Advanced search    

Search: authors:"Jun Chen"

333 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study

Li 0 Heng Li Qian Liang Jun Chen Jianghua Chen 0 Equal contributors Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University , 79 Qingchun Road, Hangzhou 310003

Changes in enterovirus serotype constituent ratios altered the clinical features of infected children in Guangdong Province, China, from 2010 to 2013

Background Enterovirus (EV)-related hand, foot, and mouth disease/herpangina (HFMD/HA) has been prevalent in Guangdong Province, China, since 2010. Methods Clinical data for EV-related HFMD/HA inpatients admitted to the Department of Paediatrics of Zhujiang Hospital from 2010 to 2013 were retrospectively reviewed. The corresponding EV serotypes were also determined by reverse...

Potential contribution of the uterine microbiome in the development of endometrial cancer

Background Endometrial cancer studies have led to a number of well-defined but mechanistically unconnected genetic and environmental risk factors. One of the emerging modulators between environmental triggers and genetic expression is the microbiome. We set out to inquire about the composition of the uterine microbiome and its putative role in endometrial cancer. Methods We...

Protocol of a prospective study for the combination treatment of Shu-Gan-jian-Pi decoction and steroid standard therapy in autoimmune hepatitis patients

Background Prednisone plus azathioprine is considered the mainstay of therapy in the current recommendations for autoimmune hepatitis (AIH). However, it does not provide good benefits for AIH patients because of its serious side effects. Therefore, more and more AIH patients prefer to seek for traditional Chinese medicine (TCM) to manage their symptoms and reduce the side effects...

Lung ultrasonography for the diagnosis of 11 patients with acute respiratory distress syndrome due to bird flu H7N9 infection

Ying Zhan Jun Chen 0 Equal contributors Intensive Care Unit of the Department of Anesthesiology, The First Hospital Affiliated to Suzhou University , Suzhou 215006, Jiangsu , China Background: A novel ... where H7N9 infection is emergent in humans. Authors’ contributions Yu-kun Zhang, Jian Li, and Jun Chen designed the study and co-wrote the manuscript. Yu-kun Zhang, Jian Li, Jian-ping Yang, and Ying Zhan

An expansion of rare lineage intestinal microbes characterizes rheumatoid arthritis

Background The adaptive immune response in rheumatoid arthritis (RA) is influenced by an interaction between host genetics and environment, particularly the host microbiome. Association of the gut microbiota with various diseases has been reported, though the specific components of the microbiota that affect the host response leading to disease remain unknown. However, there is...

Distinguishing Patients with Parkinson's Disease Subtypes from Normal Controls Based on Functional Network Regional Efficiencies

Many studies have demonstrated that the pathophysiology and clinical symptoms of Parkinson's disease (PD) are inhomogeneous. However, the symptom-specific intrinsic neural activities underlying the PD subtypes are still not well understood. Here, 15 tremor-dominant PD patients, 10 non-tremor-dominant PD patients, and 20 matched normal controls (NCs) were recruited and underwent...

The Incidence, Clinical Outcomes, and Risk Factors of Thrombocytopenia in Intra-Abdominal Infection Patients: A Retrospective Cohort Study

Background Studies on the incidence and risk factors of thrombocytopenia among intra-abdominal infection patients remain absent, hindering efficacy assessments regarding thrombocytopenia prevention strategies. Methods We retrospectively studied 267 consecutively enrolled patients with intra-abdominal infections. Occurrence of thrombocytopenia was scanned for all patients. All...

Exploring the Intrinsic Piezofluorochromic Mechanism of TPE-An by STS Technique

9,10-bis(4-(1,2,2-triphenylvinyl)styryl)anthracene (TPE-An) materials have attracted considerable attention in recent years because they have high luminescence efficiency and excellent piezofluorochromic properties, which have potential applications in organic light-emitting display (OLED) area. Scanning tunneling spectroscopy (STS) technique was used to study the...

Inorganic & organic materials for rechargeable Li batteries with multi-electron reaction

Advanced Energy Materials Chemistry (Ministry of Education) to study for his PhD degree. He is expecting to get his PhD in 2015 under the supervision of Professor Jun Chen. His research focuses on Liion ... batteries, Li-S batteries, and Na-ion batteries. Jun Chen was born in 1967. He is a Cheung Kong Scholar Professor at the College of Chemistry, Nankai University, and Vice Chairman of the Chinese Society of

Distributed indeterminacy evaluation of cable-strut structures: formulations and applications

The indeterminacy evaluation is an effective method for system identification; it can predict the mechanical behaviors of flexible structures in the primary design. However, the conventional indeterminacy evaluation based solely on geometry and topology has neglected the influence of material properties on mechanical behavior and the contribution of each component to the total...

B7H1 Expression and Epithelial-To-Mesenchymal Transition Phenotypes on Colorectal Cancer Stem-Like Cells

Cancer stem cells (CSCs) can invade and metastasize by epithelial-to-mesenchymal transition (EMT). However, how they escape immune surveillance is unclear. B7H1 is crucial negative co-stimulatory molecule but little information about whether it works in CSCs. Therefore, we determined the expression of B7H1 and EMT-associated markers in colorectal cancer stem-like cells to...

Sarcoidosis misdiagnosed as malignant tumors: a case report

Song Xu 1 Jun Chen 1 0 Equal contributors 1 Department of Lung Cancer Surgery, Lung Cancer Institute, Tianjin Medical University General Hospital , No. 154 Anshan Road, Heping District, Tianjin 300052 ... manuscript. Education Ministry (to Song Xu), Tianjin Science and Technology Support Program (12ZCDZSY16100 to Jun Chen), and Tianjin Educational Committee Foundation (20120117 to Song Xu). 1. Colby TV

Computational methods for the zero-stress state and the pre-stress state of tensile cable-net structures

This paper proposes an extended design concept and mechanical description for cable-net structures, including 10 states and 15 procedures which are defined according to their physical nature and analytical capabilities. In the pre-stress release analysis, an iterative computational method is developed for the inverse evaluation from the equilibrium state to the zero-stress state...

Causes, clinical features and outcomes of drug-induced liver injury in hospitalized patients in a Chinese tertiary care hospital

Drug-induced liver injury (DILI) is an important liver disease in China, owing to the country’s huge population and the availability of a multitude of drugs. Consequently, DILI is becoming an increasingly serious health problem. However, there is not enough relevant epidemiological data, and the clinical features of these patients are not clear. We conducted this study to report...

Serial cfDNA assessment of response and resistance to EGFR-TKI for patients with EGFR-L858R mutant lung cancer from a prospective clinical trial

Background Detecting epidermal growth factor receptor (EGFR) activating mutations in plasma could guide EGFR-tyrosine kinase inhibitor (EGFR-TKI) treatment for advanced non-small cell lung cancer (NSCLC). However, dynamic quantitative changes of plasma EGFR mutations during the whole course of EGFR-TKI treatment and its correlation with clinical outcomes were not determined. The...

A Neural Network Model for K(λ) Retrieval and Application to Global Kpar Monitoring

Accurate estimation of diffuse attenuation coefficients in the visible wavelengths Kd(λ) from remotely sensed data is particularly challenging in global oceanic and coastal waters. The objectives of the present study are to evaluate the applicability of a semi-analytical Kd(λ) retrieval model (SAKM) and Jamet’s neural network model (JNNM), and then develop a new neural network Kd...

The association between S100A13 and HMGA1 in the modulation of thyroid cancer proliferation and invasion

Background S100A13 and high mobility group A (HMGA1) are known to play essential roles in the carcinogenesis and progression of cancer. However, the correlation between S100A13 and HMGA1 during cancer progression is not yet well understood. In this study, we determined the effects of S100A13 on HMGA1 expression in thyroid cancer cells and examined the role of HMGA1 in thyroid...