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Prediction of microstructural evolution during hot forging

Microstructural evolution, which is governed by temperature, strain and strain rate during hot forging, is a key factor influencing mechanical properties. Understanding the microstructural evolution of metals and alloys in hot forging has a great importance for the designers of metal forming processes. The principal objective of this paper is to provide an overview of the models...

Dendritic-Tumor Fusion Cells Derived Heat Shock Protein70-Peptide Complex Has Enhanced Immunogenicity

Tumor-derived heat shock protein70-peptide complexes (HSP70.PC-Tu) have shown great promise in tumor immunotherapy due to numerous advantages. However, large-scale phase III clinical trials showed that the limited immunogenicity remained to be enhanced. In previous research, we demonstrated that heat shock protein 70-peptide complexes (HSP70.PC-Fc) derived from dendritic cell (DC...

Circulating Tumor DNA Mutation Profiling by Targeted Next Generation Sequencing Provides Guidance for Personalized Treatments in Multiple Cancer Types

• PubMed • Google Scholar Search for Liangjun Zhu in:Nature Research journals • PubMed • Google Scholar Search for Chunrong Zhu in:Nature Research journals • PubMed • Google Scholar Search for Jun Chen

Investigation on Dynamic Recrystallization Behavior of Martensitic Stainless Steel

The hot deformation behavior of X20Cr13 martensitic stainless steel was studied using the hot compression flow curves corresponding to the temperature range of 900–1150°C under strain rates from 0.01 to 10 s−1. A new mathematical model to estimate the flow stress under hot deformation conditions up to the peak of the flow curves was developed. The critical strains for initiation...

Differential gene expression in patients with subsyndromal symptomatic depression and major depressive disorder

Background Subsyndromal symptomatic depression (SSD) is a subtype of subthreshold depressive and can lead to significant psychosocial functional impairment. Although the pathogenesis of major depressive disorder (MDD) and SSD still remains poorly understood, a set of studies have found that many same genetic factors play important roles in the etiology of these two disorders...

The epidemic characteristics of short stature in school students

, participated in data analysis, drafted the manuscript and participated in its design and coordination. Yue Liu and Xian-jun Chen participated in the design of the study and performed the data acquisition. Li-qi

Altered gut microbiota in female mice with persistent low body weights following removal of post-weaning chronic dietary restriction

Background Nutritional interventions often fail to prevent growth failure in childhood and adolescent malnutrition and the mechanisms remain unclear. Recent studies revealed altered microbiota in malnourished children and anorexia nervosa. To facilitate mechanistic studies under physiologically relevant conditions, we established a mouse model of growth failure following chronic...

Effect of Acarbose on Long-Term Prognosis in Acute Coronary Syndromes Patients with Newly Diagnosed Impaired Glucose Tolerance

Objective. To investigate the effect of acarbose therapy on the long-term prognosis of patients with acute coronary syndromes (ACS) complicating newly diagnosed impaired glucose tolerance (IGT). Methodology. 135 patients hospitalized for ACS who had been newly diagnosed with IGT were randomly assigned to acarbose group (150 mg/day, ) or control group (no acarbose, ). All cases in...

Comparison of tripterygium wilfordii multiglycosides and tacrolimus in the treatment of idiopathic membranous nephropathy: a prospective cohort study

Li 0 Heng Li Qian Liang Jun Chen Jianghua Chen 0 Equal contributors Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University , 79 Qingchun Road, Hangzhou 310003

Complete Inverse Method Using Ant Colony Optimization Algorithm for Structural Parameters and Excitation Identification from Output Only Measurements

Copyright © 2014 Jun Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ... publication of this paper. Acknowledgment Professor Jun Chen gratefully acknowledges financial support for the research represented by this paper, which came from The Project of National Key Technology R&D

Complete Inverse Method Using Ant Colony Optimization Algorithm for Structural Parameters and Excitation Identification from Output Only Measurements

Copyright © 2014 Jun Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ... publication of this paper. Acknowledgment Professor Jun Chen gratefully acknowledges financial support for the research represented by this paper, which came from The Project of National Key Technology R&D

Distinguishing Patients with Parkinson's Disease Subtypes from Normal Controls Based on Functional Network Regional Efficiencies

Many studies have demonstrated that the pathophysiology and clinical symptoms of Parkinson's disease (PD) are inhomogeneous. However, the symptom-specific intrinsic neural activities underlying the PD subtypes are still not well understood. Here, 15 tremor-dominant PD patients, 10 non-tremor-dominant PD patients, and 20 matched normal controls (NCs) were recruited and underwent...

Lung ultrasonography for the diagnosis of 11 patients with acute respiratory distress syndrome due to bird flu H7N9 infection

Ying Zhan Jun Chen 0 Equal contributors Intensive Care Unit of the Department of Anesthesiology, The First Hospital Affiliated to Suzhou University , Suzhou 215006, Jiangsu , China Background: A novel ... where H7N9 infection is emergent in humans. Authors’ contributions Yu-kun Zhang, Jian Li, and Jun Chen designed the study and co-wrote the manuscript. Yu-kun Zhang, Jian Li, Jian-ping Yang, and Ying Zhan

Inorganic & organic materials for rechargeable Li batteries with multi-electron reaction

Advanced Energy Materials Chemistry (Ministry of Education) to study for his PhD degree. He is expecting to get his PhD in 2015 under the supervision of Professor Jun Chen. His research focuses on Liion ... batteries, Li-S batteries, and Na-ion batteries. Jun Chen was born in 1967. He is a Cheung Kong Scholar Professor at the College of Chemistry, Nankai University, and Vice Chairman of the Chinese Society of

Changes in enterovirus serotype constituent ratios altered the clinical features of infected children in Guangdong Province, China, from 2010 to 2013

Background Enterovirus (EV)-related hand, foot, and mouth disease/herpangina (HFMD/HA) has been prevalent in Guangdong Province, China, since 2010. Methods Clinical data for EV-related HFMD/HA inpatients admitted to the Department of Paediatrics of Zhujiang Hospital from 2010 to 2013 were retrospectively reviewed. The corresponding EV serotypes were also determined by reverse...

Prediction of microstructural evolution during hot forging

Microstructural evolution, which is governed by temperature, strain and strain rate during hot forging, is a key factor influencing mechanical properties. Understanding the microstructural evolution of metals and alloys in hot forging has a great importance for the designers of metal forming processes. The principal objective of this paper is to provide an overview of the models...

Liposomal curcumin inhibits hypoxia-induced angiogenesis after transcatheter arterial embolization in VX2 rabbit liver tumors

Liposomal curcumin inhibits hypoxia-induced angiogenesis after transcatheter arterial embolization in VX2 rabbit liver tumors Feng Dai,1,2 Xiuming Zhang,3 Wenrong Shen,3 Jun Chen,4 Liucheng Liu,5

Exploring the Intrinsic Piezofluorochromic Mechanism of TPE-An by STS Technique

9,10-bis(4-(1,2,2-triphenylvinyl)styryl)anthracene (TPE-An) materials have attracted considerable attention in recent years because they have high luminescence efficiency and excellent piezofluorochromic properties, which have potential applications in organic light-emitting display (OLED) area. Scanning tunneling spectroscopy (STS) technique was used to study the...