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The 100 most-cited articles on cardiovascular diseases from Mainland China

Background China, as a rapidly developing country with the largest population of cardiologist in the world, has an increasing importance in the field of cardiology. However, the quantity and quality of research production in the field of cardiology is unclear. Aims To analyze the characteristics of the high-level articles published on cardiovascular diseases in Mainland China...

CRISPR/Cas9 and TALE: beyond cut and paste

, Ruotong Ren, Jun Wu, Keiichiro Suzuki, Juan Carlos Izpisua Belmonte, and Guang-Hui Liu declare no conflict of interest. This article is distributed under the terms of the Creative Commons Attribution

De Novo Transcriptome Assembly and Characterization for the Widespread and Stress-Tolerant Conifer Platycladus orientalis

Platycladus orientalis, of the family Cupressaceae, is a widespread conifer throughout China and is extensively used for ecological reforestation, horticulture, and in medicine. Transcriptome assemblies are required for this ecologically important conifer for understanding genes underpinning adaptation and complex traits for breeding programs. To enrich the species’ genomic...

Visfatin Destabilizes Atherosclerotic Plaques in Apolipoprotein E–Deficient Mice

Objectives Although there is evidence that visfatin is associated with atherogenesis, the effect of visfatin on plaque stability has not yet been explored. Methods In vivo, vulnerable plaques were established by carotid collar placement in apolipoprotein E–deficient (ApoE−/−) mice, and lentivirus expressing visfatin (lenti-visfatin) was locally infused in the carotid artery. The...

A Longitudinal Study of Posttraumatic Stress Disorder Symptoms and Its Relationship with Coping Skill and Locus of Control in Adolescents after an Earthquake in China

Background/Objectives Post-traumatic stress disorder is a common psychological maladaptation among adolescents after undergoing an earthquake. Knowledge about the prevalence and maintenance of post-traumatic stress disorder symptoms and the changes of its predictors over time can help medical providers assist adolescent survivors with mitigating long-term impacts. This study...

Application of passive source surface-wave method in site engineering seismic survey

Site engineering seismic survey provides basic data for seismic effect analysis. As an important parameter of soil, shear-wave velocity is usually obtained through wave velocity testing in borehole. In this paper, the passive source surface-wave method is introduced into the site engineering seismic survey and practically applied in an engineering site of Shijingshan District. By...

Design-oriented modeling of circular FRP-wrapped concrete columns after sustained axial compression

. 201306210079), and the Natural Science Foundation of Beijing (No. 8144051) , China ORCID: Hui LIU, http://orcid.org/0000-0003-0613-2031; Ming- hua HE , http://orcid.org/0000-0001-5390-7915 c Zhejiang University

Outcome benefit of abdominal paracentesis drainage for severe acute pancreatitis patients with serum triglyceride elevation by decreasing serum lipid metabolites

carried out the retrospective study. They were responsible for the conception, design of the study and the development of methodology. Hong-yu Sun, Tao Chen, Hong-tao Yan, Wei-hui Liu, Jing Zhou and Tao

Towards developing a robot assistant for uterus positioning during hysterectomy: system design and experiments

Yun-hui Liu 0 0 Equal contributors Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong , Shatin, N.T. , Hong Kong Background: In traditional laparoscopic

Nosocomial Infection in Adult Admissions with Hematological Malignancies Originating from Different Lineages: A Prospective Observational Study

Background Nosocomial infection (NI) causes prolonged hospital stays, increased healthcare costs, and higher mortality among patients with hematological malignancies (HM). However, few studies have compared the incidence of NI according to the HM lineage. Objective To compare the incidence of NI according to the type of HM lineage, and identify the risk factors for NI. Methods...

Suppression of histone deacetylation promotes the differentiation of human pluripotent stem cells towards neural progenitor cells

Background Emerging studies of human pluripotent stem cells (hPSCs) raise new prospects for neurodegenerative disease modeling and cell replacement therapies. Therefore, understanding the mechanisms underlying the commitment of neural progenitor cells (NPCs) is important for the application of hPSCs in neurodegenerative disease therapies. It has been reported that epigenetic...

Vitamin C alleviates aging defects in a stem cell model for Werner syndrome

Ye, Yu Wang, Jian Li, Jie Qiao, Jing Qu, Weiqi Zhang, and Guang-Hui Liu declare that they have no conflict of interest. All institutional and national guidelines for the care and use of laboratory

Coverage, use and maintenance of bed nets and related influence factors in Kachin Special Region II, northeastern Myanmar

Background Myanmar is one of the 31 highest burden malaria countries worldwide. Scaling up the appropriate use of insecticide-treated nets (ITNs) is a national policy for malaria prevention and control. However, the data on use, influencing factors and maintenance of bed nets is still lack among the population in Kachin Special Region II (KR2), Northeastern Myanmar. Methods The...

PpYUC11, a strong candidate gene for the stony hard phenotype in peach (Prunus persica L. Batsch), participates in IAA biosynthesis during fruit ripening

High concentrations of indole-3-acetic acid (IAA) are required for climacteric ethylene biosynthesis to cause fruit softening in melting flesh peaches at the late ripening stage. By contrast, the fruits of stony hard peach cultivars do not soften and produce little ethylene due to the low IAA concentrations. To investigate the regulation of IAA accumulation during peach ripening...

Preliminary Proteomic Analysis of A549 Cells Infected with Avian Influenza Virus H7N9 and Influenza A Virus H1N1

A newly emerged H7N9 influenza virus poses high risk to human beings. However, the pathogenic mechanism of the virus remains unclear. The temporal response of primary human alveolar adenocarcinoma epithelial cells (A549) infected with H7N9 influenza virus and H1N1 influenza A virus (H1N1, pdm09) were evaluated using the proteomics approaches (2D-DIGE combined with MALDI-TOF-MS/MS...

Protein function prediction by collective classification with explicit and implicit edges in protein-protein interaction networks

analysis, and drafted the manuscript. Hui Liu prepared the datasets. Acknowledgements Based on Effectively predicting protein functions by collective classification An extended abstract, by Wei Xiong, Hui ... Program (grant No. 2012AA020403) and 973 program (grant No. 2010CB126604). Hui Liu was supported by NSFC (grant No. 31100954). Jihong Guan was supported by NSFC (grant No. 61173118), Shuigeng Zhou was also

Two ultraviolet radiation datasets that cover China

Ultraviolet (UV) radiation has significant effects on ecosystems, environments, and human health, as well as atmospheric processes and climate change. Two ultraviolet radiation datasets are described in this paper. One contains hourly observations of UV radiation measured at 40 Chinese Ecosystem Research Network stations from 2005 to 2015. CUV3 broadband radiometers were used to...

Physiological and Comparative Proteomic Analysis Reveals Different Drought Responses in Roots and Leaves of Drought-Tolerant Wild Wheat (Triticum boeoticum)

To determine the proteomic-level responses of drought tolerant wild wheat (Triticum boeoticum), physiological and comparative proteomic analyses were conducted using the roots and the leaves of control and short term drought-stressed plants. Drought stress was imposed by transferring hydroponically grown seedlings at the 3-leaf stage into 1/2 Hoagland solution containing 20% PEG...