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Size effect of Au/PAMAM contrast agent on CT imaging of reticuloendothelial system and tumor tissue

Polyamidoamine (PAMAM)-entrapped Au nanoparticles were synthesized with distinct sizes to figure out the size effect of Au-based contrast agent on CT imaging of passively targeted tissues. Au/PAMAM nanoparticles were first synthesized with narrow distribution of particles size of 22.2 ± 3.1, 54.2 ± 3.7, and 104.9 ± 4.7 nm in diameters. Size effect leads no significant difference on ...

Production of \(a_1\) in heavy meson decays

Eur. Phys. J. C Production of a1 in heavy meson decays Wei Wang 0 1 Zhen-Xing Zhao 1 0 State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences

Dysregulation of endothelial colony-forming cell function by a negative feedback loop of circulating miR-146a and -146b in cardiovascular disease patients

CAD ECFCs (RPM > 5 and > 3-fold change). (TIF) Acknowledgments This paper is dedicated to the memory of Dr. Hsei-Wei Wang, April 1969~Sep 2015. We thank Dr. Pei-Ching Chang (National Yang-Ming ... : Ting-Yu Chang, Shu-Meng Cheng, Hsei-Wei Wang. Data curation: Ting-Yu Chang, Tse-Shun Huang. Formal analysis: Ting-Yu Chang, Tse-Shun Huang. Funding acquisition: Wei-Chi Tsai, Chun-Hsien Wu, Cheng

Dexmedetomidine sedation reduces atrial fibrillation after cardiac surgery compared to propofol: a randomized controlled trial

Background Atrial fibrillation occurs frequently in patients following cardiac surgery and can be a cause of increased morbidity and mortality. The use of dexmedetomidine to prevent atrial fibrillation is unclear. The present study was designed to evaluate the effect of dexmedetomidine sedation on the incidence of atrial fibrillation after cardiac surgery. Methods Upon arrival to ...

Comparison of Two Cap Thickness in Small Incision Lenticule Extraction: 100μm versus 160μm

Purpose To compare the changes of biomechanical properties, endothelial cell density (ECD), and posterior corneal elevation (PCE) after femtosecond small incision lenticule extractions (SMILEs) with 100μm versus 160μm cap thicknesses. Methods A total of 12 rabbits were randomly assigned into two groups of 6 each. SMILE was performed at a depth of either 160μm (160-cap group) or ...

Hepatocyte nuclear factor 1α downregulates HBV gene expression and replication by activating the NF-κB signaling pathway

The role of hepatocyte nuclear factor 1α (HNF1α) in the regulation of gene expression and replication of hepatitis B virus (HBV) is not fully understood. Previous reports have documented the induction of the expression of viral large surface protein (LHBs) by HNF1α through activating viral Sp1 promoter. Large amount of LHBs can block the secretion of hepatitis B surface antigen ...

Comparison of Delta-Shape Anastomosis and Extracorporeal Billroth I Anastomosis after Laparoscopic Distal Gastrectomy for Gastric Cancer: A Systematic Review with Meta-Analysis of Short-Term Outcomes

Objective The aim of this systematic review and meta-analysis is to evaluate the safety and relative benefits of delta-shape anastomosis (DA) by comparing to conventional laparoscopy-assisted distal gastrectomy with Billroth I gastroduodenostomy (LADG BI). Methods Studies and relevant literature regarding DA versus LADG BI were searched in the electronic databases. Operation time, ...

Model updating mechanism of concept drift detection in data stream based on classifier pool

In data stream, concept drift often occurs in an unpredictable way, the classifier model which was learned from previous data is not accurate to the current data, so regular updating of the model is necessary. Moreover, updating too frequently will cause a negative impact on the clustering accuracy and the analysis of subsequent data. This paper proposed a model-updating mechanism ...

Safety and tolerability of high-dose ulinastatin after 2-hour intravenous infusion in adult healthy Chinese volunteers: A randomized, double-blind, placebo-controlled, ascending-dose study

Ulinastatin, is a broad-spectrum protease inhibitor purified from human urine, inhibits endogenous proteases such as trypsin, α-chymotrypsin, hyaluronidase, and plasmin. It is widely being used at increasingly higher doses for the treatment of acute or chronic pancreatitis, severe infection, and acute organ failure. We aimed to evaluate the safety and tolerability of high-dose ...

Porous yet dense metal-free electro-materials for compact energy storage

Metal-free electro-materials, made of mainly conjugated carbon atoms as well as other elements, allow the development of abundant porosity and good conductivity. Most importantly, metal-free electro-materials are preferential in terms of sustainability, chemical variety and processability. Nevertheless the challenge of using metal-free materials is to increase the density. ...

Visual and noxious electrical stimulus-evoked membrane-potential responses in anterior cingulate cortical neurons

Wang 2 3 0 Equal contributors 1 Institute and Key Laboratory of Brain Functional Genomics of Shanghai and Chinese Ministry of Education, Shanghai Key Laboratory of Brain Functional Genomics, School of

Cytokinin-Regulated Sucrose Metabolism in Stay-Green Wheat Phenotype

A wheat stay-green mutant, tasg1, was observed to exhibit significantly delayed senescence in the late developmental stage. The photosynthetic capacity of the flag leaf was greater in tasg1 than in wild type (WT) plants. In addition, the grain volume of tasg1 was significantly higher than that of WT at the early filling stage. The content of various cytokinins (CKs) in the grain ...

Genetic engineering of Pseudomonas chlororaphis GP72 for the enhanced production of 2-Hydroxyphenazine

Background The biocontrol strain Pseudomonas chlororaphis GP72 isolated from the green pepper rhizosphere synthesizes three antifungal phenazine compounds, 2-Hydroxyphenazine (2-OH-PHZ), 2-hydroxy-phenazine-1-carboxylic acid (2-OH-PCA) and phenazine-1-carboxylic acid (PCA). PCA has been a commercialized antifungal pesticide registered as “Shenqinmycin” in China since 2011. It is ...

Analysis of the Negative-SET Behaviors in Cu/ZrO2/Pt Devices

Metal oxide-based electrochemical metallization memory (ECM) shows promising performance for next generation non-volatile memory. The negative-SET behavior has been observed in various oxide-based ECM devices. But the underlying mechanism of this behavior remains unaddressed and the role of the metal cation and oxygen vacancy in this behavior is unclear. In this work, we have ...

Analysis of the Negative-SET Behaviors in Cu/ZrO2/Pt Devices

Metal oxide-based electrochemical metallization memory (ECM) shows promising performance for next generation non-volatile memory. The negative-SET behavior has been observed in various oxide-based ECM devices. But the underlying mechanism of this behavior remains unaddressed and the role of the metal cation and oxygen vacancy in this behavior is unclear. In this work, we have ...

Bibliographic Analysis of Nature Based on Twitter and Facebook Altmetrics Data

This paper presents a bibliographic analysis of Nature articles based on altmetrics. We assess the concern degree of social users on the Nature articles through the coverage analysis of Twitter and Facebook by publication year and discipline. The social media impact of a Nature article is examined by evaluating the mention rates on Twitter and on Facebook. Moreover, the correlation ...

Challenges for strengthening the health workforce in the Lao People’s Democratic Republic: perspectives from key stakeholders

Background The Lao People’s Democratic Republic is facing a critical shortage and maldistribution of health workers. Strengthening of the health workforce has been adopted as one of the five priorities of the National Health Sector Strategy (2013–2025). This study aims to identify, explore, and better understand the key challenges for strengthening the Laotian health workforce. ...

Increased expression of TROP2 in airway basal cells potentially contributes to airway remodeling in chronic obstructive pulmonary disease

Background The airway epithelium of chronic obstructive pulmonary disease (COPD) patients undergoes aberrant repair and remodeling after repetitive injury following exposure to environmental factors. Abnormal airway regeneration observed in COPD is thought to originate in the stem/progenitor cells of the airway epithelium, the basal cells (BCs). However, the molecular mechanisms ...

Improving the thermostability and stress tolerance of an archaeon hyperthermophilic superoxide dismutase by fusion with a unique N-terminal domain

Wei Wang 0 1 2 0 Key Laboratory of Molecular Microbiology and Technology, Ministry of Education, TEDA Institute of Biological Sciences and Biotechnology, Nankai University , 23 Hongda Street, TEDA