Advanced search    

Search: authors:"Jun Xu"

201 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Positive Effects of bFGF Modified Rat Amniotic Epithelial Cells Transplantation on Transected Rat Optic Nerve

Purpose Effective therapy for visual loss caused by optic nerve injury or diseases has not been achieved even though the optic nerve has the regeneration potential after injury. This study was designed to modify amniotic epithelial cells (AECs) with basic fibroblast growth factor (bFGF) gene, preliminarily investigating its effect on transected optic nerve. Methods A human bFGF...

Rickettsia raoultii in Haemaphysalis erinacei from marbled polecats, China–Kazakhstan border

We found Rickettsia raoultii DNA in 2 out of 32 (6.25 %) Haemaphysalis erinacei ticks. Result showed that the sequences of five genes (17-kDa, gltA, ompA, rrs, and ompB) were 100 % identity with that of R. Raoultii in GenBank. This study is the first report on the presence of R. raoultii in H. erinacei from wild marbled polecat, Vormela peregusna. Our findings suggest that H...

Resting-state brain activation correlates with short-time antidepressant treatment outcome in drug-naïve patients with major depressive disorder

Objective A resting-state functional magnetic resonance imaging study (fMRI) to investigate pretreatment regional differences in brain function, in patients with early treatment responsive (ERD) and early treatment nonresponsive (END) major depressive disorder (MDD).

Necrolytic migratory erythema as the first manifestation of pancreatic neuroendocrine tumor

Necrolytic migratory erythma (NME) is an obligatory paraneoplastic syndrome. Here we describe a woman admitted to the dermatology ward with NME which was later found to be associated with glucagonoma, a slow-growing, rare pancreatic neuroendocrine tumor. Even more rarely, the tumor was located in the pancreas head, while most of such lesions are located in the distal pancreas...

A Super Energy Mitigation Nanostructure at High Impact Speed Based on Buckyball System

The energy mitigation properties of buckyballs are investigated using molecular dynamics (MD) simulations. A one dimensional buckyball long chain is employed as a unit cell of granular fullerene particles. Two types of buckyballs i.e. C60 and C720 with recoverable and non-recoverable behaviors are chosen respectively. For C60 whose deformation is relatively small, a dissipative...

Characterization of the Xiamenmycin Biosynthesis Gene Cluster in Streptomyces xiamenensis 318

Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to identify a candidate gene cluster. The complete gene cluster, consisting of five genes, was confirmed by a series of gene...

The Clinical Application Value of Cytokines in Treating Infectious Diseases

We performed a prospective study to evaluate the abilities of inflammatory cytokines to rule out the potential risk of sepsis and intracranial infection and to estimate the function of inflammatory cytokines in discriminating Gram-negative bacteria from Gram-positive ones through ROC analysis. During the course of the study, Levels of serum inflammatory cytokines were measured by...

Genome Analysis and Characterisation of the Exopolysaccharide Produced by Bifidobacterium longum subsp. longum 35624™

this manuscript have the following competing interests: David Groeger, Elisa Schiavi and Ray Grant are employees of Alimentary Health Pharma Davos AG, Jun Xu is an employee of Procter & Gamble, while

Whole lung lavage combined with Granulocyte-macrophage colony stimulating factor inhalation for an adult case of refractory pulmonary alveolar proteinosis

feng Sun 0 Yan xun Wang Zuo jun Xu Hui Huang 0 Equal contributors Department of Respiratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical

Energy absorption ability of buckyball C720 at low impact speed: a numerical study based on molecular dynamics

Jun Xu 1 Yibing Li Yong Xiang 0 Xi Chen 1 0 State Key Lab of Electronic Thin Films and Integrated Devices, School of Energy Science and Engineering, University of Electronic Science and Technology

Predicting mTOR Inhibitors with a Classifier Using Recursive Partitioning and Naïve Bayesian Approaches

Background Mammalian target of rapamycin (mTOR) is a central controller of cell growth, proliferation, metabolism, and angiogenesis. Thus, there is a great deal of interest in developing clinical drugs based on mTOR. In this paper, in silico models based on multi-scaffolds were developed to predict mTOR inhibitors or non-inhibitors. Methods First 1,264 diverse compounds were...

Outermost tensile strain dominated exciton emission in bending CdSe nanowires

Artificial modulation of electronic structures and control of the transport dynamics of carriers and excitons in CdSe nanowire are important for its application in optoelectronic nanodevices. Here, we demonstrate the aggregative flow of excitons by bending CdSe nanowires. The bending strain induces spatial variance of bandgap, and the energy bandgap gradient will result in the...

Two members of TaRLK family confer powdery mildew resistance in common wheat

. Competing interests The authors declare that they have no competing interests. Authors’ contributions XEW, TTC and BQ designed the experiments. TTC, Jun Xu, WTW and CD performed the experiments. TTC, Jin

The Reversal Effects of 3-Bromopyruvate on Multidrug Resistance In Vitro and In Vivo Derived from Human Breast MCF-7/ADR Cells

Purpose P-glycoprotein mediated efflux is one of the main mechanisms for multidrug resistance in cancers, and 3-Bromopyruvate acts as a promising multidrug resistance reversal compound in our study. To test the ability of 3-Bromopyruvate to overcome P-glycoprotein-mediated multidrug resistance and to explore its mechanisms of multidrug resistance reversal in MCF-7/ADR cells, we...

Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer

Introduction Previous studies have produced controversial results regarding whether mesenchymal stem cells (MSCs) promote or inhibit tumor development. Given the dual role of MSCs in inflammation and cancer, in this study the colitis-associated colorectal cancer (CAC) model was used to examine whether umbilical cord tissue-derived MSCs could prevent neoplasm by inhibiting chronic...

Predictions for pentaquark states of hidden charm molecular nature and comparison with experiment

Liang 5 De-Min Li 4 Jun-Xu Lu 0 Vladymir K. Magas 6 Juan Nieves 3 Angels Ramos 6 Luis Roca 7 En Wang 4 Ju-Jun Xie 1 0 School of Physics and Nuclear Energy Engineering and International Research Center for

Anisotropic epitaxial ZnO/CdO core/shell heterostructure nanorods

Various surface structures and polarities of one-dimensional nanostructures offer additional control in synthesizing heterostructures suitable for optoelectronic and electronic applications. In this work, we report synthesis and characterization of ZnO-CdO nanorod-based heterostructures grown on a-plane sapphire. The heterojunction formed on the sidewall surface of the nanorod...

Different Subsets of Macrophages in Patients with New Onset Tuberculous Pleural Effusion

Objective Macrophages are the infiltrate components of tuberculous pleural effusion (TPE). This study is aimed at examining the role of different subsets of macrophages in pleural fluid (PF) and peripheral blood (PB) from patients with new onset TPE. Methods The numbers of PB and PF CD163+, CD206+ and CD115+ macrophages in 25 patients with new onset TPE and 17 healthy controls...

Clinical spectrum of intrathoracic Castleman disease: a retrospective analysis of 48 cases in a single Chinese hospital

Background Thorax is the common place to develop Castleman disease (CD), but there is no systemic clinical analysis for intrathoracic CD. Methods We conducted a retrospective analysis of 48 intrathoracic CD patients with definite pathological diagnosis who were hospitalized between 1992 and 2012 in a Chinese tertiary referral hospital. Results The study included 16 cases with...