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Necrolytic migratory erythema as the first manifestation of pancreatic neuroendocrine tumor

Necrolytic migratory erythma (NME) is an obligatory paraneoplastic syndrome. Here we describe a woman admitted to the dermatology ward with NME which was later found to be associated with glucagonoma, a slow-growing, rare pancreatic neuroendocrine tumor. Even more rarely, the tumor was located in the pancreas head, while most of such lesions are located in the distal pancreas...

New Approaches for Studying Alcoholic Liver Disease

models of ALD are providing new insights into the pathogenesis of the different stages of ALD, which may provide new targets for therapy. Compliance with Ethics Guidelines Conflict of Interest Jun Xu

Tunable nonlinear optical properties in nanocrystalline Si/SiO2 multilayers under femtosecond excitation

The nonlinear optical properties of nanocrystalline-Si/SiO2 (nc-Si/SiO2) multilayers have been investigated through Z-scan technique by using a Ti-sapphire laser with 50-fs pulse duration at 800 nm as a pump laser. It is interesting to note that with increasing the annealing temperature to make the sample change from amorphous phase to nanocrystalline state, the nonlinear...

Effects of reduced β2-glycoprotein I on the expression of aortic matrix metalloproteinases and tissue inhibitor matrix metalloproteinases in diabetic mice

Background Reduced β2-glycoprotein I (reduced β2GP I), which has free sulfhydryl groups, is present in plasma and serum; it can protect vascular endothelial cells from damage due to oxidative stress in vitro. We investigated the effects of reduced β2GP I on the expression of various matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the...

On the Utility of Short Echo Time (TE) Single Voxel 1H–MRS in Non–Invasive Detection of 2–Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel

Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) are frequently found in brain tumors, and the resulting onco–metabolite, 2–hydroxyglutarate (2HG), has been suggested to be a potential diagnostic and prognostic biomarker of the diseases. Indeed, recent studies have demonstrated the feasibility of non–invasively detecting 2HG by using proton magnetic resonance spectroscopy...

A Super Energy Mitigation Nanostructure at High Impact Speed Based on Buckyball System

The energy mitigation properties of buckyballs are investigated using molecular dynamics (MD) simulations. A one dimensional buckyball long chain is employed as a unit cell of granular fullerene particles. Two types of buckyballs i.e. C60 and C720 with recoverable and non-recoverable behaviors are chosen respectively. For C60 whose deformation is relatively small, a dissipative...

Resting-state brain activation correlates with short-time antidepressant treatment outcome in drug-naïve patients with major depressive disorder

Objective A resting-state functional magnetic resonance imaging study (fMRI) to investigate pretreatment regional differences in brain function, in patients with early treatment responsive (ERD) and early treatment nonresponsive (END) major depressive disorder (MDD).

Identification and characterization of microRNAs in Baylisascaris schroederi of the giant panda

Guang-Hui Zhao 1 Min-Jun Xu 0 Xing-Quan Zhu 0 0 State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research

Moving Object Detection and Shadow Removing under Changing Illumination Condition

no. 2013QC024. Jun Xu is supported by the National Natural Science Foundation of China under Grant no. 11204099 and self-determined research funds of CCNU from the colleges basic research and operation

Moving Object Detection and Shadow Removing under Changing Illumination Condition

no. 2013QC024. Jun Xu is supported by the National Natural Science Foundation of China under Grant no. 11204099 and self-determined research funds of CCNU from the colleges basic research and operation

Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts

]. Disclosure Xiao Liu and Jun Xu declare that they have no conflict of interest. David A. Brenner holds a patent for inducing inactivation of fibrogenic myofibroblasts. Tatiana Kisseleva holds a patent for

Energy absorption ability of buckyball C720 at low impact speed: a numerical study based on molecular dynamics

Jun Xu 1 Yibing Li Yong Xiang 0 Xi Chen 1 0 State Key Lab of Electronic Thin Films and Integrated Devices, School of Energy Science and Engineering, University of Electronic Science and Technology

Outermost tensile strain dominated exciton emission in bending CdSe nanowires

Artificial modulation of electronic structures and control of the transport dynamics of carriers and excitons in CdSe nanowire are important for its application in optoelectronic nanodevices. Here, we demonstrate the aggregative flow of excitons by bending CdSe nanowires. The bending strain induces spatial variance of bandgap, and the energy bandgap gradient will result in the...

Molding acoustic, electromagnetic and water waves with a single cloak

, Electrical, and Mathematical Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi ArabiaMohamed Farhat AuthorsSearch for Jun Xu in:Nature Research

Whole lung lavage combined with Granulocyte-macrophage colony stimulating factor inhalation for an adult case of refractory pulmonary alveolar proteinosis

feng Sun 0 Yan xun Wang Zuo jun Xu Hui Huang 0 Equal contributors Department of Respiratory Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical

Quad-PRE: A Hybrid Method to Predict Protein Quaternary Structure Attributes

The protein quaternary structure is very important to the biological process. Predicting their attributes is an essential task in computational biology for the advancement of the proteomics. However, the existing methods did not consider sufficient properties of amino acid. To end this, we proposed a hybrid method Quad-PRE to predict protein quaternary structure attributes using...

Rickettsia raoultii in Haemaphysalis erinacei from marbled polecats, China–Kazakhstan border

We found Rickettsia raoultii DNA in 2 out of 32 (6.25 %) Haemaphysalis erinacei ticks. Result showed that the sequences of five genes (17-kDa, gltA, ompA, rrs, and ompB) were 100 % identity with that of R. Raoultii in GenBank. This study is the first report on the presence of R. raoultii in H. erinacei from wild marbled polecat, Vormela peregusna. Our findings suggest that H...

Mechanism of Water Infiltration and Defiltration through ZSM-5 Zeolite: Heating and Sodium Chloride Concentration Effect

Hydrophobic nanoporous material and wetting liquid together comprise a system with promising energy related applications. The mechanism of the interaction between liquid and solid phase is not fully explored. In this paper, based on the quasistatic compression experiments on investigating the mechanical behavior of ZSM-5 zeolite/NaCl solution system, the effects of two key...

Mechanism of Water Infiltration and Defiltration through ZSM-5 Zeolite: Heating and Sodium Chloride Concentration Effect

Hydrophobic nanoporous material and wetting liquid together comprise a system with promising energy related applications. The mechanism of the interaction between liquid and solid phase is not fully explored. In this paper, based on the quasistatic compression experiments on investigating the mechanical behavior of ZSM-5 zeolite/NaCl solution system, the effects of two key...

Positive Effects of bFGF Modified Rat Amniotic Epithelial Cells Transplantation on Transected Rat Optic Nerve

Purpose Effective therapy for visual loss caused by optic nerve injury or diseases has not been achieved even though the optic nerve has the regeneration potential after injury. This study was designed to modify amniotic epithelial cells (AECs) with basic fibroblast growth factor (bFGF) gene, preliminarily investigating its effect on transected optic nerve. Methods A human bFGF...