amount of isopropanol in PBS without RH-2485 was injected. Authors' contributions Jia-Lin Wang carried out immunoblotting. Xiao-Juan Jiang performed Northern blot. Qian Wang completed immunohistochemistry
Introduction Tyrosine kinases are key mediators of multiple signaling pathways implicated in rheumatoid arthritis (RA). We previously demonstrated that imatinib mesylate--a Food and Drug Administration (FDA)-approved, antineoplastic drug that potently inhibits the tyrosine kinases Abl, c-Kit, platelet-derived growth factor receptor (PDGFR), and c-Fms--ameliorates murine...
