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Factors associated with clinical outcome in 25 patients with avian influenza A (H7N9) infection in Guangzhou, China

Chen Kuibiao Li Hui Liu Lei Luo Ming Wang ZhiCong Yang 0 Equal contributors Guangzhou Centre for Disease Control and Prevention , No. 1, Qide Rd, Jiahe, Baiyun, Guangzhou 510440 , China Background

One-Step Synthesis of Spherical γ-Fe2O3 Nanopowders and the Evaluation of Their Photocatalytic Activity for Orange I Degradation

Maghemite (γ-Fe2O3) nanopowders were synthesized under aeration (oxidizing) conditions by aqueous synthesis in this study. The microstructures of the prepared powders were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and BET-BJH. The XRD analysis and the chemical experiments showed that well-crystallized γ-Fe2O3 nanoparticles were successfully...

One-Step Synthesis of Spherical γ-Fe2O3 Nanopowders and the Evaluation of Their Photocatalytic Activity for Orange I Degradation

Maghemite (γ-Fe2O3) nanopowders were synthesized under aeration (oxidizing) conditions by aqueous synthesis in this study. The microstructures of the prepared powders were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), and BET-BJH. The XRD analysis and the chemical experiments showed that well-crystallized γ-Fe2O3 nanoparticles were successfully...

Role of SIRT3 in Angiotensin II-induced human umbilical vein endothelial cells dysfunction

Background SIRT3, a member of the sirtuin family of NAD + -dependent deacetylases, resides primarily in the mitochondria and has been shown to deacetylate several metabolic and respiratory enzymes that regulate important mitochondrial functions. Previous researches show an important role of SIRT3 in regulating the production of reactive oxygen species (ROS), and highlight the...

Elevated Levels of Serum Tumor Markers CEA and CA15-3 Are Prognostic Parameters for Different Molecular Subtypes of Breast Cancer

Background & Aims The utility of measuring carcinoembryonic antigen(CEA) and cancer antigen 15-3 (CA15-3) levels in patients with breast cancer remains controversial. The present study aims to investigate the prognostic value of preoperative serum CEA and CA15-3 levels in breast cancer patients. Methods Serum preoperative CEA and CA 15-3 concentration levels were measured in a...

The Mass Loss and Humification of Stumps and Roots in Masson Pine Plantations Based on Log File Records

Stumps account for a large proportion of coarse woody debris in managed forests, but their decay dynamics are poorly understood. The loss of mass and the degree of humification of the above-ground woody debris, below-ground woody debris, bark and root system (R1, 10 mm ≥ diameter > 0 mm; R2, 25 mm ≥ diameter >10 mm; 100 mm ≥ R3 > 25 mm; R4 > 100 mm) of Masson pine (Pinus...

Improving compound–protein interaction prediction by building up highly credible negative samples

Motivation: Computational prediction of compound–protein interactions (CPIs) is of great importance for drug design and development, as genome-scale experimental validation of CPIs is not only time-consuming but also prohibitively expensive. With the availability of an increasing number of validated interactions, the performance of computational prediction approaches is severely...

Primary spontaneous pneumothorax: simultaneous treatment by bilateral non-intubated videothoracoscopy

OBJECTIVES Through a retrospective study, we assessed the feasibility and safety of simultaneous bilateral thoracoscopic wedge resection of blebs or bullae for the treatment of primary spontaneous pneumothorax (PSP) under thoracic epidural anaesthesia with spontaneous ventilation.

Reduced γ-Aminobutyric Acid and Glutamate

 Huiru Cui,1 Lihua Xu,1 Botao Zeng,1 Yu Li,1 Gaiying Li,2 Chunbo Li,1,3 Hui Liu,4 Zheng Lu,5 Jianye Zhang,6 and Jijun Wang1,3 1Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center

Assessment of Vascularity in Hepatic Alveolar Echinococcosis: Comparison of Quantified Dual-Energy CT with Histopathologic Parameters

Purpose To investigate whether dual-energy computer tomography(DECT) could determine the angiographic vascularity of alveolar echinococcosis lesions by comparing the quantitative iodine concentration (IC) with the microvascular density (MVD). Material and Methods Twenty-five patients (16 men, 9 women; mean age, 40.9 ± 13.8 years) with confirmed hepatic alveolar echinococcosis...

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs

Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease with cellular and molecular mechanisms yet to be fully described. Mutations in a number of genes including SOD1 and FUS are associated with familial ALS. Here we report the generation of induced pluripotent stem cells (iPSCs) from fibroblasts of familial ALS patients bearing SOD1 +/A272C and FUS +/G1566A...

Long non-coding RNA AK027294 involves in the process of proliferation, migration, and apoptosis of colorectal cancer cells

This study is aimed to investigate the differentially expressed long non-coding RNAs (lncRNAs) in colorectal cancer and its potential biological function. Colorectal adenoma is the precancerous lesions of colorectal cancer, so in this study, we used colorectal adenoma as negative control. The global lncRNA expression profile in colorectal cancer and adenoma was evaluated by...

Spatiotemporal Variation and Abrupt Change Analysis of Temperature from 1960 to 2012 in the Huang-Huai-Hai Plain, China

Based on a monthly dataset of temperature time series (1960–2012) in the Huang-Huai-Hai Plain of China (HHHPC), spatiotemporal variation and abrupt change analysis of temperature were examined by moving average, linear regression, spline interpolation, Mann-Kendall test, and moving t-test. Major conclusions were listed as follows. (1) Annual and seasonal temperature increased...

More Dialectical Thinking, Less Creativity? The Relationship between Dialectical Thinking Style and Creative Personality: The Case of China

People use dialectical thinking to be holistic, reconcile contradictions, and emphasize changes when processing information and managing problems. Using a questionnaire survey, this study examined the relationship between dialectical thinking and creative personality in the Chinese culture, which encourages a holistic and collective thinking style. Undergraduates majoring in...

Generalized logical model based on network topology to capture the dynamical trends of cellular signaling pathways

Background Cellular responses to extracellular perturbations require signaling pathways to capture and transmit the signals. However, the underlying molecular mechanisms of signal transduction are not yet fully understood, thus detailed and comprehensive models may not be available for all the signaling pathways. In particular, insufficient knowledge of parameters, which is a...

Active control of electromagnetic radiation through an enhanced thermo-optic effect

, National Center of Microstructures and Quantum Manipulation, Nanjing University, Nanjing 210093, ChinaChong Sheng, Hui Liu & Shining ZhuCenter for Applied Physics Studies, Louisiana Tech University, Ruston ... , Louisiana 71270, USADentcho A. Genov AuthorsSearch for Chong Sheng in:Nature Research journals • PubMed • Google ScholarSearch for Hui Liu in:Nature Research journals • PubMed • Google ScholarSearch for

Histone modifications involved in cassette exon inclusions: a quantitative and interpretable analysis

Background Chromatin structure and epigenetic modifications have been shown to involve in the co-transcriptional splicing of RNA precursors. In particular, some studies have suggested that some types of histone modifications (HMs) may participate in the alternative splicing and function as exon marks. However, most existing studies pay attention to the qualitative relationship...

Charge Variants of an Avastin Biosimilar Isolation, Characterization, In Vitro Properties and Pharmacokinetics in Rat

Zhao and Wan-Hui Liu are employed by Luye Pharma Group Ltd. Luye Pharma Group Ltd provided support in the form of salaries for authors, but did not have any additional role in the study design, data ... of post-translational Competing Interests: The authors have the following interests: Authors Yan-Yan Zhao, Wan-Hui Liu, Wen-Jie Tao, Li-Li Liu and Zhen-Duo Shen are employed by Luye Pharma Group Ltd