholarSearch for Shuang ... • Google ScholarSearch for Yujin Cho in:Nature Research journals • PubMed • Google ScholarSearch for Jun Chen in:Nature Research journals • PubMed • Google ScholarSearch for Daisuke Fujita in:Nature Research

Functional Nanomaterials for Sustainable Energy Technologies

University, Chongqing 400044, China 4Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139, USA Received 12 April 2016; Accepted 13 April 2016 Copyright © 2016 Jun Chen et al ... works presented in this special issue will render the readers useful information and facilitate the further development of the research field. Jun Chen Guang Zhu Weiqing Yang Jin Yang Long Lin Yaqing Bie

Identification of a Potential Target of Capsaicin by Computational Target Fishing

Capsaicin, the component responsible for the pungency of chili peppers, shows beneficial effects in many diseases, although the underlying mechanisms remain unclear. In the present study, the potential targets of capsaicin were predicted using PharmMapper and confirmed via chemical-protein interactome (CPI) and molecular docking. Carbonic anhydrase 2 was identified as the main...

Vibration Analysis of Suspension Cable with Attached Masses by Non-linear Spline Function Method

The nonlinear strain and stress expressions of suspension cable are established from the basic condition of suspension structure on the Lagrange coordinates and the equilibrium equation of the suspension structure is obtained. The dynamics equations of motion of the suspended cable with attached masses are proposed according to the virtual work principle. Using the spline...

Exploration of inhibitory mechanisms of curcumin in lung cancer metastasis using a miRNA- transcription factor-target gene network

The present study was aimed to unravel the inhibitory mechanisms of curcumin for lung cancer metastasis via constructing a miRNA-transcription factor (TF)-target gene network. Differentially expressed miRNAs between human high-metastatic non-small cell lung cancer 95D cells treated with and without curcumin were identified using a TaqMan human miRNA array followed by real-time...

TRPA1 as a drug target—promise and challenges

Jun Chen 0 David H. Hackos 0 0 D. H. Hackos Department of Neuroscience, Genentech , South San Francisco, CA 94080 , USA 1 ) Department of Biochemical and Cellular Pharmacology, Genentech , South

PET/CT-guided percutaneous biopsy of FDG-avid metastatic bone lesions in patients with advanced lung cancer: a safe and effective technique

Purpose 18F-FDG PET/CT should be performed before a diagnostic biopsy site is chosen in patients with a high clinical suspicion of aggressive, advanced tumour. The aim of this study was to evaluate the safety and efficacy of 18F-FDG PET/CT in guiding biopsy of bone metastases in patients with advanced lung cancer. Methods PET/CT-guided percutaneous core biopsies were performed in...

Synthesis and Cytotoxicity Evaluation of Tropinone Derivatives

-Jun Chen 0 1 2 0 C.-A. Geng T.-H. Yang T.-Z. Li X.-M. Zhang J.-J. Chen Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201

Local and distant trauma after hypervelocity ballistic impact to the pig hind limb

The development of high-energy weapons could increase the velocity of projectiles to well over 1000 m/s. The nature of the injuries caused by the ballistic impact of projectiles at velocities much faster than 1000 m/s is unclear. This study characterizes the mechanical and biochemical alterations caused by high-speed ballistic impact generated by spherical steel ball to the hind...

Serological Response Predicts Normalization of Cerebrospinal Fluid Abnormalities at Six Months after Treatment in HIV-Negative Neurosyphilis Patients

Province, ChinaYao Xiao, Man-Li Tong, Li-Rong Lin, Li-Li Liu, Kun Gao, Mei-Jun Chen, Hui-Lin Zhang, Wei-Hong Zheng, Tian-Ci Yang & Jian-Jun NiuXiamen Hospital of Traditional Chinese Medicine, Xiamen, Fujian ... Mei-Jun Chen in:Nature Research journals • PubMed • Google Scholar Search for Hui-Lin Zhang in:Nature Research journals • PubMed • Google Scholar Search for Wei-Hong Zheng in:Nature Research journals

Machine Learning Classification of Cirrhotic Patients with and without Minimal Hepatic Encephalopathy Based on Regional Homogeneity of Intrinsic Brain Activity

Machine learning-based approaches play an important role in examining functional magnetic resonance imaging (fMRI) data in a multivariate manner and extracting features predictive of group membership. This study was performed to assess the potential for measuring brain intrinsic activity to identify minimal hepatic encephalopathy (MHE) in cirrhotic patients, using the support...

Temperature Stress Mediates Decanalization and Dominance of Gene Expression in Drosophila melanogaster

The regulatory architecture of gene expression remains an area of active research. Here, we studied how the interplay of genetic and environmental variation affects gene expression by exposing Drosophila melanogaster strains to four different developmental temperatures. At 18°C we observed almost complete canalization with only very few allelic effects on gene expression. In...

Molybdenum Nanoscrews: A Novel Non-coinage-Metal Substrate for Surface-Enhanced Raman Scattering

For the first time, Mo nanoscrew was cultivated as a novel non-coinage-metal substrate for surface-enhanced Raman scattering (SERS). It was found that the nanoscrew is composed of many small screw threads stacking along its length direction with small separations. Under external light excitation, strong electromagnetic coupling was initiated within the gaps, and many hot-spots...