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Anxiety and depression symptoms and migraine: a symptom-based approach research

Background Anxiety and mood disorders have been shown to be the most relevant psychiatric comorbidities associated with migraine, influencing its clinical course, treatment response, and clinical outcomes. Limited information is available on how specific anxiety and depression symptoms are related to migraine. Symptoms-based approach, a current trend in mental health research, may ...

Disrupted functional connectivity of periaqueductal gray subregions in episodic migraine

Background The periaqueductal gray (PAG) dysfunction was recognized in migraine, and the altered dysfunction of PAG subregions were not totally detected up to now. The aim of this study is to investigate the altered functional connectivity of PAG subregions in EM patients. Methods The brain structural images and resting state functional MR imaging (rs-fMRI) data were obtained from ...

The universe of ANA testing: a case for point-of-care ANA testing

Testing for total antinuclear antibodies (ANA) is a critical tool for diagnosis and management of autoimmune diseases at both the primary care and subspecialty settings. Repurposing of ANA from a test for lupus to a test for any autoimmune condition has driven the increase in ANA requests. Changes in ANA referral patterns include early or subclinical autoimmune disease detection in ...

Do general innovation policy tools fit all? Analysis of the regional impact of the Norwegian Skattefunn scheme

Background The paper examines the regional effects of a general innovation policy, i.e. a policy tool that does not target specific industries or subnational regions. General policy tools are an important part of the portfolio of innovation policy measures. However, there is a question over whether general tools are equally relevant for all types of firms, irrespective of their ...

Optimal nitrogen fertilization of boreal conifer forest

Background Forest fertilization offers a means to increase the production of renewable resources. Nitrogen is the most common fertilizer in boreal upland forests. There is plenty of research on the effect of nitrogen fertilization on volume growth, but less research on the optimal timing of fertilization and optimal management of fertilized stands. Methods This study used ...

Instrumental approach toward understanding nano-pollutants

Nano-pollutants (NPLTs) have recently raised global concerns due to their possible harmful impact on environment and human health. However, until date, information on the occurrence, fate and toxicity of NPLTs in environment is scant. The knowledge gap can be attributed to the lack of advanced and sophisticated methodologies for the precise detection and characterization of NPLTs ...

The micro-politics of small-scale fisheries governance in South Africa: a case study of community-based political representation as a form of brokerage

The right of small-scale fishers to participate in governance and management processes has been increasingly recognised by theorists and policy-makers over the last thirty years. Political representation is central to the realisation of the right to participation. In the context of small-scale fisheries, the first level of political representation is usually located within a ...

Perceptions of neighborhood environments and their association with overweight in children, adolescents, and caretakers in a medium-sized city in Brazil

Background Previous studies conducted in developed countries have suggested associations between perceptions of neighborhood characteristics and weight gain. However, there are few studies regarding the adult perception of the residential environment and overweight in children and adolescents in countries with low and medium income. The aim of the study was to assess the ...

Genome-wide Association Analysis Tracks Bacterial Leaf Blight Resistance Loci In Rice Diverse Germplasm

Background A range of resistance loci against different races of Xanthomonas oryzae pv. oryzae (Xoo), the pathogen causing bacterial blight (BB) disease of rice, have been discovered and characterized. Several have been deployed in modern varieties, however, due to rapid evolution of Xoo, a number have already become ineffective. The continuous “arms race” between Xoo and rice ...

Comparison of response patterns in different survey designs: a longitudinal panel with mixed-mode and online-only design

Background Increasing availability of the Internet allows using only online data collection for more epidemiological studies. We compare response patterns in a population-based health survey using two survey designs: mixed-mode (choice between paper-and-pencil and online questionnaires) and online-only design (without choice). Methods We used data from a longitudinal panel, the ...

Botulinum neurotoxin type A for the treatment of pain: not just in migraine and trigeminal neuralgia

Background Despite their huge epidemiological impact, primary headaches, trigeminal neuralgia and other chronic pain conditions still receive suboptimal medical approach, even in developed countries. The limited efficacy of current pain-killers and prophylactic treatments stands among the main reasons for this phenomenon. Botulinum neurotoxin (BoNT) represents a well-established ...

The FAST D protocol: a simple method to rule out traumatic vascular injuries of the lower extremities

Background The aim of this study is to assess the accuracy of a Fast Doppler protocol for the examination of an injured lower limb, namely 2-Point Fast Doppler (2PFD), in order to rapidly triage arterial lesions after penetrating trauma. Methods The presence of flow and the aspects of the Doppler waveform of the dorsalis pedis artery (DPA) and posterior tibial artery (PTA) of the ...

Data completion in building information management: electrical lines from range scans and photographs

Background The concept of building information management (BIM) is based on its holistic nature. This idea pays off, if all relevant information is fused into one consistent data set. As a consequence, the completeness of data is vital and the research question on how to complete data automatically remains open. Methods In this article we present a data completion technique based ...

Barriers and facilitators for BIM use among Swedish medium-sized contractors - “We wait until someone tells us to use it”

Background The pace of diffusion of BIM (Building Information Modelling) use is considered to increase with governmental initiatives in which public clients in countries like Finland, Singapore, United Kingdom, and Sweden begin requiring BIM as a part of the project delivery. Currently, larger contractor firms use BIM to a certain extent. However, BIM use by mid-sized contractor ...

The strength of co-authorship ties through different topological properties

Social networks are complex structures that describe individuals (graph nodes) connected in any social context (graph edges). Different metrics can be applied to those networks and their properties in order to understand behavior and even predict the future. One of such properties is tie strength, which allows to identify prominent individuals, analyze how relationships play ...

Automated guided vehicle mission reliability modelling using a combined fault tree and Petri net approach

Automated guided vehicles (AGVs) are being extensively used for intelligent transportation and distribution of materials in warehouses and autoproduction lines due to their attributes of high efficiency and low costs. Such vehicles travel along a predefined route to deliver desired tasks without the supervision of an operator. Much effort in this area has focused primarily on route ...

Arthrose multidimensional behandeln

Die letzten Jahre haben eine Vervielfachung unseres medizinischen Wissens gebracht. Die Zunahme der Evidenz bedeutet jedoch nicht, dass dieses Wissen auch fachgerecht an den Patienten herangebracht wird. Im Unterschied zu akuten Erkrankungen, bei denen Heilung mit exakten therapeutischen Schritten ermöglicht wird, stellen chronische Erkrankungen eine große Herausforderung in ...

Microwave Hydrothermal Synthesis of Terbium Ions Complexed with Porous Graphene for Effective Absorbent for Organic Dye

A luminescent terbium ions/reduced graphene oxide complex (Tb-RGO) was successfully and rapidly synthesized by the microwave hydrothermal reaction via the interactions between terbium ions and the active oxygen functional groups of graphene oxide. The as-prepared material was porous stacked by multilayer graphene in all directions. Thus, the resulting product owed the high specific ...

Primary pain generator identification by CT–SPECT in a patient with low back pain: a case report

Background Chronic low back pain is one of the most common conditions encountered in the middle-age population. Identifying the primary pain generator is notoriously difficult. The computed tomography–single-photon emission computed tomography (CT–SPECT) is emerging as a new diagnostic modality for this purpose. Case presentation This 68-year-old Caucasian male presented with ...

Should We Genetically Select for the Beauty Norm of Fair Skin?

Fair skin is often regarded as a beauty ideal in many parts of the world. Genetic selection for non-disease traits may allow reproducers to select fair skin for the purposes of beauty, and may be justified under various procreative principles. In this paper I assess the ethics of genetic selection for fair skin as a beauty feature. In particular, I explore the discriminatory ...