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Distinguishing between determinate and indeterminate growth in a long-lived mammal

ghorensis can inform their conservation management . Aquat Conserv Mar Freshw Ecosyst . 2015 ; 25 : 61 - 70 . 26. Arlinghaus R , Matsumura S , Dieckmann U. The conservation and fishery benefits of protecting ... a monogamous and monomorphic mammal: The case of Alpine marmots . Oecologia . 2013 ; 172 : 427 - 36 . 36. Hayward AD , Mar KU , Lahdenperä M , Lummaa V. Early reproductive investment, senescence and

Multicentric randomized clinical trial to evaluate the long-term effectiveness of a motivational intervention against smoking, based on the information obtained from spirometry in primary care: the RESET study protocol

Background Spirometry is the recommended method of evaluating pulmonary function when respiratory disease is suspected in smokers. Nonetheless, no evidence exists of the usefulness of information obtained from this test as a motivational strategy for smoking cessation. The primary objective of this study is to evaluate the effectiveness of a motivational intervention based on ...

Review of a two-year methicillin-resistant Staphylococcus aureus screening program and cost-effectiveness analysis in Singapore

Background Methicillin-resistant Staphylococcus aureus (MRSA) poses an increasingly large disease and economic burden worldwide. The effectiveness of screening programs in the tropics is poorly understood. The aims of this study are: (i) to analyze the factors affecting MRSA colonization at admission and acquisition during hospitalization and (ii) to evaluate the cost-effectiveness ...

Regulation of constitutive and alternative mRNA splicing across the human transcriptome by PRPF8 is determined by 5′ splice site strength

Research Council Cancer Unit, University of Cambridge , Cambridge Biomedical Campus, Box 197, Cambridge CB2 0XZ , UK 1 Vihandha O. Wickramasinghe and Mar Gonzàlez-Porta are joint first authors. John C

Fitting the epidemiology and neuropathology of the early stages of Alzheimer’s disease to prevent dementia

. Clinicoecon Outcomes Res . 2011 ; 3 : 189 - 95 . 14. Mar J , Arrospide A , Comas M. Budget impact analysis of thrombolysis for stroke in Spain: a discrete event simulation model . Value Health . 2010 ; 13 : 69 ... population-based cohorts: Neurologic Diseases in the Elderly Research group . Neurology . 2000 ; 54 : S4 - 9 . 17. Karnon J , Stahl J , Brennan A , Caro JJ , Mar J , Möller J , et al. Modeling using discrete

Should central venous catheter be systematically removed in patients with suspected catheter related infection?

Introduction Best clinical practice for patients with suspected catheter-related infection (CRI) remains unclear according to the latest Infectious Diseases Society of America (IDSA) guidelines. Thus, the objective of this study was to analyze clinical practice concerning the central venous catheter (CVC) and its impact on prognosis in patients with suspected CRI. Methods We ...

Gut Microbiota Dynamics during Dietary Shift in Eastern African Cichlid Fishes

, 4 Evolutionary Genomics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM) , Barcelona , Spain , 5 University Pompeu Fabra (UPF) , Barcelona , Spain , 6 Catalan Institution for Research

What is the effect of a formalised trauma tertiary survey procedure on missed injury rates in multi-trauma patients? Study protocol for a randomised controlled trial

; 39 : 107 - 14 . 2. Keijzers GB , Giannakopolous GF , Del Mar C , Bakker FC , Geeraedts Jr LM . The effect of tertiary surveys on missed injuries in trauma: a systematic review . Scand J Trauma Resusc

Complex Genotype Mixtures Analyzed by Deep Sequencing in Two Different Regions of Hepatitis B Virus

This study assesses the presence and outcome of genotype mixtures in the polymerase/surface and X/preCore regions of the HBV genome in patients with chronic hepatitis B virus (HBV) infection. Thirty samples from ten chronic hepatitis B patients were included. The polymerase/surface and X/preCore regions were analyzed by deep sequencing (UDPS) in the first available sample at ...

Quantifying sequence and structural features of protein–RNA interactions

Increasing awareness of the importance of protein–RNA interactions has motivated many approaches to predict residue-level RNA binding sites in proteins based on sequence or structural characteristics. Sequence-based predictors are usually high in sensitivity but low in specificity; conversely structure-based predictors tend to have high specificity, but lower sensitivity. Here we ...

Development and Characterization of an Effective Food Allergy Model in Brown Norway Rats

Background Food allergy (FA) is an adverse health effect produced by the exposure to a given food. Currently, there is no optimal animal model of FA for the screening of immunotherapies or for testing the allergenicity of new foods. Objective The aim of the present study was to develop an effective and rapid model of FA in Brown Norway rats. In order to establish biomarkers of FA ...

Calmodulin 2 Mutation N98S Is Associated with Unexplained Cardiac Arrest in Infants Due to Low Clinical Penetrance Electrical Disorders

Background Calmodulin 1, 2 and 3 (CALM) mutations have been found to cause cardiac arrest in children at a very early age. The underlying aetiology described is long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT) and idiopathic ventricular fibrillation (IVF). Little phenotypical data about CALM2 mutations is available. Objectives The aim of this ...

Factors Controlling Vegetation Fires in Protected and Non-Protected Areas of Myanmar

): 5403 - 5408 . PMID: 16554375 30. Lambin EF , Meyfroidt P. Global land use change, economic globalization, and the looming land scarcity . Proc Natl Acad Sci U S A. 2011 Mar 1 ; 108 ( 9 ): 3465 - 3472 ... areas in the Brazilian Amazon . Proc Natl Acad Sci U S A. 2013 Mar 26 ; 110 ( 13 ): 4956 - 4961 . doi: 10.1073/pnas.1214786110 PMID: 23479648 36. Nolte C , Agrawal A. Linking management effectiveness

Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis

Chronic liver diseases are characterized by a sustained inflammatory response in which chemokines and chemokine-receptors orchestrate inflammatory cell recruitment. In this study we investigated the role of the chemokine receptor CCR6 in acute and chronic liver injury. In the absence of liver injury Ccr6-/- mice presented a higher number of hepatic macrophages and increased ...

LA EVALUACIÓN ORIENTADA AL APRENDIZAJE DEL INGLÉS

European Scientific Journal July 2014 edition vol.10 LA EVALUACIN ORIENTADA AL APRENDIZAJE DEL INGLS Mara del Mar Palenzuela Prez 0 Noem Reina Ruz 0 MA 0 0 University of Almeria , Spain Evaluation

Conservative site-specific and single-copy transgenesis in human LINE-1 elements

Genome engineering of human cells plays an important role in biotechnology and molecular medicine. In particular, insertions of functional multi-transgene cassettes into suitable endogenous sequences will lead to novel applications. Although several tools have been exploited in this context, safety issues such as cytotoxicity, insertional mutagenesis and off-target cleavage ...

Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer

Background Misregulation of the PTGS (prostaglandin endoperoxide synthase, also known as cyclooxygenase or COX) pathway may lead to the accumulation of pro-inflammatory signals, which constitutes a hallmark of cancer. To get insight into the role of this signaling pathway in colorectal cancer (CRC), we have characterized the transcriptional and epigenetic landscapes of the PTGS ...

ATG18 and FAB1 Are Involved in Dehydration Stress Tolerance in Saccharomyces cerevisiae

Recently, different dehydration-based technologies have been evaluated for the purpose of cell and tissue preservation. Although some early results have been promising, they have not satisfied the requirements for large-scale applications. The long experience of using quantitative trait loci (QTLs) with the yeast Saccharomyces cerevisiae has proven to be a good model organism for ...

Individual Shrink Wrapping of Zucchini Fruit Improves Postharvest Chilling Tolerance Associated with a Reduction in Ethylene Production and Oxidative Stress Metabolites

We have studied the effect of individual shrink wrapping (ISW) on the postharvest performance of refrigerated fruit from two zucchini cultivars that differ in their sensitivity to cold storage: Sinatra (more sensitive) and Natura (more tolerant). The fruit was individually shrink wrapped before storing at 4°C for 0, 7 and 14 days. Quality parameters, ethylene and CO2 productions, ...

INTRAPERSONAL INTELLIGENCE AND MOTIVATION IN FOREIGN LANGUAGE LEARNING

Maria del Mar Palenzuela Perez 0 Noemi Reina Ruz 0 MA 0 0 University of Almeria , Spain The Multiple Intelligences Theory proposes a pluralistic view of mind which takes into account people have