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eHUGS: Enhanced Hierarchical Unbiased Graph Shrinkage for Efficient Groupwise Registration

Effective and efficient spatial normalization of a large population of brain images is critical for many clinical and research studies, but it is technically very challenging. A commonly used approach is to choose a certain image as the template and then align all other images in the population to this template by applying pairwise registration. To avoid the potential bias...

Modelling the Influence of Awareness Programs by Media on the Drinking Dynamics

, China Received 25 January 2014; Accepted 17 March 2014; Published 16 April 2014 Academic Editor: Yongli Song Copyright © 2014 Hai-Feng Huo and Qian Wang. This is an open access article distributed

The Paracrine Effect of Transplanted Human Amniotic Epithelial Cells on Ovarian Function Improvement in a Mouse Model of Chemotherapy-Induced Primary Ovarian Insufficiency

Wang, Minhua Xu, Qiuwan Zhang, Ting Li, and Dongmei Lai The Center of Research Laboratory and Department of Gynecology, The International Peace Maternity and Child Health Hospital, School of Medicine

Solutions of the boundary value problem for a 2nth-order nonlinear difference equation containing both advance and retardation

In this paper, we consider the boundary value problem for a 2nth-order nonlinear difference equation containing both advance and retardation. By using the critical point theory, some sufficient conditions of the existence of solutions of the boundary value problem are obtained. The proof is based on the linking theorem. An example is given to illustrate our results.

A retrospective analysis of eleven cases of invasive rhino-orbito-cerebral mucormycosis presented with orbital apex syndrome initially

Background Rhino-orbito-cerebral mucormycosis(ROCM) is an invasive fungal infection that usually occurs in immunocompromised patients and sometimes presents as orbital apex syndrome(OAS) initially. It is rapidly fatal without an early diagnosis and treatment. We report the cases of invasive ROCM presenting with OAS initially in order to raise the attention of clinicians. Methods...

A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses

Medical Molecular Virology of MOE/MOH, School of Basic Medical Sciences and Shanghai Public Health Clinical Center, Fudan University, Shanghai 200032, ChinaYufeng Yu, Peng Zou, Qian Wang, Yanyan Dai, Fei Yu ... for Peng Zou in:Nature Research journals • PubMed • Google ScholarSearch for Qian Wang in:Nature Research journals • PubMed • Google ScholarSearch for Yanyan Dai in:Nature Research journals • PubMed

Hairy/enhancer of Split Homologue-1 Suppresses Vascular Endothelial Growth Factor-induced Angiogenesis via Downregulation of Osteopontin Expression

Center, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, ChinaLei Zheng, Qian Wang & Yan-Wei HuDepartment of Cardio vascular Surgery, China- Japan Friendship Hospital, Beijing, 100029 ... journals • PubMed • Google Scholar Search for Qian Wang in:Nature Research journals • PubMed • Google Scholar Search for Zhi-Qi Lin in:Nature Research journals • PubMed • Google Scholar Search for Hao Liu

Use of Pulmonary Artery Catheter in Coronary Artery Bypass Graft. Costs and Long-Term Outcomes

Background Pulmonary artery catheters (PAC) are used widely to monitor hemodynamics in patients undergoing coronary bypass graft (CABG) surgery. However, recent studies have raised concerns regarding both the effectiveness and safety of PAC. Therefore, our aim was to determine the effects of the use of PAC on the short- and long-term health and economic outcomes of patients...

Amine/acid composite Janus nanosheets

Janus materials have witnessed fast development due to their diversified promising performances and practical applications. Compared with their spherical counterparts, Janus nanosheets have gained more concerns for their highly anisotropic shape besides chemistry. Herein, 3.5 nm ultrathin and flexible Janus nanosheets with carboxyl group terminated onto one side are fabricated by...

A transcriptome profile in hepatocellular carcinomas based on integrated analysis of microarray studies

Background Despite new treatment options for hepatocellular carcinomas (HCC) recently, 5-year survival remains poor, ranging from 50 to 70%, which may attribute to the lack of early diagnostic biomarkers. Thus, developing new biomarkers for early diagnosis of HCC, is extremely urgent, aiming to decrease HCC-related deaths. Methods In the study, we conducted a comprehensive...

Janus colloidal copolymers

We propose a new type of nanocomposite that we call Janus colloidal copolymers (JCCPs). JCCPs have two different polymers conjugated on opposite sides of a nanosized colloid. Janus clusters of copolymer PS-b-PAA (where PS is polystyrene and PAA is poly(acrylic acid)) are self-organized within confined mesoporous silica channels onto the surface of iron oxide (Fe3O4) core...

Spatiotemporal hierarchy in antibody recognition against transmitted HIV-1 envelope glycoprotein during natural infection

Background Majority of HIV-1 infection is established by one transmitted/founder virus and understanding how the neutralizing antibodies develop against this virus is critical for our rational design an HIV-1 vaccine. Results We report here antibody profiling of sequential plasma samples against transmitted/founder HIV-1 envelope glycoprotein in an epidemiologically linked...

Re-Identification Risk versus Data Utility for Aggregated Mobility Research Using Mobile Phone Location Data

Mobile phone location data is a newly emerging data source of great potential to support human mobility research. However, recent studies have indicated that many users can be easily re-identified based on their unique activity patterns. Privacy protection procedures will usually change the original data and cause a loss of data utility for analysis purposes. Therefore, the need...

Morphology Control for Al2O3 Inclusion Without Ca Treatment in High-Aluminum Steel

Nozzle blockage is a major problem during continuous casting of Al-containing steel. Herein, we analyzed the thermodynamic equilibrium behavior between aluminum and oxygen in steel at 1873 K (1600 °C) and demonstrated that, the dissolved [O] initially decreases with increasing the dissolved [Al] until approximately 0.1 wt pct [Al], and after that, the dissolved [O] increases with...

Hydrodeoxygenation of water-insoluble bio-oil to alkanes using a highly dispersed Pd–Mo catalyst

Search for Xusheng Zheng in:Nature Research journals • PubMed • Google Scholar Search for Shufang Ji in:Nature Research journals • PubMed • Google Scholar Search for Qian Wang in:Nature Research journals

Optimal Routing for Heterogeneous Fixed Fleets of Multicompartment Vehicles

© 2014 Qian Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

A rapid and reliable strategy for chromosomal integration of gene(s) with multiple copies

ChinaPengfei Gu, Fan Yang, Tianyuan Su, Qian Wang, Quanfeng Liang & Qingsheng Qi AuthorsSearch for Pengfei Gu in:Nature Research journals • PubMed • Google ScholarSearch for Fan Yang in:Nature Research journals ... • PubMed • Google ScholarSearch for Tianyuan Su in:Nature Research journals • PubMed • Google ScholarSearch for Qian Wang in:Nature Research journals • PubMed • Google ScholarSearch for Quanfeng Liang

A New Method to Simulate Free Surface Flows for Viscoelastic Fluid

Free surface flows arise in a variety of engineering applications. To predict the dynamic characteristics of such problems, specific numerical methods are required to accurately capture the shape of free surface. This paper proposed a new method which combined the Arbitrary Lagrangian-Eulerian (ALE) technique with the Finite Volume Method (FVM) to simulate the time-dependent...

The Calcium Sensor CBL-CIPK Is Involved in Plant’s Response to Abiotic Stresses

Abiotic stress halts the physiological and developmental process of plant. During stress condition, CBL-CIPK complex is identified as a primary element of calcium sensor to perceive environmental signals. Recent studies established that this complex regulates downstream targets like ion channels and transporters in adverse stages conditions. Crosstalks between the CBL-CIPK...

Rice black streaked dwarf virus P7-2 forms a SCF complex through binding to Oryza sativa SKP1-like proteins, and interacts with GID2 involved in the gibberellin pathway

As a core subunit of the SCF complex that promotes protein degradation through the 26S proteasome, S-phase kinase-associated protein 1 (SKP1) plays important roles in multiple cellular processes in eukaryotes, including gibberellin (GA), jasmonate, ethylene, auxin and light responses. P7-2 encoded by Rice black streaked dwarf virus (RBSDV), a devastating viral pathogen that...