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Economic evaluation of the breast cancer screening programme in the Basque Country: retrospective cost-effectiveness and budget impact analysis

Government , Alameda Rekalde 39, 48008 Bilbao, Bizkaia , Spain 5 Evaluation and Epidemiology Department, Hospital del Mar - IMIM (Hospital del Mar Medical Research Institute) , Passeig Maritim 25-29, 08003 ... . Arrospide A , Rue M , van Ravesteyn NT , Comas M , Larrañaga N , Sarriugarte G , Mar J . Evaluation of health benefits and harms of the breast cancer screening programme in the Basque Country . BMC Cancer

Impact of diabetes on the predictive value of heart failure biomarkers

Background Patients with diabetes mellitus (DM) have an increased risk of developing heart failure (HF). Further, DM is associated with poor prognosis in patients with HF. Our aim was to determine whether DM has any impact on the predictive value of a multi-biomarker panel in patients with HF. Methods We included 1069 consecutive ambulatory HF patients in the study: age 66.2 ± 12.8 ...

New Design for Rapid Prototyping of Digital Master Casts for Multiple Dental Implant Restorations

Aim This study proposes the replacement of all the physical devices used in the manufacturing of conventional prostheses through the use of digital tools, such as 3D scanners, CAD design software, 3D implants files, rapid prototyping machines or reverse engineering software, in order to develop laboratory work models from which to finish coatings for dental prostheses. Different ...

Advanced breast cancer clinical nursing curriculum: review and recommendations

´ ngeles Pen˜ uelas declares consultancy work for Novartis Oncology. Mar´ıa del Mar Jime´nez declares consultancy work for Novartis Oncology. Dr. Alvaro Rodriguez-Lescure declares no conflict of interest ... ://www.nice.org.uk/gui dance/cg81. Accessed 19 Mar 2015 . 7. Elaboracio´n de Gu´ıas de Pra´ctica Cl´ınica en el Sistema Nacional de Salud. Manual Metodolo´gico . In: Plan de Calidad del Sistema Nacional de Salud. 2007

The geographical distribution and prevalence of Echinococcus multilocularis in animals in the European Union and adjacent countries: a systematic review and meta-analysis

Background This study aimed to provide a systematic review on the geographical distribution of Echinococcus multilocularis in definitive and intermediate hosts in the European Union (EU) and adjacent countries (AC). The relative importance of the different host species in the life-cycle of this parasite was highlighted and gaps in our knowledge regarding these hosts were ...

Muscle cell identity requires Pax7-mediated lineage-specific DNA demethylation

Background Skeletal muscle stem cells enable the formation, growth, maintenance, and regeneration of skeletal muscle throughout life. The regeneration process is compromised in several pathological conditions, and muscle progenitors derived from pluripotent stem cells have been suggested as a potential therapeutic source for tissue replacement. DNA methylation is an important ...

Poor phenotype-genotype association in a large series of patients with Type III Bartter syndrome

Introduction Type III Bartter syndrome (BS) is an autosomal recessive renal tubule disorder caused by loss-of-function mutations in the CLCNKB gene, which encodes the chloride channel protein ClC-Kb. In this study, we carried out a complete clinical and genetic characterization in a cohort of 30 patients, one of the largest series described. By comparing with other published ...

A literature review and case report of hand, foot and mouth disease in an immunocompetent adult

Background To report an uncommon case of hand, foot and mouth disease, (HFMD) in an immunocompetent adult; a highly infectious disease, characterized by the appearance of vesicles on the mouth, hands and feet, associated with coxsackieviruses and enteroviruses; including a literature review. Case report A 23 year Caucasian male with no medical or surgical history, no allergies, was ...

Cytotoxicity of Cyanoacrylate-Based Tissue Adhesives and Short-Term Preclinical In Vivo Biocompatibility in Abdominal Hernia Repair

Pérez-Köhler Andreé Kühnhardt Mar Fernández-Gutiérrez 1 Julio San Román 1 Juan Manuel Bellón Alberto G Passi, University of Insubria, ITALY 0 Department of Medicine and Medical Specialities, Faculty of

Rheumatoid Arthritis and Incidence of Twelve Initial Presentations of Cardiovascular Disease: A Population Record-Linkage Cohort Study in England

Introduction While rheumatoid arthritis is an established risk factor for cardiovascular disease (CVD), our knowledge of how the pattern of risk varies for different cardiovascular phenotypes is incomplete. The association between rheumatoid arthritis and the initial presentation of 12 types of CVDs were examined in a contemporary population of men and women of a wide age range. ...

Many Vulnerable or a Few Resilient Specimens? Finding the Optimal for Reintroduction/Restocking Programs

. (In press) Rearing diet may determine fish restocking success: a case study of hatchery-reared juvenile meagre Argyrosomus regius . Sci Mar. 7. Leber KM , Cantrell RN , Leung P ( 2005 ) Optimizing cost ... . USA: Chapman and Hall . 570 p. 43. Law R ( 2000 ) Fishing, selection, and phenotypic evolution . ICES J Mar Sci 57 : 659 - 668 . 44. Shephard S , Fung T , Houle JE , Farnsworth KD , Reid DG , Rossberg

Difference in Restricted Mean Survival Time for Cost-Effectiveness Analysis Using Individual Patient Data Meta-Analysis: Evidence from a Case Study

Hills, Cardiff University , UNITED KINGDOM - OPEN ACCESS Data Availability Statement: Data were used with permission obtained from the MAR-LC Collaborative Group investigators, who agreed to share ... patient-level data from the Meta-Analysis of Radiotherapy in Lung Cancer (MAR-LC) collaborative group [ 19 ] which was previously used in a Dutch economic evaluation [ 20 ]. The MAR-LC comprised 2,000

Mechanism of Copper Uptake from Blood Plasma Ceruloplasmin by Mammalian Cells

Ceruloplasmin, the main copper binding protein in blood plasma, has been of particular interest for its role in efflux of iron from cells, but has additional functions. Here we tested the hypothesis that it releases its copper for cell uptake by interacting with a cell surface reductase and transporters, producing apoceruloplasmin. Uptake and transepithelial transport of copper ...

Response to the Letter to the Editor: “Radiotherapy of salivary glands as treatment of sialorrhea in patients with amyotrophic lateral sclerosis requiring non-invasive ventilation: what are we doing?”

Maladies du Syste`me Nerveux, AP-HP, Groupe hospitalier Pitie ́-Salpeˆtrie`re , 47-83, Boulevard de l'Hoˆpital, 75013 Paris , France 1 Pierre-Franc ̧ois Pradat 2 Maria del Mar Amador 3 Sorbonne Universite ́s

Relation between Liver Transaminases and Dyslipidaemia among 2-10 y.o. Northern Mexican Children

Background and Aims The increase in overweight and obese children may be linked to increased rates of liver damage and dyslipidaemia. This study aimed to explore the associations of liver biomarkers with overweight/obesity and dyslipidaemia in Mexican children. Methods The study was a population-based cross-sectional nutritional survey carried out in the State of Nuevo León, ...

Parents’ beliefs and knowledge about the management of acute otitis media: a qualitative study

provided by the Australian Government Department of Health. Tammy C Hoffmann and Chris Del Mar are chief investigators at the Centre for Research Excellence in Minimising Antibiotic Resistance from Acute ... Respiratory Infections (NHMRC grant 1044904). 1. Venekamp RP , Sanders S , Glasziou PP , Del Mar CB , Rovers MM . Antibiotics for acute otitis media in children . Cochrane Database Syst Rev . 2013 ; 1

Natural history of cerebrotendinous xanthomatosis: a paediatric disease diagnosed in adulthood

Cerebrotendinous xanthomatosis (CTX) is among the few inherited neurometabolic disorders amenable to specific treatment. It is easily diagnosed using plasma cholestanol. We wished to delineate the natural history of the most common neurological and non-neurological symptoms in thirteen patients with CTX. Diarrhea almost always developed within the first year of life. Cataract and ...

Cognitive Profile of Zonisamide and Valproic Acid in the Treatment of Idiopathic Generalized Epilepsy: A Comparative Observational Study

-Morillejo, Patricia Perea-Justicia, Mar Iglesias-Espinosa, and Tesifo´ n Parro´ n-Carren˜o have no relevant disclosures. Compliance with Ethics Guidelines. This article does not contain any new studies with