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Cadmium Accumulation and Metallothionein Biosynthesis in Cadmium-Treated Freshwater Mussel Anodonta woodiana

This study investigated the distribution of cadmium (Cd) and the protein level of metallothionein (MT) and examined the relationship of Cd accumulation and the MT concentration in different tissues of freshwater mussel Anodonta woodiana following Cd treatment. The mussels were exposed to Cd (4.21, 8.43, 16.86, 33.72 and 67.45 mg L-1) for 24, 48, 72 and 96 h, respectively. After...

Fixed point theorems for complex non-self mappings satisfying an implicit relation in Kaleva-Seikkala’s type fuzzy metric spaces

In this paper, by using A φ -type real functions, some fixed point theorems for complex non-self mappings satisfying an implicit relation in two fuzzy metric spaces in the sense of Kaleva and Seikkala are established. As applications, we obtain the corresponding fixed point theorems for complex non-self mappings satisfying an implicit relation in two Menger probabilistic metric...

Mode-matching metasurfaces: coherent reconstruction and multiplexing of surface waves

, Singapore) for his assistance in preparing the samples. Author information Author notesJiao Lin & Qian Wang These authors contributed equally to this work. AffiliationsInstitute of Micro & Nano Optics ... , Nanyang Technological University, Singapore 637371, SingaporeGuanghui Yuan AuthorsSearch for Jiao Lin in:Nature Research journals • PubMed • Google ScholarSearch for Qian Wang in:Nature Research journals

Discovery of Novel Allosteric Effectors Based on the Predicted Allosteric Sites for Escherichia coli D-3-Phosphoglycerate Dehydrogenase

D-3-phosphoglycerate dehydrogenase (PGDH) from Escherichia coli catalyzes the first critical step in serine biosynthesis, and can be allosterically inhibited by serine. In a previous study, we developed a computational method for allosteric site prediction using a coarse-grained two-state Gō Model and perturbation. Two potential allosteric sites were predicted for E. coli PGDH...

Multiple Genetic Modifiers of Bilirubin Metabolism Involvement in Significant Neonatal Hyperbilirubinemia in Patients of Chinese Descent

The potential for genetic variation to modulate neonatal hyperbilirubinemia risk is increasingly being recognized. A case-control study was designed to assess comprehensive contributions of the multiple genetic modifiers of bilirubin metabolism on significant neonatal hyperbilirubinemia in Chinese descendents. Eleven common mutations and polymorphisms across five bilirubin...

Indoleamine 2,3-Dioxygenase Is Involved in the Inflammation Response of Corneal Epithelial Cells to Aspergillus fumigatus Infections

Indoleamine 2,3-dioxygenase (IDO), which is mainly expressed in activated dendritic cells, is known as a regulator of immune responses. However, the role of IDO in immune responses against fungal corneal infection has not been investigated. To evaluate the regulatory mechanisms of IDO in fungal inflammation, we resorted to human corneal epithelial cells (HCECs), known as the...

Construction of porous cationic frameworks by crosslinking polyhedral oligomeric silsesquioxane units with N-heterocyclic linkers

-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing Tech University, Nanjing 210009, ChinaGuojian Chen, Yu Zhou, Xiaochen Wang, Jing Li, Shuang Xue, Yangqing Liu, Qian Wang ... Yangqing Liu in:Nature Research journals • PubMed • Google ScholarSearch for Qian Wang in:Nature Research journals • PubMed • Google ScholarSearch for Jun Wang in:Nature Research journals • PubMed • Google

The role of Syk signaling in antifungal innate immunity of human corneal epithelial cells

Wang 0 Liting Hu 0 0 Department of Ophthalmology, the Affiliated Hospital of Qingdao University , Qingdao 266003, Shandong Province , China 1 Department of Ophthalmology, the Affiliated Hospital of

Filamin-A Increases the Stability and Plasma Membrane Expression of Polycystin-2

Polycystin-2 (PC2), encoded by the PKD2 gene, is mutated in ~15% of autosomal dominant polycystic kidney disease. Filamins are actin-binding proteins implicated in scaffolding and membrane stabilization. Here we studied the effects of filamin on PC2 stability using filamin-deficient human melanoma M2, filamin-A (FLNA)-replete A7, HEK293 and IMCD cells together with FLNA siRNA...

Identification and characterization of epithelial cells derived from human ovarian follicular fluid

Introduction Follicular fluid is important for follicular development and oocyte maturation. Evidence suggests that follicular fluid is not only rich in proteins but cells. Besides oocytes, the follicular fluid contains granulosa, thecal, and ovarian surface epithelial cells, and both granulosa and thecal cells are well-characterized. However, epithelial cells in follicular fluid...

Establishment and genetic characterization of a novel mixed-phenotype acute leukemia cell line with EP300-ZNF384 fusion

Herein, we describe the establishment and characterization of the first mixed-phenotype acute leukemia cell line (JIH-5). The JIH-5 cell line was established from leukemia cells with B lymphoid/myeloid phenotype from a female mixed-phenotype acute leukemia patient. JIH-5 cells exhibit an immunophenotype comprised of myeloid and B lymphoid antigens. Whole-exome sequencing revealed...

Domain-Oriented Subject Aware Model for Multimedia Data Retrieval

With the increment of the scale of internet information as well as the cross-correlation interaction, how to achieve accurate retrieval of multimedia data is an urgent question in terms of efficiently utilizing information resources. However, existing information retrieval approaches provide only limited capabilities to search multimedia data. In order to improve the ability of...

Synergistic Effect and Molecular Mechanism of Homoharringtonine and Bortezomib on SKM-1 Cell Apoptosis

Background Myelodysplastic syndromes (MDS) are clonal marrow stem-cell disorders with a high risk of progression to acute myeloid leukemia (AML). Treatment options are limited and targeted therapies are not available for MDS. In the present study, we investigated the cytotoxicity and the molecular mechanism of Homoharringtonine (HHT) and Bortezomib towards high-risk MDS cell line...

Does the Couse of Astragalus-Containing Chinese Herbal Prescriptions and Radiotherapy Benefit to Non-Small-Cell Lung Cancer Treatment: A Meta-Analysis of Randomized Trials

Qian Wang, and Yang Zhao Department of Respiratory Medicine, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, 155 Hanzhong Road, Nanjing ... Qian Wang) independently identified studies. 2.2. Inclusion Criteria Studies included in the meta-analysis had to meet all of the following criteria. (1) Participants: NSCLC patients had to be diagnosed

Analyzing Cold Tolerance Mechanism in Transgenic Zebrafish (Danio rerio)

Low temperatures may cause severe growth inhibition and mortality in fish. In order to understand the mechanism of cold tolerance, a transgenic zebrafish Tg (smyd1:m3ck) model was established to study the effect of energy homeostasis during cold stress. The muscle-specific promoter Smyd1 was used to express the carp muscle form III of creatine kinase (M3-CK), which maintained...

Parameters Optimization of Curtain Grouting Reinforcement Cycle in Yonglian Tunnel and Its Application

For practical purposes, the curtain grouting method is an effective method to treat geological disasters and can be used to improve the strength and permeability resistance of surrounding rock. Selection of the optimal parameters of grouting reinforcement cycle especially reinforcement cycle thickness is one of the most interesting areas of research in curtain grouting designs...

HANABA TARANU regulates the shoot apical meristem and leaf development in cucumber (Cucumis sativus L.)

The shoot apical meristem (SAM) is essential for continuous organogenesis in higher plants, while the leaf is the primary source organ and the leaf shape directly affects the efficiency of photosynthesis. HANABA TARANU (HAN) encodes a GATA3-type transcription factor that functions in floral organ development, SAM organization, and embryo development in Arabidopsis, but is...

Elastohydrodynamic lubrication properties and friction behaviors of several ester base stocks

Company , SINOPEC, Chongqing 400039 , China 5 Qian WANG. She received her Ph.D degree from Northwestern University, USA, 1993. She taught for five years at Florida International University , Miami, FL, USA

Lipid production from corn stover by the oleaginous yeast Cryptococcus curvatus

Background Microbial lipids produced from lignocellulosic biomass hold great promise for the biodiesel industry. These lipids usually consist of three major processes: pretreatment, enzymatic hydrolysis and lipid production. However, the conventional strategy of using biomass hydrolysates as the feedstock for lipid production suffers from low lipid coefficient and prohibitively...

HANABA TARANU (HAN) Bridges Meristem and Organ Primordia Boundaries through PINHEAD, JAGGED, BLADE-ON-PETIOLE2 and CYTOKININ OXIDASE 3 during Flower Development in Arabidopsis

Shoot organ primordia are initiated from the shoot apical meristem and develop into leaves during the vegetative stage, and into flowers during the reproductive phase. Between the meristem and the newly formed organ primordia, a boundary with specialized cells is formed that separates meristematic activity from determinate organ growth. Despite interactions that have been found...